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Nanjing, China

Wang J.,Third Security | Wang J.,Shanghai JiaoTong University | Yao Z.-Q.,Shanghai JiaoTong University | Mei L.,Third Security | And 3 more authors.
Advances in Intelligent Systems and Computing | Year: 2013

A novel rapid impulsive noise denoising method for range image is presented. In a 2D scan line acquired by a laser range finder, distribution features of impulsive noises (INs) are analyzed, and then a mathematical representation of the features is provided by defining a few new coefficients. Subsequently, a rule-based distinguishing criterion is formulated to detect two types of INs: dropouts and invaders. The traditional mean filter is improved by an automotive non-IN neighbor searching procedure. A compositive algorithm with a very low computational complexity has been implemented as an embedded module in our self-developed software with copyright. An experiment on real range image is performed, and the results indicate that the proposed method can detect all the impulsive noises accurately and denoise them with a significant efficiency. It is proven that the method is suitable for practical applications on industrial or other fields. © 2013 Springer-Verlag.

Fan G.Q.,Nanjing Hospital of TCM
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2010

Literatures on acupuncture analgesia of the recent 30 years are analyzed through the target pain syndromes, points and tools selected for needling as well as the chosen direction, angle and depth of insertion. The relationship between effect of acupuncture analgesia and needling direction, angle as well as depth is initially optimized to enhance the analgesic effect. The result shows that the 3 factors are the key influences. However, studies on the above mentioned relation are still far from enough. Aiming at enhancing the effect of acupuncture analgesia and exploring the relative mechanism, it is held that multivariate analysis should be adopted to do systematic analysis on relationship between effect and mechanism of acupuncture analgesia and direction, angle and depth of the needle insertion.

Cao J.,Zhejiang University | Dun W.-L.,Nanjing Hospital of TCM
Talanta | Year: 2011

In this report, a novel means for the separation and sweeping of flavonoids (quercetin, rutin, calycosin, ononin and calycosin-7-O-β-D-glucoside) by microemulsion electrokinetic chromatography using mixed anionic and cationic surfactants as modified pseudostationary phase was presented. The optimized background electrolyte consisted of 0.5% (w/v) ethyl acetate, 2.0% (w/v) SDS, 9 mM DTAC, 4.0% (w/v) 1-butanol and 10 mM sodium borate or 25 mM phosphoric acid. We systematically investigated the separation and preconcentration conditions, including the concentrations of surfactant, types of sweeping, sample matrix, the effect of high salt or acetonitrile, and sample injection volume. It was found that the use of mixed surfactants significantly enhanced the separation efficiency through the change of the efficient electrophoretic mobility of analytes. Compared with normal sample injection, 185-508-fold sensitivity enhancement in terms of limit of detection was achieved through effective sweeping of large sample volume at 50 mbar pressure (up to 45% capillary length). At last, the proposed method was suitable for the determination of Radix Astragali sample. © 2011 Elsevier B.V. All rights reserved.

Yang X.,Nanjing Hospital of Integrated Chinese and Western Medicine | Wang Y.-Z.,Nanjing Hospital of Integrated Chinese and Western Medicine | Ye N.,Nanjing Hospital of Integrated Chinese and Western Medicine | Wang Y.,Nanjing Hospital of Integrated Chinese and Western Medicine | And 3 more authors.
World Chinese Journal of Digestology | Year: 2013

AIM: To observe the effect of treatment with Chinese medicine delivered by sonophoresis in patients with mild to moderate ulcerative colitis (UC), and to detect the changes in serum levels of cytokines. METHODS: This was a randomized controlled trial involving 67 patients with mild to moderate UC. These patients were randomly divided into either a treatment group (n = 33) or a control group (n = 34). All patients were given oral me-salazine enteric-coated tablets, 1.0 g, tid, while the treatment group was additionally given Chinese medicine (Shenlingbaizhu Powder) by sonophoresis, qd. The course of treatment was 3 months in both groups. Clinical symptoms were scored before treatment and 28, 56 and 84 d after treatment. Infammation degree was scored using the Baron's classification. Southerland disease active index (DAI) was calculated, and serum levels of interleukin-10 (IL-10) and IL-18 were measured before and after treatment. RESULTS: The total response rate was signif-cantly higher in the treatment group than in the control group (84.85% vs 70.59%, P < 0.05). The scores of abdominal pain, diarrhea and purulent stools were signifcantly decreased in both groups after treatment (all P < 0.05). The differences in Baron's scores and Southerland DAI before and after treatment were significant in both groups (both P < 0.05). Three months after treatment, the average serum level of IL-18 was signifcantly decreased and that of IL-10 was increased, which was more signifcant in the treatment group (P < 0.05). No adverse reaction was found in both groups. CONCLUSION: Chinese medicine delivered by sonophoresis shows an appreciated therapeutic effect in patients with mild to moderate UC, which may be related with the regulation of cy-tokine levels. © 2013 Baishideng Publishing Group Co., Limited. All rights reserved.

Chen J.,Nanjing Hospital of TCM | Qian J.,Nanjing Hospital of TCM | Fang M.,Nanjing Hospital of TCM | Yang X.,Nanjing Hospital of TCM | Huang X.,Nanjing Hospital of TCM
Journal of Leukemia and Lymphoma | Year: 2014

Objective To further elaborate the clinical characteristics, diagnosis, treatment and prognosis of primary cutaneous invasive epidermo-tropic CD8 positive cytotoxicity T-cell lymphoma. Methods The clinical characteristics, diagnosis and treatment of a patient with primary cutaneous invasive epidermo-tropic CD8 positive cytotoxicity T-cell lymphoma were summarized, and diagnosis and treatment of the disease from published literature were reviewed. Results After one year long, recurrence of exudative maculopapule on his body and limbs, a middle-aged male patient visited our hospital. Then, the patient was diagnosed as T2N0M0 I phase of primary cutaneous invasive epidermo-tropic CD8 positive cytotoxicity T-cell lymphoma based on results of skin biopsy, immunohistochemistry, T-cell gene rearrangement and PET-CT. Through integrative medicine treatment (combination of bruceolic oil emulsion and chemotherapy with GDP regimen), the patient achieved complete remission (CR). The treatment and follow-up continues till now and his condition was stable. Conclusions Clinical occurrence of primary cutaneous invasive epidermo-tropic CD8 positive cytotoxicity T-cell lymphoma is rare and early diagnosis is difficult. It could be diagnosed with histopathology combined with T-cell gene rearrangement. In order to avoid misdiagnosis, great caution should be taken during disease history inquiry and physical examination, should be early lesion for delayed healing of recurrent lesions, biopsy should be conducted as soon as possible and immunohistochemistry should be performed simultaneously, which will provide a good basis for further treatment. © 2014, Editorial Board of Journal of Leukemia and Lymphoma, All rights reserved.

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