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Chen Y.-Q.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Wang G.-M.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Zhang H.-M.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine
World Chinese Journal of Digestology | Year: 2013

Aim: To evaluate the value of endoscopic acetic acid-Lugol's iodine double staining in the diagnosis of early esophagus cancer. Methods: Patients with suspicious lesions first underwent Lugol's iodine staining, and the patients who showed no staining or poor staining were randomly divided into two groups: an acetic acid-Lugol's iodine double staining group (n = 30) and a Lugol's iodine staining group (n = 30). The double staining group underwent spraying with acetic acid first and then with Lugol's iodine solution. The mucosa was considered abnormal when mucosal discoloration or poor coloration developed after double staining, and biopsy of abnormal mucosa for histopathological examination was performed. Results: Eight (26.67%) patients of the double staining group were diagnosed with esophageal cancer by biopsy histopathological examination, containing 6 cases of esophageal squamous cell carcinoma and 2 cases of adenocarcinoma. Postoperative pathological diagnosis confirmed that all the 8 cases were early esophageal cancer. In the control group, 2 (6.67%) cases were found with esophageal squamous cell carcinoma by biopsy histopathological examination, and postoperative pathological diagnosis confirmed that both were early esophageal cancer. The detection rate of esophageal cancer in the double staining group was significantly higher than that in the Lugol' s iodine staining group (P < 0.05). The detection rate of esophageal squamous cell carcinoma showed no significant difference between the two groups (20.00% vs 6.67%, P > 0.05). Conclusion: Endoscopic acetic acid-Lugol' s iodine double staining can improve the detection rate of early esophageal cancer, especially adenocarcinoma. © 2013 Baishideng. All rights reserved. Source


Yang X.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Wang Y.-Z.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Ye N.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Wang Y.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine | Zhao J.,Nanjing Hospital of Integrated Traditional Chinese and Western Medicine
Chinese Journal of Tissue Engineering Research | Year: 2013

Background: Much clinical evidence have proved the effect of Hydrofiber™ dressing with silver in other wounds healing, but the reports on the effect of Hydrofiber™ dressing with silver in wounds healing after surgery for anal fistula are rare. Objective: To observe the therapeutic efficacy of Hydrofiber™ dressing with silver in wounds healing after surgery of anal fistula. Methods: Fifty-seven patients with anal fistula surgery were randomly divided into treatment group (n=29, Hydrofiber™ dressing with silver, once every 3 days) and the control group (n=28, Vaseline gauze, once per day). The level of wound pain during treatment, wound exudates situations, the frequency of dressing changes, the healing time and the cost of dressing changes were observed and compared. Results and Conclusion: The wound pain level during treatment, wound exudates situations, the healing time and the frequency of dressing changes in treatment group were all significantly less than those in the control group (P < 0.05), but the cost of dressing changes in the experimental group was significantly higher than that in the control group (P < 0.05). Hydrofiber™ dressing with silver for wounds healing after anal fistula surgery can obviously reduce the wound pain level during treatment, provide moist repair environment, accelerate wound healing, reduce the frequency of dressing changes and improve patient satisfaction. Source

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