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Halder S.,Burdwan Medical College | Banerjee S.,Nb Medical College | Halder A.,Burdwan Medical College | Seth J.,Burdwan Medical College
Journal of Pakistan Association of Dermatologists | Year: 2011

Cancer of unknown primary (CUP) origin is the diagnosis when metastatic cancer is found but the primary site cannot be determined. The peculiarity of our case is eleven months after the occurrence of two lesions of florid cutaneous metastases, the primary tumor or metastasis to a second organ could still not be identified despite thorough investigation.

Kumar K.,IPGMER | Kole A.K.,Nb Medical College | Karmakar P.S.,IPGMER | Ghosh A.,IPGMER
Rheumatology International | Year: 2012

To study the spectrum of thyroid disorders in systemic lupus erythematosus (SLE). Hundred SLE patients as per American Rheumatology Association(ARA) classification criteria underwent clinical examination, including assessment of disease activity (SLEDAI) and laboratory evaluation for serum triiodothyronine (T3),free thyroxine (FT4), thyroid stimulating hormone (TSH), antithyroperoxidase (TPO) antibody and antithyroglobulin (TG) antibody. Hundred age- and sex-matched apparently healthy individuals served as control. Thirty-six (36%) lupus patients had thyroid dysfunction when compared to 8 (8%) of controls and all of them were women. Primary hypothyroidism was the commonest dysfunction in 14 (14%), while subclinical hypothyroidism and subclinical hyperthyroidism was seen in 12 (12%) and 2 (2%), respectively. Eight (8%) had isolated low T3 consistent with sick euthyroid syndrome. Eighteen (50%) of thyroid dysfunction were autoimmune in nature (autoantibody positive) and rest 18 (50%) were non-autoimmune. Euthyroid state with the elevation of antibodies alone was seen in 12 (12%) of the lupus patients. In contrast, only 5 (5%) of controls had primary hypothyroidism and 3 (3%) had subclinical hypothyroidism, while none had hyperthyroidism. SLEDAI score and disease duration were compared between lupus patients with thyroid dysfunction to those with normal thyroid function. A statistically significant association was found between SLEDAI and thyroid dysfunction of sick euthyroid type.SLE disease duration had no statistically significant association with thyroid dysfunction. Prevalence of thyroid autoantibodies in lupus patients was 30% when compared to 10% of controls. Ninety-six (96%) of the SLE patients were ANA positive, while 4 (4%) of them were ANA negative but were anti-Sm antibody positive. There were no suggestions of any other autoimmune endocrine diseases like diabetes or Addison's disease (clinically and on baseline investigations) in our lupus cohort and hence no further work up was done for these diseases. Thyroid disorders are frequent in SLE and are multifactorial with a definite higher prevalence of hypothyroidism as well as thyroid autoantibodies. © 2010 Springer-Verlag.

Prasad R.,Nb Medical College | Majumdar Giri A.,Nb Medical College | Biswas J.,Nb Medical College | Kumar V.,Nb Medical College | And 2 more authors.
Indian Journal of Forensic Medicine and Toxicology | Year: 2015

A fatal case of accidental diesel (high speed) ingestion was brought to Department of Forensic Medicine, North Bengal Medical College for Medico-legal autopsy with a history of accidental ingestion 12 days ago followed by hospitalisation as a case of chemical pneumonitis. The macroscopic autopsy findings supported by histopathological examination findings are being displayed in the poster presentation. © 2015, Indian Journal of Forensic Medicine and Toxicology. All rights reserved.

Bagchi K.,Nb Medical College | Giri A.,Nb Medical College | Sarkar R.,Nb Medical College | Das S.,Nb Medical College | And 2 more authors.
Journal of the Indian Medical Association | Year: 2010

In a 3-year study with mass lesions related to ophthalmology 30 cases arising from ocular tissue, ocular adenaxae and orbit were subjected to fine needle aspiration biopsy. Of these 27 cases were further subjected to detailed histopathological examination. Fine needle aspiration biopsy revealed definitive cytological character in 23 cases consistent with histopathological and clinical diagnosis.

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