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Buenos Aires, Argentina

Santini-Araujo E.,Laboratory of Orthopaedic Pathology | Olvi L.G.,Laboratory of Orthopaedic Pathology | Muscolo D.L.,Italian Hospital | Velan O.,Italian Hospital | And 2 more authors.
Acta Cytologica

Objective: Percutaneous needle biopsy is an effective and safe technique for obtaining diagnostic material from bone lesions. Study Design: We describe the technical details of fine needle aspiration and core needle biopsy performed in our laboratory of orthopedic pathology. Results: With these procedures, we obtained accurate diagnosis in 83% of 7,375 cases, sent by different orthopedic centers in our country, over a period of 21 years (1986-2007). Conclusion: We describe the percutaneous needle procedure (fine needle aspiration, core needle biopsy), the handling of the materials in detail, the different cytological techniques, as well as the advantages of the procedures and how to avoid its disadvantages. We believe that accurate diagnosis with bone needle biopsy mainly depends on the training of the surgical cytologist and the pathologist, who must integrate all the knowledge on the clinical data, image diagnosis, histological procedures and the experience in the histopathological interpretation of bone lesions. © 2010 S. Karger AG, Basel. Source

Olmedo D.G.,University of Buenos Aires | Paparella M.L.,University of Buenos Aires | Brandizzi D.,National Atomic Energy Commission | Cabrini R.L.,University of Buenos Aires
International Journal of Oral and Maxillofacial Surgery

The aim of this study was to report 2 novel clinical cases of reactive lesions of the peri-implant mucosa associated with titanium dental implants where metal-like particles were observed histologically. In both cases, the lesions were diagnosed as epulis, based on clinical evidence. Extirpation biopsies were carried out. Case 1 was diagnosed as pyogenic granuloma and case 2 as peripheral giant cell granuloma. The presence of metal-like particles in the tissues suggests that the etiology of the lesions might be related to the corrosion process of the metal structure. This is the first case of pyogenic granuloma to be reported in association with dental implants. All clinical cases of soft tissue lesions associated with implants should be reported to contribute to the understanding of the etiology and pathogeny of these lesions. © 2009 International Association of Oral and Maxillofacial Surgeons. Source

Braslavsky S.E.,Max Planck Institute for Chemistry | Braun A.M.,Karlsruhe Institute of Technology | Cassano A.E.,National University of Santa | Emeline A.V.,Saint Petersburg State University | And 4 more authors.
Pure and Applied Chemistry

This glossary of terms covers phenomena considered under the very wide terms photocatalysis and radiation catalysis. A clear distinction is made between phenomena related to either photochemistry and photocatalysis or radiation chemistry and radiation catalysis. The term "radiation" is used here as embracing electromagnetic radiation of all wavelengths, but in general excluding fast-moving particles. Consistent definitions are given of terms in the areas mentioned above, as well as definitions of the most important parameters used for the quantitative description of the phenomena. Terms related to the up-scaling of photocatalytic processes for industrial applications have been included. This Glossary should be used together with the Glossary of terms used in photochemistry, 3rd edition, IUPAC Recommendations 2006: (doi:10.1351/pac200779030293) as well as with the IUPAC Compendium of Chemical Terminology, 2nd ed. (the "Gold Book" 2006-; doi:10.1351/goldbook), because many terms used in photocatalysis are defined in these documents. © 2011 IUPAC. Source

Pirchio R.,National Atomic Energy Commission | Sanchez H.,National Atomic Energy Commission | Domazet W.,Sanatorium Dr Julio Mendez
Radiation Measurements

During interventional radiology (IR) and cardiology (IC) procedures, medical staff can receive high doses to their eye lenses. The Retrospective Evaluation of Lens Injuries and Dose study organized in Argentina in 2010 found incipient opacity in 50% of IC physicians and 41% of IC technicians/nurses. These results, added to the recommendations of the International Commission on Radiological Protection, which lowered their former occupational equivalent dose limit for the lens, led us to assess the eye lens dose, Hp(3), during interventional procedures. To this end, a new dosemeter was designed and calibrated at the National Atomic Energy Commission of Argentina to evaluate Hp(3). Personal dose equivalent (Hp(10)), and Hp(3) were assessed for 3 months in two IC and IR departments. An Alderson phantom was used to simulate monthly exposures of five occupational staff members. Hp(3) and Hp(10) were obtained monthly for 14 occupational staff members exposed to 121 IR and IC procedures. We concluded that the annual effective dose and Hp(3) were lower than 0.3 and 10 mSv, respectively and the average cumulative Hp(3) for working life was lower than 400 and 200 mSv for physicians and technicians/scrub nurse, respectively. An occupational annual dose constraint of 0.3 mSv was calculated. © 2014 Elsevier Ltd. All rights reserved. Source

Thomasz L.,National Atomic Energy Commission | Coulonval K.,Free University of Colombia | Salvarredi L.,National Atomic Energy Commission | Oglio R.,National Atomic Energy Commission | And 6 more authors.
Molecular and Cellular Endocrinology

Although thyroid gland function is mainly under the control of pituitary TSH, other factors, such as iodine, play a role in this process. The thyroid is capable of producing different iodolipids such as 6-iodo-deltalactone and 2-iodohexadecanal (2-IHDA). It was shown that these iodolipids mimic some of the inhibitory effects of excess iodide on several thyroid parameters. Objectives: To study the effect of 2-IHDA on cell proliferation and apoptosis in FRTL-5 cells. Results: FRTL-5 cells were grown in the presence of TSH and treated with increasing concentrations of KI and 2-IHDA (0.5, 5, 10 and 33 μM) for 24, 48 and 72 h. Whereas KI inhibited cell proliferation only at 33 μM after 72 h of treatment, 2-IHDA inhibited in a time and concentration dependent manner. Analysis of cell cycle by flow cytometric DNA analysis revealed an accumulation of cells in G1 phase induced by 2-IHDA. The expression of cyclin A, cyclin D1 and cyclin D3 were reduced after treatment with 2-IHDA whereas CDK4 and CDK6 proteins were not modified. 2-IHDA induced a dynamic change in cytoplasmic to nuclear accumulation of p21 and p27 causing these proteins to be accumulated mostly in the nucleus. We also observed evidence of a pro-apoptotic effect of 2-IHDA at highest concentrations. No significant effect of KI was observed. Conclusion: These results suggest that the inhibitory effects of 2-IHDA on FRTL-5 thyroid cell proliferation are mediated by cell cycle arrest in G1/S phase and cell death by apoptosis. © 2015 Elsevier Ireland Ltd. Source

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