Rāichūr, India
Rāichūr, India

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Kulkarni R.P.,Cochin Medical College | Kodliwadmath M.V.,Navodaya Medical College
International Journal of Pharma and Bio Sciences | Year: 2013

Indians as an ethnic group have a higher risk of type 2 diabetes mellitus, most likely due to genetic susceptibility. Diabetic retinopathy is one of the most devastating microvascular complications of diabetes mellitus1 and it is the most common cause of blindness. Oxidative stress plays an important role in the pathogenesis of microvascular and macrovascular complications of diabetes mellitus2. High sensitivity C-Reactive Protein (hsCRP) is a significant marker of inflammation and plays an important role in the pathogenesis of diabetic retinopathy. Fasting blood samples were collected from healthy controls, diabetics without retinopathy and with retinopathy. Serum malondialdehyde (MDA), vitamin C and vitamin E were estimated as a marker of oxidative stress. Serum hsCRP was estimated to validate its usefulness in gauging the severity of diabetic retinopathy. Our study showed a significant increase in serum MDA and decrease in serum antioxidant vitamins in diabetic retinopathy as compared to diabetics without retinopathy (p<0.001). Our study demonstrated increased serum hsCRP in diabetics with retinopathy as compared to those without retinopathy (p<0.001). Our study clearly indicates a close relationship between oxidative stress and diabetic retinopathy. Supplementation of anti-oxidants may prevent or delay onset of diabetic retinopathy. Increased hsCRP in diabetic retinopathy points to its usefulness in risk stratification.


Ashish J.,Sree Gokulam Medical College | Vinay H.,Navodaya Medical College
International Journal of Pharma and Bio Sciences | Year: 2013

Background Methicillin-resistant Staphylococcus aureus (MRSA) one of the most widespread causes of nosocomial infection's worldwide. Recently, they have been recovered from community. This study was undertaken to analyze the prevalence of methicillin resistance among isolates at Sree Gokulam Medical College, Trivandrum, and document the current resistance profile of MRSA and methicillinsensitiveStaphylococcus aureus (MSSA) to the commonly used anti-staphylococcal agents. Methods Over a 2-year period we analyzed 1215 isolates of S. aureus strains recovered from various clinical sources, from hospital and community practices. Antimicrobial susceptibility testing was done according to CLSI guidelines. Results The prevalence of MRSA from surgical/burn wounds/pus, urine and miscellaneous others were 60.1%, 15.5% and 6.6%, respectively. The major sources of MSSA were surgical/burn wounds, pus/abscess and upper respiratory tract specimens with rates of 32.9%, 17.1% and 14.3%, respectively. The greatest prevalence of resistance of MRSA along with beta lactams was seen for erythromycin (86.7%), and clindamycin (70%). Resistance rates among MSSA were highest for ampicillin (70%). Conclusion The prevalence of MRSA in the hospital increased from 12.5% in 2011 to 20.8% in 2013. Most isolates were associated with infected surgical/burn wounds which may have become infected via the hands of health care workers during dressing exercises. Infection control measures aimed at the proper hand hygiene procedures may interrupt the spread of MRSA. health care workers may also be carriers of MRSA in their anterior nares. Surveillance cultures of both patients and health care workers may help to identify carriers who would be offered antibiotics to eradicate the organisms. Most MRSA are resistant to several non-β-lactam antibiotics. Frequent monitoring of susceptibility patterns of MRSA and the formulation of a definite antibiotic policy may be helpful in decreasing the incidence of MRSA infection.


Viswanatha B.,Bangalore Medical College and Research Institute and 716 | Naseeruddin K.,Navodaya Medical College
Indian Journal of Otolaryngology and Head and Neck Surgery | Year: 2014

Thrombosis of the lateral sinus can be classified into nonseptic lateral sinus thrombosis and septic lateral sinus thrombosis. Nonseptic lateral sinus thrombosis differs from septic lateral sinus thrombosis in that it is not associated with ear or sinus infection. Etiologies of these conditions are different and hence the management of these conditions is different. Nonseptic lateral sinus thrombosis requires medical line of management and anticoagulant therapy, where as septic lateral sinus thrombosis needs surgical treatment along with antibiotics therapy. An otologist should be familiar with the septic lateral sinus thrombosis existence and nonseptic variant lateral sinus thrombosis for early recognition and initiation of appropriate treatment. © 2011 Association of Otolaryngologists of India.


Somannavar M.S.,KLE University | Kodliwadmath M.V.,Navodaya Medical College
European Review for Medical and Pharmacological Sciences | Year: 2012

Background and Objectives: The diet is a key environmental factor implicated in health and disease. Oxidative stress, antioxidant status and their relation to diet is a subject of interest in recent years. The objective of the study was to compare lipid peroxidation and antioxidant status in healthy vegetarians and non-vegetarians. Methods: The present study comprises100 healthy individuals (50 vegetarians and 50 nonvegetarians) residing in Belgaum urban area. All the participants were in the age group of 40-60 years of both sexes. This cross-sectional study was done in one year period from April 2007 to March 2008. Malondialdehyde (MDA) (lipid peroxidation product) was estimated by thiobarbituric acid method, glutathione peroxidase by Beutler's method, Vitamin A and Vitamin E by Bessay et al and Quife et al methods respectively. Results: Our study revealed that the blood MDA level was significantly increased (p value < 0.001) in non-vegetarians compared to lactovegetarians and lacto-ovo-vegetarians. There was significant decrease in the level of enzymatic antioxidant glutathione peroxidase and non-enzymatic antioxidants Vitamin A and Vitamin E in non-vegetarians compared to lactovegetarians and lacto-ovo-vegetarians (p value <0.001). Conclusions: Results of this investigation present study indicate that there was an increased lipid peroxidation and a low antioxidant status in non-vegetarians compared to vegetarians. Vegetarian nutrition provides adequate antioxidants which effectively prevent free radicals generation.


Patil D.,Navodaya Medical college
Indian Journal of Forensic Medicine and Toxicology | Year: 2013

Deaths due to poisoning are more in developing countries and methods of poisoning varies from one place to other. Hence to know the pattern of poisoning, a retrospective study was done at a district hospital, Raichur (Karnataka) between the years 2009 -2012. During this period 302 cases of poisoning deaths were autopsied. These poisoning cases were studied to know age and sex distribution of the victims, commonest type of poisons used and manner of poisoning. In this study, majority 220 (72.85%) of the cases were due to organophosphorus compound, followed by snake bite 30 (9.93%), aluminium phosphide 21 (6.95%) and others respectively.


Patil D.,Navodaya Medical College
Indian Journal of Forensic Medicine and Toxicology | Year: 2013

In the present study 128 cases of head injury victims in fatal vehicular accidents autopsied are included. In vehicular accidents, among 128 cases studied who died due to fatal cranio-cerebral injuries, males were the commonest victims, 21-40 years was the common age group. Temporal and frontal bones were the commonest sites of fracture. Subdural hemorrhage was the commonest among the intracranial hemorrhages.


Patil D.,Navodaya Medical College
Medico-Legal Update | Year: 2014

100 patients diagnosed as suffering from diabetes mellitus were included for the study. The male patients were 50 in number and the female patients were 50 in number. About 50 male and 50 female volunteers were included as control group. The finger print patterns observed between diabetic individuals and controls. Diabetic patients showed increase in frequency of number of whorls as compared to control group. This finding was common to both the sex. Diabetic patients also showed decrease infrequency of ulnar loops as compared to the control group. This finding was also common to both the sexes. © 2014, World Informations Syndicate, All Rights Reserved.


Patil D.,Navodaya Medical College
Medico-Legal Update | Year: 2014

Poisoning is one of the causes for morbidity and mortality in developing countries and methods of poisoning varies from one place to other. Hence to know the pattern of poisoning, a retrospective study of 150 cases was done at a Navodaya Medical college Hospital, Raichur (Karnataka) between Jan-June 2013. During this period 150 cases of poisoning cases were studied. These poisoning cases were studied to know the age and sex distribution of the victims, commonest type of poisons used and manner of poisoning. In this study, majority 106 (71%) of the cases were due to organophosphorus compound, followed by snake bite 14 (9%), aluminium phosphide 11 (8%) and others respectively. © 2014, World Informations Syndicate, All Rights Reserved.


Patil D.,Navodaya Medical College
Medico-Legal Update | Year: 2014

This study was conducted on 250 patients who visited the casualty of District Hospital, Raichur, Karnataka, India. The objective of the study was to know the pattern of cases in the casualty of a district hospital and to analyse the case mix pattern of emergency cases in the casualty. General Medicine & its allied speciality contributed to the maximum number of patients attending the casualty. Maximum number of the patients visiting the casualty had minor complaints and did not suffer from any serious or life threatening problem, which actually required admission and emergency medical care. This results in increase workload of the casualty staff working mainly for providing emergency care in the hospital. © 2014, World Informations Syndicate, All Rights Reserved.


Itagi V.,Navodaya Medical College | Patil R.,Navodaya Medical College
Turkish Journal of Medical Sciences | Year: 2011

Aim: It is difficult to project the prevalence of obesity and overweight among children in India since there is no nationally representative data from India. We determined the time trends in childhood obesity in a representative sample of schoolchildren from Raichur District, Karnataka and investigated the relationship of obesity with blood pressure. Materials and methods: We used a stratified random cluster sampling method to select the children. Anthropometric data were collected from 23,842 students, 5-16 years of age, during 2005-06. Blood pressure and anthropometric data were collected from 19,263 students during 2007-08. Overweight and obesity were defined by body mass index for gender and age. Gender, age, and height were considered for determining hypertension. Results: The rate of overweight children increased from 4.94% of the total students in 2005 to 6.57% in 2007 (OR: 1.36; 95% CI: 1.25-1.47; P < 0.0001). The increase was significant in both boys and girls. The rate of overweight children was significantly higher in urban regions and in private schools, and the rising trend was limited to private schools. Systolic or diastolic incident hypertension was found in 17.34% of overweight children versus 10.1% of the remaining students (OR: 1.87; 95% CI: 1.60-2.17; P < 0.0001). Conclusion: The present study shows that, childhood obesity showed a rising trend in a period of 2 years. The results put forward the need for greater public awareness and prevention programmes on childhood obesity and hypertension. Hypertension was common in overweight children. Overweight is a rising health problem in children and adolescents in Raichur city. © TÜBITAK.

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