Time filter

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A new compound [C19H19N3O3F2Cl·C4H3O4·H2O] (I), (7-((7S)-7-aminospiro[2.4]heptan- 5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid fumaric acid monohydrate), was synthesized and structurally characterized by single-crystal X-ray diffraction, 1H NMR, 14C spectra and mass spectra. I crystallizes in monoclinic, space group P21/c with a = 8.495(2), b = 12.545(3), c = 11.832(3) Å, β = 103.37(1)°, V = 1226.8(5) Å3, Z = 2, Mr = 543.90, Dc = 1.472 g/cm3, F(000) = 564, μ = 0.225 mm-1, the final R = 0.0307 and wR = 0.0892 for 6886 observed reflections with I > 2σ(I). X-ray diffraction analysis reveals that the quinolinone ring is almost coplanar, and the pyrrole ring adopts an envelope form. Packing of crystal I is constructed and stabilized by the N-H⋯O, O-H⋯O and N-H⋯Cl hydrogen bonds together with C-H⋯π interations. © 2016, Fujian Institute of Research of the Structure of Matter. All rights reserved. Source

Li D.,Nanjing University of Technology | Li D.,NanJing Polytechnic Institute | Hu J.,Nanjing University of Technology | Low Z.-X.,University of Bath | And 2 more authors.
Industrial and Engineering Chemistry Research

Expanded polytetrafluoroethylene (ePTFE) is one of the most common membrane materials, but the intrinsic hydrophobic nature is a major reason for deteriorating performances in water purification. In this work, the influences of atomic layer deposition (ALD) seeding and subsequent ZnO nanorod (NR) growth on the surface morphologies and water permeability of ePTFE membranes was investigated. ZnO-ALD ePTFE membrane showed an order of magnitude increase in water permeation, owing to the substantial increase in surface hydrophilicity and surface area. The best-performing ZnO NRs membrane had a pure water flux (PWF) of 1764.3 L·m-2·h-1 (compared to 153.8 L·m-2·h-1 of the pristine ePTFE membrane). Suspension filtration experiments indicate that the ZnO NRs filter showed an increase of steady-state flux of more than 5 times and an increase of 29.7% in retention compared to that of the ePTFE membrane. Significantly, the novel ZnO NR filter exhibited good photocatalytic performance as demonstrated in the degradation of methyl orange (MO) solution. Therefore, the functionalized membrane can potentially overcome the inherent limitation in the trade-off effect and imply their superiority for controlling water quality. © 2016 American Chemical Society. Source

Yin J.,Nanjing University | Yin J.,NanJing Polytechnic Institute | Tao C.,Nanjing University | Cai P.,Nanjing University | Liu X.,Nanjing University
Applied Physics Letters

Acoustically inhomogeneous mediums with multiple scattering are often the nightmare of photoacoustic tomography. In order to break this limitation, a photoacoustic tomography scheme combining ultrasound interferometry and time reversal is proposed to achieve images in acoustically scattering medium. An ultrasound interferometry is developed to determine the unknown Green's function of strong scattering tissue. Using the determined Greens' function, a time-reversal process is carried out to restore images behind an acoustically inhomogeneous layer from the scattering photoacoustic signals. This method effectively decreases the false contrast, noise, and position deviation of images induced by the multiple scattering. Phantom experiment is carried out to validate the method. Therefore, the proposed method could have potential value in extending the biomedical applications of photoacoustic tomography in acoustically inhomogeneous tissue. © 2015 AIP Publishing LLC. Source

Zhu L.,Nanjing University of Science and Technology | Zhu L.,NanJing Polytechnic Institute | Ma Y.,Nanjing University of Science and Technology | Wu F.,Nanjing University of Science and Technology | And 2 more authors.
Jisuanji Jicheng Zhizao Xitong/Computer Integrated Manufacturing Systems, CIMS

Aiming at the risk-averse stochastic simulation optimization problems with multiple responses, by combining robust design approach with conditional value at risk criterion, an optimal strategy of mean-conditional value at risk was proposed based on Kriging model was proposed. Kriging models for mean response and conditional value at risk response were constructed respectively with meta modeling technology, and the decision model of mean-conditional value at risk with risk parameter description was built on this basis. The influence of environment variable's uncertainty on Pareto frontier of multiple responses was measured by bootstrap method, and the influence of different risk parameters on Pareto frontier was also given. The simulation experiment results showed that the proposed approach could dispose the risk-averse stochastic simulation optimization problems with multiple responses effectively. © 2016, Editorial Department of CIMS. All right reserved. Source

Wang Z.,Changchun University of Technology | Wang Z.,Jilin University | Hu J.,Changchun University of Technology | Du H.,NanJing Polytechnic Institute | And 3 more authors.
Journal of Pharmaceutical and Biomedical Analysis

The microwave-assisted ionic liquid homogeneous liquid-liquid microextraction (MA-IL-HLLME) coupled with high performance liquid chromatography with diode array detection (HPLC-DAD) was developed for the determination of anthraquinones, including aloe-emodin, emodin, chrysophanol and physcion in root of Rheum palmatum L. Several experimental parameters influencing the extraction efficiency, including amount of sample, type and volume of ionic liquid, volume and pH value of extraction medium, microwave power and extraction time, concentration of NH4PF6 as well as centrifugal condition were optimized. When 140 μL of ionic liquid ([C8MIM][BF4]) was used as an extraction solvent, target analytes can be extracted from sample matrix in one minute with the help of microwave irradiation. The MA-IL-HLLME is simple and quick. The calibration curves exhibited good linear relationship (r > 0.9984). The limits of detection and quantification were in the range of 0.015-0.026 and 0.051-0.088 μg mL-1, respectively. The spiked recovery for each analyte was in the range of 81.13-93.07% with relative standard deviations lower than 6.89%. The present method is free of volatile organic solvents, and represents lower expenditures of sample, extraction time and solvent, compared with ultrasonic and heat reflux extraction. The results indicated that the present method can be successfully applied to the determination of anthraquinones in medicinal plant. © 2016. Source

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