Tainan, Taiwan

National Cheng Kung University is a research-led comprehensive university in Tainan City, Taiwan. In Chinese, its name is shortened to 成大 . Cheng Kung is named after Cheng Ch'eng-Kung , who defeated the Dutch and founded the Kingdom of Tungning in Taiwan. NCKU is one of the most prestigious universities in Taiwan, with a high reputation in science, engineering, medicine, management, planning and design. According to US News and World Report - 2014 Global Universities Ranking , NCKU was ranked #22 Best Global University for Engineering and Computer Science. Times Higher Education- QS World University Rankings and Performance Ranking of Scientific Papers for World Universities, NCKU was ranked second or third among all universities in Taiwan. Many surveys throughout the years have shown that its students are most desired by Taiwanese companies. NCKU has 9 colleges, 40 departments, 82 graduate institutes, and 54 research centers, and it is also a major university, educational, and area-network center in Taiwan.NCKU is among the four universities of Taiwan's Public Ivy - the Taiwan Comprehensive University System. Wikipedia.

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Patent
National Cheng Kung University | Date: 2017-02-08

Reducing inflammatory pain in a subject having or being suspected of having an inflammatory pain using an IL-20 antagonist, which can be an antibody that blocks a signaling pathway mediated by IL-20. Such antibodies include anti-IL-20 antibodies and anti-IL-20R antibodies that specifically block the IL-20 signaling pathway.


Patent
National Cheng Kung University | Date: 2016-08-22

The present invention relates to a biodegradable nanocomplex. The biodegradable nanocomplex comprises a first electrically charged substance, a charge-redistribution substance, a second electrically charged substance and a carried substance, for holding the carried substance inside. The first electrically charged substance and the carried substance have the same electrical polarity, and the biodegradable nanocomplex has a nonuniformally and positively charge distribution along a radial direction thereof. The nonuniformally and positively charge distribution comprises a first electrically charged portion having substantially electrical neutrality, a second electrically charged portion surrounding the first electrically charged portion, and a third electrically charged portion surrounding the second electrically charged portion, in which the third electrically charged portion comprises an outermost surface of the biodegradable nanocomplex, thereby modulating the carried substance towards the desired immune responses via the nonuniformally and positively charge distribution.


Patent
National Cheng Kung University | Date: 2016-09-23

A method for determining a treatment response of cells is provided with steps of providing a un-treated first sample and a treated second sample; applying an electric signal to the first sample and the second sample; obtaining a first motion parameter of the first sample and a second motion parameter of the second sample in the electric signal, respectively; and comparing the first motion parameter and the second motion parameter to determine whether there is a difference. The difference represents that the treatment response exists.


Patent
National Cheng Kung University | Date: 2016-05-20

A limb movement function evaluating method and the implantation system are provided. The aforementioned system includes a limb fixing device, limb guiding device, driver, actuator, impedance detector, and movement function analyzer. The limb fixing device is used to fix the first end of the user limb. The driver is used to guide the second end of the user limb through the actuator so as to make the second end moving relatively to the first end. The impedance detector is further connected to the driver so as to measure mechanical impedance where the movement of the user limb responses to the driving point of the driver. Finally, the limb movement analyzer compares the measured mechanical impedance and the movement path of the user limb so as to form a limb movement function curve. Therefore, the medical staff can make accurate rehabilitation evaluation according to the limb movement function curve.


Patent
National Cheng Kung University | Date: 2017-06-28

Disintegrin variants that bind specifically to one or more of 51 and v integrins, such as 1, 3, 5, 6 and 8, but with reduced binding activity to IIb3, are described. Also described are uses of the disintegrin variants for the treatment or prevention of a disease associated with an v integrin or an 51 integrin.


Patent
National Cheng Kung University | Date: 2016-02-29

A photonic microwave generation apparatus and a method thereof are disclosed. A comb-like optical signal generation module of the photonic microwave generation apparatus generates a comb-like optical signal. The comb-like optical signal is injected into a photonic microwave generation module of the photonic microwave generation apparatus, wherein the photonic microwave generation module includes a microwave generation laser. An optical power and a carrier frequency of the comb-like optical signal are adjusted so as to place the microwave generation laser in period-one nonlinear dynamics, and, at the same time, to phase-lock an oscillation sideband of the period-one nonlinear dynamics by one harmonic of the comb-like optical signal. Under such operation, the microwave generation laser emits an output optical signal that carries a microwave signal of a narrow linewidth and a stable frequency, which can be retrieved from the output optical signal by using a photodetector.


Patent
National Cheng Kung University | Date: 2016-08-19

An electrolyte for a dye-sensitized solar cell is disclosed. The electrolyte includes a solvent being one selected from a group consisting of gamma-butyrolactone (gBL), propylene carbonate (PC) and 3-methoxypropionitrile (MPN), and a polymer mixed with the solvent to form an electrolyte solution, wherein when the solvent is one of gBL and PC, the polymer is one selected from a group consisting of polyacrylonitrile (PAN), polyvinyl acetate (PVA), poly(acrylonitrile-co-vinyl acetate) (PAN-VA) and a combination thereof; and when the solvent is MPN, the polymer includes one of a mixture of poly(ethylene oxide (PEO) and polyvinylidene fluoride (PVDF), and a mixture of PEO and polymethylmethacrylate (PMMA).


Patent
National Cheng Kung University | Date: 2017-02-28

A stability analyzing apparatus is in cooperation with a DC power system having a bus terminal connected to at least a load, and comprises a perturbation signal generating module, a signal processing module and a determining module. The perturbation signal generating module generates a perturbation signal injected into the bus terminal to obtain a transfer function of the bus terminal impedance. The signal processing module is electrically connected to the perturbation signal generating module and calculates the slope of the transfer function of the bus terminal impedance to obtain a transfer function of the bus terminal impedance slope. The determining module is electrically connected to the signal processing module and determines the stability tendency of the DC power system according to the transfer function of the bus terminal impedance slope. A stability analyzing method is also disclosed.


Patent
National Cheng Kung University | Date: 2016-07-11

The present invention relates to an immunostimulatory nanocomplex. The immunostimulatory nanocomplex comprises polyglutamic acid (PGA), a first positively charged substance, a second positively charged substance and a dengue viral protein for holding the dengue viral protein inside. The immunostimulatory nanocomplex is characterized by having a nonuniformally and positively charge distribution along a radial direction thereof. The nonuniformally and positively charge distribution comprises a first electrically charged portion having substantially electrical neutrality, a second electrically charged portion surrounding the first electrically charged portion, and a third electrically charged portion surrounding the second electrically charged portion. The third electrically charged portion has a third volume charge density more than a second volume charge density of the second electrically charged portion, thereby enhancing CD8(+) T-cell response and higher antibody titer after administrating an organism with the immunostimulatory nanocomplex.


A low power consumption sigma-delta modulator architecture capable of dynamic detection of output signal strength to change dynamic range, a method for implementing low power consumption circuit thereof, and a method for automatically correcting and extending dynamic range of the sigma-delta modulator are provided. An automatic correction unit is utilized to detect system output signal strength of the sigma-delta modulator, compare system input signal specifications to come out multiple sets of dynamic range curves, and thereby extract an appropriate combination of system order and feed-forward coefficients so as to extend the system dynamic range. The circuit architecture of the automatic correction unit is in a digital circuit form, including a digital signal processor, a counter and register array, a comparator, a digital coefficient controller, a feed-forward gain control unit and a system order control unit.

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