Washington, DC, United States
Washington, DC, United States

Time filter

Source Type

Lu Q.,Naval Research Laboratory 4555 Overlook Ave | Terray A.,Naval Research Laboratory 4555 Overlook Ave | Collins G.E.,Naval Research Laboratory 4555 Overlook Ave | Hart S.J.,Naval Research Laboratory 4555 Overlook Ave
Lab on a Chip - Miniaturisation for Chemistry and Biology | Year: 2012

A unique microfluidic system is developed which enables the interrogation of a single particle by using multiple force balances from a combination of optical force, hydrodynamic drag force, and electrophoretic force. Two types of polystyrene (PS) particles with almost identical size and refractive index (plain polystyrene (PS) particle - mean diameter: 2.06 μm, refractive index: 1.59; carboxylated polystyrene (PS-COOH) particles - mean diameter: 2.07 μm, refractive index: 1.60), which could not be distinguished by optical chromatography, reveal different electrokinetic behaviors resulting from the difference in their surface charge densities. The PS-COOH particles, despite their higher surface charge density when compared to the PS particles, experience a lower electrophoretic force, regardless of ionic strength. This phenomenon can be understood when the more prominent polarization of the counter ion cloud surrounding the PS-COOH particles is considered. The surface roughness of the carboxylated particles also plays an important role in the observed electrokinetic behavior. © 2012 The Royal Society of Chemistry.

Loading Naval Research Laboratory 4555 Overlook Ave collaborators
Loading Naval Research Laboratory 4555 Overlook Ave collaborators