Nanyang Technological University is a young, research-intensive university in Singapore. It is one of the largest public universities in Singapore.NTU was inaugurated in 1991, originally as an English-medium technical and teaching college occupying the grounds of the former Nanyang University, a Chinese-medium university which had been consolidated into the National University of Singapore in 1980. Over the years, NTU has grown to become a full-fledged research university, and currently provides a high-quality global education to close to 33,000 undergraduate and postgraduate students. The student body includes top scholars and international olympiad medallists from the region and beyond. Hailing from more than 70 countries, the university's 4000-strong teaching and research staff also bring dynamic international perspectives and years of solid industry experience.In recent years, various college and university rankings have placed NTU amongst the top universities in Asia and beyond. In the 2014 QS World University Rankings, NTU is ranked 39th globally , and is placed 1st in the world among young universities according to the 2014 QS Top 50 Under 50. NTU's College of Engineering is also ranked 9th in the world according to the latest 2014 QS World University Rankings by Faculty. In the 2014 Times Higher Education World University Rankings, NTU is ranked at 61st globally . NTU's business school, Nanyang Business School, was rated 64th in the world by the Economist Intelligence Unit in 2013. Wikipedia.
Nanyang Technological University | Date: 2017-01-06
An analog-to-digital converter (ADC) is provided, having two comparators, two digital-to-analog converters (DACs), and an adder circuit. The ADC receives an input value and, over a plurality of conversion cycles of the ADC, generates an output value representative of the input value. Each respective DAC generates a plurality of threshold levels, which are defined, at least in part, by predetermined redundancy levels that are binary-scaled. The comparator arrangement provides an output code in a respective conversion cycle and, for at least two adjacent conversion cycles, the two comparators collectively provide 2-bit output codes. The adder circuit provides a plurality of output bits of the output value, and is capable of overlapping and adding a first significant bit of the 2-bit output code provided for a predetermined conversion cycle with a second significant bit of the 2-bit output code provided for a previous conversion cycle to generate one output bit.
Nanyang Technological University and National University of Singapore | Date: 2017-06-28
The present invention provides a method for determining the presence of a microorganism in a sample using an electrochemically active reporter, wherein the method comprises (a) contacting the sample with an electrochemically active reporter, wherein the electrochemically active reporter is a conjugate comprising a sugar moiety and a redox active reporter moiety that are covalently linked such that the covalent bond can be enzymatically cleaved in the presence of the microorganism by an enzyme expressed by the microorganism, wherein the redox active reporter moiety is selected from the group consisting of resorufin and compounds of formula (I) as defined herein, under conditions that allow enzymatic cleavage of the covalent bond between the sugar moiety and the redox active reporter moiety and reduction of the redox active report moiety in the presence of the microorganism; (b) electrochemically determining the released redox active reporter moiety; and (c) determining the presence of the microorganism and, optionally, number of the microorganisms in the sample based on the determined released redox active reporter moiety. Also encompassed are the electrochemically active reporters used in the described methods and their use for determination of the presence of microorganisms in a sample.
Nanyang Technological University | Date: 2017-02-22
There is provided a compound of formula I, having the structure: wherein R1 to R5 have the meanings given in the description.
Nanyang Technological University | Date: 2017-05-03
Systems and methods are proposed for synthetic biology design and host cell simulation. In one form, a synthetic biology design system is proposed, comprising a model conversion component configured to: receive genetic circuit data indicative of a user-specified genetic circuit design; identify, from the genetic circuit data, constituent parts of the genetic circuit design, and the connections between the constituent parts; obtain mathematical models corresponding to the constituent parts; and combine the obtained mathematical models into a composite model configured to generate genetic circuit output data based on input data indicative of one or more of: free RNA polymerase concentration, free ribosome concentration and rRNA concentration. The system further comprises a host cell simulation component configured to receive, as input, the genetic circuit output data from the composite model, and based on the genetic circuit output data, generate host cell output data representing a physiological state of the host.
Nanyang Technological University | Date: 2017-05-24
A biological tissue adhesive composition is provided. The biological tissue adhesive composition comprises one or more macromolecules grafted with at least one catechol moiety and comprising at least one cross-linkable functional group, a first cross-linker for cross- linking the at least one catechol moiety, wherein the first cross-linker comprises or consists or 10 a multivalent metal ion, and a second cross-linker for covalently cross-linking the at least one cross-linkable functional group, wherein the one or more macromolecules are cross-linked by (a) complex formation between the at least one catechol moiety and the multivalent metal ion, and (b) covalent bonding of the at least one cross-linkable functional group with the second cross-linker. Fabrication method and working principle of a biological tissue adhesive 15 composition are also provided. FIG. 1 (figure for publication with abstract)
Hebrew University of Jerusalem and Nanyang Technological University | Date: 2017-01-18
The invention provides a spectrally selective solar thermal coating, formed as a continuous uniform layer, combining a light-absorbing coating and an infrared (IR) reflecting layer positioned on top of the absorber coating. The coating of the invention is adapted for use in a plurality of applications, including amongst many control of stray light and absorptivity in thermosolar devices.
Nanyang Technological University | Date: 2017-02-03
A polyimide-carbon nanotube composite film is provided. The composite film includes a carbon nanotube, and a polyimide obtainable by imidizing a poly(amic acid).
Nanyang Technological University | Date: 2017-03-22
Various embodiments provide a method of forming a light-emitting device. The method may include providing a multi-layer structure, wherein the multi-layer structure includes a substrate, a first semiconductor layer of a first conductivity type, an active layer and a second semiconductor layer of a second conductivity type in sequence, and includes at least one metal contact formed on at least one of the first semiconductor layer and the second semiconductor layer. The method further includes forming at least one trench over the at least one metal contact, and forming at least one metal support in the at least one trenches.
Nanyang Technological University | Date: 2017-03-01
The present invention is directed to enzymes having Asx-specific ligase and cyclase activity and to nucleic acids encoding those as well as methods of the manufacture of said enzymes. Further encompassed are methods and uses of these enzymes.
Nanyang Technological University | Date: 2017-02-08
In various embodiments, a method of recycling a carrier substrate is provided. The method comprises: providing said carrier substrate; forming a buffer layer by depositing a suitable material on the carrier substrate, forming one or more component layers over the buffer layer; separation of the one or more component layers from the carrier substrate so that at least a portion of the buffer layer remains on the carrier substrate after separation; and forming a further buffer layer from the portion of the buffer layer after the separation by depositing the suitable material to recycle the carrier substrate. Also a method of recycling a substrate is provided that comprises: forming an insulating layer on a substrate; removing a first portion of the insulating layer to expose a first portion of the substrate; forming one or more component layers over the first portion of the substrate; and separating the one or more component layers from the substrate for recycling the substrate.