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Yang Q.F.,Nanjing Foreign Language School | Wang L.N.,Nanjing University of Information Science and Technology
Applied Mechanics and Materials | Year: 2014

Fuzzy C-means clustering algorithm (FCM) is widely applied to the intrusion detection. To acquire a better division for intrusion data, a new method (DEFCM) presented in the paper which combines FCM and differential evolution algorithm (DE) is found application. As a start, several randomly initiated partitions are optimized by FCM, and then the result is provided to differential evolution algorithm. After that, the combined result is sent to FCM again to adjust the partition and obtain the final answer. The method can improve detection performance effectively. The KDDCUP1999 data set is used in the simulation experiment, and the result proves that the DEFCM algorithm has a comparatively high detection rate in intrusion detection. © (2014) Trans Tech Publications, Switzerland. Source

Yu G.X.,Nanjing Forestry University | Cao R.,Nanjing Foreign Language School | Luo M.,Nanjing Forestry University
Optik | Year: 2015

Based on classical EM field theory, the distributions of energy density and energy flow velocity in the 2-D cylinder cloak have been calculated. Due to the variable and special electromagnetic (EM) parameters, theoretical results indicate that the EM fields, EM energy density and EM energy flow are non-uniform in the cloak shell. The numerical simulations show that there is superluminal phenomena of the velocity of energy flow in the cloak shell, whether the EM field transmit along x-direction or along y-direction. © 2015 Elsevier GmbH. Source

Jiang T.-Y.,CAS Nanjing Institute of Soil Science | Jiang T.-Y.,Nanjing Agricultural University | Jiang T.-Y.,Wuhan Environmental Monitoring Center | Xu R.-K.,CAS Nanjing Institute of Soil Science | And 2 more authors.
Journal of Integrative Agriculture | Year: 2014

Two variable charge soils were incubated with biochars derived from straws of peanut, soybean, canola, and rice to investigate the effect of the biochars on their chemical properties and Pb(II) adsorption using batch experiments. The results showed soil cation exchange capacity (CEC) and pH significantly increased after 30 d of incubation with the biochars added. The incorporation of the biochars markedly increased the adsorption of Pb(II), and both the electrostatic and non-electrostatic adsorption mechanisms contributed to Pb(II) adsorption by the variable charge soils. Adsorption isotherms illustrated legume-straw derived biochars more greatly increased Pb(II) adsorption on soils through the non-electrostatic mechanism via the formation of surface complexes between Pb(II) and acid functional groups of the biochars than did non-legume straw biochars. The adsorption capacity of Pb(II) increased, while the desorption amount slightly decreased with the increasing suspension pH for the studied soils, especially in a high suspension pH, indicating that precipitation also plays an important role in immobilizing Pb(II) to the soils. © 2014 Chinese Academy of Agricultural Sciences. Source

Kai Y.,Nanjing University of Technology | Hu Y.,Nanjing University of Technology | Liu Y.,Nanjing University of Technology | Liang M.,Nanjing University of Technology | Xi Y.,Nanjing Foreign Language School
Fluid Phase Equilibria | Year: 2014

The solubilities of mercaptosuccinic acid in binary solvent mixtures consisting of water. +. methanol; water. +. ethanol; and water. +. acetone were determined by a dynamic method over the temperature from 278.15 to 333.15. K. The solubility data were correlated with the modified Apelblat equation and the semi-empirical Buchowski-Ksiazczak λh equation. The Buchowski-Ksiazczak λh equation can regress the solubility data much better than Apelblat equation. The calculated values are in good agreement with the experimental values. This study provides valuable data for the mercaptosuccinic acid purification by the preferential crystallization procedure. © 2013 Elsevier B.V. Source

Qiao C.,China Pharmaceutical University | Wei L.,China Pharmaceutical University | Dai Q.,China Pharmaceutical University | Zhou Y.,China Pharmaceutical University | And 5 more authors.
Journal of Cellular Physiology | Year: 2015

Oroxylin A is a flavonoid extracted from the root of Scutellaria baicalensis Georgi. Our previous research demonstrated that oroxylin A have various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion, and others. This paper explores the mechanism how oroxylin A induce apoptosis by regulating uncoupling protein 2 (UCP2) in human colon cancer cells. We found that the inhibition of UCP2 by UCP2 siRNA significantly increased the sensitivity of cells to drugs, reactive oxygen species (ROS) generation and the opening of mitochondrial permeability transition pore (MPTP) of CaCo-2 cells. We also found that UCP2 inhibition could lead to ROS-mediated MPTP activation. Furthermore, we demonstrated that oroxylin A triggered MPTP-dependent pro-apoptotic protein release from mitochondria to matrix and then induced apoptotic cascade by inhibiting UCP2. Intriguingly, the inhibition of UCP2 by oroxylin A was able to block Bcl-2 translocation to the mitochondria, keeping MPTP at open-state. In conclusion, we have demonstrated that UCP2 plays a key role in mitochondrial apoptotic pathway; UCP2s inhibition by oroxylin A triggers the MPTP opening, and promotes the apoptosis in CaCo-2 cells. J. Cell. Physiol. 230: 1054-1063, 2015. © 2014 Wiley Periodicals, Inc. Source

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