Kaohsiung, Taiwan

National Sun Yat-sen University is a leading public research university located in Gushan District, Kaohsiung, Taiwan. It is considered as one of the most prestigious universities in Cross-Strait Economic Zone, 4th best ranked higher education institution in Taiwan, and one of 40 best universities under the age of 50 worldwide.Named after Dr. Sun Yat-sen, NSYSU was founded in 1980 as a re-established version of the original Sun Yat-sen University. This re-establishment has been made possible through the efforts of alumni of both the original Sun Yat-sen University and the historical Moscow Sun Yat-sen University.NSYSU comprises six colleges and is well known for its oceanography, cutting-edge technologies, business management, political science programs and strong ties with government officials. It presently receives funding from the "Aim for the Top University Project" of Taiwan’s Ministry of Education and is one of the four universities that make up Taiwan's Public Ivy, the Taiwan Comprehensive University System.The NSYSU campus is a natural fortress, it's surrounded on four sides by sea and mountain. Wikipedia.


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The present invention relates to a method for treating pain in a subject in need thereof, comprising administering an effective amount of a nucleic acid to the subject, wherein the nucleic acid comprises a PTEN nucleotide sequence of SEQ ID NO: 1. The present invention also provides a method for screening pharmaceutical compositions having an anti-pain effect, wherein the pharmaceutical compositions can stimulate the upregulation of PTEN.


Patent
National Sun Yat - sen University | Date: 2016-08-31

A method of producing a double-doped scintillation crystal is provided. Czochralski method is used to grow a double-doped single crystal boule. The double-doped single crystal boule is a single crystal boule of rare-earth silicate double-doped with cerium (Ce) and calcium (Ca) or magnesium (Mg). The double-doped single crystal boule is subjected to a thermal annealing process in a furnace. A yield of pixel samples of the double-doped scintillation crystal is improved after a processing process, and the present invention achieves low producing cost, high yield, less crystal fragmentations, high luminescence intensity and short decaying time.


Patent
National Sun Yat - sen University | Date: 2016-02-05

An adjustable aerodynamic lens system for aerodynamic focusing of aerosols comprises a hollow tube having an inlet terminal, an outlet terminal and a focusing segment located between the inlet terminal and the outlet terminal. The focusing segment includes a plurality of section tubes assembled in a manner to selectively focus aerosols of a specific average size. Each of the section tubes has a focusing orifice, and the diameters of the two adjacent focusing orifices are different. In specific, the section tubes having their focusing orifices of appropriate diameters are chosen according to the average size of aerosol particles to be focused, and assembled in sequence, so as to make aerosol fluid passing through to form a beam of aerosol particles with good focusing quality.


Patent
National Sun Yat - sen University | Date: 2017-02-22

An adjustable aerodynamic lens system for aerodynamic focusing of aerosols comprises a hollow tube having an inlet terminal, an outlet terminal and a focusing segment located between the inlet terminal and the outlet terminal. The focusing segment includes a plurality of section tubes assembled in a manner to selectively focus aerosols of a specific average size. Each of the section tubes has a focusing orifice, and the diameters of the two adjacent focusing orifices are different. In specific, the section tubes having their focusing orifices of appropriate diameters are chosen according to the average size of aerosol particles to be focused, and assembled in sequence, so as to make aerosol fluid passing through to form a beam of aerosol particles with good focusing quality.


A method for improving the oxygen-releasing ability of hemoglobin, hemoglobin variants, recombinant hemoglobin or hemoglobin-based blood substitutes to organs or peripheral tissues in human bodies is disclosed by administering a compound of phthalides to a subject in need thereof. The compound of phthalides is characterized by a phthalide functional group which is represented as Formula I, and forms at least one hydrogen bond with Arg141 of hemoglobin, hemoglobin variants, recombinant hemoglobin or hemoglobin-based blood substitutes, stabilizing the 1/2 interface of hemoglobin, further stabilizing the oxygenated hemoglobin, hemoglobin variants, recombinant hemoglobin or hemoglobin-based blood substitutes in the low oxygen affinity T state and facilitating the oxygen release to the organs or the peripheral tissues. A medication for improving the oxygen-releasing ability of hemoglobin, hemoglobin variants, recombinant hemoglobin, or hemoglobin-based blood substitutes to organs or peripheral tissues in human bodies is also disclosed.


Patent
Kaohsiung Medical University and National Sun Yat - sen University | Date: 2016-10-14

A bone nail apparatus includes a bone nail, a light source unit and a focalizing unit. The bone nail has a tube wall and at least one through hole. The tube wall is enclosed to form a receiving space. The at least one through hole extends through the tube wall and communicates with the receiving space. The light source unit includes a light emitter and at least one light transmission tube. The at least one light transmission tube is connected to the light emitter and receives a light therefrom. The at least one light transmission tube is received in the receiving space of the bone nail. Each light transmission tube has a light-outputting end aligned with a respective one of the at least one through hole. The focalizing unit has a light-receiving face facing one of the at least one through hole.


Patent
National Sun Yat - sen University | Date: 2016-12-29

A resistive random access memory includes a first electrode, a separating medium, a resistance changing layer and a second electrode. The first electrode has a mounting face. The separating medium has a first face in contact with the mounting face, a second face opposite to the first face, and an inner face extending between the first and second faces. The separating medium forms a through hole extending from the first to second face. A part of the mounting face is not covered by the separating medium. The separating medium has a first dielectric. The resistance changing layer extends along the part of the mounting face as well as the inner and second faces. The resistance changing layer has a second dielectric having a dielectric constant larger than a dielectric constant of the first dielectric by 2 or less. The second electrode is arranged on the resistance changing layer.


Patent
National University of Singapore, National Sun Yat - sen University, National Tsing Hua University and Northeastern University | Date: 2016-10-03

Transition metal dichalcogenide (TMD)-based spintronics devices, each including a TMD thin film layer, a first gate electrode, a first insulating layer sandwiched between the TMD thin film layer and the first gate electrode, a second gate electrode, and a second insulating layer sandwiched between the TMD thin film layer and the second gate electrode. Such a device, when also including a source electrode and a drain electrode, functions as a spin filter. On the other hand, when also including one source electrode and two drain electrode terminals, such a device functions as a spin separator. Also disclosed are methods of using the above-described TMD-based spintronics devices.


Patent
National Sun Yat - sen University and LandMark Optoelectronics Corporation | Date: 2016-05-04

An interference lithography device is provided with a laser source for providing a laser beam; a base thereon having a beam splitter for dividing the laser beam into a first beam portion and a second beam portion, a beam expander, a first set of reflectors, and a second set of reflectors; a set of lower reflectors; and a sample carrying stage for holding a substrate. The first beam portion and the second beam portion are respectively reflected from the second set of reflectors and then respectively reflected by the set of lower reflectors to form an interference pattern on the substrate.


Patent
National Sun Yat - sen University | Date: 2015-12-03

A resistive random access memory does not encounter the undesired effects caused by sneak current which occurs when a conventional resistive random access memory operates in an integrated circuit. The resistive random access memory includes a first electrode layer, a first insulating layer, an oxygen-containing layer, a second insulating layer and a second electrode layer. The first insulating layer is arranged on the first electrode layer. The oxygen-containing layer is arranged on the first insulating layer and includes an oxide doped with a metal element. The metal element does not exceed 10% of the oxygen-containing layer. The second insulating layer is arranged on the oxygen-containing layer, and the second electrode layer is arranged on the second insulating layer. In this arrangement, the undesired effects caused by sneak current can be effectively eliminated.

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