The National University of Ireland, Galway is a constituent university of the National University of Ireland. It is a tertiary-level educational institution located in Galway, Ireland. The university was founded in 1845 as Queen's College, Galway and was more recently known as University College, Galway . Wikipedia.
National University of Ireland | Date: 2015-02-16
National University of Ireland | Date: 2015-02-12
A population of human stem cells is, or is selected to be, positive for CD271 and acetylated tubulin. Cells are isolated by a method comprising isolation of a cell from a mixed population of cells based on expression of cell surface markers, wherein the markers are CD271 and acetylated tubulin. The isolated cells may be used in therapy for example by producing tissues such as bone, cartilage or tendon, or in pharmaceutical compositions comprising isolated cells.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: BG-01-2016 | Award Amount: 12.22M | Year: 2017
The GENIALG project aims to boost the Blue Biotechnology Economy (BBE) by increasing the production and sustainable exploitation of two high-yielding species of the EU seaweed biomass: the brown alga Saccharina latissima and the green algae Ulva spp. GENIALG will demonstrate the economic feasibility and environmental sustainability of cultivating and refining seaweed biomass in multiple use demanded products of marine renewable origin. The consortium integrates available knowledge in algal biotechnology and ready to use reliable eco-friendly tools and methods for selecting and producing high yielding strains in economically feasible quantities and qualities. By cracking the biomass and supplying a wide diversity of chemical compounds for existing as well as new applications and markets, GENIALG will anticipate the economic, social and environmental impacts of such developments in term of economic benefit and job opportunities liable to increase the socio-economic value of the blue biotechnology sector. In a larger frame, conservation and biosafety issues will be addressed as well as more social aspects such as acceptability and competition for space and water regarding other maritime activities. To achieve these objectives GENIALG will foster a trans-sectorial and complementary consortium of scientists and private companies. GENIALG will involve a diversity of private companies already positioned in the seaweed sector individually for different applications (texturants, feed, agriculture, bioplastics, pharmaceuticals, personal care products) in order to strengthen interactions for developing a bio-refinery concept and accelerate efficient and sustainable exploitation of seaweed biomass to bring new high-value products on the market.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRAIA-01-2016-2017 | Award Amount: 10.01M | Year: 2017
Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europes nations. OPTICON has a proven record supporting European astrophysical excellence through development of new technologies, through training of new people, through delivering open access to the best infrastructures, and through strategic planning for future requirements in technology, innovative research methodologies, and trans-national coordination. Europes scientific excellence depends on continuing effort developing and supporting the distributed expertise across Europe - this is essential to develop and implement new technologies and ensure instrumentation and infrastructures remain cutting edge. Excellence depends on continuing effort to strengthen and broaden the community, through networking initiatives to include and then consolidate European communities with more limited science expertise. Excellence builds on training actions to qualify scientists from European communities which lack national access to state of the art research infrastructures to compete successfully for use of the best available facilities. Excellence depends on access programmes which enable all European scientists to access the best infrastructures needs-blind, purely on competitive merit. Global competitiveness and the future of the community require early planning of long-term sustainability, awareness of potentially disruptive technologies, and new approaches to the use of national-scale infrastructures under remote or robotic control. OPTICON will continue to promote this excellence, global competitiveness and long-term strategic planning.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: EINFRA-11-2016 | Award Amount: 16.11M | Year: 2017
PRACE, the Partnership for Advanced Computing is the permanent pan-European High Performance Computing service providing world-class systems for world-class science. Systems at the highest performance level (Tier-0) are deployed by Germany, France, Italy and Spain providing researchers with over 11 billion core hours of compute time. HPC experts from 25 member states enabled users from academia and industry to ascertain leadership and remain competitive in the Global Race. Currently PRACE is in transition to PRACE 2, the successor of the initial five year period. The objectives of PRACE-5IP are to build on and seamlessly continue the successes of PRACE and start new innovative and collaborative activities proposed by the consortium. These include: assisting the transition to PRACE 2 including an analysis of Trans National Access; strengthening the internationally recognised PRACE brand; continuing and extend advanced training which so far provided more than 18 800 persontraining days; preparing strategies and best practices towards Exascale computing; coordinating and enhancing the operation of the multi-tier HPC systems and services; and supporting users to exploit massively parallel systems and novel architectures. A high level Service Catalogue is provided. The proven project structure will be used to achieve each of the objectives in 6 dedicated work packages. The activities are designed to increase Europes research and innovation potential especially through: seamless and efficient Tier-0 services and a pan-European HPC ecosystem including national capabilities; promoting take-up by industry and new communities and special offers to SMEs; implementing a new flexible business model for PRACE 2; proposing strategies for deployment of leadership systems; collaborating with the ETP4HPC, CoEs and other European and international organisations on future architectures, training, application support and policies. This will be monitored through a set of KPIs.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: REV-INEQUAL-07-2016 | Award Amount: 5.00M | Year: 2017
IMAJINE aims to formulate new integrative policy mechanisms to enable European, national and regional government agencies to more effectively address territorial inequalities within the European Union. It responds to evidence that spatial inequalities within the EU are increasing, contrary to the principle of territorial cohesion embedded as a third dimension of the European Social Model in the Treaty of Lisbon, and is particularly timely in examining the geographically differentiated impacts of the post-2008 economic crisis and the adoption of austerity policies. IMAJINE uniquely proposes to address the problem of territorial inequalities through an inter-disciplinary and multi-scalar approach that integrates perspectives from economics, human geography, political science and sociology and combines macro-scale econometric analysis and the generation and analysis of new quantitative survey data with regionally-focused qualitative empirical case study research in 11 EU member states; delivered by a multi-disciplinary and multi-national consortium. As such the research builds on the conceptual and methodological state of the art in several disciplines and advances conceptual understanding and the empirical knowledge base by producing new primary data, applying new analytical tests to secondary data and integrating the results along with insights from relational geographical theory and the concept of spatial justice. In particular, the centrality of spatial justice emphasizes the political as well as economic dimensions of territorial inequalities, and IMAJINE will move beyond existing knowledge by considering relationships between measured and perceived inequalities, models of multi-level policy-making and public service delivery, and support for territorial autonomy movements. IMAJINE will further translate these scientific insights into policy applications through participatory scenario building exercises with governance and civil society stakeholders.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: ICT-15-2016-2017 | Award Amount: 18.70M | Year: 2017
Big Data will have a profound economic and societal impact in the mobility and logistics sector, which is one of the most-used industries in the world contributing to approximately 15% of GDP. Big Data is expected to lead to 500 billion USD in value worldwide in the form of time and fuel savings, and savings of 380 megatons CO2 in mobility and logistics. With freight transport activities projected to increase by 40% in 2030, transforming the current mobility and logistics processes to become significantly more efficient, will have a profound impact. A 10% efficiency improvement may lead to EU cost savings of 100 BEUR. Despite these promises, interestingly only 19 % of EU mobility and logistics companies employ Big Data solutions as part of value creation and business processes. The TransformingTransport project will demonstrate, in a realistic, measurable, and replicable way the transformations that Big Data will bring to the mobility and logistics market. To this end, TransformingTransport, validates the technical and economic viability of Big Data to reshape transport processes and services to significantly increase operational efficiency, deliver improved customer experience, and foster new business models. TransformingTransport will address seven pilot domains of major importance for the mobility and logistics sector in Europe: (1) Smart High-ways, (2) Sustainable Vehicle Fleets, (3) Proactive Rail Infrastructures, (4) Ports as Intelligent Logistics Hubs, (5) Efficient Air Transport, (6) Multi-modal Urban Mobility, (7) Dynamic Supply Chains. The TransformingTransport consortium combines knowledge and solutions of major European ICT and Big Data technology providers together with the competence and experience of key European industry players in the mobility and logistics domain.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 25.77M | Year: 2017
ACTIVAGE is a European Multi Centric Large Scale Pilot on Smart Living Environments. The main objective is to build the first European IoT ecosystem across 9 Deployment Sites (DS) in seven European countries, reusing and scaling up underlying open and proprietary IoT platforms, technologies and standards, and integrating new interfaces needed to provide interoperability across these heterogeneous platforms, that will enable the deployment and operation at large scale of Active & Healthy Ageing IoT based solutions and services, supporting and extending the independent living of older adults in their living environments, and responding to real needs of caregivers, service providers and public authorities. The project will deliver the ACTIVAGE IoT Ecosystem Suite (AIOTES), a set of Techniques, Tools and Methodologies for interoperability at different layers between heterogeneous IoT Platforms and an Open Framework for providing Semantic Interoperability of IoT Platforms for AHA, addressing trustworthiness, privacy, data protection and security. User-demand driven interoperable IoT-enabled Active & Healthy Ageing solutions will be deployed on top of the AIOTES in every DS, enhancing and scaling up existing services, for the promotion of independent living, the mitigation of frailty, and preservation of quality of life and autonomy. ACTIVAGE will assess the socio-economic impact, the benefits of IoT-based smart living environments in the quality of life and autonomy, and in the sustainability of the health and social care systems, demonstrating the seamless capacity of integration and interoperability of the IoT ecosystem, and validating new business, financial and organizational models for care delivery, ensuring the sustainability after the project end, and disseminating these results to a worldwide audience. The consortium comprises industries, research centres, SMEs, service providers, public authorities encompassing the whole value chain in every Deployment Site.
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ICT-17-2016-2017 | Award Amount: 4.94M | Year: 2017
The mission of BDVe is to support the Big Data Value PPP in realizing a vibrant data-driven EU economy or said in other words, BDVe will support the implementation of the PPP to be a SUCCESS. Behind that mission, there are multiple goals to achieve, which should be taken into full consideration when defining the directions of the PPP. Some of the most challenging ones are: (1) achieving a more competitive landscape of European Big Data providers, leading to bigger market share; (2) creating the context for a more competitive EU industry (transport, manufacturing, public sector, agrifood, media, energy) in the advent of a data-driven revolution where many traditional players will have to transform their processes and re-think their business if they want to remain completive or in some cases, just to survive-; (3) ensuring the sustainability of the investments and actions triggered by the PPP. BDVe has broken down those high-level goals into 7 major priorities for the project: Being accurately informed about most important facts in Big Data so that we have a solid basis to support the decision-making process in the PPP Supporting the implementation of the Big Data PPP from an operational point of view Developing a vibrant community around the PPP Supporting the development of a European network of infrastructures and centers of excellence around Big Data Setting-up a professional Communications strategy Setting up a framework that supports the acceleration of data-driven businesses, and Ensuring the sustainability of the investments and actions triggered by the PPP. The BDVe consortium includes a set of partners that have shown commitment and dedication to the success of the PPP for several years. They have already invested and they have committed to invest along the coming years. We believe that this CSA cannot be a neutral action that offers operational support without further commitment.
RESPINE - REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC1-PM-11-2016-2017 | Award Amount: 5.56M | Year: 2017
The World Health Organisation (WHO) has included low back pain in its list of twelve priority diseases. Notably, Degenerative disc disease (DDD) presents a large, unmet medical need which results in a disabling loss of mechanical function. Today, no efficient therapy is available. Chronic cases often receive surgery, which may lead to biomechanical problems and accelerated degeneration of adjacent segments. Our consortium partners have developed and studied stem cell-based, regenerative therapies with encouraging results in phase 1 and 2a trials. Patients exhibited rapid and progressive improvement of functional and pain indexes by 50% within 6 months and by 65% to 78% after 1 year with no side effects. In addition, MRI T2 relaxation measurements demonstrated a significant improvement. To develop the worlds first rigorously proven, effective treatment of DDD, RESPINE aims to assess, via a multicentre, randomized, controlled, phase 2b clinical trial including 112 patients with DDD, the efficacy of an allogenic intervertebral mesenchymal stem cell (MSC)-based therapy. This innovative therapy aims to rapidly (within 3 months) and sustainably (at least 24 months) reduce pain and disability. In addition, the consortium aims to provide new knowledge on immune response & safety associated with allogeneic BM-MSC intradiscal injection. This simple procedure would be cost-effective, minimally invasive, and standardised. The transfer to the clinic will be prepared at a cost below 10k thanks to the strategy of production of allogenic cells, automation & EU standardisation. At the end of the RESPINE trial, we aim to propose a broadly available and clinically applicable treatment for DDD, marketed by European SMEs.