Insa National Institute Of Health Dr Ricardo Jorge

Porto, Portugal

Insa National Institute Of Health Dr Ricardo Jorge

Porto, Portugal
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Richter J.,Heinrich Heine University Düsseldorf | Botelho M.C.,Insa National Institute Of Health Dr Ricardo Jorge | Holtfreter M.C.,Heinrich Heine University Düsseldorf | Akpata R.,Hopital Saint Jean de Dieu | And 6 more authors.
Zeitschrift fur Gastroenterologie | Year: 2016

In 2000, the World Health Organization (WHO) issued an ultrasound field protocol for assessing the morbidity due to Schistosoma (S.) haematobium and S. mansoni. The experience with this classification has recently been reviewed systematically. The WHO protocol was well accepted worldwide. Here we review the use of ultrasound to assess the morbidity due to schistosomiasis with emphasis on easy, quick, and reproducible ways that can be used in the field. Findings obtained with high-end ultrasound scanners in the hospital setting that might eventually have applications in the field are also described. © Georg Thieme Verlag KG Stuttgart, New York.


PubMed | Insa National Institute Of Health Dr Ricardo Jorge and Heinrich Heine University Düsseldorf
Type: Letter | Journal: Parasitology research | Year: 2016

Infection with the human liver fluke Opisthorchis viverrini induces cancer of the bile ducts, cholangiocarcinoma (CCA). It was shown previously that O. viverrini-secreted proteins accelerate wound resolution in human cholangiocytes. Recombinant Ov-GRN-1 (O. viverrini-derived gene encoding granulin-like growth factor) induced angiogenesis and accelerated mouse wound healing. Given the striking similarities of wound healing and cancer progression, here we discuss the major implications of this finding for an infection-induced cancer of major public health significance in the developing world.

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