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Zhao X.-G.,National Biological Protection Engineering Center | Xu X.-X.,National Biological Protection Engineering Center | Fu N.,National Biological Protection Engineering Center | Liu Z.-G.,National Biological Protection Engineering Center | And 2 more authors.
Applied Mechanics and Materials | Year: 2014

Mobile operating room plays a very important role in treating patients in natural disasters such as earthquake and tsunami. However, development of surgical technology in the 21st century provides the opportunity for constructing a mobile operating room, which is also increasingly dependent on demonstrating safety, efficacy and cost effectiveness. Success in planning an efficiently mobile hybrid operating room many factors must be considered including pace limited, workflow, protocols, equipment and ergonomics. This paper will present several considerations of setting up a mobile hybrid operating room. © (2014) Trans Tech Publications, Switzerland.


Qiao L.,National Biological Protection Engineering Center | Du Y.,National Biological Protection Engineering Center | Chen F.,National Biological Protection Engineering Center | Wu J.,National Biological Protection Engineering Center | Wu T.,National Biological Protection Engineering Center
Journal of Vibroengineering | Year: 2016

To solve the defects of low degradation efficiency and high cross-contamination risk in the conventional ultrasonic processor, a non-contact ultrasonic degradation system was developed. Through finite-element modal analysis, the natural frequencies of the first ten modes of the diaphragm with dome-shaped structure were found to have a ladder-like distribution, which provides a possibility to utilize the synchronous resonance of multiple modes. The effects of curvature radius, thickness and preload force on the synchronous resonance of multiple modes are studied using the control variate method, and then the structural parameters and the preload force are optimized. Based on these results, the diaphragm was manufactured, the experimental platform of the non-contact ultrasonic degradation was established, and its degradation efficiency was evaluated. The experimental results proved that the non-contact ultrasonic degradation system was able to effectively degrade Bacillus atrophaeus. © JVE INTERNATIONAL LTD.


Li Y.-J.,Tianjin University | Li Y.-J.,National Biological Protection Engineering Center | Zhu N.,Tianjin University | Jia H.-Q.,National Biological Protection Engineering Center | And 3 more authors.
Journal of Zhejiang University: Science B | Year: 2012

Objective: Chlorine dioxide (CD) gas has been used as a fumigant in the disinfection of biosafety laboratories. In this study, some experiments were conducted to assess the inactivation of spores inoculated on six materials [stainless steel (SS), painted steel (PS), polyvinyl chlorid (PVC), polyurethane (PU), glass (GS), and cotton cloth (CC)] by CD gas. The main aims of the study were to determine the sporicidal efficacy of CD gas and the effect of prehumidification before decontamination on sporicidal efficacy. Methods: Material coupons (1.2 cm diameter of SS, PS, and PU; 1.0 cm×1.0 cm for PVC, GS, and CC) were contaminated with 10 μl of Bacillus subtilis var. niger (ATCC 9372) spore suspension in mixed organic burden and then dried in a biosafety cabinet for 12 h. The spores were recovered by soaking the coupons in 5 ml of extraction liquid for 1 h and then vortexing the liquid for 1 min. Results: The log reductions in spore numbers on inoculated test materials exposed to CD gas [0.080% (volume ratio, v/v) for 3 h] were in the range of from 1.80 to 6.64. Statistically significant differences were found in decontamination efficacies on test material coupons of SS, PS, PU, and CC between with and without a 1-h prehumidification treatment. With the extraction method, there were no statistically significant differences in the recovery ratios between the porous and non-porous materials. Conclusions: The results reported from this study could provide information for developing decontamination technology based on CD gas for targeting surface microbial contamination.


Zhao X.-G.,National Biological Protection Engineering Center | Xu X.-X.,National Biological Protection Engineering Center | Fu N.,National Biological Protection Engineering Center | Zhang W.-C.,National Biological Protection Engineering Center | And 3 more authors.
Applied Mechanics and Materials | Year: 2013

To cope with biochemical terrorism attack and public health emergency, it is urgently necessary to develop a kind of renewable toxic gas filtering apparatus in order to solve problems of regular replacement and short protective time of existing toxic gas filtering apparatus. Based on the analysis of the deficiency of existing toxic gas filtering apparatus, a kind of renewable toxic gas filtering apparatus was developed using the technology of variable pressure. The contaminated air could be purified by renewable toxic gas filtering apparatus finally provide pure air for persons in the vessel compartment. Renewable toxic gas filtering apparatus can satisfy the NBC protective of civil building. © (2013)Trans Tech Publications,Switzerland.


Qiao L.,National Biological Protection Engineering Center | Du Y.,National Biological Protection Engineering Center | Chen F.,National Biological Protection Engineering Center | Cheng Z.,National Biological Protection Engineering Center | And 4 more authors.
Applied Mechanics and Materials | Year: 2013

An ultrasonication system for cells disruption is developed to extract nucleic acid from cells. The structure and operating principle of the ultrasonication system are explained, after which the key problems are stated. Based on finite element modal analysis, the top-ten natural frequencies of the round-shaped vibrating diaphragm are found having a character of stepped distribution, which can be divided into three grades. To optimize the vibration performance of vibrating diaphragm, simulation based on ANSYS is performed, the results of which show that medium grade frequency decreases with the increase of diameter while increases linearly with the increase of thickness. © (2013) Trans Tech Publications, Switzerland.

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