National Institute for Chemical Pharmaceutical RandD ICCF Bucharest

Bucharest, Romania

National Institute for Chemical Pharmaceutical RandD ICCF Bucharest

Bucharest, Romania
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Grigore A.,National Institute for Chemical Pharmaceutical RandD ICCF Bucharest | Colceru-Mihul S.,National Institute for Chemical Pharmaceutical RandD ICCF Bucharest | Paraschiv I.,National Institute for Chemical Pharmaceutical RandD ICCF Bucharest | Nita S.,National Institute for Chemical Pharmaceutical RandD ICCF Bucharest | And 3 more authors.
Romanian Biotechnological Letters | Year: 2012

Phytochemical and antimicrobial screenings of 5 volatile oils of plants (Thymus vulgaris L, Salvia officinalis L, Foeniculum vulgare L., Achillea millefolium L., Carum carvi L.) growing in Southeastern Romanian area were performed. Specific compounds for each species were detected by GC: anethol (80.89% in Foeniculi fructus), carvone (17.37% in Carvi fructus), β-thujone and camphor (30.88% and respectively 21.73% in Salviae herba), thymol (30.86% in Thymi herba) but also other compounds like 1,8-cineol (15.59% in Millefolii flores and 8.55% in Salviae herba), p-cymene (30.53% in Thymi herba and respectively 24.24% in Carvi fructus), borneol (25.79% in Millefolii flores), etc. In vitro antimicrobial activities of volatile oils were tested using two methods: the dilution method for determination of minimal inhibitory concentration and the cylinder-plate diffusion method. All volatile oils showed different levels of inhibitory activity against microbial strains tested. Thymus vulgaris volatile oil was the most active.

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