New York City, NY, United States

New York University

www.nyu.edu
New York City, NY, United States

New York University is a private, nonsectarian American research university based in New York City. NYU's main campus is located at Greenwich Village in Lower Manhattan. Founded in 1831, NYU is one of the largest private nonprofit institutions of American higher education.NYU was elected to the Association of American Universities in 1950. NYU counts 35 Nobel Prize winners, three Abel Prize winners, 10 National Medal of Science recipients, 16 Pulitzer Prize winners, over 30 Academy Award winners, four Putnam Competition winners, Russ Prize, Gordon Prize, and Draper Prize winners, Turing Award winners, and Emmy, Grammy, and Tony Award winners among its faculty and alumni. NYU also has MacArthur and Guggenheim Fellowship holders as well as National Academy of science and National Academy of Engineering members among its past and present graduates and faculty.NYU is organized into more than 20 schools, colleges, and institutes, located in six centers throughout Manhattan and Downtown Brooklyn, as well as more than a dozen other sites across the world, with plans for further expansion. According to the Institute of International Education, NYU sends more students to study abroad than any other US college or university, and the College Board reports more online searches by international students for "NYU" than for any other university. Wikipedia.


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Disclosed herein are isolated and purified Staphylococcus aureus bi-component leukocidin, referred to herein as LukAB, and its components LukA and LukB, antibodies specific to LukA, antibodies specific to LukB, therapeutic compositions containing LukA and/or LukB, or anti-LukA and/or anti-LukB antibodies, uses of the compositions to treat acute inflammatory conditions or S. aureus infection, methods for identifying inhibitors of LukAB-mediated cytotoxicity of human phagocytes, and methods for using LukAB as a marker to predict severity of S. aureus infection.


Patent
New York University | Date: 2017-03-01

The present invention relates to methods for preventing or treating Human Immunodeficiency Virus (HIV) infection, inflammatory conditions, and graft-versus-host-disease (GVHD) in a subject. Therapeutic compositions of the present invention comprise Leukocidin E (LukE) and/or D proteins or polypeptides. The invention further relates to methods of treating Staphylococcus aureus infection by administering a composition comprising a CCR5 antagonist or any molecule that blocks LukE/D interaction with CCR5^(+) cells in an amount effective to treat the S. aurreus infection in the subject.


Patent
Toshiba Corporation and New York University | Date: 2017-02-22

An X ray diagnostic apparatus includes an X ray tube generating X rays, a first detector detecting the X rays, at least one second detector arranged in front of a first detection surface of the first detector and including a second detection surface narrower than the first detection surface and indicator points provided on a rear surface of the second detection surface, a projection data generation unit generating first projection data based on an output from the first detector, and a positional shift detection unit detecting a positional shift of the second detector relative to the first detector in accordance with an imaging direction by using the first projection data and a predetermined positional relationship between the points and detection elements in the second detector.


Patent
New York University | Date: 2017-02-21

The invention relates to the field of polymers and olefin polymerization, and more specifically olefin metathesis polymerization. The invention provides regioregular alternating polymers and methods of synthesizing such polymers. To demonstrate, polymers were synthesized and modified with a FRET pair (Trp/Dansyl) post-polymerization.


Patent
New York University | Date: 2017-03-03

The present disclosure is directed to adeno-associated viral vector monoclonal antibody constructs and compositions thereof, methods of improving locomotor function after spinal cord injury, methods of treating neurodegenerative diseases.


Patent
New York University | Date: 2017-03-13

The compositions and methods described herein are designed to introduce functionalized microparticles into droplets that can be manipulated in microfluidic devices by fields, including electric (dielectrophoretic) or magnetic fields, and extracted by splitting a droplet to separate the portion of the droplet that contains the majority of the microparticles from the part that is largely devoid of the microparticles. Within the device, channels are variously configured at Y- or T junctions that facilitate continuous, serial isolation and dilution of analytes in solution. The devices can be limited in the sense that they can be designed to output purified analytes that are then further analyzed in separate machines or they can include additional channels through which purified analytes can be further processed and analyzed.


Exemplary communication apparatus comprising a MAC-layer processor configured to receive data for a downlink transmission to a first device; transmit a grant comprising resource allocations for the device to receive the data and to transmit a reception status for the data; and transmit the first grant and at least part of the data in a symbol. The grant can also be frequency-multiplexed with another grant to another device in the symbol, which can also be spatially multiplexed in streams directed to the respective devices. Other embodiments include determining a resource allocation for a device that encompasses resources previously allocated to at least one other device but comprises an indicator that such resource is unavailable to the device. Exemplary methods and computer-readable media can also be provided embodying one or more procedures the apparatus is configured to perform.


Patent
Membrane Technology, Research, Inc. and New York University | Date: 2017-03-30

A process for separating components of a gas mixture using gas-separation copolymer membranes. These membranes use a selective layer made from copolymers of an amorphous perfluorinated dioxolane and a fluorovinyl monomer. The resulting membranes have superior selectivity performance for gas pairs of interest while maintaining fast gas permeance compared to membranes prepared using conventional perfluoropolymers, such as Teflon AF, Hyflon AD, and Cytop.


Patent
University of Arizona, New York University, Redaelli and Rasponi | Date: 2017-07-05

Provided herein is technology relating to microfluidic devices and particularly, but not exclusively, to devices, methods, systems, and kits for imparting stresses on a fluid flowing through a microfluidic device that is designed to mimic a stress profile of a macrofluidic device or pathology.


Seeman N.C.,New York University
Annual Review of Biochemistry | Year: 2010

The combination of synthetic stable branched DNA and sticky-ended cohesion has led to the development of structural DNA nanotechnology over the past 30 years. The basis of this enterprise is that it is possible to construct novel DNA-based materials by combining these features in a self-assembly protocol. Thus, simple branched molecules lead directly to the construction of polyhedrons, whose edges consist of double helical DNA and whose vertices correspond to the branch points. Stiffer branched motifs can be used to produce self-assembled two-dimensional and three-dimensional periodic lattices of DNA (crystals). DNA has also been used to make a variety of nanomechanical devices, including molecules that change their shapes and molecules that can walk along a DNA sidewalk. Devices have been incorporated into two-dimensional DNA arrangements; sequence-dependent devices are driven by increases in nucleotide pairing at each step in their machine cycles. © 2010 by Annual Reviews. All rights reserved.

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