National Research Council Italy

www.nrc-cnrc.gc.ca
Milan, Italy

The National Research Council is the primary national research and technology organization of the Government of Canada, in science and technology research and development. The Minister of Industry is responsible for the National Research Council . The transformation of the NRC into an RTO that focuses on "business-led research" was part of the federal government's Economic Action Plan. On 7 May 2013, the NRC launched its new "business approach" in which it offered four business lines: strategic research and development, technical services, management of science and technology infrastructure and NRC-Industrial Research Assistance Program . With these services, NRC intends to shorten the gap between early stage research and development and commercialization. NRC now has over 30 approved programs. Wikipedia.

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Patent
National Research Council Italy and University of Salento | Date: 2017-05-31

Method and related system for measuring physiological parameters of a human subject undergoing an olfactory stimulation comprising one or more smelling olfactory stimuli, where by means of said system and according to said method a human subject is undergone to said olfactory stimulation by sending said one or more smelling olfactory stimuli to the human subject; one or more physiological parameters of the human subject are recorded; and said olfactory stimulation and physiological parameters recording are synchronized.


Patent
National Research Council Italy and Catholic University of the Sacred Heart | Date: 2017-04-26

An injectable apatite cement, in which the calcium in the a phase is partially substituted with strontium, and in which tricalcium phosphate in the phase is also present is described. Also described is a method for its preparation and its use in bone regeneration, in particular in vertebroplasty, in kyphoplasty, and in pathologies characterized by a loss of bone substance.


Patent
Sciuto, National Research Council Italy and Fidia Farmaceutici S.p.A. | Date: 2017-06-07

The present invention relates to a derivative of carnosine (-alanyl-L-histidine) having formula (1), obtained by the functionalization of hyaluronic acid with carnosine.


Patent
National Research Council Italy and Humanitas Mirasole S.p.A. | Date: 2017-04-26

A process for the manufacture of a heart valve of polymer material which provides for the deposition of a polymer solution comprising a copolymer which is preferably a copolymer of poly(carbonato-urethane) fluoridate (F-PCU) and intracatenary polydimethylsiloxane (PDMS), a PDMS with a functional group outside the chain and a solvent onto a mould using a spray technique associated with phase inversion.


Patent
National Research Council Italy | Date: 2017-03-29

The invention relates to an in vitro or in vivo method for diagnosing Pagets disease or bone tumors associated therewith or for determining the predisposition of a subject affected by Pagets disease of bone to develop a bone tumor, the method being based on the detection of a mutation in the nucleotide sequence of the ZNF687 gene or in the amino acid sequence of the protein encoded by the mutated ZNF687 gene. The invention also refers to isolated nucleic acids comprising the mutated nucleotide sequence of the ZNF687 gene or a portion thereof and the encoded amino acid sequences.


Patent
L.E.S.S., Polyera Corporation and National Research Council Italy | Date: 2017-05-31

The present teachings relate to an organic electroluminescent transistor with improved light-emission characteristics. More specifically, the present organic electroluminescent transistor has an emissive ambipolar channel including at least one layer of an n-type semiconductor material, at least one layer of a p-type semiconductor material, and at least one layer of an emissive material arranged between the layers of the p-type and n-type semiconductor materials, where the multilayer emissive ambipolar channel includes, among various layers, a layer of a p-type semiconductor material comprising a benzothieno-benzothiophene compound, and/or a layer of an emissive material comprising a blend material that includes an organic carbazole derivative as the host matrix compound and an iridium complex as the guest emitter.


Patent
National Research Council Italy and University of Cagliari | Date: 2017-05-03

Method for regulating in real time the clock frequencies of at least one cluster of electronic machines, characterized in that it provides for carrying out the following steps: a) defining a finite number of discrete virtual capacity values f[1], f[2],.... f[K], as global performance indices, of said cluster of machines; b) calculating by means of a randomized optimization procedure, for each value of said virtual capacity, a set of 1 vectors containing clock frequency values for each machine in said cluster; c) defining a reference queue value, related to the number of processing requests received by said cluster; and provides for iteratively carrying out the following steps: d) measuring the deviation between a current queue value, related to the number of processing requests in said current queue, and said reference queue value; e) selecting one of said discrete virtual capacity values on the basis of said measured deviation, said selection occurring on the basis of a procedure that, at each iteration, analyzes said measured deviation, compares it with the measured deviation value obtained at the previous iteration, and chooses whether to keep the current virtual capacity value or to adopt one of the two adjacent or non-adjacent admissible virtual capacity values of said finite number of discrete values; f) selecting, based on said selected virtual capacity value, a vector of clock frequency values for each machine from said set of 1 vectors, so as to optimize a multi-target performance index (J), and then setting the clock frequency of each machine in the cluster.


Patent
IRBM Science Park S.p.A., Cnccs Scarl Collezione Nazionale Dei Composti Chimici E Centro Screening and National Research Council Italy | Date: 2017-05-24

The present invention relates to a Perhexiline compound of formula (I): or a pharmaceutically acceptable salt thereof, for use in the treatment of a pathology caused by trematodes.


Patent
National Research Council Italy and University of Salento | Date: 2017-01-23

Method and related system for measuring physiological parameters of a human subject undergoing an olfactory stimulation comprising one or more smelling olfactory stimuli, where by means of said system and according to said method a human subject is undergone to said olfactory stimulation by sending said one or more smelling olfactory stimuli to the human subject; one or more physiological parameters of the human subject are recorded; and said olfactory stimulation and physiological parameters recording are synchronized.


Patent
CSIC - Institute of Refrigeration and National Research Council Italy | Date: 2017-06-14

Process for obtaining fluoride-doped citrate-coated amorphous calcium phosphate nanoparticles. This material has applications in biomedicine due to its biodegradability and bioactivity; it also promotes cell adhesion and osteogeneration. In dentistry, it may be used in toothpastes, mouthwashes, chewing gums, gels and fluoride varnishes as a remineralising agent of dentine and enamel. It is based on two solutions formed by calcium chloride and sodium citrate on the one hand, and by sodium monohydrogenophosphate and sodium carbonate with a fluoride compound on the other, which are mixed at room temperature. The process is eco-efficient and eco-friendly, as it does not leave any acid residue; it consists of a single stage and it is the first time that an amorphous calcium phosphate coated with citrate and doped with fluoride, which enhances its remineralising action, is obtained.

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