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Kustareva L.A.,National Academy of science of Kyrgyz Republic | Naseka A.M.,Saint Petersburg State University
Aquatic Ecosystem Health and Management | Year: 2015

The territory of Kyrgyz Republic (or Kyrgyzstan) is interesting from a zoogeographical point of view, as it straddles several major ecoregions: Balkhash Lake basin, Chu River drainage, Lake Issyk-Kul basin, Talas-Ters drainage, Upper Syr Darya system, Upper Amu Darya system and Tarim basin. Species composition of fish faunas of all ecoregions are discussed and endemic species and subspecies listed. The degree of endemism is notable, reaching 55 and 70% in the Talas River and Issyk-Kul Lake ecoregions, respectively. Some aspects of human impact on native fish populations are analysed, including the introduction and establishment of exotic species that dominate some lakes and reservoirs, fisheries and aquaculture. A review of fishery resources management underlines the need to formulate a compromise strategy for the conservation of unique native fish communities, and the development and management of capture fisheries, based on both native and exotic species, and aquaculture in Kyrgyzstan. © 2015 AEHMS. Source


Korjenkov A.M.,National Academy of science of Kyrgyz Republic | Korjenkov A.M.,Russian Academy of Sciences | Kol'chenko V.A.,National Academy of science of Kyrgyz Republic | Rott P.G.,University of Bonn | Abdieva S.V.,National Academy of science of Kyrgyz Republic
Geotectonics | Year: 2012

The data presented in this paper show that in historical time the Chuy Basin in Kyrgyzstan was repeatedly subjected to strong earthquakes, which affected the inhabitants and the economic and political situation at that time. The deformed buildings in the Novopokrovka site of ancient settlements situated in the central part of the basin unequivocally indicate seismic damage and subsequent abandonment of the settlement. The earthquake happened at the end of the Karakhanid epoch (the end of the 12th century A. D.). The intensity of seismic oscillations (I = VIII-IX) at the site was reinforced by unfavorable engineering geology conditions. The source of the earthquake was probably related to displacements along the piedmont Ysyk-Ata Fault located to the south of the site. © 2012 Pleiades Publishing, Ltd. Source


Korzhenkov A.M.,Russian Academy of Sciences | Kol'chenko V.A.,Kyrgyz Russian Slavic University | Luzhanskii D.V.,National Academy of science of Kyrgyz Republic | Abdieva S.V.,National Academy of science of Kyrgyz Republic | And 8 more authors.
Izvestiya, Physics of the Solid Earth | Year: 2016

We carried out archaeoseismological studies in the Southern Issyk-Kul region (Kyrgyz Tien Shan) and obtained radiocarbon datings of the collected samples. These data suggest that the sources of strong earthquakes have occurred in this territory in the 11th and (probably) 16th centuries. These earthquakes had magnitude M ≥ 7 and seismic intensity of at least I ≥ 9. The sources of these earthquakes were associated with the local adyr (piedmont) faults—components of the Pre-Terskei border fault. Our results demonstrate considerable underestimation of the seismic hazard for the South Issyk-Kul region in the latest Seismic Zoning Map of Kyrgyz Republic (2012), which should be taken into account in the construction of the new seismic zoning map for Kyrgyzstan. © 2016, Pleiades Publishing, Ltd. Source


Korzhenkov A.M.,Russian Academy of Sciences | Abdieva S.V.,Kyrgyz Russian Slavic University | Fortuna A.B.,National Academy of science of Kyrgyz Republic | Charimov T.A.,National Academy of science of Kyrgyz Republic | Yudakhin A.S.,Russian Academy of Sciences
Russian Geology and Geophysics | Year: 2015

Moraines studied in the Chon-Kyzylsuu River valley (southeastern Lake Issyk-Kul region, Tien Shan) were mobilized during historic and prehistoric large earthquakes. Seismic triggers of moraine mobilization included the M > 8 Kebin earthquake of 1911 and prehistoric events that produced rockslides, landslides, and multiple fault scarps. Rockslides in the Chon-Kyzylsuu basin are located in the hanging wall of the Terskey border thrust fault. The observed deformation results from at least four prehistoric earthquakes in the second half of the Holocene (early 20th century BC, early 11th century BC, middle 8th century BC, and early 2nd century BC), with local shaking intensity I > 7. © 2015 V.S. Sobolev IGM, Siberian Branch of the RAS. Published by Elsevier B.V. Source


Wilkins M.R.,Imperial College London | Aldashev A.A.,National Academy of science of Kyrgyz Republic | Wharton J.,Imperial College London | Rhodes C.J.,Imperial College London | And 15 more authors.
Circulation: Cardiovascular Genetics | Year: 2014

Background-Human variation in susceptibility to hypoxia-induced pulmonary hypertension is well recognized. Highaltitude residents who do not develop pulmonary hypertension may host protective gene mutations. Methods and Results-Exome sequencing was conducted on 24 unrelated Kyrgyz highlanders living 2400 to 3800 m above sea level, 12 (10 men; mean age, 54 years) with an elevated mean pulmonary artery pressure (mean±SD, 38.7±2.7 mm Hg) and 12 (11 men; mean age, 52 years) with a normal mean pulmonary artery pressure (19.2±0.6 mm Hg) to identify candidate genes that may influence the pulmonary vascular response to hypoxia. A total of 140 789 exomic variants were identified and 26 116 (18.5%) were classified as novel or rare. Thirty-three novel or rare potential pathogenic variants (frameshift, essential splice-site, and nonsynonymous) were found exclusively in either ≥3 subjects with high-altitude pulmonary hypertension or ≥3 highlanders with a normal mean pulmonary artery pressure. A novel missense mutation in GUCY1A3 in 3 subjects with a normal mean pulmonary artery pressure encodes an α1-A680T soluble guanylate cyclase (sGC) variant. Expression of the α1-A680T sGC variant in reporter cells resulted in higher cyclic guanosine monophosphate production compared with the wild-type enzyme and the purified α1-A680T sGC exhibited enhanced sensitivity to nitric oxide in vitro. Conclusions-The α1-A680T sGC variant may contribute to protection against high-altitude pulmonary hypertension and supports sGC as a pharmacological target for reducing pulmonary artery pressure in humans at altitude. © 2014 American Heart Association, Inc. Source

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