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Karjigi S.,Navodaya Medical College Hospital | Herakal K.,Navodaya Medical College Hospital | Murthy S.C.,VIMS | Bathina A.,Navodaya Medical College Hospital | And 2 more authors.
Indian Journal of Leprosy | Year: 2015

Leprosy has been increasingly known to have an enigmatic relationship with human immunodeficiency virus infection. Co-infection may result in atypical manifestations of leprosy. A 45-year old human immunodeficiency virus- positive male, agricultural laborer presented with a swelling over right elbow, right hand deformity, generalized itching and recurrent vesicles over the perinasal area. Clinical and investigational findings were consistent with mononeuritic type of Hansen's disease with right sided silent ulnar nerve abscess, partial claw hand. CD4+ count of the patient was 430 cells/ cmm. This patient also hadherpes simplex labialis, with HIV-associated pruritus. To the best of our knowledge such an atypical presentation has not been reported earlier. © Hind Kusht Nivaran Sangh, New Delhi. Source


Karjigi S.,Navodaya Medical College Hospital | Murthy S.C.,VIMS | Kallappa H.,Navodaya Medical College Hospital | Kusuma M.R.,Navodaya Medical College Hospital | Reddy Y.N.K.,Navodaya Medical College Hospital
Indian Journal of Leprosy | Year: 2015

Dapsone, a potent anti-inflammatory compound, is mainly used in the treatment of leprosy, dermatitis herpetiformis, erythema elevatum diutinum and other dermatoses. Cutaneous adverse reactions range from acneiform eruptions to toxic epidermal necrolysis. A 30-year-old, married women who was treated with paucibacillary multi drug therapy, developed itchy skin lesions over both forearms, ' V 'area of the neck and upper back after one week of the drug administration which worsened on exposure to sunlights. A clinical diagnosis of dapsone-induced photosensitive dermatitis was confirmed by histopathology and recurrence of symptoms and signs after re-exposure to the drug. Photosensitivity due to dapsone is rare and very few reports are available in the literature. Our patient had an unusually early onset compared to the previously reported cases. © Hind Kusht Nivaran Sangh, New Delhi. Source

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