Songpa gu, South Korea
Songpa gu, South Korea

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Lee J.H.,National Police Hospital | Lee S.W.,Sungkyunkwan University
Journal of Sexual Medicine | Year: 2015

Introduction: Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a common etiology of premature ejaculation (PE). However, the current data are insufficient to explain this relationship and to support routine screening of men with PE. Aims: This study aims to evaluate the relationship between PE and CP/CPPS. Methods: A cross-sectional study was conducted that included 8,261 men who had participated in a health examination. The Premature Ejaculation Diagnostic Tool (PEDT), the National Institutes of Health-Chronic Prostatitis Symptom Index (NIH-CPSI), and the International Index of Erectile Function-5 (IIEF) were used for assessment of symptoms. A full metabolic work-up and serum testosterone level checks were also performed. We then investigated the relationship using the Spearman correlation test, multiple linear regression, and logistic regression analyses. Main Outcome Measures: Associations of PEDT with NIH-CPSI. Results: The mean age was 50.4±5.5 years. In total, 2,205 (24.9%) men had prostatitis-like symptoms (NIH-CPSI pain score of ≥4 and perineal or ejaculatory pain), and 618 (7.0%) men had moderate to severe symptoms (NIH-CPSI pain score of ≥8). Additionally, 2,144 men (24.2%) were classified as demonstrating PE (PEDT>10). The PEDT score was found to have a significant positive correlation with the NIH-CPSI pain domain score (correlation coefficient=0.206; P<0.001). After adjusting for age, metabolic syndrome status, testosterone level, and IIEF score, there was no change in the positive correlation between the NIH-CPSI pain domain score and PEDT score (Beta=0.175; P<0.001). After adjusting for age, testosterone level, metabolic syndrome, and IIEF score, the odds ratio (OR) for PE significantly increased with the severity of pelvic pain (mild prostatitis-like symptoms, OR for PE: 1.269, 95% confidence interval: 1.113-1.447; moderate to severe symptoms, OR for PE: 2.134: 95% confidence interval: 1.782-2.557). Conclusions: Our data showed a significant correlation between the PEDT score and the NIH-CPSI score. We suggest routine screening for CP/CPPS in men with PE and PE in men with CP/CPPS. © 2014 International Society for Sexual Medicine.

Kim S.,Korea University | Lim J.,Seoul National University | Kye S.,National Police Hospital | Joung H.,Seoul National University
Diabetes Research and Clinical Practice | Year: 2012

Aims: Low serum 25-hydroxyvitamin D (25(OH)D) levels have been linked to metabolic syndrome. However, community-based data for healthy Korean individuals are lacking. We aimed to assess the vitamin D status and the association of 25(OH)D deficiency with metabolic syndrome in the South Korean population (latitude 33-38°N). Methods: In this population-based study, we assessed 5559 South Korean adults selected from the Korean National Health and Nutrition Examination Survey IV-2, 2008. We used multiple logistic regression analysis to assess the association between vitamin D deficiency and metabolic syndrome. Results: The prevalence of vitamin D deficiency (<20. ng/mL) was 56.0%. Subjects with vitamin D deficiency were younger and had higher education, lower physical activity, and lower alcohol consumption than those with normal vitamin D levels. The overall risk of metabolic syndrome was not associated with 25(OH)D concentration. The adjusted OR of reduced high density lipoprotein cholesterol (HDL-C) decreased across the quintiles of 25(OH)D concentrations (OR = 0.72; 95% confidence interval = 0.54-0.95 for comparisons of lowest vs. highest quintile; P for trend = 0.003). Conclusions: A high prevalence of vitamin D deficiency was noted in the general South Korean population. Serum 25(OH)D concentration was inversely associated with the risk of having reduced HDL-C. © 2012 Elsevier Ireland Ltd.

Noh J.H.,Kangwon National University | Roh Y.H.,Gachon University | Yang B.G.,National Police Hospital | Yi S.R.,National Police Hospital | Lee S.Y.,National Police Hospital
Arthroscopy - Journal of Arthroscopic and Related Surgery | Year: 2013

Purpose: The purpose of this study was to compare clinical outcomes after single-bundle anterior cruciate ligament (ACL) reconstruction with a free Achilles tendon allograft using either a transtibial or an anteromedial portal technique and then to quantify the difference in femoral tunnel position between these 2 approaches. This assessment was to be performed with a new method using conventional magnetic resonance imaging (MRI) with a digital imaging system. Methods: In this prospective randomized comparative study, 53 young male patients with ACL rupture underwent ACL reconstruction with the transtibial technique (group 1) or the anteromedial portal technique (group 2). We assessed clinical outcomes with the Lachman test, pivot shift test, International Knee Documentation Committee (IKDC) classification, Lysholm score, Tegner activity scale, and single leg hop (SLH) test. Radiologic assessments included the position of the femoral tunnel aperture and the posterior cruciate ligament (PCL) index on conventional MRI and the side-to-side difference (SSD) on stress radiographs. Results: Sixty-one participants had follow-up. The mean follow-up period was 30.2 months. At the last follow-up, there were no significant differences between the 2 groups in results from the Lachman test, pivot shift test, IKDC classification, Tegner activity scale, and SLH test. The Lysholm score and SSD results in group 2 were superior to those in group 1 (P <.001). The femoral tunnel aperture was positioned more posteriorly in group 2 than in group 1 (P <.001). Changes in the PCL index were greater in group 1 than in group 2 (P <.001). Conclusions: The position of the femoral tunnel aperture created with the anteromedial portal technique was more posterior than that made with the transtibial technique. Knees reconstructed with the anteromedial portal technique were more stable in Telos testing, and were 3 points higher on the Lysholm score. However, there were no statistically significant differences in the Tegner activity scale or IKDC classification between the 2 groups. Level of Evidence: Therapeutic level I, randomized controlled clinical trial. © 2013 by the Arthroscopy Association of North America.

Atkinson R.L.,Obetech Obesity Research Center | Lee I.,National Police Hospital | Shin H.-J.,National Medical Center | He J.,Obetech Obesity Research Center
International Journal of Pediatric Obesity | Year: 2010

Background. Human adenovirus-36 (Ad-36) is thought to induce obesity by a direct effect of the viral E4orf1 gene on lipogenic enzymes in host adipocytes. Ad-36 prevalence is 30% in obese adults, but prevalence has not been reported in childhood obesity. Objectives. To determine the prevalence of Ad-36 infection in obese Korean children (age 14.8 ± 1.9; range 8.36.3 years); correlation of infection with BMI z-score and other obesity measures. Methods. Blood was drawn at the annual school physical exam or clinic visit; Ad-36 status was determined by serum neutralization assay; and routine serum chemistry values. Results. A total of 30% of subjects were positive (N 25) for Ad-36; 70% were negative (N 59). Significantly higher BMI z-scores (1.92 vs. 1.65, p < 0.01) and waist circumferences (96.3 vs. 90.7 cm, p=0.05) were found in infected versus uninfected children. Cardiovascular risk factors were not significantly different. Conclusions. Ad-36 infection is common in obese Korean children and correlates highly with obesity. Ad-36 may have played a role in the obesity and Type 2 diabetes epidemic in children. © 2010 Informa UK Ltd.

Objective To evaluate which among the lower urinary tract symptom (LUTS)/benign prostatic hyperplasia (BPH) measures is the most relevant to erectile dysfunction (ED) and elucidate the role of metabolic syndrome (MetS) and testosterone in their relationship. Methods A total of 2564 policemen aged 40-59 years who had participated in a health examination were included. LUTS/BPH and ED were evaluated by the international prostate symptoms score (IPSS), transrectal ultrasonography, uroflowmetry, postvoid residual urine volume (PVR), and international index of erectile function questionnaire 5 (IIEF-5). Spearman correlation tests, multiple linear regression tests, and logistic regression analyses were used. Results The median age was 49.0 years; the median total IPSS and IIEF scores were 9 and 19, respectively. Among the LUTS/BPH measures, IPSS (r = -0.311, P <.001) showed the highest correlation coefficient with IIEF, followed by total prostate volume (r = -0.082, P <.001), PVR (r = -0.080, P <.001), and maximal flow rate (r = 0.049, P =.014). In addition, only IPSS was significantly correlated with the IIEF score after adjusting for age, testosterone, and MetS. The severity of LUTS, as assessed by IPSS, was also significantly correlated with moderate to severe ED (IIEF ≤11), after adjusting for age, testosterone, MetS, and other LUTS/BPH measures. On multiple linear regression test, adjustment of Mets changed the P value and beta value of LUTS/BPH measures. However, there were no changes after adjusting testosterone. Conclusion IPSS is the most powerful predictor of ED among the LUTS/BPH measures in middle-aged policemen. In addition, MetS might be a plausible explanation for the relationship between LUTS/BPH and ED. © 2013 Elsevier Inc.

Kwon H.,Yonsei University | Kang H.C.,Yonsei University | Lee J.H.,National Police Hospital | Lee J.H.,Yonsei University
Urology | Year: 2013

Objective: To investigate the association between the metabolic syndrome (MetS) and the predictors of the progression of benign prostatic hyperplasia (BPH). Materials and Methods: A total of 778 male police officers in their 50s with moderate to severe lower urinary tract symptoms (International Prostate Symptom Score > 7) were included in the present study. We defined the predictors of the risk of clinical progression of BPH as the total prostate volume ≥31 cm3, prostate-specific antigen level ≥1.6 ng/mL, maximal flow rate <10.6 mL/s, and postvoid residual urine volume of ≥39 mL. The MetS was defined using the National Cholesterol Education Program-Adult Treatment Panel III guidelines. We used the Mantel-Haenszel extension test and logistic regression analyses to statistically examine their relationship. Results: The percentage of participants with ≥1 predictor for the progression of BPH, the percentage of participants with a total prostate volume of ≥31 cm3, and the percentage of participants with a postvoid residual urine volume of ≥39 mL increased significantly with the increase in the number of components of the MetS (P =.003, P =.001, and P =.007, respectively). After adjusting for age and serum testosterone levels, the MetS was shown to be significantly associated with the presence ≥1 predictor for the progression of BPH (odds ratio 1.423, 95% confidence interval 1.020-1.986). Conclusion: Our data have shown that the MetS is associated with the predictors of the risk of clinical progression of BPH in men in their 50s with moderate to severe lower urinary tract symptoms. © 2013 Elsevier Inc. All Rights Reserved.

Introduction: There is controversy concerning the relationship between premature ejaculation (PE) and erectile dysfunction (ED), as well as the scan data regarding the association between PE and lower urinary tract symptoms (LUTS). Aims: We performed this study to evaluate the association between PE and ED or LUTS. Methods: A total of 2,591 policemen aged 40-59 years who had participated in a health examination were included in this study. PE, LUTS, and ED were evaluated using the premature ejaculatory diagnostic tool (PEDT), the International Prostate Symptoms Score (IPSS), and the International Index of Erectile Function questionnaire-5 (IIEF), respectively. Spearman's correlation test, the multiple linear regression test, and logistic regression analyses were used to evaluate the relationship between PE and ED or LUTS. Main Outcome Measures: Associations between PEDT, IPSS, and IIEF. Results: The middle age of the study group was 49.1 years, and the middle PEDT, IIEF, and IPSS was 7.5, 17.0, and 10.7, respectively. By univariate analysis, PEDT showed a significant correlation with IPSS (r=0.310, P<0.001) and IIEF (r=-0.413, P<0.001). After adjusting for age, components of metabolic syndrome, testosterone, and IIEF, PEDT was significantly correlated with IPSS (Beta=0.166, P<0.001). PEDT was also significantly correlated with IIEF after adjusting for age, components of metabolic syndrome, testosterone, and IPSS (Beta=-0.274, P<0.001). Additionally, the severity of LUTS or ED was associated with the PE positive ratio (P trend<0.001). The odds ratio (OR) for PE also increased with the severity of LUTS or ED after adjusting for potential confounding factors. Conclusions: ED and LUTS were significantly and independently correlated with PE. Lee JH. Associations between premature ejaculation, lower urinary tract symptoms, and erectile dysfunction in middle-aged Korean policemen. J Sex Med 2014;11:1512-1518. © 2014 International Society for Sexual Medicine.

Cho J.E.,National Police Hospital
Ophthalmic Plastic and Reconstructive Surgery | Year: 2016

The authors report a case of fungus ball of the maxillary sinus with bone erosion presenting with epiphora, which was diagnosed after treatment failure using silicone intubation for nasolacrimal duct obstruction. Symptoms of sinus fungus ball are similar to those of chronic bacterial rhinosinusitis, although occasionally asymptomatic. To our knowledge, epiphora has never been reported as a symptom of sinus fungus ball. The purpose of this report is to emphasize the importance of considering sinonasal causes when evaluating epiphora patients, as well as to suggest the use of preoperative CT scans for a more accurate diagnosis and to prevent unnecessary procedures. © 2016 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.

Purpose: There is a lack of information on female urinary incontinence (UI) in South Korea. We investigated the prevalence, risk factors, quality of life (QoL), and healthcare-seeking behaviors of women with UI. Methods: We included 9,873 women over the age of 20 years who had participated in the Korea National Health and Nutrition Examination Survey IV. The condition of UI was defined as answering "yes" to the question "Do you have UI?" Additionally, health care seeking behavior for UI was defined as answering "yes" to "Have you ever been treated for UI?" The EuroQoL-5 Dimension (EQ-5D) descriptive system was used to evaluate QoL. Results: The mean age of our sample was 49.7 years. The overall prevalence of UI was 7.9%. The prevalence of UI significantly increased with age. The rate of healthcare-seeking behavior for UI also significantly increased with age. However, the rate of healthcare seeking for UI was significantly lower when compared to the prevalence of UI. In our multivariate analysis, age, body mass index, and marriage were significantly and independently associated with UI. As the severity of all the subscales of EQ-5D increased, the unadjusted odds ratio for UI also increased. After adjusting for potential confounders, the subscales of mobility, usual activities, pain/discomfort, and anxiety/depression from the EQ-5D were significantly associated with UI. Conclusions: UI is a common disease and is significantly associated with QoL. Our results suggest the need for developing preventive measures and treatment policies for UI. © 2014 Korean Continence Society.

Park Y.W.,National Police Hospital | Lee J.H.,National Police Hospital
International Neurourology Journal | Year: 2014

Purpose: To evaluate the correlation between the Visual Prostate Symptom Score (VPSS) and International Prostate Symptom Score (IPSS). Methods: We enrolled 240 new male patients who had visited National Police Hospital more than twice during a 6-month period starting from July 2013. At initial visit, the Korean version of the IPSS and VPSS, uroflowmetry, and transrectal ultrasonography were used to evaluate urinary symptoms. After medication, IPSS and VPSS questionnaires were issued again. The Spearman correlation test and the Mantel-Haenszel test were used to evaluate the relationship between the IPSS and VPSS. Results: The median age, total prostate volume, total IPSS, and total VPSS were 59.0 years, 28.0 mL, 12, and 9, respectively. Total VPSS, VPSS obstructive symptoms, VPSS irritative symptoms, and VPSS quality of life (QoL) significantly correlated with the total IPSS, IPSS obstructive symptoms, IPSS irritative symptoms, and IPSS QoL, respectively (correlation coefficient, P-value: 0.632, <0.001; 0.431, <0.001; 0.696, <0.001; and 0.799, <0.001; respectively). The change in the total IPSS after treatment also significantly correlated with the change in total VPSS after treatment (correlation coefficient, P-value: 0.364, <0.001). There were significant correlations between maximal flow rate and IPSS/VPSS obstructive symptoms (correlation coefficient, P-value: -0.190, 0.004; -0.269, <0.001, respectively). Additionally, there was a significant increase in the ratio of the maximal flow rate <15 mL/sec to VPSS obstructive symptoms as the severity of the VPSS obstructive symptoms increased (P trend <0.001). Conclusions: VPSS might be useful in evaluating lower urinary tract symptoms at the initial visit and assessing these symptoms at longitudinal follow-up examinations. © 2014 Korean Continence Society.

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