Daejeon, South Korea
Daejeon, South Korea

Time filter

Source Type

The present invention relates to a pharmaceutical composition and a cosmetic composition, which contain, as an active ingredient, a novel pseudo compound having similar structural characteristics to natural ceramide 1, or a pharmaceutically acceptable salt or solvate thereof, and the composition containing the compound of the present invention as an active ingredient has an excellent effect of enhancing a skin barrier function, thereby exhibiting an effect of alleviating inflammatory skin diseases, and has an excellent skin barrier improving function and an excellent skin moisturization enhancing effect.


Provided is a transdermal drug delivery system, which is a delivery system for transdermal absorption, having a multi-lamellar emulsion structure, including: lipids including long-chain amides, sterols, fatty acid and fatty alcohol; an emulsifier; oil; and at least one drug for transdermal administration. The transdermal drug delivery system in a multi-lamellar emulsion structure, according to the present invention, has a lamellar structure in which a layered structure visible in stratum corneum intercellular lipids of the human body is repeated, and thus has an excellent skin barrier effect and enables a drug to be effectively partitioned through skin lipids, thereby obtaining an excellent drug delivery effect.


Patent
Neopharm Co. | Date: 2016-12-14

The present invention relates to a composition for promoting hair growth, preventing hair loss, or relieving inflammation, and more specifically, to a composition which has excellent stability to the skin, has no side effects, and exhibits excellent effects of hair growth promotion and hair loss prevention by promoting hair growth and delaying hair loss. The composition according to the present invention contains a material belonging to a ceramidase inhibitor, glycol, C1-C5 lower alcohol, and water, and thus the composition is safe, has no side effects, can be continuously used for a long period of time, has an excellent effect of hair growth promotion or hair loss prevention by significantly promoting hair growth, and exhibits an inflammation relieving effect as well as a hair growth promoting effect, additionally.


Patent
Neopharm Co. | Date: 2016-04-20

Disclosed are immunological compositions and methods for reducing activity of glucagon signaling using antibodies against glucagon receptor.


Patent
Neopharm Co. | Date: 2015-01-27

The present invention relates to a composition for promoting hair growth, preventing hair loss, or relieving inflammation, and more specifically, to a composition which has excellent stability to the skin, has no side effects, and exhibits excellent effects of hair growth promotion and hair loss prevention by promoting hair growth and delaying hair loss. The composition according to the present invention contains a material belonging to a ceramidase inhibitor, glycol, C1-C5 lower alcohol, and water, and thus the composition is safe, has no side effects, can be continuously used for a long period of time, has an excellent effect of hair growth promotion or hair loss prevention by significantly promoting hair growth, and exhibits an inflammation relieving effect as well as a hair growth promoting effect, additionally.


Provided is a transdermal drug delivery system, which is a delivery system for transdermal absorption, having a multi-lamellar emulsion structure, including: lipids including long-chain amides, sterols, fatty acid and fatty alcohol; an emulsifier; oil; and at least one drug for transdermal administration. The transdermal drug delivery system in a multi-lamellar emulsion structure, according to the present invention, has a lamellar structure in which a layered structure visible in stratum corneum intercellular lipids of the human body is repeated, and thus has an excellent skin barrier effect and enables a drug to be effectively partitioned through skin lipids, thereby obtaining an excellent drug delivery effect.


Patent
Neopharm Co. | Date: 2015-10-07

The composition of external application to the skin according to the present invention may specifically control the relative amount between long-chain amides and sterols and the relative amount between lipid components and an emulsifier in the emulsion having a multi-layered lamella structure, the emulsion comprising a relatively larger content of dermatologically useful hydrophobic material in a formulation. Thus, the formulation having significantly high stability and excellent characteristics can be obtained in spite of the high content in the lipid components and the emulsifier.


The present invention relates to a weakly acidic composition for skin external application, which comprises a pH adjuster, a polymeric thickener and a multi-lamellar emulsion and has a pH of 3-5, preferably 3-4.5, and to a cosmetic formulation comprising the composition. The multi-lamellar emulsion in the weakly acidic composition of the present invention contains large amounts of dermatologically useful oleophilic substances, has skin barrier function, and is stably maintained at a relatively low pH, and thus the composition normalizes the pH of the skin to enhance or restore the skins barrier function to thereby restore and maintain the skin in a healthy state, and effectively moisturizes the skin. In addition, the composition is maintained at suitable viscosity so as to be effectively prevented from phase separation. Also, the composition does not penetrate the skin, and thus causes no skin irritation.


The present invention relates to a novel pseudoceramide derivative, a pharmaceutically acceptable salt thereof or a solvate thereof, and a pharmaceutical or cosmetic composition containing the same as an active ingredient. The novel pseudoceramide derivative of the present invention is expected to be very useful for treating or preventing skin diseases by activating cannabinoid receptors. In addition, the novel pseudoceramide derivative, the pharmaceutically acceptable salt thereof or the solvate thereof, of the present invention, has a simple synthesis process compared with a known cannabinoid receptor antagonist so as to reduce processing time and curtail material costs, and thus is economical, and has advantages such as easy emulsification during the formulation of cosmetic products or medical supplies.


The present invention relates to a composition with a pH of 3-5, preferably 3-4.5 externally used for a subacid skin composed of a multi-lamellar emulsion including pH modulation agent and a polymeric thickening agent, and a composition externally used for a subacid skin according to the present invention maintains stably a multi-lamellar emulsion with a skin barrier function composed of a large amount of a lipophilic skin care material at a relatively low pH condition so as to enhance or recover the skin barrier function through normalizing the skin pH, thus recovering and maintaining a healthy skin, making the skin effectively moisturized, maintaining a proper viscosity so as to prevent the phase separation, and having almost no skin penetration so as to eliminate the problem of stimulating the skin.

Loading Neopharm Co. collaborators
Loading Neopharm Co. collaborators