Natural Products and Glycotechnology Research Institute Inc.

River Road, NC, United States

Natural Products and Glycotechnology Research Institute Inc.

River Road, NC, United States

Time filter

Source Type

Ramamurty C.V.S.,Natural Products and Glycotechnology Research Institute Inc. | Ganney P.,Natural Products and Glycotechnology Research Institute Inc. | Rao C.S.,CiVentiCHEM | Fraser-Reid B.,Natural Products and Glycotechnology Research Institute Inc.
Journal of Organic Chemistry | Year: 2011

The 3,5-di-O-benzoyl n-pentenyl orthoesters of the four pentofuranoses have been prepared. The first key intermediate in each case is the methyl pentofuranoside(s), and a user-friendly procedure for the preparation of each, based on the Callam-Lowary precedent, is described, whereby formation of the crucial α/β anomeric mixture is optimized. The mixture is used directly to prepare the corresponding perbenzoylated pentofuranosyl bromide(s) and then the title compounds. © 2011 American Chemical Society.


Fraser-Reid B.,Natural Products and Glycotechnology Research Institute Inc. | Ganney P.,Natural Products and Glycotechnology Research Institute Inc. | Ramamurty C.V.S.,Natural Products and Glycotechnology Research Institute Inc. | Gomez A.M.,Institute Quimica Organica General IQOG CSIC | Lopez J.C.,Institute Quimica Organica General IQOG CSIC
Chemical Communications | Year: 2013

Strategically derivatized NPOE glycosyl donors, are able to efficiently glycosylate silylated nucleobases under mild conditions, even as low as -78°C if necessary. Ensuring trans-1,2 glycosylation, thus permitting, unlike classical procedures, a Reverse Strategy for the synthesis of ribonucleosides, where glycosylation occurs late, rather than early, and convergency is optimized. © 2013 The Royal Society of Chemistry.

Loading Natural Products and Glycotechnology Research Institute Inc. collaborators
Loading Natural Products and Glycotechnology Research Institute Inc. collaborators