Geumcheon gu, South Korea
Geumcheon gu, South Korea

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The present invention relates to a PCR heating block having heaters repeatedly arranged thereon is capable of preventing the radial thermal distribution generated from the individual heaters and the non-uniform heat superposition between the adjacent heaters to improve the PCR yield and further capable of requiring no separate temperature controlling means to achieve the miniaturization and integration of a device. According to the present invention, furthermore, a PCR device is capable of amplifying a plurality of nucleic acid samples at the same time and rapidly by using a PCR heating block on which heater units are repeatedly arranged and a plate-shaped PCR reaction unit and also capable of measuring successively generated optical signals or electrochemical signals to in real time check the nucleic acid amplification.


Patent
Nanobiosys Inc. | Date: 2016-12-21

The present invention relates to a microfluidic chip and a real-time analysis device using same, and more specifically, to a microfluidic chip and a real-time analysis device using same capable of securing reliability of measurement results by appropriately preventing reduction of optical signal sensitivity due to bubbles included in a fluid. According to one embodiment of the present invention, the microfluidic chip is provided. The microfluidic chip comprises: at least one reaction chamber which comprises at least one optical measuring area, and in which a random reaction of a fluid received therein takes place; and a bubble-eliminating portion comprising a light transmitting material which protrudes from an the inner surface of an upper part of the microfluidic chip toward the inside of the reaction chamber, to prevent bubbles included in the fluid from being included in the optical measuring area.


One embodiment of the present invention relates to a nucleic acid extraction device, which can realize automation, ultra-miniaturization and super-high speed in the nucleic acid extraction reaction, have no limitation to the biological specimens, such as sputum, blood, cells, urine, saliva, tissues, etc., minimize the used amount of the sample solution, and also maintain and/or improve the nucleic acid extraction efficiency with reliability.


A nucleic acid extraction device, which can realize automation, ultra-miniaturization and super-high speed in the nucleic acid extraction reaction, has no limitation to the type of biological specimens that can be used, such as sputum, blood, cells, urine, saliva, tissues, etc., minimize the used amount of the sample solution, and also maintain and/or improve the nucleic acid extraction efficiency with reliability.


Patent
Nanobiosys Inc. | Date: 2013-02-27

According to the present invention, a PCR device including two heating blocks which is used for nucleic acid amplification reactions is disclosed. Using the PCR device of the present invention, nucleic acid amplification reactions can be efficiently performed.


Patent
Nanobiosys Inc. | Date: 2015-02-09

The present invention relates to a microfluidic chip and a real-time analysis device using same, and more specifically, to a microfluidic chip and a real-time analysis device using same capable of securing reliability of measurement results by appropriately preventing reduction of optical signal sensitivity due to bubbles included in a fluid. According to one embodiment of the present invention, the microfluidic chip is provided. The microfluidic chip comprises: at least one reaction chamber which comprises at least one optical measuring area, and in which a random reaction of a fluid received therein takes place; and a bubble eliminating portion comprising a light transmitting material which protrudes from an the inner surface of an upper part of the microfluidic chip toward the inside of the reaction chamber, to prevent bubbles included in the fluid from being included in the optical measuring area.


One embodiment of the present invention relates to a PCR device provided with a unidirectional sliding means and a method for PCR using same. According to the present invention, the amount of samples treated can be increased by simultaneously, rapidly, and accurately performing a PCR on a large number of samples through sequential thermal contact between a thermal block in which at least two heaters are repeatedly arranged and a PCR chip in which at least two reaction chambers are repeatedly arranged. Also, the present invention is capable of: significantly improving PCR yield by preventing radial heat distribution generated by each heater and consequent non-uniform thermal overlap between neighboring heaters; significantly contributing to size reduction and integration of the device by not requiring a separate temperature control means; simultaneously and rapidly amplifying multiple nucleic acid samples by using the thermal block in which heater units are repeatedly arranged and a plate-shaped PCR reacting portion; and confirming a nucleic acid amplifying step in real time by measuring continuous optical signals or electrochemical signals.


The present invention relates to a PCR heating block having heaters repeatedly arranged thereon is capable of preventing the radial thermal distribution generated from the individual heaters and the non-uniform heat superposition between the adjacent heaters to improve the PCR yield and further capable of requiring no separate temperature controlling means to achieve the miniaturization and integration of a device. According to the present invention, furthermore, a PCR device is capable of amplifying a plurality of nucleic acid samples at the same time and rapidly by using a PCR heating block on which heater units are repeatedly arranged and a plate-shaped PCR reaction unit and also capable of measuring successively generated optical signals or electrochemical signals to in real time check the nucleic acid amplification.


One embodiment of the present invention relates to a PCR device provided with a unidirectional sliding means and a method for PCR using same. According to the present invention, the amount of samples treated can be increased by simultaneously, rapidly, and accurately performing a PCR on a large number of samples through sequential thermal contact between a thermal block in which at least two heaters are repeatedly arranged and a PCR chip in which at least two reaction chambers are repeatedly arranged. Also, the present invention is capable of: significantly improving PCR yield by preventing radial heat distribution generated by each heater and consequent non-uniform thermal overlap between neighboring heaters; significantly contributing to size reduction and integration of the device by not requiring a separate temperature control means; simultaneously and rapidly amplifying multiple nucleic acid samples by using the thermal block in which heater units are repeatedly arranged and a plate-shaped PCR reacting portion; and confirming a nucleic acid amplifying step in real time by measuring continuous optical signals or electrochemical signals.


Patent
Nanobiosys Inc. | Date: 2015-05-18

According to the present invention, a PCR device including two heating blocks which is used for nucleic acid amplification reactions is disclosed. Using the PCR device of the present invention, nucleic acid amplification reactions can be efficiently performed.

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