Kuala Selangor, Malaysia
Kuala Selangor, Malaysia

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Wan Mohd Zin R.M.,Institute for Medical Research | Ahmad Kamil Z.I.,Institute for Medical Research | Tuan Soh T.R.,Institute for Medical Research | Embong M.,Universiti Sains Malaysia | And 2 more authors.
BMC Research Notes | Year: 2013

Background: Measurement of HbA1c has been widely used for long-term monitoring and management of diabetes control. There is increasing use of point-of-care (POC) devices for measuring HbA1c where quicker results would allow immediate clinical management decisions to be made. Therefore, it is important to evaluate and compare the performance of such devices to the reference laboratory method. Findings. A total of 274 venous blood was collected from normal healthy adults during the community screening programmes. The performance of POC devices, Afinion and Quo-test were compared to central laboratory HPLC method; Adams A1c HA 8160. Both POC devices showed good correlation to HA 8160 with r = 0.94 (p < 0.001) and r = 0.95 (p < 0.001) for Afinion and Quo-test respectively. The means difference were statistically higher between POC and HA 8160 with 0.23% (95% CI 0.19-0.26, p < 0.001) and 0.29% (95% CI 0.24-0.34, p < 0.001) for Afinion and Quo-test respectively. Conclusions: Both POC devices could be considered in health clinics for diabetes management but not to be used for the diagnostic purposes. © 2013 Wan Mohd Zin et al.; licensee BioMed Central Ltd.

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