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Bottausci F.,CEA Grenoble | Baleras F.,CEA Grenoble | Pudda C.,CEA Grenoble | Cochet M.,CEA Grenoble | And 10 more authors.
International IEEE/EMBS Conference on Neural Engineering, NER | Year: 2015

This paper describes the fabrication and the packaging of a flexible parylene-based multi-contact electrode embedded in a silicone-based cuff. This type of electrode is well suited for peripheral nerve recording and offers improved spatial selectivity. We conducted mechanical and electrical tests for assessing the reliability by using an accelerated lifetime protocol. Test structures made with platinum sandwiched with parylene C were designed. The accelerated lifetime soaking tests in phosphate buffered saline (PBS) solution at 67°C showed a longer life time (approximatively 4.5 years) with a dehydration bake introduction in the process flow and a parylene thickness increase. A specific test bench was developed for the mechanical cycling and for evaluating the mechanical robustness of the thin film devices. © 2015 IEEE. Source

Malbert C.-H.,Institute National of Agronomic Research | Divoux J.-L.,Axonic | Maciejasz P.,Axonic | Picq C.,Axonic | And 2 more authors.
International IEEE/EMBS Conference on Neural Engineering, NER | Year: 2015

The voltage required to stimulate small diameter myelinated (Adelta fibres) and unmyelinated (C fibres) neurons consistently is so large that it is unsafe for chronic vagal stimulation. We present here a solution that reduces by 80% the amount of electrical charge necessary to produce action potential. These solutions were tested in a porcine model that allowed simultaneously to locate the origin of the afferent neurons, to stimulate the vagal trunks at distance from the recording electrode and to record the evoked activity of one neuron using the single afferent method. The reduction in current supplied by the most effective pulse pattern makes possible to incorporate this solution in an implanted device without damaging the vagal nerve. © 2015 IEEE. Source

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