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Meric K.,University of Minnesota | Killeen R.P.,Weill Cornell Medical Center NewYork Presbyterian Hospital | Abi-Ghanem A.S.,Weill Cornell Medical Center NewYork Presbyterian Hospital | Soliman F.,Weill Cornell Medical Center NewYork Presbyterian Hospital | And 3 more authors.
Clinical Imaging | Year: 2015

Objective: This study examined the use of positron emission tomography (PET) ratios to improve the diagnostic ability of 18F-FDG PET/computed tomography (CT) in the differentiation of enhancing brain metastases, central nervous system lymphomas, and gliomas. Materials and methods: Seventy-six patients with malignant brain tumors and available magnetic resonance imaging and PET/CT examinations were included. Results: Among standardized uptake value (SUV)-related parameters tested, tumor maximum SUV to ipsilateral cortex maximum SUV ratio (Tmax:WMimax) and maximum SUV (SUVmax) proved to be the two most valuable parameters for differential diagnosis. Conclusion: In addition to SUVmax, Tmax:WMimax also seems to provide helpful information for the differential diagnosis of lymphomas from other malignant brain tumors. © 2015 Elsevier Inc. Source

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