The National Research Council is the primary national research and technology organization of the Government of Canada, in science and technology research and development. The Minister of Industry is responsible for the National Research Council . The transformation of the NRC into an RTO that focuses on "business-led research" was part of the federal government's Economic Action Plan. On 7 May 2013, the NRC launched its new "business approach" in which it offered four business lines: strategic research and development, technical services, management of science and technology infrastructure and NRC-Industrial Research Assistance Program . With these services, NRC intends to shorten the gap between early stage research and development and commercialization. NRC now has over 30 approved programs. Wikipedia.
University of Basilicata and National Research Council Italy | Date: 2015-04-10
Diagnostic kit to diagnose Incontinentia Pigmenti (IP) (Pigment Incontinence) by means of which to make an analysis of a biological sample of a human organism to detect alterations in the nucleotide sequence of the IP locus. The diagnostic kit comprising primers for Real Time quantitative PCR analyses.
Agency: European Commission | Branch: H2020 | Program: ERA-NET-Cofund | Phase: SC5-02-2015 | Award Amount: 78.28M | Year: 2016
Within the European Research Area (ERA), the ERA4CS Consortium is aiming to boost, research for Climate Services (CS), including climate adaptation, mitigation and disaster risk management, allowing regions, cities and key economic sectors to develop opportunities and strengthen Europes leadership. CS are seen by this consortium as driven by user demands to provide knowledge to face impacts of climate variability and change, as well as guidance both to researchers and decisionmakers in policy and business. ERA4CS will focus on the development of a climate information translation layer bridging user communities and climate system sciences. It implies the development of tools, methods, standards and quality control for reliable, qualified and tailored information required by the various field actors for smart decisions. ERA4CS will boost the JPI Climate initiative by mobilizing more countries, within EU Member States and Associated Countries, by involving both the research performing organizations (RPOs) and the research funding organizations (RFOs), the distinct national climate services and the various disciplines of academia, including Social Sciences and Humanities. ERA4CS will launch a joint transnational co-funded call, with over 16 countries and up to 75M, with two complementary topics: (i) a cash topic, supported by 12 RFOs, on co-development for user needs and action-oriented projects; (ii) an in-kind topic, supported by 28 RPOs, on institutional integration of the research components of national CS. Finally, ERA4CS additional activities will initiate a strong partnership between JPI Climate and others key European and international initiatives (as Copernicus, KIC-Climate, JPIs, WMO/GFCS, Future Earth, Belmont Forum) in order to work towards a common vision and a multiyear implementation strategy, including better co-alignment of national programs and activities up to 2020 and beyond.
Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016
Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses ICT to integrate neuroscience data from around the world, to develop a unified multi-level understanding of the brain and diseases, and ultimately to emulate its computational capabilities. The goal is to catalyze a global collaborative effort. During the HBPs first Specific Grant Agreement (SGA1), the HBP Core Project will outline the basis for building and operating a tightly integrated Research Infrastructure, providing HBP researchers and the scientific Community with unique resources and capabilities. Partnering Projects will enable independent research groups to expand the capabilities of the HBP Platforms, in order to use them to address otherwise intractable problems in neuroscience, computing and medicine in the future. In addition, collaborations with other national, European and international initiatives will create synergies, maximizing returns on research investment. SGA1 covers the detailed steps that will be taken to move the HBP closer to achieving its ambitious Flagship Objectives.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: PILOTS-02-2016 | Award Amount: 9.44M | Year: 2017
PROTECT aims to introduce to the market One step antimicrobial finish processes for polymeric materials used in i) specialty textiles for public areas and hospitals, ii) water treatment membranes, and iii) implantable medical devices. Compared to main existing manufacturing routes, the proposed one-step coating technologies are simple, fast, and reproducible. For this, PROTECT uses as a starting point four existing pilot lines emanated from high successful FP7 projects SONO, NOVO and BioElectricSurface. PROTECT will upgrade the nanocoating One step process platform comprising: two roll to roll (R2R) pilots (sonochemical and spray coating) for functional textiles production, a R2R thermo-embedding pilot for antibacterial/biofilm preventing water treatment membranes, and a batch sonochemical pilot for antibacterial/antibiofilm/biocompatible medical devices. This platform will cover a wide range of applications due to their specific characteristics by the following objectives: a) Incorporating antibacterial antibiofilm biocompatible novel nanoparticles(NPs) of the following categories: inorganic (CuxZn1-xO ,5 Ga@C-dots, Si/TiO2 composite) polymer (polypyrrole, PPy)) and biologicals (antibacterial enzymes, functionalized lipids (FSLs), hybrid antibacterials) to obtain biocompatible nanostructured surfaces with antimicrobial and anti-adhesive properties. b) Implementing real time characterization methods for monitoring at the nanoscale to characterise relevant materials, process properties and product features for real-time nanoscale characterization to ensure reproducibility and quality of the nano-coated products c) Improving coating efficiency, production capacity, reproducibility, robustness, cost-effectiveness, safety and sustainability of the processes in relation to the targeted applications. d) Introducing a Labs Network (PLN) that will include also lab scale processes of the proposed technologies for training and knowledge dissemination.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC1-PM-04-2016 | Award Amount: 7.35M | Year: 2017
Over 130,000 children born in Europe every year will have a congenital anomaly (CA; birth defect). These CAs, which are often rare diseases, are a major cause of infant mortality, childhood morbidity and long-term disability. EUROCAT is an established European network of population-based registries for the epidemiologic surveillance of CAs. EUROlinkCAT will use the EUROCAT infrastructure to support 21 EUROCAT registries in 13 European countries to link their CA data to mortality, hospital discharge, prescription and educational databases. Each registry will send standard aggregate tables and analysis results to a Central Results Repository (CRR) thus respecting data security issues surrounding sensitive data. The CRR will contain standardised summary data and analyses on an estimated 200,000 children with a CA born from 1995 to 2014 up to age 10, enabling hypotheses on their health and education to be investigated at an EU level. This enhanced information will allow optimisation of personalised care and treatment decisions for children with rare CAs. Registries will be supported in using social media platforms to connect with families who live with CAs in their regions. A novel sustainable e-forum, ConnectEpeople, will link these families with local, national and international registries and information resources. ConnectEpeople will involve these families in setting research priorities and ensuring a meaningful dissemination of results. Findings will provide evidence to inform national treatment guidelines, such as concerning screening programs, to optimise diagnosis, prevention and treatment for these children and reduce health inequalities in Europe. An economic evaluation of the hospitalisation costs associated with CA will be provided. The CRR and associated documentation, including linkage and standardisation procedures and ConnectEpeople forum will be available post-EUROlinkCAT thus facilitating future local and EU level analyses.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: NMBP-10-2016 | Award Amount: 6.09M | Year: 2017
The incidence of Cardiovascular Disease (CD) claims worldwide 17.1 million lives a year, with an estimated 31% of all deaths globally and a EU cost of 139 billion euros. Up to 40% of all deaths occur among the elderly. In spite of all medical efforts, the 5-year mortality was reduced significantly less than that of malignant diseases. This highlights the urgent need to overcome the difficulties associated with present pharmacological therapies (i.e. drug instability, and unspecific targeting) by developing new ground-breaking therapeutic strategies that go far beyond any current regimens. New approaches for safe, efficient, and heart-specific delivery of therapeutics are strongly required. CUPIDO is envisioned to meet these critical needs by providing an unconventional and effective strategy based on nanoparticle-assisted delivery of clinically available and novel therapeutics to the diseased heart. In particular, CUPIDO will develop innovative bioinspired hybrid nanoparticles formulated as biologicals delivery, which are i) biocompatible and biodegradable, ii) designed for crossing biological barriers, and iii) guidable to the heart. A combination of multidisciplinary manufacturing and validation approaches will be employed, bringing the envisioned product beyond the currently available clinical and day-to-day management of CD individuals. Scale-up production, and respect of medical regulatory requirements will allow CUPIDO to deliver a final product for future late pre-clinical and clinical studies. Altogether, CUPIDO will foster the translation of nanomedical applications toward the cardiac field, which although still in its start, offers great potential to overcome the limitations associated to the currently pharmacological treatments.
Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016
This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the following parts are implemented as Core Projects under the Horizon 2020 framework. The mission of the Graphene Flagship is to take graphene and related layered materials from a state of raw potential to a point where they can revolutionise multiple industries. This will bring a new dimension to future technology a faster, thinner, stronger, flexible, and broadband revolution. Our program will put Europe firmly at the heart of the process, with a manifold return on the EU investment, both in terms of technological innovation and economic growth. To realise this vision, we have brought together a larger European consortium with about 150 partners in 23 countries. The partners represent academia, research institutes and industries, which work closely together in 15 technical work packages and five supporting work packages covering the entire value chain from materials to components and systems. As time progresses, the centre of gravity of the Flagship moves towards applications, which is reflected in the increasing importance of the higher - system - levels of the value chain. In this first core project the main focus is on components and initial system level tasks. The first core project is divided into 4 divisions, which in turn comprise 3 to 5 work packages on related topics. A fifth, external division acts as a link to the parts of the Flagship that are funded by the member states and associated countries, or by other funding sources. This creates a collaborative framework for the entire Flagship.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: INFRADEV-04-2016 | Award Amount: 9.95M | Year: 2017
The EOSCpilot project will support the first phase in the development of the European Open Science Cloud (EOSC) as described in the EC Communication on European Cloud Initiatives . It will establish the governance framework for the EOSC and contribute to the development of European open science policy and best practice; It will develop a number of pilots that integrate services and infrastructures to demonstrate interoperability in a number of scientific domains; and It will engage with a broad range of stakeholders, crossing borders and communities, to build the trust and skills required for adoption of an open approach to scientific research . These actions will build on and leverage already available resources and capabilities from research infrastructure and e-infrastructure organisations to maximise their use across the research community. The EOSCpilot project will address some of the key reasons why European research is not yet fully tapping into the potential of data. In particular, it will: reduce fragmentation between data infrastructures by working across scientific and economic domains, countries and governance models, and improve interoperability between data infrastructures by demonstrating how data and resources can be shared even when they are large and complex and in varied formats, In this way, the EOSC pilot project will improve the ability to reuse data resources and provide an important step towards building a dependable open-data research environment where data from publicly funded research is always open and there are clear incentives and rewards for the sharing of data and resources.
Agency: European Commission | Branch: H2020 | Program: IA | Phase: IoT-01-2016 | Award Amount: 25.77M | Year: 2017
ACTIVAGE is a European Multi Centric Large Scale Pilot on Smart Living Environments. The main objective is to build the first European IoT ecosystem across 9 Deployment Sites (DS) in seven European countries, reusing and scaling up underlying open and proprietary IoT platforms, technologies and standards, and integrating new interfaces needed to provide interoperability across these heterogeneous platforms, that will enable the deployment and operation at large scale of Active & Healthy Ageing IoT based solutions and services, supporting and extending the independent living of older adults in their living environments, and responding to real needs of caregivers, service providers and public authorities. The project will deliver the ACTIVAGE IoT Ecosystem Suite (AIOTES), a set of Techniques, Tools and Methodologies for interoperability at different layers between heterogeneous IoT Platforms and an Open Framework for providing Semantic Interoperability of IoT Platforms for AHA, addressing trustworthiness, privacy, data protection and security. User-demand driven interoperable IoT-enabled Active & Healthy Ageing solutions will be deployed on top of the AIOTES in every DS, enhancing and scaling up existing services, for the promotion of independent living, the mitigation of frailty, and preservation of quality of life and autonomy. ACTIVAGE will assess the socio-economic impact, the benefits of IoT-based smart living environments in the quality of life and autonomy, and in the sustainability of the health and social care systems, demonstrating the seamless capacity of integration and interoperability of the IoT ecosystem, and validating new business, financial and organizational models for care delivery, ensuring the sustainability after the project end, and disseminating these results to a worldwide audience. The consortium comprises industries, research centres, SMEs, service providers, public authorities encompassing the whole value chain in every Deployment Site.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: NMBP-02-2016 | Award Amount: 8.05M | Year: 2017
Silicon carbide presents a high breakdown field (2-4 MV/cm) and a high energy band gap (2.33.2 eV), largely higher than for silicon. Within this frame, the cubic polytype of SiC (3C-SiC) is the only one that can be grown on a host substrate with the huge opportunity to grow only the silicon carbide thickness required for the targeted application. The possible growth on silicon substrate has remained for long period a real advantage in terms of scalability regarding the reduced diameter of hexagonal SiC wafer commercially available. Even the relatively narrow band-gap of 3C-SiC (2.3eV), which is often regarded as detrimental in comparison with other polytypes, can in fact be an advantage. The lowering of the conduction band minimum brings about a reduced density of states at the SiO2/3C-SiC interface and MOSFET on 3C-SiC has demonstrated the highest channel mobility of above 300 cm2/(Vxs) ever achieved on SiC crystals, prompting a remarkable reduction in the power consumption of these power switching devices. The electrical activity of extended defects in 3C SiC is a major concern for electronic device functioning. To achieve viable commercial yields the mechanisms of defects must be understood and methods for their reduction developed.. In this project new approaches for the reduction of defects will be used, working on new compliance substrates that can help to reduce the stress and the defect density at the same time. This growth process will be driven by numerical simulations of the growth and simulations of the stress reduction. The structure of the final devices will be simulated using the appropriated numerical tools where new numerical model will be introduced to take into account the properties of the new material. Thanks to these simulations tools and the new material with low defect density, several devices that can work at high power and with low power consumption will be realized inside the project.