Time filter

Source Type

Taitung City, Taiwan

Wang L.-C.,National Taitung Junior College | Wang L.-C.,Fu Jen Catholic University | Wang S.-E.,National Taitung University | Wang J.-J.,Fooyin University | And 4 more authors.
Applied Microbiology and Biotechnology

Antrodia camphorata is a particular and precious medicinal mushroom, and its fruiting body was found to provide more efficient protection from oxidative stress and inflammation than its mycelium because of its higher content of triterpenoids, total phenols, and so on. In the previous in vitro studies, the mycelium of A. camphorata is proven to provide strong neuroprotection in neuron cells and suggested to have the potential of protection against neurotoxicity of amyloid β-protein (Aβ) known as the risk factor toward Alzheimer's disease (AD) development. However, the in vivo study and the comparison study with the fruiting body have not yet been investigated. This study compared the effect of the fruiting body and mycelium of A. camphorata on alleviating the Aβ40-induced neurocytotoxicity in the in vitro Aβ-damaged neuron cell model (PC-12 cell treated with Aβ40) and memory impairment in the in vivo AD animal model induced with a continuous brain infusion of Aβ40. In the results of in vitro and in vivo studies, the fruiting body possessed stronger anti-oxidative and antiinflammatory abilities for inhibiting neurocytotoxicity in Aβ40-treated PC-12 cells and Aβ40 accumulation in Aβ40-infused brain than mycelium. Moreover, hyperphosphorylated tau (p-tau) protein expression, known as an important AD risk factor, was suppressed by the treatment of fruiting body rather than that of mycelium in the in vitro and in vivo studies. These comparisons supported the reasons why the fruiting body resulted in a more significant improvement effect on working memory ability than mycelium in the AD rats. © Springer-Verlag 2012. Source

Cheng T.C.,National Pingtung University of Science and Technology | Yao K.S.,National Taitung Junior College | Yeh N.,MingDao University | Chang C.I.,Taiwanese Fisheries Research Institute | And 2 more authors.
Thin Solid Films

This study uses blue LED light (λmax = 475 nm) activated TiO2/Fe3O4 particles to evaluate the particles' photocatalytic activity efficiency and bactericidal effects in seawater of variable salinities. Different TiO2 to Fe3O4 mole ratios have been synthesized using sol-gel method. The synthesized particles contain mainly anatase TiO2, Fe3O4 and FeTiO3. The study has identified TiO2/Fe 3O4's bactericidal effect to marine fish pathogen (Photobacterium damselae subsp. piscicida BCRC17065) in seawater. The SEM photo reveals the surface destruction in bacteria incubated with blue LED irradiated TiO2/Fe3O4. The result of this study indicates that 1) TiO2/Fe3O4 acquires photocatalytic activities in both the freshwater and the seawater via blue LED irradiation, 2) higher photocatalytic activities appear in solutions of higher TiO 2/Fe3O4 mole ratio, and 3) photocatalytic activity decreases as salinity increases. These results suggest that the energy saving blue LED light is a feasible light source to activate TiO 2/Fe3O4 photocatalytic activities in both freshwater and seawater. Copyright © 2011 Published by Elsevier B.V. All rights reserved. Source

Li D.-C.,National Cheng Kung University | Chang F.M.,National Taitung Junior College | Chen K.-C.,United Microelectronics
Expert Systems with Applications

Early in the process of developing a new product, on hand data is usually scarce and it is hard to assess product reliability. Many previous studies thus assume prior product failure distribution in the area of reliability estimation. However, when real data distribution is different from the assumed one, the reliability estimation accuracy is biased. This paper proposed a modeling method with four steps to build a reliability growth model for new products without assuming prior distribution. A sequential test procedure and the Bayesian theorem are mainly employed in the method presented. The results indicate that the proposed method can successfully build a reliability growth model for new products. © 2009 Elsevier Ltd. All rights reserved. Source

Hsu C.-H.,National Taitung Junior College | Tsai W.-C.,Fo Guang University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)

As the promotion of cultural and creative industries has become a trend in the current economic development strategies of various countries, the global market has gradually moved its focus towards local styles, and creative design applications have become a global competitive advantage of an industry. Therefore, the main purpose of this study is to investigate the effectiveness evaluation index and design strategy on cultural and creative products of consumer cognition and preference. First, we undertook a preliminary survey by means of literature review and opinions from a group of experts, and selected representative product samples and evaluation indices. Afterward, we analyzed the results of the questionnaire survey and found that cultural and creative products have distinct identity for participants. Furthermore, the participants considered that the main attributes affecting the overall presentation of a product, in order of degree of influence were “material, product function, aesthetic image, design quality, appearance style”. © Springer International Publishing Switzerland 2015. Source

Chang Y.-P.,Fooyin University | Liu C.-H.,National Pingtung University of Science and Technology | Wu C.-C.,Chang Jung Christian University | Chiang C.-M.,National Taitung Junior College | And 2 more authors.
Fish and Shellfish Immunology

Zingerone, one of the active components of ginger, is a phenolic alkanone with antioxidant and anti-inflammatory properties. The effects of zingerone supplementation on the growth, immunity, and disease resistance of Pacific white shrimp (Litopenaeus vannamei) juveniles were studied. Four experimental diets, including a control diet (without zingerone enrichment) and 1, 2.5, and 5mg zingerone (kg diet) -1 were used. After 56 days of culture, shrimp fed diets supplemented with 1, 2.5, and 5mg zingerone (kg diet) -1 had significantly greater weight gain and feed efficiency than the controls. Furthermore, after 56 days of culture, shrimp fed all doses of the zingerone diet had higher survival rates compared to the controls after 24-72h of challenge by the pathogen, Vibrio alginolyticus. Significantly increased phenoloxidase levels were found in shrimp fed the zingerone diets at all doses, and respiratory bursts, lysozyme and phagocytic activities of shrimp fed 2.5 and 5mg zingerone (kg diet) -1 also significantly increased. Neither the total hemocyte count nor superoxide dismutase activity of the experimental and control groups revealed significant differences at any dose. The results indicate that zingerone can be recommended as a supplement to shrimp feed to increase growth, immunity, and disease resistance against the pathogen, V.alginolyticus. Use of zingerone as appetizer and immunostimulant in shrimp is promising. © 2011 Elsevier Ltd. Source

Discover hidden collaborations