Bangalore, India
Bangalore, India

The next-generation network is body of key architectural changes in telecommunication core and access networks. The general idea behind the NGN is that one network transports all information and services by encapsulating these into packets, similar to those used on the Internet. NGNs are commonly built around the Internet Protocol, and therefore the term all IP is also sometimes used to describe the transformation of formerly telephone-centric networks toward NGN.The concept of future Internet refers instead to how the Internet itself might evolve. Wikipedia.

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Provided is a method for construction of bone substitutes efficient in the repair of large bone defects. The method for constructing such medical products includes three-dimensional printing of a bioresorbable scaffold and its activation by gene constructions. Produced medicinal products may serve as an efficient alternative to bone autografts.


A medical kit for analysis of vaginal biological samples includes a sample collector, an extractor, and an assay cartridge. The sample collector is compressible and insertable in a vaginal canal for collecting biological samples, and includes a cup-shaped head configured to cradle a cervical os. The extractor includes a sample receptacle configured to receive the sample collector via an open end. The extractor includes a compression mechanism with a compression element that is movable inwards into the open end of the sample receptacle to apply a compression force in response to activation of a release element. The extractor further includes a reservoir in fluid communication with the sample receptacle, the reservoir receiving the biological samples from the sample collector in response to the compression force being applied within the sample receptacle. The assay cartridge has a docking mechanism configured to fluidly communicate with the reservoir of the extractor.


The invention relates to medicine, particularly to the construction of the bone substitutes efficient in large bone defects repair. The inventive method for constructing such medical products includes three-dimensional printing of bioresorbable scaffold and its activation by gene constructions. Produced by proposed methods medicinal products may serve as an efficient alternative to bone autografts.


The invention relates to medicine, and more particularly to neurosurgery and trauma surgery, and can be used for stimulating nerve regeneration through the use of a gene therapeutic construct which codes for vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF-2). The gene therapeutic construct that codes for the two factors is based on a codon-optimized recombinant plasmid. The gene therapeutic construct can be introduced either directly into a damaged nerve or into the perineural tissues either during surgery or in the post-operative period. The invention significantly improves the outcomes of the reconstructive treatment of damaged peripheral nerves.


A nucleic acid or transgene comprising a modified VEGF 3-untranslated region (3-UTR) polynucleotide sequence and a polynucleotide sequence encoding a Vascular Endothelial Growth Factor (VEGF). When transformed into a host cell, the nucleic acid or transgene exhibits a high stability and provides prolonged and reliable expression of VEGF. A method for extending the lifetime of transgene mRNA encoding VEGF in a mammalian host cell. A method for treating a subject in need of increased or modified expression of VEGF using this nucleic acid or transgene.


Grant
Agency: Department of Defense | Branch: Air Force | Program: SBIR | Phase: Phase II | Award Amount: 374.89K | Year: 2016

Increasing system capabilities in terms of weapon systems, ISR payloads, GNC, etc., enabled by smaller and more capable electronics systems have led to a trend for overall size reduction in military aircraft. This has resulted in a reduction in the avail...


Grant
Agency: Department of Defense | Branch: Army | Program: SBIR | Phase: Phase II | Award Amount: 1000.00K | Year: 2016

The goal of the proposed Phase II research is to perfect the graphene dispersion and mixing techniques and demonstrate that the graphene enhanced double base propellant (GEP) is as insensitive as the base propellant. In Phase I, limited experimental evaluation.


Grant
Agency: Department of Defense | Branch: Army | Program: SBIR | Phase: Phase II | Award Amount: 995.33K | Year: 2015

Building upon a successful Phase I effort where we demonstrated the viability of multiple transparent conductive material to be used as an antenna as well as the self-healing properties of our polymer encapsulant we will test the transparent antenna patterns before selecting a final material to be used for further testing. The main focus of the proposed effort is to integrate the transparent antenna and self-healing polymer as an interlayer in the existing glass laminate manufacturing process, verify ballistic properties of the laminate, and demonstrate antenna performance post-impact. To aid in this objective we are teaming with GK Materials, who has exclusive rights to the SH polymer used in the Phase I, and American Defense Systems, who designs and sells of transparent armor to defense and commercial users.


Grant
Agency: National Aeronautics and Space Administration | Branch: | Program: SBIR | Phase: Phase I | Award Amount: 121.63K | Year: 2016

The innovation is a fast, lightweight, and miniaturized Robotic Variable Interference Filter Imaging Spectrometer (R-VIFIS) for a 350-2500nm wavelength range. A pair of custom narrow band Linear Variable Interference Filters (LVIFs) is tailored with 350-900nm range (VNIR) and 900-2500nm range (SWIR) wedge coatings for a 35mm format CMOS Focal Plane Array (FPA) and a 384x288 pixel 24um pitch FPA respectively. A pair of monolithic LVIF-FPA devices, each having its VNIR or SWIR LVIF coating precisely aligned and mounted in contact with its FPA sensing surface, are designed and assembled. Miniaturized robotic devices are developed to precisely position the LVIF-FPAs at a fast speed. A prototype R-VIFIS integrates fast frame robotic positioning LVIF-FPAs behind a pair of co-boresighted 35mm film format lenses for fast LVIF HyperSpectral Imaging (HSI), taking 224 contiguous spectral bands into a 350-2500nm range datacube in 300 and a spectral resolution of 1% center wavelength at each band. Tightly integrated with GPS/INS with real time embedded computing, R-VIFIS collects directly georeferenced photographic perspective HSI measurement with a throughput up to 1.65GB/sec, providing simultaneously high spectral, spatial, radiometric, and temporal resolutions. A typical R-VIFIS photographic perspective datacube, consisting of well fused 6480x5400 pixel VNIR bands and 1580 x1300 pixel SWIR bands. R-VIFIS is versatile and easily-deployable. It is operational on a tripod, surface vehicles, aerostats, and fixed/rotating wing aerial platforms for field/aerial 3D imaging spectroscopy. It is also well suited to be gimbaled for wide angular field of view and long distance enhanced remote sensing.


Grant
Agency: National Aeronautics and Space Administration | Branch: | Program: STTR | Phase: Phase I | Award Amount: 115.82K | Year: 2016

NextGen Federal Systems proposes an innovative SPace Radiation INTelligence System (SPRINTS) which provides an interactive and web-delivered capability that significantly improves long-range forecasts (2-3 days), all-clear forecasts, and forecast accuracies of solar particle events (SPEs). SPRINTS provides SPE-related data, visualizations, and forecasts that leverage and integrate two complimentary and cutting-edge foundational space weather systems: Magnetogram Forecast (Mag4) and Space Weather Information System (SWIS). The integration of these two capabilities with the addition of an intuitive/interactive user interface and advanced data analysis/forecasting capabilities provides SPRINTS users with the unique ability to effectively explore SPE data and forecasts relevant to their asset(s) and data needs. While leveraging and delivering the forecasts produced by Mag4, the SPRINTS forecast system will use machine-learning and expert-guided statistical analyses to explore new models based, not only on data provided by Mag4 and SWIS, but designed to incorporate other SPE-relevant datasets. SPRINTS also incorporates information about specific space and airborne assets that are entered by individual users and organizations. This information will be integrated with the SPRINTS radiation environment models and engineering models of the predicted impact of SPEs to specific hardware and instruments. SPRINTS serves as a platform to deliver SPE-based operational products covering monitoring, forecasting, and impact analysis of SPEs to help define mission planning, operations, evaluation, and safety.

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