Dalin, Taiwan
Dalin, Taiwan

Nanhua University is a university located in Dalin Township, Chiayi County, Taiwan. Founded in 1996 as the Nanhua College of Management, it was elevated to university status in 1999. The university was founded by the Buddhist monk Hsing Yun of Fo Guang Shan. It is adjacent to National Chung Cheng University. Wikipedia.

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Deng J.,Nanhua University
The Cochrane database of systematic reviews | Year: 2013

At present, there is a lack of effective treatments for paraquat poisoning. Xuebijing injection is a complex traditional Chinese prescription consisting of Flos Carthami, Radix Paeoniae Rubra, Rhizoma Chuanxiong, Radix Salviae Miltiorrhizae and Radix Angelicae Sinensis. Although clinical experience suggests that Xuebijing injection might have potential in the management of paraquat poisoning, there is no conclusion on the effectiveness of this treatment. To assess the effects of Xuebijing injection in patients with paraquat poisoning. We searched the Cochrane Injuries Group's Specialised Register, the Cochrane Central Register of Controlled Trials (CENTRAL, The Cochrane Library), MEDLINE (OvidSP), EMBASE (OvidSP), CINAHL (EBSCO), ISI Web of Science: Science Citation Index Expanded, ISI Web of Science: Conference Proceedings Citation Index-Science, Chinese bio-medical literature and retrieval system (CBM), China National Knowledge Infrastructure Database (CNKI), and the Traditional Chinese Medicine Database. The search was run on the 29th May 2013. We included all randomised controlled trials (RCTs) comparing Xuebijing injection combined with conventional care against conventional care alone. Two or three authors independently selected studies, assessed study quality and extracted data. We calculated the mortality risk ratio (RR) and 95% confidence interval (CI). Data on all-cause mortality at the end of follow-up were summarised in a meta-analysis. We identified two trials including 84 people. Although there were fewer deaths in people treated with Xuebijing injection, meta-analysis showed that it did not provide a statistically significant benefit in reducing all-cause mortality in people with paraquat poisoning as compared to control (RR 0.71; 95% CI 0.48 to 1.04; P = 0.08). Based on the findings of two small RCTs, Xuebijing injection did not have a statistically significant benefit on reducing all-cause mortality in people with paraquat poisoning. However, both included studies involved small numbers of participants and were considered to be of poor methodological quality. The results are imprecise and easily compatible with the play of chance. Xuebijing injection may be effective for people with paraquat poisoning; however, this needs to be proven by further high-quality evidence.

Chen C.-C.,Nanhua University
Renewable Energy | Year: 2011

This paper presents a framework to evaluate the effectiveness of energy policies and provides a contextual view of measures on energy polices in linking with the objective of a sustainable economy. Firstly, Taiwan's energy policy is overviewed by analyzing the energy-related data to examine its deficit according to the framework presented. This paper finds that the energy policy adopted fails to attain the objective of a sustainable economy because energy consumption and CO2 emissions still keep upward trends. It also concludes that an energy policy should focus on (1) improving energy efficiency, (2) reshaping industry structure and (3) improving energy structure. In other words, the energy policy maker should create an environment that can motivate the development of clean energy supply and utilization for the achievement of energy policy objectives. © 2011 Elsevier Ltd.

Chang P.-C.,Yuan Ze University | Chen S.-H.,Nanhua University
Applied Soft Computing Journal | Year: 2011

This paper deals with an unrelated parallel machine scheduling problem with the objective of minimizing the makespan. There are machine-dependent and job sequence-dependent setup times and all jobs are available at time zero. This is a NP-hard problem and a set of dominance properties are developed including inter-machine (i.e., adjacent and non-adjacent interchange) and intra-machine switching properties as necessary conditions of job sequencing orders in an optimal schedule. As a result, by applying these dominance properties for a given sequence, a near-optimal solution can be derived. In addition, a new meta-heuristic is introduced by integrating the dominance properties with genetic algorithm to further improve the solution quality for larger problems. The performance of this meta-heuristic is evaluated by using benchmark problems from the literature. The intensive experimental results show that GADP can find all optimal solutions for the small problems and outperformed the solutions obtained by the existing heuristics for larger problems. © 2010 Elsevier B.V. All rights reserved.

Chen C.Y.,Nanhua University
Journal of agricultural and food chemistry | Year: 2010

Lonicera japonica (Caprifoliaceae) has been known as an anti-inflammatory herb in traditional Chinese medicine for thousands of years and is used constantly for upper respiratory tract infections. Luteolin, an active flavonoid compound isolated from Lonicera japonica, has a spectrum of biological activities, especially with antioxidative and anti-inflammatory properties. However, whether luteolin has a direct inhibitory effect on lung fibrosis has not been established. In this study, we examined the effects of luteolin on lung fibrosis both in vivo and in vitro. We found that oral administration of luteolin (10 mg/kg) efficiently suppressed the neutrophil infiltration as well as TNF-α and IL-6 elevation in the bronchoalveolar lavage fluid in bleomycin-instilled C57BL/6J mice. Luteolin also alleviated collagen deposition, TGF-β1 expression, and lung fibrosis upon bleomycin instillation. A similar tendency was observed in both early and delayed luteolin-treated groups. Next, our in vitro studies showed that luteolin inhibited TGF-β1-induced α-SMA, type I collagen, and vimentin expression in primary cultured mouse lung fibroblasts. Moreover, luteolin significantly blocked TGF-β1-mediated epithelial marker (E-cadherin) downregulation and mesenchymal cell markers (fibronectin and vimentin) upregulation, as well as retaining epithelial morphology in human alveolar epithelial-derived A549 cells. Additionally, luteolin could attenuate TGF-β1-induced Smad3 phosphorylation in both lung fibroblasts and A549 cells. These findings suggest that luteolin has a potent antifibrotic activity; this effect was mediated, at least in part, by inhibition of lung inflammation and suppression of myofibroblast differentiation as well as epithelial-to-mesenchymal transition.

Chen C.C.,Nanhua University
International Journal of Environmental Science and Technology | Year: 2010

The regional inequalities in socio-economical characteristics such as income, population density, age composition, unemployment rate and the education level may bring about variation in waste generation, recycling and collection. Using environmental Kuznets curve, the factors affecting municipal solid waste disposal are examined. The results demonstrate that an inverted N-shaped curve executes on municipal solid waste disposal for all regions. As personal disposable income increases, per capita municipal solid waste disposed firstly declines, then grows at the second stage and finally decreases again. All the explanatory variables including economic factors, social characteristics and geographical barriers are found to influence municipal solid waste disposal significantly. Each person increase in population density leads to an increase in municipal solid waste disposed by approximately 1.17 × 10-4 kg/day. Each percent increase in age composition results in a decrease in municipal solid waste disposed by approximately 0.0224 kg/day; in the unemployment rate causes a decrease of 0.0901 kg/day and in the education level results in a decrease of 0.01556 kg/day. In general, municipal solid waste disposal starts to increase at the first turning point of personal disposable income NT$ 198,000 (about US$ 6,280) and to decrease at the second point of NT$ 389,000 (about US$ 12,350) for all regions (pooled data). The rural regions, however, cannot support the inverted N-shaped curve by the 'reduced form' while urban regions have a significant outcome. This result implies that income can only explain a portion of variation while other social and geographical factors contribute a lot to identify the variation in municipal solid waste disposal between urban and rural regions. © IRSEN, CEERS, IAU.

Chen C.-C.,Nanhua University | Chen Y.-T.,National Taipei University of Nursing and Health Sciences
Resources, Conservation and Recycling | Year: 2013

Whether to recycle the recyclable fraction in the MSW (municipal solid waste) or to incinerate it for energy recovery is a debating issue. In this paper we present a simple criterion to judge what type of waste components should be recycled or incinerated with energy recovery. According to the R1 formula presented by the waste framework directive (Directive 2008/98/EC of the European Parliament), this paper calculates the energy performances of MSW waste-to-energy plants currently operated in Taiwan firstly. By using the assumed value of energy recovery efficiency and carbon emission costs, we compare the treatment methods between recycling (material recovery) and energy recovery by the cost and benefit analysis, and examine the suitability of recycling for waste fractions of paper, food waste, PET, PVC, and plastic bags/films under a variety of scenarios. The results show that food waste is more appropriate to be treated by recycling while plastic bags/films are suggested to be incinerated with energy recovery. © 2013 Elsevier B.V.

Chen C.-C.,Nanhua University
Resources, Conservation and Recycling | Year: 2010

Traditionally, the performance of MSW (municipal solid waste) management is almost assessed based on the recycling rate or the collection cost per unit of waste collected only. It neglects the impact of the different actors in the society on the performance assessment. In this paper, we evaluate the integrated efficiency ofMSWmanagement that is divided into three stages:MSWgeneration, sorting and collection by using the tools of data envelopment analysis (DEA) and analytical hierarchical process (AHP). The relative efficiency in proxy of performance at each stage for each decision making unit (DMU) is calculated byDEAand the weighting factor at each stage in affecting the integrated efficiency ofMSWmanagement is measured through the support of AHP. We compareMSWmanagement performance between urban and rural regions in Taiwan and attempt to examine the factors that affect the efficiency variation, by using data of 23 cities/counties in 2008. The results show that urban regions have higher performance in sorting but lower in generation, collection and integrated efficiency than rural regions. This paper highlights the important role of MSW generation in affecting MSW management performance and provides an integrated model to assess MSW management performance by dividing MSW management into three stages including MSW generation, sorting and collection. © 2010 Elsevier B.V.

Chen Y.-T.,National Taipei University of Nursing and Health Sciences | Chen C.-C.,Nanhua University
Water Resources Management | Year: 2014

As recycling effluent from municipal sewage plants is technically a feasible way, this paper presents a mathematical model to analyze the extent to which effluent should be reclaimed for industrial use and examine the factor affecting reuse of reclaimed water. The resulting data shows that the low price of fresh water leads to reduced use of reclaimed water and impedes the investment of the effluent purification plant. A mandated regulation on the substitution rate of reclaimed water is suggested to impose on the industry. Theoretically, the optimal substitution rate as well as the water quality is determined by maximizing the total social welfare that results from the construction of conveyance channels and effluent purification plants. A case example is employed to derive the optimal substitution rate and water quality of reclaimed water. Through the numerical analysis, an effluent plant for treating 20,000 kl/day effluent with the substitution rate of 21.24 % is selected as the optimal solution. © 2014 Springer Science+Business Media Dordrecht.

Chou J.-S.,Nanhua University
Advances in Multimedia | Year: 2012

Recently, several studies about proxy signature schemes have been conducted. In 2009, Yu et al. proposed an anonymous proxy signature scheme attempting to protect the proxy signer's privacy from outsiders. They claimed that their scheme can make the proxy signer anonymous. However, based on our research, we determined that this was not the case and the proxy signer's privacy was not anonymous. Hence, in this paper, we propose a new anonymous proxy signature scheme that truly makes the proxy signer anonymous while making it more secure and efficient when compared with Yu et al.'s scheme. Our proxy signature scheme consists of two contributions. First, we mainly use random numbers and bilinear pairings to attain the anonymous property. Secondly, we increase the security and efficiency of our proxy in the design. Copyright © 2012 Jue-Sam Chou.

Chen S.-H.,Nanhua University | Chen M.-C.,Wufeng University
International Journal of Production Economics | Year: 2013

Estimation of Distribution Algorithms (EDAs) have recently been recognized as a prominent alternative to traditional evolutionary algorithms due to their increasing popularity. The core of EDAs is a probabilistic model which directly impacts performance of the algorithm. Previous EDAs have used a univariate, bi-variate, or multi-variable probabilistic model each time. However, application of only one probabilistic model may not represent the parental distribution well. This paper advocates the importance of using ensemble probabilistic models in EDAs. We combine the univariate probabilistic model with the bi-variate probabilistic model which learns different population characteristics. To explain how to employ the two probabilistic models, we proposed the Ensemble Self-Guided Genetic Algorithm (eSGGA). The extensive computation results on two NP-hard scheduling problems indicate the advantages of adopting two probabilistic models. Most important of all, eSGGA can avoid the computation effort overhead when compared with other EDAs employing two models. As a result, this paper might point out a next generation approach for EDAs. © 2012 Elsevier B.V. All rights reserved.

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