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Nanchang, China

Nanchang University is a national university located in Nanchang, Jiangxi, China which was established in 1940 as National Chung-cheng University . Nanchang University is listed among the National Key Universities of China. Wikipedia.


Ding Y.,Nanchang University
International Journal of Simulation: Systems, Science and Technology | Year: 2015

A network users matching model based on maximum weight matching of bipartite graph was presented in the paper. In order to avoid the defect of correctly matched users' profiles missing at attribute value exact matching process, relying on schemaless attribute value similarity, first of all the model selected candidate user set from the ones to be identified, and established a bipartite graph with the attribute value of candidate user profiles and that of source user profiles to be matched. The edge weight of the bipartite graph is subject to Dice comparability coefficient of each attribute value. And then obtained the similarity coefficient of comprehensive profiles of the source users and candidate users. If the comprehensive similarity coefficient of candidate user profile is greater than that of similarity threshold of profile, the candidate user profile is matching with that of source user profile through solving the maximum weight matching of bipartite graph. Eventually, through matching calculation of actual database, the results show that the model can carry out correct matching effectively and specifically for network users of different systems. It has conquered model heterogeneous existing among user information attributes. Through comparing with precise matching algorithm based on attribute value, the algorithm presented in the paper has improved 10% and 5% on recalling rate and accuracy rate respectively. © 2016, UK Simulation Society. All rights reserved.


Xu J.,Nanchang University
Nan fang yi ke da xue xue bao = Journal of Southern Medical University | Year: 2012

To investigate the impact of obstructive sleep apnea-hypopnea syndrome (OSAHS) on cerebral microbleeds (CMBs) in patients with cerebral infarction. Consecutive patients with acute cerebral infarction who had cerebral microbleeds shown by susceptibility-weighted imaging (SWI) were enrolled to undergo polysomnography (PSG). The patients were divided into two groups, namely non-OSAHS group with apnea-hypopnea index (AHI) less than 5 and OSAHS group with greater AHI, and the clinical and radiological features of cerebral microbleeds were compared between them. Forty-nine patients were enrolled in this study, including 27 (55.1%) with both cerebral infarction and OSAHS and 22 (44.9%) with cerebral infarction but not OSAHS. A comparison of the risk factors showed that hypertension, a smoking history, and a history of stroke were more prevalent in patients with OSAHS than in those without OSAHS (P<0.05). The incidences of subclinical stroke in OSAHS and non-OSAHS patients were 37.0% (10/27) and 9.0% (2/22) (P<0.05), respectively. Neurological imaging revealed a greater number of cerebral microbleeds in OSAHS group than in non-OSAHS group (P<0.05). In OSAHS patients, 77.8% of the microbleeds were distributed in cortical-subcortical areas, 55.6% in the basal ganglia area, and 25.9% in the infratentorial area, as compared to the percentages of 50.0%, 40.9% and 50.0% in non-OSAHS patients, respectively (P<0.05). In OSAHS patients, 40.7% also had leukoaraiosis, and 48.1% had two or more causes, as compared to the percentages of 13.6% and 18.2% in non-OSAHS patients, respectively (P<0.05). OSAHS can be a risk factor for cerebral microbleeds. Patients with both cerebral infarction and OSAHS tend to have greater and more extensive lesions of cerebral microbleeds, more complicated cause of the disease, and a grater likeliness of stroke recurrence.


In this study, I use the apparent-magnitude-limited Main galaxy sample of the Sloan Digital Sky Survey Data Release 7 and investigate the environmental dependence of all of the five-band luminosities. To decrease the radial selection effect, I divide the whole sample into many subsamples with a redshift binning size of Δz = 0.01 and analyze the environmental dependence of all of the five-band luminosities of subsamples in each redshift bin. It turns out that luminous galaxies in M u (the u-band absolute magnitude) exist preferentially in low-density regions of the universe, while faint galaxies in M u are located preferentially in high-density regions, especially in the redshift range 0.05 ≤ z ≤ 0.10.


Tang X.L.,Nanchang University
Yi chuan = Hereditas / Zhongguo yi chuan xue hui bian ji | Year: 2013

Sterol regulatory element binding protein 1 (SREBP-1) is one of the important nuclear transcription factors. SREBP-1 can maintain lipids dynamic equilibrium by regulating the expression of enzymes required for synthesis of endogenous cholesterol, fatty acids, triglycerides and phospholipids. Anomalies of SREBP-1 and its target genes can cause a series of metabolic diseases such as insulin resistance, type II diabetes, heart dysfunction, vascular complications and hepatic steatosis. In these years, the development of high-throughput technologies has greatly expanded our knowledge about SREBP-1 target genes and the pattern of transcriptional regulation. Here we reviewed recent research progress of SREBP-1, with a focus on the protein structure, activation process, DNA binding sites and target genes. Most importantly, we showed the transcriptional regulatory networks based on omics datasets, which will contribute to a better understanding of the role of SREBP-1 in lipid metabolism and provide new clues for the treatment of lipid metabolism disorders.


This paper studies the globally robustly asymptotical stability in mean square of uncertain stochastic neural networks with discrete interval and distributed time-varying delays. By constructing an augmented Lyapunov-Krasovskii functional, some delay-dependent criteria for the globally robustly asymptotical stability of such systems are formulated in terms of linear matrix inequalities (LMIs). Finally, two numerical examples are provided to illustrate the effectiveness of the obtained results. © 2012 Elsevier B.V.


Zhou W.,Nanchang University
Journal of Cardiothoracic Surgery | Year: 2013

Right-sided aortic arch is a rare anomaly, and aortic dissection involving a right-sided aortic arch is extremely rare. We report the case of a 65-year-old man with a right-sided aortic arch and a right descending aortic dissection and a stent-graft was accurately deployed without perioperative complications. There were no any complaints and complications after 18 months follow-up. The CTA demonstrated that the false lumen was largely thrombosed only with a mild type II endoleak and a mild descending aortic expansion. We feel that endovascular repair is feasible to patient of type B aortic dissection with a right-sided aortic arch. However, long-term clinical efficacy and safety have yet to be confirmed. © 2013 Zhou; licensee BioMed Central Ltd.


Wu F.,Nanchang University
European Physical Journal C | Year: 2015

Applying the background field method, we construct by explicit computation the leading-order nonlocal quantum correction to the on-shell effective action for ϕ3 theory in six dimensions. We then use the resulting action to obtain the nonlocal correction to the energy-momentum tensor. At leading order, we find that this nonlocal correction modifies the virial current when the scalar field is minimally coupled to gravity. This is to be compared to the classically Weyl invariant case, where it only corrects the traceless part of the energy-momentum tensor. © 2015, The Author(s).


Wang Y.,Nanchang University | Si Y.,Qinghai University | Leung H.,University of Calgary
IEEE Transactions on Vehicular Technology | Year: 2010

A novel coverage-prediction method for outdoor radio propagation based on the inversion theory is proposed here. Coverage prediction in a wireless cellular network is treated as an inverse problem instead of using high-precision geometric modeling. More precisely, the problem is solved by an inversion of the measured data under some a priori constraints, and the complicated propagation-prediction problem is reduced to solving a system of large-scale ill-condition equations. The effectiveness of the proposed method is demonstrated by using experiments under various radio environments in Guangdong, China. The prediction results are approximately consistent with independent checking samples, and the proposed strategy is compared with other existing approaches. © 2009 IEEE.


Wang X.,Harbin Institute of Technology | Ni W.,Nanchang University
IEEE Transactions on Systems, Man, and Cybernetics, Part B: Cybernetics | Year: 2012

In this paper, the leader-following formation problem of multirobot systems with switching interconnection topologies is considered. The robots are required to move in a formation with formation constrains described in terms of relative distances of the robots and the formation (as whole entity) is required to track the trajectory generated by an exosystem. The exosystem of the considered multirobot systems provides driving forces or environmental disturbance, whose dynamics is different from the dynamics of the robots. A systematic distributed design approach for the leader-following formation problem is proposed via dynamic output feedback with the help of canonical internal model. © 2012 IEEE.


Xiao S.-B.,Nanchang University
Applied Mechanics and Materials | Year: 2014

Traffic jams increasingly threaten the normal city traffic, so our paper analyzes the state of the existing road traffic congestion, road traffic congestion found in the state is a relatively vague and random dynamic data model. Based on these two characteristics, we propose a road traffic congestion degree assessment model based on Bayesian algorithm. Based on the theoretical analysis of Bayesian algorithms to improve the processing efficiency of the algorithm to construct the road traffic congestion degree evaluation model based on Bayesian algorithm set, and the simulation experiments. © (2014) Trans Tech Publications, Switzerland.


Cheng X.,Nanchang University
Cardiovascular Therapeutics | Year: 2013

Hyperhomocysteinemia (Hhcy) was defined as an independent risk factor for cardiovascular events. A number of clinical trials had investigated the relationship between Hhcy lowering treatment and cardiovascular diseases, however, the results of these studies remain controversial. This review article gave an over view of the homocysteine metabolisms and updated the recently published results in the role of Hhcy lowering therapy on cardiovascular events. © 2012 John Wiley & Sons Ltd.


Peng G.,Nanchang University
Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery | Year: 2012

To investigate the feasibility and necessity of No.13 lymph node dissection for advanced gastric carcinoma. Clinical data of 144 cases who were diagnosed as TNMII-III stage gastric carcinoma were collected from January 2007 to December 2009 in the Department of General Surgery at the First Affiliated Hospital of Nanchang University. Seventy-two cases who received D2 radical gastrectomy plus No.13 lymph node dissection were selected as the study group, and they were matched 1:1 to 72 cases who received D2 Radical gastrectomy (the control group) for TNMII-III stage gastric carcinoma. The differences in the intraoperative and postoperative parameters and survival time were compared, and the factors associated with No.13 lymph node metastasis were analyzed. There were no significant differences between the two groups in operative time [(2.8 ± 0.4) h vs. (2.7 ± 0.4) h], blood loss [(191.9 ± 81.5) ml vs. (186.0 ± 81.7) ml], the incidence of postoperative complications (18.1% vs. 15.3%), length of hospital stay [(12.3 ± 4.2) d vs. (11.9 ± 3.2) d] and 3-year survival rate (63% vs. 57%) (all P>0.05). In the study group, there were 15 patients (20.8%) with positive No.13 lymph nodes, and the 3-year survival rate was 13%, significantly lower compared to those with negative No.13 lymph node (73%, n=57) (P<0.05). Multivariate analysis showed that N stage (P<0.01) and histological type (P<0.05) were independently associated with No.13 lymph node metastasis. No.13 lymph node dissection for TNMII-III stage gastric cancer is feasible and necessary.


Lai Z.-H.,Nanchang University | Leng Y.-G.,Tianjin University
Mechanical Systems and Signal Processing | Year: 2016

Stochastic resonance (SR) is an important approach to detect weak vibration signals from heavy background noise and further realize mechanical incipient fault diagnosis. The stochastic resonance of a bistable Duffing oscillator is limited by strict small-parameter conditions, i.e., SR can only take place under small values of signal parameters (signal amplitude, frequency, and noise intensity). We propose a method to treat the large-parameter SR for this oscillator. The linear amplitude-transformed, time/frequency scale-transformed, and parameter-adjusted methods are presented and used to produce SR for signals with large-amplitude, large-frequency and/or large-intensity noise. Furthermore, we propose the weak-signal detection approach based on large-parameter SR in the oscillator. Finally, we employ two practical examples to demonstrate the feasibility of the proposed approach in incipient fault diagnosis. © 2016 Elsevier Ltd.


Zhang C.,Shandong University of Science and Technology | Chen P.,Shandong University of Science and Technology | Liu Y.,Shandong University of Science and Technology | Sun S.,Shandong University of Science and Technology | Peng D.,Nanchang University
Renewable Energy | Year: 2015

Thermal performance of vertical U-pipe borehole heat exchanger (BHE) is an important research subject for the design and application of ground-coupled heat pump system (GCHPs). This paper presents an improved evaluation method for thermal performance of BHE based on analytical solution model, which is validated by comparing with duct storage system (DST) model and field experiment. Using the evaluation method, impacts of inlet fluid temperature, fluid flow rate and borehole depth on thermal performance of two types of U-pipe BHEs are studied. The study provides a good alternative of the experimental method for thermal performance test (TPT) and a useful thermal performance evaluation tool for BHEs in GCHPs. © 2014 Elsevier Ltd.


Zou W.-N.,Nanchang University | Zou W.-N.,University of Akron | Pan E.,Zhengzhou University | Pan E.,University of Akron
International Journal of Solids and Structures | Year: 2012

We solve analytically the Eshelby's problem in an anisotropic multiferroic bimaterial plane. The solution is based on the extended Stroh formalism of complex variables, and is valid for the inclusion of arbitrary shapes, described by a Laurent polynomial, a polygon, or the one bounded by a Jordan curve. Furthermore, the results in the corresponding half plane and full plane can be reduced directly from the bimaterial-plane solution. As such, the solution unifies the complex variable method and the Green's function method, extending further to the multiferroic bimaterial plane of general anisotropy. The essential eigenfunctions are also identified by which the induced fields can be simply determined. Numerical results are presented to investigate the features of these eigenfunctions as well as the strain, electric and magnetic fields (components of the extended Eshelby tensor). Particularly, we present the values of these fields at the center of the N-side regular polygonal inclusion and also the average values of these fields over the inclusion area. The effect of the half-plane traction-free surface condition as well as the effect of various couplings on the induced fields is discussed in detail. For the N-side regular polygonal inclusion, it is found that, when the inclusion is in the full plane, both the center and average values of the Eshelby tensor are independent of the side number N, except for N = 4. We further show that the piezoelectric and piezomagnetic coupling coefficients could significantly affect the Eshelby tensor. These features should be useful in controlling the Eshelby tensor for the design of better multiferroic composites. Typical contours of the field quantities in and around the inclusion bounded by both straight and curved line segments in a multiferroic bimaterial plane are also presented. © 2012 Elsevier Ltd. All rights reserved.


Guo G.H.,Nanchang University
Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns | Year: 2016

In recent years, growth in number of mass burn casualties accompanied by large number of deaths, has increased, such as dust blast occurred in Kunshan in 2014 and explosion of chemicals occurred in Tianjin in 2015. These disasters made us aware that our knowledge of care of mass burn casualties must be renewed, and therapeutic strategies currently practiced in ICU should be adopted. This paper introduces the concept of critical burn and provides reference on how to carry out fluid resuscitation, early enteral nutrition, mechanical ventilation, continuous renal replacement therapy, wound management, as well as infection control, etc.


Peng B.,Jiangxi Normal University | Wu D.,Nanchang University
Fuel | Year: 2015

Modes of occurrence of Br in bituminous coal from China were extracted using sequential chemical extraction; coal combustion was simulated with a tube furnace, and the effects and mechanisms of combustion temperature, combustion time, O2 flow rate and water vapor access on the Br release from bituminous coal were investigated. The results showed that the Br release rate increased with the increase of temperature, and 500-900 °C was the main stage of Br release. The Br occurred as water-soluble, ion exchangeable and organic fraction may be completely emitted before 700 °C, bound to carbonate and Fe-Mn oxide may be mainly emitted in 700-900 °C, and occurred in residual fraction which cannot be extracted using sequential chemical extraction can be largely emitted during combustion. Moreover, the Br release rate in bituminous coal increased with the increase of combustion time and O2 flow rate, and more than 97% Br may be emitted at the given experimental condition of combustion temperature of 1000 °C, water vapor access, O2 flow rate of 90 mL min-1 and combustion time of 20 min. During combustion, the Br in bituminous coal was transformed into HBr and easily taken out of the furnace with the help of water vapor, which indicated water vapor can obviously promote the Br release. The additive of SiO2 can capture the Br effectively in the process of the coal combustion. © 2015 Elsevier Ltd. All rights reserved.


Peng D.,Nanchang University | Zhang X.,Nanjing Southeast University
International Journal of Refrigeration | Year: 2015

Solar liquid collector/regenerator (C/R), combining the functions of solar collector and regenerator of absorbent solution together, can be effectively utilized in solar energy-driven liquid desiccant cooling systems. Based on thermal balance of the glazing of solar C/R, a group of modified heat and mass transfer models, validated by experimental results to reflect solution regeneration process more truly, were put forward in this paper. Numerical simulation showed only preheating air stream, keeping an equal humidity ratio, did raise the performance of solar C/R, but preheating solution increased the regeneration efficiencies to reach twice that of preheating air stream. There occurred optimum mass flow rates for both air stream and solution film reaching 36-48 kg m-1 h-1 and 4∼6 kg m-1 h-1 respectively for solar C/Rs of 3∼6 m long. As for effect of the length of solar C/Rs, the regeneration efficiency ηr reached a maximum value at about 4 m and shorter or longer solar C/Rs failed to increase solution regeneration efficiencies. © 2014 Elsevier Ltd and IIR. All Right Reserved.


Huang M.,Nanchang University | Man C.-S.,University of Kentucky
International Journal of Mechanical Sciences | Year: 2016

The capability to accommodate the "Woodthorpe-Pearce 'anomalous' behavior" has often been used as a criterion to judge the flexibility of yield functions for sheet metals. For metals which exhibit neither sharp yield points nor perfectly plastic behavior, the meaning of this term becomes ambiguous in common usage; instead, we employ it to refer to what Woodthorpe and Pearce [3] observed and failed to predict in their study on aluminum sheets with average r-value <1, namely: In tension tests the balanced biaxial flow curve always lies above the average uniaxial flow curve in a common figure where the horizontal axis denotes the balanced biaxial true-strain and the uniaxial true-strain for the two curves, respectively. In this paper, using the generalized Hershey-Hosford yield function with isotropic strain hardening, we show that the balanced biaxial flow curves in Woodthorpe and Pearces experiments can be predicted from their corresponding average uniaxial flow curves. Moreover, our analysis and other examples suggest that the aforementioned "anomaly" coined by Woodthorpe and Pearce should be quite common. © 2016 Elsevier Ltd. All rights reserved.


Jin X.,Nanchang University
Frontiers in bioscience (Scholar edition) | Year: 2011

Folliculogenesis is a complex process involving dramatic morphological and functional changes in granulosa and theca cells. This process is sequential and dictated specifically by tightly regulated response to endocrine hormones and intra-ovarian regulators. In mammalian ovaries, only a few number of presented follicles in a fetal ovary can reach ovulatory status during follicular development; more than 99% of the follicles in the ovary undergo a degenerative process known as "atresia" induced by apotosis. It is characterized by distinct biochemical and morphological changes such as DNA fragmentation, plasma membrane blebbing and cell volume shrinkage. Apoptosis in ovary is regulated by a number of endocrine, locally produced intracellular mediators in a stage-specific and time-dependent manner. New knowledge of hormones and cell factors which regulate granulosa cell or oocyte apoptosis and their possible signaling pathways underlying intracellular events has made important contributions in advancing our understanding mechanism of follicular atresia.


Hu P.,Nanchang University | He J.,Jiangxi Tourism and Commerce College
International Journal of Theoretical Physics | Year: 2010

By introducing a kind of new quantum state-Photon-added thermo invariant coherent state (PATCS), we discuss its nonclassicality in terms of the negativity of Wigner function (WF) after deriving its analytical expression. It is found that the Wigner function is related to Lagurre-Gaussian function. We then study the effect of decoherence (a thermal environment) on the PATCS according to its WF (also related to Lagurre-Gaussian function). It is shown that it is not possible for WF to present the negative region when the decay time κt > 1/2 In =. © Springer Science+Business Media, LLC 2009.


Zhang R.,Nanchang University | Chiang W.-C.,University of Tulsa | Wu C.,Tsinghua University
International Journal of Production Economics | Year: 2014

In this paper, we focus on the relationship between operations-based variables (specifically, production speed, scrap rate and maintenance speed) and the manufacturing cost. These variables usually produce opposite influences on the variable cost and the fixed cost. For example, setting the production speed at a high level is beneficial for reducing the variable cost. However, maintaining the high speed incurs considerable fixed costs at the same time. Therefore, an optimization approach is necessary to determine the optimal values of the operational variables for minimizing the average cost. First, a discrete-event simulation procedure is designed for describing the stochastic production environment and for evaluating the settings. Then, an optimization approach based on the ordinal optimization (OO) philosophy and particle swarm optimization (PSO) is used to search in the continuous space of the operational variables. In this process, the optimal computing budget allocation technique is applied so as to fully utilize the computational resource and potentially save the computational time. Finally, numeric computations are conducted for verifying the effectiveness of the proposed algorithm. Sensitivity analysis and discussions are also presented. © 2013 Elsevier B.V.


Pu W.D.,Southwest University | Zhang L.,Southwest University | Zhang L.,Nanchang University | Huang C.Z.,Southwest University
Analytical Methods | Year: 2012

Because of its rich π electrons, graphene oxide (GO) can bind with single-stranded DNA (ssDNA) through π-π stacking, but it cannot bind with double-stranded DNA (dsDNA). This different binding ability of GO with DNA has found many applications. By combining this ability with aptamer chemistry, we have developed a highly selective method for the detection of adenosine triphosphate (ATP). The hybrid of ATP aptamer with fluorescein (FAM)-labelled complementary DNA (FAM-DNA) demonstrates a weak affinity for GO and strong fluorescence of FAM-DNA. If ATP is present the strong fluorescence of FAM-DNA is quenched, because the binding of ATP with its aptamer greatly inhibits hybridization of the aptamer with FAM-DNA, and the unhybridized FAM-DNA is adsorbed on to the surface of GO. The quenched fluorescence intensity was found to be in proportion to the concentration of ATP in the range 3-320 μM with a detection limit of 0.45 μM. This method of ATP detection is highly selective and the existence of GTP, CTP and UTP have scarcely effect the determination. © 2012 The Royal Society of Chemistry.


Gong X.,Nanchang University
Journal of Systems Science and Complexity | Year: 2015

This paper establishes some sufficient conditions for the lower semicontinuity of the efficient solution mapping for the semi-infinite vector optimization problem with perturbations of both the objective function and the constraint set in normed linear spaces. The constraint set is the set of weakly efficient solutions of vector equilibrium problem, and perturbed by the perturbation of the criterion mapping to the vector equilibrium problem. © 2015 Institute of Systems Science, Academy of Mathematics and Systems Science, CAS and Springer-Verlag Berlin Heidelberg


Lin K.,Zhejiang University of Technology | Lin K.,University of Sao Paulo | Shu F.-W.,Nanchang University | Wang A.,Zhejiang University of Technology | And 2 more authors.
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2015

In this paper, we present all [(d+1)+1]-dimensional static diagonal vacuum solutions of the nonprojectable Hořava-Lifshitz gravity in the IR limit and show that they give rise to very rich Lifshitz-type structures, depending on the choice of the free parameters of the solutions. These include the Lifshitz space-times with or without hyperscaling violation, Lifshitz solitons, and black holes. Remarkably, even the theory breaks explicitly the Lorentz symmetry and allows generically instantaneous propagations, universal horizons still exist, which serve as one-way membranes for signals moving with any large velocities. In particular, particles even with infinitely large velocities would just move around on these boundaries and would not be able to escape to infinity. Another remarkable feature appearing in the Lifshitz-type space-times is that the dynamical exponent z can take its values only in the ranges 1≤z<2 for d≥3 and 1≤z<∞ for d=2, due to the stability and ghost-free conditions of the theory. © 2015 American Physical Society.


Zuo P.,Chinese Academy of Sciences | Feng X.,Chinese Academy of Sciences | Xie Y.,PLA University of Science and Technology | Wang Y.,Chinese Academy of Sciences | And 2 more authors.
Astrophysical Journal | Year: 2015

Dynamic pressure pulses (DPPs) in the solar wind are a significant phenomenon closely related to the solar-terrestrial connection and physical processes of solar wind dynamics. In order to automatically identify DPPs from solar wind measurements, we develop a procedure with a three-step detection algorithm that is able to rapidly select DPPs from the plasma data stream and simultaneously define the transition region where large dynamic pressure variations occur and demarcate the upstream and downstream region by selecting the relatively quiet status before and after the abrupt change in dynamic pressure. To demonstrate the usefulness, efficiency, and accuracy of this procedure, we have applied it to the Wind observations from 1996 to 2008 by successfully obtaining the DPPs. The procedure can also be applied to other solar wind spacecraft observation data sets with different time resolutions. © 2015. The American Astronomical Society. All rights reserved..


Wang M.,Nanchang University
Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery | Year: 2010

To evaluate the efficacy and safety of vasodilators for sudden sensorineural hearing loss. Based on the principles and methods of Cocharne Systematic Reviews, we searched the cochrane central register of controlled trials, PubMed, Embase, ISI, the China biological medicine datebase, VIP, CNKI and Wangfang database. Randomized controlled trials about using vasodilators to treat sudden sensorineural hearing loss were included. Meta-analysis was performed for the results of homogeneous studies using RevMan software. Twenty eight randomized control trials met the inclusion criteria. Seven studies showed vasodilators was not more effective than placebo. From 14 studies comparing vasodilators with vasodilators and 9 studies comparing vasodilators with other drugs, no definite conclusion could be drawn. The evidence currently available does not support the use of vasodilators in the treatment of sudden sensorineural hearing loss. Further randomized, double-blind, placebo-controlled trials are needed in order to define the efficacy and acceptability of vasodilators in the treatment of sudden sensorineural hearing loss.


Faming Z.,Nanchang University
Journal of Convergence Information Technology | Year: 2012

Previous studies of operating performance of listed companies usually adopt static comprehensive evaluation method but not dynamic evaluation method. Besides, the evaluation information is aggregated in a simple weighted method, without integration of management tool. Considering these two deficiencies, this paper puts forward a dynamic incentive evaluation model and applies it in the comprehensive evaluation of the operating performance of listed companies. The paper first introduces dynamic incentive evaluation model, and then carries out an empirical study, using the annual reports data (2005-2009) of 13 refrigeration and air-conditioning industry listed companies. The results indicate that, compared with the evaluation results of traditional static method and dynamic method, the evaluation results of dynamic incentive model can reflect the operating performance of listed companies more objectively and comprehensively. Thus this model achieves good evaluation effect and has practical value.


Wang C.,Nanchang University
Energy Education Science and Technology Part A: Energy Science and Research | Year: 2014

In view of stress problems on dam heel of gravity dam for which no final conclusion is reached at present, by studying the existing approximate method, a new approximate method of dam heel stress isproposed. This method not only can reflect stress concentration on dam heel area, but also reflect static balance conditions of structure with clear concept, simple calculation, and certain utility value. © Sila Science. All Rights Reserved.


Deng X.-F.,Nanchang University
Bulletin of the Astronomical Society of India | Year: 2014

Using two volume-limited Main galaxy samples of the Sloan Digital Sky Survey Data Release 10 (SDSS DR10), I investigate the environmental dependence of galaxy age, and get the same conclusions in two volume-limited Main galaxy samples: old galaxies exist preferentially in the densest regions of the universe, while young galaxies are located preferentially in low density regions. Such an age-density relation is likely a combination of a strong age-stellar mass relation and the stellar mass-density relation. © 2014, Astronomical Society of India, Indian Institute of Astrophysics. All rights reserved.


Lu X.Y.,Nanchang University
Zhonghua nan ke xue = National journal of andrology | Year: 2010

Stimulated by retinoic acid gene 8 (STRA8) is specifically expressed in mammalian germ cells before their transition from mitosis to meiosis. STRA8 expression is observed only in the postnatal testis. Single nucleotide polymorphisms but no mutations were identified in the coding or proximal promoter region of STRA8 in some gonadal dysgenesis patients. Studies on the teratocarcinoma cells and embryonic stem cells (ESC) transfected with STRA8-EGFP, a fusion construct harboring the promoter and coding region of the enhanced green fluorescence protein, have shown that the STRA8-EGFP positive cells may undergo meiosis, develop into sperm and generate live offspring mice. STRA8-EGFP positive cells derived from the bone marrow are able to differentiate into spermatogenic cells, but arrest in the premeiotic stage, and those from the adult mouse testis, when cultured in ESC culture conditions, may acquire ESC properties, pluripotency and redifferentiation capacity and act as a new stem cell source for tissue regeneration. The presence of oocytes renewed in postnatal mouse ovaries calls in question the absence of STRA8 in postnatal mouse ovaries.


Tian C.,University of Chinese Academy of Sciences | Zou S.,Nanchang University | Hu B.,University of Chinese Academy of Sciences
Investigative Ophthalmology and Visual Science | Year: 2016

PURPOSE. There is no myelination in most mammalian retinas, and if it does happen, it is always accompanied by eye disease. Although lower vertebrates are born with myelin, the precise temporal dynamics of myelination in which oligodendrocytes (OLs) are involved, the origin of OLs, their behaviors in myelination, and their function in retinas have not yet been clearly elaborated. Therefore, we focus on these aspects to study the oligodendrocytes and myelin sheath in the zebrafish retina. METHODS. Retinal whole mount, immunohistochemistry, and optic nerve retrograde labeling were performed to monitor the myelination. Taking advantage of whole eye eversion and transplantation techniques, we studied the retinal origin of OLs. By optic nerve transplantation, we can observe single OLs in zebrafish retina. The optokinetic reflex (OKR) behavior test and the lysophosphatidylcholine (LPC)-induced retinal demyelination model were used to test the function of the myelin. RESULTS. First, we demonstrated that myelination starts at 28 dpf in zebrafish retinas. Second, we directly proved that all the OLs in zebrafish retinas migrated from the optic nerve rather than from a domestic source. Third, we found that compared with adult OLs, younger OLs tend to generate longer but a fewer number of internodes. Finally, we found that the myelin in zebrafish eyes is functionally relevant to the elegant OKR. CONCLUSIONS. Our data suggest that the extraocular source of OLs first appeared at 28 dpf in zebrafish retina and then gradually developed with age, which contribute to optokinetic responses. © 2016, Association for Research in Vision and Ophthalmology Inc. All rights reserved.


Chen J.Y.,Nanchang University
Advanced Materials Research | Year: 2014

In the past several decades,ceramic has been serving as a kind of traditional material which is wildly used in high-tech areas such as industry,electronics,military,etc. This essay aims to study the re-design of ceramic products. It starts with the introduction of ceramic characteristics and makes a detail discussion combined with Chinese thousands of years of cultural accumulation. This essay emphasizes the significance of ceramic re-design from three main aspects: the quality of special ceramic material, cultural characteristics and economic characteristics of ceramic. Meanwhile,it makes a point through analyzing the typical re-design cases thoroughly. Ceramic product re-design can not only revitalize current ceramic industry effectively,but also greatly increase the economic benefits. Consequently,"Design in China" is bound to infuse fresh vigor and vitality into ceramic industry. © (2014) Trans Tech Publications, Switzerland.


Xiaobin L.,Nanchang University
RISTI - Revista Iberica de Sistemas e Tecnologias de Informacao | Year: 2016

with the rapid development of the network, the advantage of e-commerce business is becoming more and more obvious, and it has become a popular choice for college students. E-commerce provides a practical platform and development space for college students' Entrepreneur/ship under the influence of modern economic values. On the basis of the composition elements analysis of the campus business platform, the service model of the entrepreneurial platform was built based on the theory of adaptive structure, and the new model of campus e-commerce business platform service was established. Design and implementation of each layer of the system platform based on MVC mode was carried out. Construction of the three layer of the realization of the strategy was put forward, and which is a reasonable solution to the security of system data storage and transmission. The campus e-commerce business platform which is special and in line with the campus environment was put forward and make students realize the business practice of the platform has a real feasibility. The college students e-commerce business platform has a great role in promoting for college students to build e-commerce business platform.


Xu G.,Nanchang University | Yang Z.-T.,South China University of Technology | Long G.-D.,Huawei
International Journal of Advanced Manufacturing Technology | Year: 2012

Determining optimal process parameter settings critically influences productivity, quality, and cost of production in the plastic injection molding industry. Selecting the proper process conditions for the injection molding process is treated as a multi-objective optimization problem, where different objectives, such as minimizing product weight, volumetric shrinkage, or flash present trade-off behaviors. As such, various optima may exist in the objective space. This paper presents the development of an experiment-based optimization system for the process parameter optimization of multiple-input multiple-output plastic injection molding process. The development integrates Taguchi's parameter design method, neural networks based on PSO (PSONN model), multi-objective particle swarm optimization algorithm, engineering optimization concepts, and automatically search for the Pareto-optimal solutions for different objectives. According to the illustrative applications, the research results indicate that the proposed approach can effectively help engineers identify optimal process conditions and achieve competitive advantages of product quality and costs. © 2011 Springer-Verlag London Limited.


Huang M.,Nanchang University | Man C.-S.,University of Kentucky
International Journal of Plasticity | Year: 2013

We consider rolled sheets of cubic metals which are macroscopically orthorhombic and microscopically aggregates of tiny crystallites. The preferred orientations of the crystallites create crystallographic texture, which is a main cause for the plastic anisotropy of the sheet metal. Crystallographic texture is characterized by the orientation distribution function or, equivalently, the texture coefficients. In this paper we propose, for weakly textured sheets of cubic metals, a new generalization of the Hosford yield criterion, which is applicable for any state of stress and, as a distinguishing feature, incorporates explicitly the effects of crystallographic texture on plastic anisotropy. Besides the principal stresses, our new yield function depends on the principal stress directions, certain texture coefficients (which can be measured by X-ray diffraction or electron backscatter diffraction), and three material parameters, namely the exponent η, the uniaxial yield stress Yiso for the isotropic polycrystal, and a parameter β which describes the strength of the effects of crystallographic texture. We derive formulas with which the three material parameters can be calibrated by uniaxial and/or balanced biaxial tension tests. As examples, the three material parameters are calibrated against (i) the predictions of the Taylor model in uniaxial and balanced biaxial tension tests and (ii) experimental data on directional dependence of the q-value and uniaxial yield stress that pertain to two aluminum alloys. The values of the exponent η determined by calibration with the Taylor model are approximately 10 and 6.6 for FCC and BCC sheet metals, respectively, which square well with the earlier findings of Hosford and coworkers. For the two aluminum alloys studied, it is found that both the plastic anisotropy of the q-value and of the uniaxial yield stress can be described reasonably well by the new yield criterion. © 2012 Elsevier Ltd. All rights reserved.


Zhao J.,Shaoxing University | Xiong J.,Nanchang University
Chinese Journal of Lung Cancer | Year: 2015

Adenocarcinoma and squamous cell carcinoma are the most common histological types of non-small cell lung cancer (NSCLC). Several molecular alterations have been defined as "driver oncogenes" responsible for both the initiation and maintenance of the malignancy. With next-generation sequencing (NGS) which having multiple and high-throughput genotyping is wildly used and promoted, make the detection of patients gene composition from a tiny tumor biopsy specimens become possible, initiate the clinical studies based on the genetic characteristics, and promote the progress of molecular typing in NSCLC. So far, about 60% of lung adenocarcinoma has been found harbouring driver oncogenes, the rate of lung squamous cell carcinoma driven genes detection has gradually improved, in which epidermal growth factor receptor (EGFR), anaplastic lymphoma kinase (ALK), fibroblast growth factor receptor 1 (FGFRl), phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) and so on plays important roles. The currently effective targeted therapies is mainly used against EGFR, ALK, etc. In this review, we will report the mainly advances on some latest driver mutations of NSCLC. © 2015 Chinese Journal of Lung Cancer. All Rights reserved.


Yue W.-X.,Nanchang University
Gongcheng Lixue/Engineering Mechanics | Year: 2014

Sheets would be cracked during their deep drawing. In order to solve this problem, many scholars are mainly devoted to changing the blank-holder force to control the cracks in their published literatures. The paper introduces a texture coefficient and uses elastic-plastic mechanics and the relation between the material coefficient and the texture coefficient of Hill yield criterion to the relation between the texture coefficient and thickness increment during the deep drawing. Then the paper proves the relation through examples, we can reduce the possibility of crack occurrence during the deep drawing by changing the texture coefficient.


Ying M.,Nanchang University | Chen D.,CAS Institute of Zoology
Development Growth and Differentiation | Year: 2012

Tudor domain-containing proteins (Tudor proteins), which recognize and bind to methyl-arginine/lysine residues, play important roles in diverse epigenetics, gene expression and the regulation of various small RNAs. Using the complete set of 23 Tudor proteins from Drosophila, together with the available functional information, we propose a putative link for different types of Tudor domains (histone-binding, SMN and SND1) and the four functional groups of Tudor proteins (Group 1, binding the methyl-lysine/arginine of histone tails; Group 2, binding the methyl-RG/RA box of ligand; Group 3, binding the methyl-RG/RA box of microRNPs; and Group 4, binding the methyl-RG/RA box of PIWI proteins). Tudor domain types are distinguished by the nature of the sequence flanking the canonical Tudor domains. Sequence analysis indicates that Tudor domains experienced stepwise transit from one type to another during evolution. Tudor proteins of Group 4, collectively representing the great majority of Tudor proteins in Drosophila, are characterized by multiple Tudor domain repeats, which might be required for associating with several molecules of the same germ granule components. Tudor domain, a segment of approximately 60 amino acid residues, has been found in fungi, protozoa, unicellular eukaryota, plants and metazoa but not in the Guillardia theta nucleomorph. Similar frequencies of Tudor-containing genes (Tudor genes) among vertebrates and the frequent occurrence of orthologues among vertebrates, along with similar observations within arthropods suggest that Tudor genes are inherited largely vertically during evolution within different phylogenetic lineages. © 2012 The Authors. Development, Growth & Differentiation © 2012 Japanese Society of Developmental Biologists.


Song X.,Linyi Normal University | Xu S.,Linyi Normal University | Chen L.,CAS Yantai Institute of Coastal Zone Research | Wei Y.,China Pharmaceutical University | Xiong H.,Nanchang University
Journal of Applied Polymer Science | Year: 2014

Food security as a world issue has received increasing concern, and therefore, effective analytical methods and technologies have been continuously developed. However, the matrix complexity of food samples and the trace/ultratrace presence of targeted analytes require highly efficient cleanup and enrichment materials and procedures. Molecularly imprinted polymers (MIPs) with specific recognition abilities as versatile materials are being increasingly developed for diverse species in various fields, especially in food analysis. In this review, we mainly summarize the recent advances in MIPs used for food matrices over the last 5 years. We focus on toxic and harmful substances, such as pesticide/drug residues, heavy metals, microbial toxins, and additives. Some relatively new preparation methods involving surface imprinting, composites, and stimuli responsiveness are reviewed. Different MIPs as solid-phase adsorbents in solid-phase extraction, solid-phase microextraction, matrix solid-phase dispersion, stirring bar sorptive extraction, and magnetic material extraction and as stationary phases in chromatographic separation for foodstuff have been comprehensively summarized. MIP-based biomimetic sensing and enzymelike catalysis receive special attention. Moreover, some limitations and comparisons related to MIPs performances are also discussed. Finally, some significant attempts to further promote MIP properties and applications to ensure food safety are discussed. © 2014 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2014, 131, 40766. © 2014 Wiley Periodicals, Inc.


Xanthine oxidase (XO) catalyses hypoxanthine and xanthine to uric acid in human metabolism. Overproduction of uric acid will lead to hyperuricemia and finally cause gout and other diseases. Luteolin is one of the major components of celery and green peppers, its inhibitory activity on XO and their interaction mechanism were evaluated by multispectroscopic methods, coupled with molecular simulation. It was found that luteolin reversibly inhibited XO in a competitive manner with inhibition constant (Ki) value of (2.38±0.05)×10(-6) mol l(-1). Luteolin could bind to XO at a single binding site and the binding was driven mainly by hydrophobic interactions. Analysis of synchronous fluorescence and circular dichroism spectra demonstrated that the microenvironment and secondary structure of XO were altered upon interaction with luteolin. The molecular docking results revealed luteolin actually interacted with the primary amino acid residues located within the active site pocket of XO. Copyright © 2013 Elsevier Ltd. All rights reserved.


Deng X.-F.,Nanchang University
Canadian Journal of Physics | Year: 2013

The primary goal of this study is to explore the dependence of the clustering properties of galaxies on star formation rate (SFR) and specific star formation rate (SSFR). From the main galaxy sample of the Sloan Digital Sky Survey Data Release 7, we construct two volume-limited samples with absolute magnitudes above and below Mr, and then divide each volume-limited main galaxy sample into two subsamples with low SFRs and high SFRs or low SSFRs and high SSFRs. A strong dependence of the clustering properties on SFR and SSFR is found: high SFR and SSFR galaxies are preferentially isolated or found in close pairs and small groups, whereas low SFR and SSFR galaxies preferentially inhabit dense groups and clusters. © 2012 Published by NRC Research Press.


From each of two volume-limited main galaxy samples of the Sloan Digital Sky Survey data release 7, a paired galaxy sample and an isolated galaxy sample are constructed and comparative studies between the star formation of galaxies in pairs and isolated are performed to explore influences of galaxy interactions on star formation. It is found that isolated galaxies have an enhancement of the star formation rate and the specific star formation rate, which suggests that interactions between galaxies are not the trigger of enhanced star formation. © 2013 Published by NRC Research Press.


Zhang C.,Shandong University of Science and Technology | Guo Z.,North China University of Water Conservancy and Electric Power | Liu Y.,Shandong University of Science and Technology | Cong X.,Shandong University of Science and Technology | Peng D.,Nanchang University
Renewable and Sustainable Energy Reviews | Year: 2014

With the attractive advantages of high efficiency and environmental friendliness, the ground-coupled heat pump system (GCHPs) has been widely applied in various buildings around the world in recent years, and the knowledge of underground thermal properties is a prerequisite for correct design of GCHPs. As an effective way to obtain thermal properties, thermal response test (TRT) has become a routine tool for the design of larger plants with ground heat exchangers (GHEs). This paper summarizes the specifications for in situ TRT, including test setup, minimum duration, heat input rate etc., analyzes the mathematical models currently available for GHE in TRT, and compares the parameter identification methods which are necessary to obtain reasonable properties according to in situ TRT data. In addition, this paper discusses and summarizes the shortages and imperfects of the current research on TRT and gives some recommendations for future work. © 2014 Published by Elsevier Ltd. All rights reserved.


Xie H.Y.,Nanchang University
Applied Mechanics and Materials | Year: 2014

A big scale data poses a great challenge to data storage, management and data analysis. This article analyzes the basic concepts of large data, and mainly used on large data makes the simple contrast. And paper put forward a platform of regional characteristics based on electronic business information publishing system. Finally the paper gives general model and the realization of the platform structure, key technology and process. The platform uses conversion technology of StrutsCX framework based on J2EE platform and the XSLT parsing template of XML document tree that generates and provide automation platform construction features site for the user, it can quickly set up a tourism industry application component with plug-in manner. © (2014) Trans Tech Publications, Switzerland.


Liu K.,Zhejiang University | Shen L.,Nanchang University | He S.,Zhejiang University | He S.,KTH Royal Institute of Technology
Optics Letters | Year: 2012

We demonstrate that one-way electromagnetic modes could be sustained by the edge of a gyromagnetic photonic crystal slab of triangular lattice under an external dc magnetic field. The applied magnetic field breaks the time-reversal symmetry of the three-dimensional system, and thus the original degeneracy point in k space, at which two dispersion surfaces intersect, is lifted, resulting in a photonic band gap below the light cone. At this band gap, the one-way mode is localized horizontally to the slab edge, while confined by the index contrast in the vertical direction. © 2012 Optical Society of America.


Liu W.,Tongji University | Chen H.,Tongji University | Lai Z.,Nanchang University
Optics Letters | Year: 2012

We report that a narrow guided-mode resonance (GMR) filter with high-index substrate can be achieved by introducing an added layer on the substrate. For this type of GMR filter, the refractive index and thickness of the added layer are the critical parameters for the GMR effect to occur. We demonstrate that this filter has good fabrication tolerances for the grating thickness and fill factor. Our design may promote the application of GMR filters in practice. © 2012 Optical Society of America.


Bai A.,Nanchang University | Bai A.,Beth Israel Deaconess Medical Center | Robson S.,Beth Israel Deaconess Medical Center
Purinergic Signalling | Year: 2015

CD39/ENTPD1 is a prototypic member of the ectonucleoside triphosphate diphosphohydrolase (ENTPDase) family on cell surface. CD39 has been reported to be a marker of regulatory immune cells and catalyzes extracellular hydrolysis of nucleotides to generate AMP and, in tandem with CD73, adenosine. We have recently found in addition that co-expression of CD39 and CD161 by human CD4+ T cells may become a biomarker of human Th17 cells. CD39 and CD161 have direct interactions that are further linked with acid sphingomyelinase (ASM). Upon activation of CD39 and CD161, the molecular interactions boost ASM bio-activity, which generates cellular ceramide to further mediate downstream signals inclusive of STAT3 and mTOR. We suggest modulation of human Th17 responsiveness by CD39 and CD161 and describe novel molecular mechanisms integrating elements of both extracellular nucleotide and sphingolipid homeostasis that are pivotal in the control of human Th17 cells and which could have therapeutic potential. © 2015, Springer Science+Business Media Dordrecht.


Zhang W.,University of Houston | Zhang W.,Nanchang University | Trachootham D.,University of Houston | Trachootham D.,Thammasat University | And 10 more authors.
Nature Cell Biology | Year: 2012

Tissue stromal cells interact with leukaemia cells and profoundly affect their viability and drug sensitivity. Here we show a biochemical mechanism by which bone marrow stromal cells modulate the redox status of chronic lymphocytic leukaemia (CLL) cells and promote cellular survival and drug resistance. Primary CLL cells from patients exhibit a limited ability to transport cystine for glutathione (GSH) synthesis owing to a low expression level of Xc-transporter. In contrast, bone marrow stromal cells effectively import cystine and convert it to cysteine, which is then released into the microenvironment for uptake by CLL cells to promote GSH synthesis. The elevated level of GSH enhances leukaemia cell survival and protects them from drug-induced cytotoxicity. Furthermore, disabling this protective mechanism significantly sensitizes CLL cells to drug treatment in the stromal environment. This stromal-leukaemia interaction is critical for CLL cell survival and represents a key biochemical pathway for effectively targeting leukaemia cells to overcome drug resistance in vivo. © 2012 Macmillan Publishers Limited. All rights reserved.


Yuan K.,Institute of Polymers | Chen L.,Institute of Polymers | Chen Y.,Institute of Polymers | Chen Y.,Nanchang University
Journal of Physical Chemistry B | Year: 2014

Novel PEIE-Ag composites by in situ growth of silver nanoparticles in poly(ethylenimine)-ethoxylated (PEIE) aqueous solution are explored as an efficient interfacial layer for improving inverted polymer solar cells (PSCs) performance. The hybrid PEIE-Ag interfacial material is simple to fabricate only via ultraviolet irradiation with good water-solubility and unique film formation. The generated Ag nanoparticles can anchor in the PEIE polymer chains to form a conductive continuous interpenetrating network structure. Combining of the advantages of PEIE and Ag nanoparticles, the PEIE-Ag shows enhanced charge transport, electron selective and collection, and improved light-harvesting, mainly due to the surface plasmon resonance effect, better energy alignment induced by the formation of ideal dipole layer, as well as the improved conductivity. These distinguished interfacial properties result in the power conversion efficiency of inverted PSCs based on poly[4,8-bis(2-ethyl-hexyl-thiophene-5-yl)-benzo[1,2-b:4,5-b]dithiophene-2,6-diyl]-alt-[2-(2-ethyl-hexanoyl)-thieno[3,4-b]thiophen-4,6-diyl] (PBDTTT-C-T) and [6,6]-phenyl C71-butyric acid methyl ester (PC71BM) photoactive layer substantially improved up to 7.66% from 6.11%. Moreover, the device performance is insensitively dependent on the thickness of the PEIE-Ag interfacial layer, broadening the thicknesses selection window for interfacial materials. These results demonstrate that PEIE-Ag is a potential interfacial material compatible with roll-to-roll techniques and suitable for printed electronic devices. © 2014 American Chemical Society.


Tang Y.,TU Dresden | Tang Y.,Sun Yat Sen University | Jacobi A.,TU Dresden | Vater C.,TU Dresden | And 3 more authors.
Stem Cells | Year: 2015

Reduced tissue levels of endothelial progenitor cells (EPCs) and functional impairment of endothelium are frequently observed in patients with diabetes and cardiovascular disease. The vascular endothelium is specifically sensitive to oxidative stress, and this is one of the mechanisms that causes widespread endothelial dysfunction in most cardiovascular diseases and disorders. Hence attention has increasingly been paid to enhance mobilization and differentiation of EPCs for therapeutic purposes. The aim of this study was to investigate whether Icariin, a natural bioactive component known from traditional Chinese Medicine, can induce angiogenic differentiation and inhibit oxidative stress-induced cell dysfunction in bone marrow-derived EPCs (BM-EPCs), and, if so, through what mechanisms. We observed that treatment of BM-EPCs with Icariin significantly promoted cell migration and capillary tube formation, substantially abrogated hydrogen peroxide (H2O2)-induced apoptotic and autophagic programmed cell death that was linked to the reduced intracellular reactive oxygen species levels and restored mitochondrial membrane potential. Icariin downregulated endothelial nitric oxide synthase 3, as well as nicotinamide-adenine dinucleotide phosphate-oxidase expression upon H2O2 induction. These antiapoptotic and antiautophagic effects of Icariin are possibly mediated by restoring the loss of mammalian target of rapamycin /p70S6K/4EBP1 phosphorylation as well as attenuation of ATF2 and ERK1/2 protein levels after H2O2 treatment. In summary, favorable modulation of the angiogenesis and redox states in BM-EPCs make Icariin a promising proangiogenic agent both enhancing vasculogenesis and protecting against endothelial dysfunction. © 2015 AlphaMed Press.


Long J.,South China University of Technology | Li X.,South China University of Technology | Guo B.,South China University of Technology | Wang L.,South China University of Technology | Zhang N.,Nanchang University
Catalysis Today | Year: 2013

Lignin is one of main components in the most abundant lignocelluloses and is recognized as a unique renewable natural resource for the synthesis of aromatic chemicals. Its isolation and transformation have thereby attracted increasing attention in recent times. Here, an efficient method for the separation of lignin from sugarcane bagasse is reported using acidic ionic liquid catalysts. The structure and physicochemical properties and the molecular weight distribution of the isolated lignin were characterized by FT-IR, 1H NMR and 13C NMR, TG, elemental analysis, UV-vis, SEM and GPC. The results showed that acid functionalized ionic liquids are excellent catalysts for the delignification of sugarcane bagasse: 100% isolation of the desired product was achieved under optimized conditions. © 2012 Elsevier B.V.


Hu B.,Nanchang University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

In this paper we study a parametrized description of neutrino mixing from a phenomenological point of view. We concentrate on the parametrization in terms of higher order corrections to the leading order mixing matrix. A method to describe subleading contributions and their applications to tribimaximal mixing are discussed. We show that mixing matrices similar to tribimaximal-Cabibbo mixing can be obtained by straightforward choices of parameters. To achieve better agreement with the experimental data without increasing the number of free parameters, we impose a simple phenomenological relation from which a trimaximal-like mixing matrix, parametrized by Ue3=sinâ ¡θ13e-iφ, can be derived straightforwardly without imposing additional requirements. It can describe the current global fit to three-neutrino mixing with good accuracy. Its theoretical explanation and phenomenological applications are discussed briefly. © 2013 American Physical Society.


Zhou X.-M.,Nanchang University | Zeng H.-H.,PingXiang College
Faguang Xuebao/Chinese Journal of Luminescence | Year: 2010

Y2O2S: Eu, Si, M(M = Mg, Ca, Sr, Ba) long lasting red luminescence phosphors were synthesized by solid state reaction and analyzed by means of XRD, photoluminescence (PL), thermo luminescence, etc. The results indicate that the strongest emission of both emission spectrum and afterglow spectrum peaks at around 627.0 nm, which is assigned to electric dipole 5D0→ 7F2 transition of Eu 3+, which behaves excellent afterglow property. The doping of alkaline earth ions improves the PL intensity and the afterglow property of the Y2O2S: Eu, Si,M(M=Mg,Ca,Sr,Ba) phosphors.Of all, the Mg-doped sample shows the best property ,the next one is the Ba-doped material.


Hu B.,Nanchang University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2013

In this paper we discuss a new way to derive neutrino mixing patterns, which originates from the idea proposed in a recent article by Hernandez and Smirnov. Its applications to various cases are discussed. We first present the complete set of possible mixing patterns for the minimal case where unbroken residual symmetries of the Majorana neutrino and left-handed charged-lepton mass matrices obey some general assumptions that are also satisfied by many models based on discrete symmetries. We find that they are either well-known mixing patterns or phenomenologically disfavored ones. It shows clearly that, for full-mixing matrices to fit the mixing data with small or negligible corrections, it is necessary to go beyond the minimal scenario. We present an explicit formalism for a rather general nonminimal case. Some applications and phenomenological implications are discussed. Several new mixing patterns are derived. © 2013 American Physical Society.


Liu W.,Tongji University | Li Y.,Tongji University | Jiang H.,Tongji University | Lai Z.,Nanchang University | Chen H.,Tongji University
Optics Letters | Year: 2013

Spectral responses in compound waveguide grating structures composed of two ridges with identical widths in each period are presented. For the proposed structures, we show that the spectral width of the guided-mode resonance (GMR) can be tailored in an independent way without modifying the spectral lineshapes and sideband levels. The method described in this Letter offers a very simple and efficient way to control spectral responses in GMR structures. © 2013 Optical Society of America.


Tang Q.,Linkoping University | Tang Q.,Nanchang University | Solin N.,Linkoping University | Lu J.,Linkoping University | Inganas O.,Linkoping University
Chemical Communications | Year: 2010

Herein we report a method to functionalize in vitro grown insulin amyloid fibrils with various inorganic materials. The counterion of the positively charged amyloid fibril is exchanged with anions from various salts; subsequent addition of appropriate cations results in functionalization of the amyloid fibril. We demonstrate the formation of apatite and platinum complex structures ordered by the amyloid template. © 2010 The Royal Society of Chemistry.


Yang D.,Nanchang University
Key Engineering Materials | Year: 2011

Analytical solutions for potential distributions, velocity distributions of the mixed electroosmotic and pressure-driven flow in rectangular microchannels are discussed. To simulate the flow, a mathematical model, which includes the Poisson-Boltzmann equation and the modified Navier-Stokes equations, is presented and solved using the finite element method based on the Matlab software. The results show that the velocity distribution of mixed flow is compound of the "plug-like" and paraboloid at the steady state, and the pure electroosmotic flow is "plug-like", which is similar with the electric double layer potential profile. The results provide the guidelines for the application of mix driven flow in microfluidic chips. © (2011) Trans Tech Publications.


Zhu T.,Beijing University of Posts and Telecommunications | Wang B.,Beijing University of Posts and Telecommunications | Wu B.,Beijing University of Posts and Telecommunications | Zhu C.,Nanchang University
Expert Systems with Applications | Year: 2011

Understanding the individual behavior has shown to be of paramount importance to the triumph of the telecommunication operators to retain customers, enhance their purchasing capacity, and predict the churn rate. Different behavior patterns can be observed for different groups of users. Hence, there is an interesting problem posted in telecommunication network that how to define the users' role according to their behavior patterns. Traditionally, user behavior characterization methods generally based on their call detail record (CDR), which are user's individual features, are not appropriate to identify the role in network. In this paper, we develop a new methodology for identifying users' role based on their behaviors in telecommunication network using the social features instead of their individual features. Experiments have tested on synthetic data and large real datasets, and reveal good results on both of them. Finally, the methodology is not only limited to call graphs but also apply to other networks for role defining. © 2010 Elsevier Ltd. All rights reserved.


Dong X.,China Pharmaceutical University | Ke X.,China Pharmaceutical University | Liao Z.,Nanchang University
Drug Development and Industrial Pharmacy | Year: 2011

Objective: The aim of this study was to characterize the microstructure of microemulsion consisting of oleic acid, Cremophor RH40, ethanol, and water (Km=2), and investigate the influence of microstructure on the solubilization potential of the microemulsion to meloxicam (MLX). Methods: Pseudo-ternary phase diagrams of microemulsion were constructed using the H2O titration method. The microstructures of microemulsion on dilution line N91 were identified by means of conductivity, viscosity, surface tension, and density. The freeze-fracture electron microscopy proved the specific microstructure. Differential scanning calorimetry (DSC) was used to evaluate the position of MLX in microemulsion, and the solubility of MLX in chosen microemulsions on dilution line N91 was measured. Results: The three microstructures along dilution line N91, including water-in-oil (W/O), bicontinuous (BC), and oil-in-water (O/W) microemulsion, were characterized. The solubilization capacity of W/O microemulsion is the best, compared with the other two, whereas the O/W is the weakest. A possible structure model has been applied for the explanation of difference. Conclusions: The solubilization capacity of microemulsion is closely related with its microstructure. © 2011 Informa Healthcare USA, Inc.


Chen H.,Nanchang University | Zhang Y.,Wuhan University of Science and Technology | Hu P.,Huazhong University of Science and Technology
Neurocomputing | Year: 2010

This paper is concerned with the globally exponential stability in mean square and almost surely exponential stability for neutral stochastic delayed neural networks. By constructing an appropriate Lyapunov-Krasovskii functional and with the help of the semimartingale convergence theorem, some delay-dependent sufficient conditions to guarantee the globally exponential stability in mean square and almost surely exponential stability of such systems are obtained in terms of the linear matrix inequality (LMI), which can be regarded as some less conservative criteria than some existing results when stochastic delayed neural networks of neutral type are designed. Finally, two illustrative numerical examples are given to demonstrate the advantages and applicabilities of the proposed results. © 2010.


Wang Q.,Nanchang University
2nd International Workshop on Education Technology and Computer Science, ETCS 2010 | Year: 2010

Employment competition is fiercer because of global economic crisis. So how to design education program for improving undergraduate competitiveness is focused. Quality Function Deployment (QFD) theory was applied to education program design for satisfying market requirements. First, stakeholder demands from an IE graduate were determined by surveys, and then weighed by Analytic Hierarchy Process (AHP). major stakeholders of Industrial Engineering (IE) education were identified as students, faculty and future employers; in which future employers included enterprise, graduate school and government department according to IE employment situation in China. Second, a set of design requirements including six modules was developed based on the analysis of IE education program in Nanchang University. Furthermore, as an example, enterprise demands were translated into education program with the house of quality, and characters of the other five education programs were showed finally. The designed program satisfies stakeholder requirements well, so that this method can help improve the quality of IE graduate. © 2010 IEEE.


Yan X.,Nanchang University | Yan X.,Fudan University | Cao Z.,Fudan University | Lau C.,Fudan University | Lu J.,Fudan University
Analyst | Year: 2010

We have developed a new aptamer-based chemiluminescence (CL) biosensing platform for the sequential detection of two small molecules as exemplified by adenosine and cocaine. Each biosensing platform comprises NH2- functionalized capture DNA immobilized on magnetic beads; this can hybridize with one end of the aptamer. A corresponding reporter DNA probe labeled with either digoxigenin or biotin on its 5′-terminus recognizes the other end of the aptamer. The target compounds adenosine or cocaine act as specific competitors to aptamer-reporter DNA binding, and the corresponding aptamers preferentially form target-aptamer complexes. This results in detachment of the reporter DNA probe from the magnetic beads, with more target molecules resulting in less reporter DNA probe remaining on the beads. Those left are sequentially detected by using substrate-resolved anti-digoxigenin-alkaline phosphatase and streptavidin-horseradish peroxidase. Experimental results confirm that this CL immunosensing platform has good sensitivity with detection limits of 5.2 × 10-9 M and 3.2 × 10-9 M for adenosine and cocaine, respectively. Because it is straightforward to adapt this strategy to detect a spectrum of small molecules by using different aptamers, this method may offer a new direction in designing high-performance CL aptasensors for sensitive and sequential determination of a limited number of small molecules. © 2010 The Royal Society of Chemistry.


Ren G.,Nanchang University
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2012

To study the chemical constituents of the roots of Dendropanax chevalieri. The constituents were isolated by column chromatography with silica gel, Sephadex LH-20 gel and RP-18. Their structures were elucidated by analysis of spectral data and physicochemical properties. Eight compounds were isolated and identified as palmitic acid (1), dibutylphthalate (2), beta-sitosterol (3), coniferaldehyde (4), scopoletin (5), beta-hydroxypropiovanillone (6), (+)-pinoresinol (7), (+)-syringaresinol (8). Compounds 1-2, 4-8 are obtained from this genus for the first time.


Zhou C.Y.,Nanchang University
Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases | Year: 2011

To observe the expression levels of heat shock protein 70 (hsp70) and NF-kappaB p65 mRNA in lung tissue of acute paraquat (PQ) poisoning rats, and intervention effects of ulinastatin (UTI). Seventy-two Sprague-Dawley (SD) rats were randomly divided into three groups: PQ poisoning group, UTI group and control group. The rats were exposed intragastrically to PQ at the dose of 80 mg/kg to establish a model of the rat acute lung injury. The UTI group was intervened by peritoneal injection with 10000 U/kg UTI in 30 minutes. On the 12, 24, 48, 72 h after exposure, myeloperoxidase (MPO) activity in lung tissue were detected. The expression of the NF-kappaB p65 mRNA and hsp70 mRNA in lung tissue was detected by the reverse transcription-PCR (RT-PCR). The lung pathological changes of rats were observed. The degree of lung injury in PQ group and UTI group was higher than that in control group. But in UTI group the degree of lung injury was lower than PQ group. MPO activity in the lung tissues in PQ group was (31.72 +/- 6.42), (56.23 +/- 8.63), (87.21 +/- 10.02) and (107.21 +/- 13.52) micro/g in 12, 24, 48 and 72 h, respectively which was significantly higher than that [(11.38 +/- 1.25) micro/g] in control group (P < 0.01). MPO activity in the lung tissues in UTI group was (15.65 +/- 3.21), (35.98 +/- 5.74), (59.33 +/- 9.65) and (71.25 +/- 10.58) micro/g in 12, 24, 48 and 72 h, respectively which was significantly lower than those in PQ group (P < 0.01). The expression levels of NF-kappaB p65 mRNA of lung tissues in UTI group in 12, 24, 48 and 72 h were 0.3288 +/- 0.0147, 0.5337 +/- 0.0328, 0.7357 +/- 0.0424 and 0.7547 +/- 0.0905, respectively, which were significantly lower that those (0.4185 +/- 0.0294, 0.8532 +/- 0.0841, 0.9554 +/- 0.0975 and 1.0094 +/- 0.0703) in PQ group (P < 0.01). hsp70 mRNA expression levels in 12, 24, 48 and 72 h of the UTI group were 0.5193 +/- 0.0254, 0.8289 +/- 0.0606, 0.7566 +/- 0.0277 and 0.4873 +/- 0.0105, respectively, which were significantly higher than those (0.3897 +/- 0.0125, 0.5904 +/- 0.0186, 0.4007 +/- 0.0237 and 0.2293 +/- 0.0137) in PQ group (P < 0.01). The expression levels of hsp70 mRNA and NF-kappaB p65 mRNA of rats after intoxication increased significantly. UTI can protect the lung tissues by elevating the expression of hsp70 and reducing the expression of NF-kappaB in the lung tissues of rats with acute paraquat poisoning.


Zhou A.-H.,Nanchang University
Astrophysics and Space Science | Year: 2013

The magnetorotational instability (MRI) in axisymmetric rotating dusty plasmas with viscous effects is investigated by means of a three-component model MRI with a vertical weak magnetic field. Starting from the three-fluid equations and Maxwell's equations, I derive the general linear dispersion relation governing local MRI. The dust rotational flow is assumed to have the same angular velocity as ions and electrons. The dispersion relation of two special cases, without viscosity and dust effects respectively, is discussed in detail by taking into account the high-frequency approximation in order to make the perturbation frequency larger than the ion cyclotron frequency. The numerical results demonstrate that both the viscosity and dust effects can prevent the MRI growth, and the dust-induced effects are shown to be especially significant. © 2012 Springer Science+Business Media B.V.


Deng X.-F.,Nanchang University
Astronomical Journal | Year: 2013

In this study, I apply cluster analysis and perform comparative studies of clustering properties between galaxies and groups of galaxies. It is found that the number of objects N max of the richest system and the maximal length D max of the largest system for groups in all samples are apparently larger than ones for galaxies, and that galaxies preferentially form isolated, paired, and small systems, while groups preferentially form grouped and clustered systems. These results show that groups are more strongly clustered than galaxies, which is consistent with statistical results of the correlation function. © 2013. The American Astronomical Society. All rights reserved..


Wu X.,Nanchang University | Xie Y.,Nanjing University | Xie Y.,University of Missouri
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2010

The phase space of a Hamiltonian system is symplectic. However, the post-Newtonian Hamiltonian formulation of spinning compact binaries in existing publications does not have this property, when position, momentum, and spin variables [X,P,S1,S2] compose its phase space. This may give a convenient application of perturbation theory to the derivation of the post-Newtonian formulation, but also makes classic theories of a symplectic Hamiltonian system a serious obstacle in application, especially in diagnosing integrability and nonintegrability from a dynamical system theory perspective. To completely understand the dynamical characteristic of the integrability or nonintegrability for the binary system, we construct a set of conjugate spin variables and reexpress the spin Hamiltonian part so as to make the complete Hamiltonian formulation symplectic. As a result, it is directly shown with the least number of independent isolating integrals that a conservative Hamiltonian compact binary system with both one spin and the pure orbital part to any post-Newtonian order is typically integrable and not chaotic. And a conservative binary system consisting of two spins restricted to the leading order spin-orbit interaction and the pure orbital part at all post-Newtonian orders is also integrable, independently on the mass ratio. For all other various spinning cases, the onset of chaos is possible. © 2010 The American Physical Society.


Wang X.,Nanchang University | Wang Z.,Chongqing University
Tetrahedron | Year: 2014

A novel silver-catalyzed tandem reaction of 2-alkynylbenzaldoximes with H-phosphinate esters, and H-phosphine oxides has been developed, providing a general and powerful tool for the synthesis of various 1-phosphorylated isoquinolins in moderate to excellent yield. This reaction proceeded smoothly to construct C-N and C-P bonds in one-pot with good functional group tolerance under mild conditions. © 2014 Elsevier Ltd. All rights reserved.


Deng X.-F.,Nanchang University
Research in Astronomy and Astrophysics | Year: 2013

Using galaxy data from the Sloan Digital Sky Survey Data Release 8, I explore whether the concentration index is a good morphological classification tool and find that a reasonable sample of pure late-type galaxies can be constructed with the choice of the r-band concentration index ci=2.85. The opposite is not true, however, due to the fairly high contamination of an early-type sample by late-type galaxies. In such an analysis, the influence of selection effects is less important. To disentangle correlations of the morphology and concentration index with stellar mass, star formation rate (SFR), specific star formation rate (SSFR) and active galactic nucleus (AGN) activity, I investigate correlations of the concentration index with these properties at a fixed morphology and correlations of the morphology with these properties at a fixed concentration index. It is found that at a fixed morphology, high-concentration galaxies are preferentially more massive and have a lower SFR and SSFR than low-concentration galaxies, whereas at a fixed concentration index, elliptical galaxies are preferentially more massive and have a lower SFR and SSFR than spiral galaxies. This result shows that the stellar mass, SFR and SSFR of a galaxy are correlated with its concentration index as well as its morphology. In addition, I note that AGNs are preferentially found in more concentrated galaxies only in the sample of spiral galaxies. © 2013 National Astronomical Observatories of Chinese Academy of Sciences and IOP Publishing Ltd.


Qin F.,Nanchang University
IEEE Transactions on Fuzzy Systems | Year: 2015

Commuting is an important property in any two-step information merging procedure where the results should not depend on the order in which the single steps are performed. In the case of bisymmetric aggregation operators with the neutral elements, Saminger, Mesiar, and Dubois, have already reduced characterization of commuting n-ary operators to resolving the unary distributive functional equations, but only some sufficient conditions of unary functions distributive over two particular classes of uninorms are given out. Indeed, it is very difficult to get the full characterizations of these equations because they are bound up with the famous Cauchy functional equation, which has so far not been completely solved. Along this way of thinking, in this paper, we will respectively investigate and fully characterize the following two functional equations f(U(x, y)) = S(f(x), f(y)) and f(S(x, y)) = U(f(x), f(y)), where f : [0, 1] ? [0, 1] is an unknown function, U is a representable uninorm, and S is a continuous t-conorm. These results are an important step toward obtaining complete characterization of the other unary distributive functional equations previously mentioned. Our results show that commuting is suitable for only the second equation but not for the first one. This is because solutions of the first equation are all piecewise constant functions, while those of the second equation are formulas with parameters. In addition, the two equations both have nonmonotone solutions completely different from those ones obtained. © 2014 IEEE.


Li G.-P.,Nanchang University
ICCSE 2010 - 5th International Conference on Computer Science and Education, Final Program and Book of Abstracts | Year: 2010

The design and development of an embedded control and data acquisition system is presented. The system is an intelligent remote unit featuring embedded technology for data acquisition, monitoring and output control. Using a high integrated 32-bit RISC microprocessor as well as serial A/D and D/A converters, the electronic systems are compact and the device has high performance. Besides stand-alone, control, supervision or data acquisition tasks can even be accomplished through Ethernet within an industrial Local Area Network (LAN). Compared with the conventional solutions to control and data acquisition, the device based on the embedded system offers the widest range of features and flexibility, with an overall design for reliability, durability and ease of installation. Expanded input and output capabilities can be added to maximate the system's functions. Such an embedded system can be used for diverse applications involved in real-time controls and data acquisitions. Because operation systems can be ported to the hardware, the system can deal with much more complicated tasks that conventional lower computers can't deal with, while the cost is low. ©2010 IEEE.


Wang X.,Harbin Institute of Technology | Ni W.,Nanchang University | Yang J.,McMaster University
IET Control Theory and Applications | Year: 2013

In this study, we consider the distributed output regulation (DOR) problem of linear multi-agent systems subject to input saturation with switching topology. Owing to the input saturation elements, the considered systems is non-linear. It is natural to take the semiglobal frame for it which allows one to use distributed linear feedback controller. The basic problem is to design distributed feedback controller for the considered multi-agent systems in order to have all agents to track an active leader and/or distributed rejection with disturbance signals. Both the leader and the disturbance signal are modelled as the exogenous system with different dynamics and unmeasurable variables. A systematic distributed linear design approach based on the solvability condition is proposed for the considered DOR problem. © The Institution of Engineering and Technology 2013.


Chen Z.,Nanchang University | Zhang X.,Huazhong University of Science and Technology
Communications in Mathematical Physics | Year: 2016

We consider classical as well as weak solutions to the three dimensional Vlasov–Poisson system. Without assuming finiteness of kinetic energy, we prove global existence of classical solutions by assuming the initial datum is smooth enough and has a compact velocity-spatial support, which will be specified in Theorem 1.1. We also establish some propagation results for low moments of weak solutions. © 2016, Springer-Verlag Berlin Heidelberg.


Chen W.,Nanchang University
Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery | Year: 2013

To explore the relationship among the expression of GSK3β, PI3K/Akt signaling transduction pathway,and cytokines IL6 in Chronic Rhinosinusitis. We assayed mRNA and protein for GSK3β, PI3K, Akt by using reverse transcription polymerase chain reaction (RT-PCR) and immunohistochemistry (IHC), and measured the cytokines IL6 mRNA by using reverse transcription polymerase chain reaction (RT-PCR) in the nasal tissue from the patients with Chronic Rhinosinusitis with Nasal Polyps (CRSwNP), Chronic Rhinosinusitis without Nasal Polyps (CRSsNP) and control subjects. The relative expression levels of GSK3β, PI3K, Akt and IL-6 in CRSwNP were 0.6254 ± 0.0584, 0.8239 ± 0.7186, 0.9369 ± 0.0823 and 0.8973 ± 0.0680. But the relative expression levels of GSK3β, PI3K, Akt and IL-6 in control subjects were 0.2684 ± 0.0726, 0.3578 ± 0.0994, 0.6721 ± 0.0590, 0.5898 ± 0.0891. There were significant differences between the groups of CRSwNP and control subjects (t values were 2.358, 3.071, 2.764, and 2.239, respectively, all P < 0.05). There was no significant difference of GSK3β, PI3K, Akt and GSK3β between the groups of CRSwNP and CRSsNP (t values were 1.597, 1.842, 1.468 and 0.926, respectively, all P < 0.05). GSK3β, PI3K, Akt were not only expressed in the cytoplasm of the epithelium and gland cells, but also in the cytoplasm of the inflammatory cell. GSK3β, PI3K, Akt protein in CRS were detected at a higher rate than the normal nasal tissue (values were 16.42, 16.25 and 15.57,respectively, all P < 0.01). However there was no significant difference of GSK3β, PI3K, Akt protein between the groups of CRSwNP and CRSsNP (values were 3.27, 2.85 and 2.46, respectively, all P > 0.05). There was a positive correlation trend among the expression of GSK3β, PI3K and Akt, and IL-6 in CRS (r values were 0.645, 0.617 and 0.583,respectively, all P < 0.01). The abnormal expression of IL-6, PI3K, Akt and GSK3β in the nasal mucosa of CRS may play a pro-inflammatory role in the occurrence and development of CRS.


Tang L.,Nanchang University
Faguang Xuebao/Chinese Journal of Luminescence | Year: 2015

YVO4:Tm3+ nanophosphors were synthesized by solvothermal method. X-ray diffraction (XRD), transmission electron microscope (TEM), ultraviolet analyzer, ultraviolet-visible (UV-Vis) absorption spectra, and photoluminescence (PL) spectra were used to characterize and analyze the nanophosphors. The experiment results show that YVO4:Tm3+ nanophosphors have bright blue light emission with high color purity and luminescence intensity, and have good thermal stability properties. Therefore, YVO4:Tm3+ nanophosphors are very suitable phosphors for field emission display. ©, 2015, Chines Academy of Sciences. All right reserved.


Yinghui P.,Xiamen University | Yinghui P.,Nanchang University
Journal of Convergence Information Technology | Year: 2010

Watermark perceptibility and robustness must be ensured in order to enhance the practicality of digital watermarking. Taking human visual system characteristics into account fully, a particle swarm optimization method based on multi-wavelet digital watermarking is proposed. It utilizes Sa4 multi-wavelet to embed digital watermark, chooses intermediate frequency in embedding digital watermark adaptively according to the size of every energy mass, and uses multi-objective optimization method based on particle swarm optimization to optimize and adjust the embedded depth to obtain optimal effect. Experiments show the new proposed algorithm not only ensures the quality of watermarking-embed image and robustness against attacks, but also accelerate the operating speed relative to genetic algorithms.


Wu R.,Nanchang University
Rheumatology International | Year: 2014

To investigate role of eye's sign in the patients with neuropsychiatric systemic lupus erythematosus (NPSLE). The scores of eye's sign in bulbar conjunctival microvascular changes were assessed in all patients according to our criteria. The disease activity was measured with SLE Disease Activity Index (SLEDAI) score. Anticardiolipin antibody (aCL) and hemorheology were performed in patients. The eye's sign and whole-blood viscosity were significantly higher in NPSLE patients than those in non-NPSLE patients. The eye's sign has a correlation with SLEDAI, disease duration, whole-blood viscosity, serum concentration of aCL, and no correlation with erythrocyte sedimentation rate, complement and titre of ANA (Anti-nuclear antibody). Our results suggest that eye's sign plays an important role in active NPSLE. The continuous disease activity promotes the vascular damage through an increasing blood viscosity and the eye's sign reflects well this condition. Checking the eye's sign is an useful indicator in assessment of activity or that of effectiveness in treating (NP)SLE. © 2013 Springer-Verlag.


Xiong Y.-H.,Hubei University | Xiong Y.-H.,Peoples Hospital of Gansu Province | He L.,Hubei University | Fei J.,Nanchang University
International Immunopharmacology | Year: 2014

Cytotoxic T-lymphocyte antigen-4 (CTLA-4), a molecule expressed predominantly on activated T cells, plays an important role in the down-regulation of T-cell activation. To evaluate the potential effects of CTLA-4 gene polymorphisms on susceptibility to cervical cancer, we genotyped polymorphisms in CTLA-4 (- 318 T/C, CT60 G/A, + 49 G/A, - 658 T/C, and - 1661 G/A) and calculated odds ratios for the genotype and allele distributions between patients and controls. We then examined the functional relevance of the polymorphisms using enzyme-linked immunosorbent assays (ELISAs), in vitro lymphocyte proliferation assay, and cytotoxic assay. The CTLA-4 - 318 CC, CT60 AA, and + 49 GG genotype frequencies were lower in patients than in controls (p < 0.05). The frequencies of CTLA-4 - 318 T allele and CT60G allele carriers were significantly higher in patients than in controls (p < 0.05). Upon stimulation, peripheral blood mononuclear cells (PBMCs) carrying the - 318TT and CT60GG genotypes exhibited significantly lower proliferation, IL-2, and IL-4 levels; fewer cytolytic activities; and higher TGF-β levels compared with PBMCs carrying the - 318 CC/CT or CT60 AA/AG genotypes. We also found that CTLA-4 - 318 T/C and CT60 G/A single nucleotide polymorphisms were associated with the severity of cervical cancer. These results indicate that CTLA-4 - 318 T/C and CT60 G/A can affect cervical cancer susceptibility by altering the immune status of an individual. © 2013 Elsevier B.V. All rights reserved.


Zhang R.,Nanchang University
International Journal of Advanced Robotic Systems | Year: 2013

A decomposition-based optimization algorithm is proposed for solving large job shop scheduling problems with the objective of minimizing the maximum lateness. First, we use the constraint propagation theory to derive the orientation of a portion of disjunctive arcs. Then we use a simulated annealing algorithm to find a decomposition policy which satisfies the maximum number of oriented disjunctive arcs. Subsequently, each subproblem (corresponding to a subset of operations as determined by the decomposition policy) is successively solved with a simulated annealing algorithm, which leads to a feasible solution to the original job shop scheduling problem. Computational experiments are carried out for adapted benchmark problems, and the results show the proposed algorithm is effective and efficient in terms of solution quality and time performance. © 2012 Licensee InTech.


Lu L.,Nanchang University
Jixie Gongcheng Xuebao/Journal of Mechanical Engineering | Year: 2013

Vibration physical model of a new type of bearing is established on the basis of depth study for its structure and working mechanism. The mathematical model is established by vibration mechanics theory. The characteristic equation and characteristic solution of the inherent vibration is obtained by the mathematical model. The adjunctive matrix is obtained by the system's inherent vibration equation. The dominant mode of vibration is obtained by the adjunctive matrix. The main mass matrix is obtained by the dominant mode of vibration. The regular modal matrix is obtained by the main mass matrix. The steady-state response expression of the new bearing is obtained. The vibration modes and amplitude of the system are analyzed by steady-state response expression. And some of the factors that affect the system amplitude are analyzed by calculation and experiment. The results show that the system exist the two main modes that are the same vibration in positive or negative of x and y directions and the opposite direction vibration in positive or negative of x and y directions, and the factors that make the new bearing resonance are inner quality and number of roller and inner rotary position and the stiffness of roller and the stiffness of the oil wedge between that exist between the slider and the rings, and the system will resonance when the factors combine in a certain way and its value is equal to the excitation frequency, and the vibration amplitude of the new bearing is unchanged during the rotation of the inner ring and is inversely proportional to the number of the roller and the roller radial direction stiffness. © 2013 Journal of Mechanical Engineering.


Zhang R.,Nanchang University | Wu C.,Tsinghua University
Information Sciences | Year: 2012

Practical production scheduling problems usually involve some "bottleneck" machines, the scheduling policies for which could significantly affect the final solution quality. Therefore, it is beneficial to identify the bottleneck machines beforehand, so that we can intensify the optimization for these machines in the subsequent solving stage. To this end, a bottleneck machine identification algorithm is proposed in this paper for the job shop scheduling problem with the objective of minimizing total tardiness. In order to obtain the instance-specific information about bottleneck machine distribution, we first propose a new optimization model which relaxes some conventional constraints of the standard job shop problem. Then, a simulated annealing algorithm is applied to solve this newly defined problem. Based on the optimization result, the bottleneck characteristic value (which is a measure of bottleneck level) is calculated for each machine. To utilize the obtained bottleneck information for job shop scheduling, we design a genetic algorithm which allocates more computational resources to the identified bottleneck machines by using a hybrid encoding scheme. Computational results verify the effectiveness and the robustness of the proposed bottleneck identification procedure. It is shown that intensifying the local search effort for the bottleneck machines will generally result in higher solution quality within reasonably short computational time. © 2011 Elsevier Inc. All rights reserved.


Peng F.-K.,Nanjing University | Tang Q.-W.,Nanchang University | Wang X.-Y.,Nanjing University
Astrophysical Journal | Year: 2016

Massive black holes at galaxy center may tear apart a star when the star passes occasionally within the disruption radius, which is the so-called tidal disruption event (TDE). Most TDEs radiate with thermal emission resulting from the acceleration disk, but three TDEs have been detected in bright nonthermal X-ray emission, which is interpreted as arising from the relativistic jets. A search for high-energy gamma-ray emission from one relativistic TDE (Swift J164449.3+573451) with the Fermi Large Area Telescope (LAT) has yielded nondetection. In this paper, we report the search for high-energy emission from the other two relativistic TDEs (Swift J2058.4+0516 and Swift J1112.2-8238) during the flare period. No significant GeV emission is found, with an upper limit fluence in the LAT energy range being less than 1% of that in X-rays. Compared with gamma-ray bursts and blazars, these TDEs have the lowest flux ratio between GeV emission and X-ray emission. The nondetection of high-energy emission from relativistic TDEs could be due to the fact that the high-energy emission is absorbed by soft photons in the source. Based on this hypothesis, upper limits on the bulk Lorentz factors, Ω ≲ 30, are then obtained for the jets in these TDEs. We also search for high-energy gamma-ray emission from the nearest TDE discovered to date, ASASSN-14li. No significant GeV emission is found, and an upper limit of erg s-1 (at 95% confidence level) is obtained for the first 107 s after the disruption. © 2016. The American Astronomical Society. All rights reserved.


Zeng X.-H.,Nanchang University | Navarro B.,Howard Hughes Medical Institute | Xia X.-M.,Washington University in St. Louis | Clapham D.E.,Howard Hughes Medical Institute | And 2 more authors.
Journal of General Physiology | Year: 2013

During passage through the female reproductive tract, mammalian sperm undergo a maturation process termed capacitation that renders sperm competent to produce fertilization. Capacitation involves a sequence of changes in biochemical and electrical properties, the onset of a hyperactivated swimming behavior, and development of theability to undergo successful fusion and penetration with an egg. In mouse sperm, the development of hyperactivated motility is dependent on cytosolic alkalization that then results in an increase in cytosolic Ca2+.The elevation of Ca2+ is thought to be primarily driven by the concerted interplay of two alkalization-activated currents, a K+ current (KSPER) composed of pore-forming subunits encoded by the Kcnu1gene (also termed Slo3) and a Ca2+ current arising from a family of CATSPER subunits. After deletion of any of four CATSPER subunit genes (CATSPER1-4), the major remaining current in mouse sperm is alkalization-activated KSPER current. After genetic deletion of the Slo3 gene, KSPER current is abolished, but there remains a small voltage-activated K+current hypothesized to reflect monovalent flux through CATSPER. Here, we address two questions. First, does the residual outward K+current present in the Slo3-/-sperm arise from CATSPER? Second, can any additional membrane K+currents be detected in mouse sperm by patch-clamp methods other than CATSPER and KSPER? Here, using mice bred to lack both SLO3 and CATSPER1 subunits,we show conclusively that the voltage-activated outward current present in Slo3-/- sperm is abolished when CATSPER is also deleted. Any leak currents that may play a role in setting the resting membrane potentialinnoncapacitated sperm are likely smaller than the pipette leak current and thus cannot be resolved within the limitation of the patch-clamp technique. Together, KSPER and CATSPER appear to be the sole ion channels present in mouse sperm that regulate membrane potential and Ca2+ influx in response to alkalization. © 2013 Zeng et al.


Yang S.-T.,Fudan University | Shi Y.,Fudan University | Wang Q.,Fudan University | Peng J.-Y.,Fudan University | And 2 more authors.
Molecular Brain | Year: 2014

Working memory is a process for short-term active maintenance of information. Behavioral neurophysiological studies in monkeys have demonstrated that the dorsolateral prefrontal cortex (dlPFC) is a key cortical region for working memory. The medial prefrontal cortex (mPFC) in rats is a cortical area similar to the dlPFC in monkeys in terms of anatomical connections, and is also required for behavioral performance on working-memory tasks. However, it is still controversial regarding whether and how mPFC neurons encode working memory. In the present study, we trained rats on a two-choice spatial delayed alternation task in Y maze, a typical working memory task for rodents, and investigated neuronal activities in the mPFC when rats performed the task. Our results show that, (1) inactivation of the mPFC severely impaired the performance of rats on the task, consistent with previous studies showing the importance of the mPFC for working-memory tasks; (2) 93.7% mPFC cells (449 in 479) exhibited changes in spiking frequency that were temporally locked with the task events, some of which, including delay-related cells, were tuned by spatial information; (3) differential delay activities in individual mPFC cells appeared transiently and sequentially along the delay, especially during the early phase of the delay; (4) some mPFC cells showed no change in discharge frequency but exhibited differential synchronization in firing during the delay. The present results suggest that mPFC neurons in rats are involved in encoding working memory, via increasing firing frequency or synchronization. © 2014 Yang et al.; licensee BioMed Central Ltd.


Wu J.J.,Chung Hua University | Hou D.J.,National Taiwan Normal University | Liu K.,Zhejiang University | Shen L.,Nanchang University | And 4 more authors.
Optics Express | Year: 2014

We apply the concept of spoof surface plasmon polaritons (SPPs) to the design of differential microstrip lines by introducing periodic subwavelength corrugations on their edges. The dispersion relation and field distribution of those lines are analyzed numerically. And then through designing practical coupling circuits, we found that compared with conventional differential microstrip lines, the electromagnetic field can be strongly confined inside the grooves of the corrugated microstrip lines, sothe crosstalk between the differential pair and the adjacent microstrip lines is greatly reduced, and the conversion from the differential signal to the common mode signal can also be effectively suppressed. The propagation length of those lines is also very long in a wide band. Moreover, the experimental results in time domain demonstrate those lines perform very well in high-speed circuit. Therefore, those novel kinds of spoof SPPs based differential microstrip lines can be widely utilized in high-density microwave circuits and guarantee signal integrity in high-speed systems. © 2014 Optical Society of America


Feng W.,Nanchang University
Advanced Materials Research | Year: 2014

Many empirical formulas and diagrams have been employed to determine resistance coefficient of elbow/bend pipes. However, a big discrepancy of calculation results obtained from these formulas/diagrams exists. So it is difficult for users to choose an appropriate formula to calculate resistance coefficient of an elbow/bend pipe. In this paper, a comparison of several common formulas was made. And variations of resistance coefficient with both bend angle and curvature radius were graphically shown for reference of selection. In addition, flow characteristics in elbow pipe were analyzed. © (2014) Trans Tech Publications, Switzerland.


Peng D.,Nanchang University | Zhang X.,Nanjing Southeast University
Energy | Year: 2011

Solar liquid collector/regenerator combines solar photothermic transformation and liquid regeneration together for solar energy-driven liquid desiccant cooling systems. A group of dimensionless heat and mass transfer equations describing the heat and mass transfer process in the solar C/R(Collector/Regenerator) were obtained by introducing total temperature difference (ΔT0) and dimensionless heat loss coefficient (hz). The increment of solution concentration ΔC was increased 2.9-3.5%/°C and 5.3%/°C for increasing unit inlet temperature of air stream and solution respectively and increased about 6.2%/(g/kg) and 0.9%/(g/kg) for decreasing unit inlet humidity ratio of air and solution concentration. Besides, the increasing number of heat transfer units (NTU), air-to-salt mass flow rate ratio (ASMR) and total temperature difference (ΔT0) can increase the performance of solution regeneration significantly. Compared to parallel flow regeneration, the performance of counterflow regeneration was increased about 10%. © 2011 Elsevier Ltd.


Peng D.,Nanchang University | Zhang X.,Nanjing Southeast University
Applied Energy | Year: 2011

Solar collector/regenerator (C/R) using liquid desiccant combines solar photothermic transformation and regeneration of liquid desiccant together, effectively achieving the regeneration for solar energy-driven liquid desiccant cooling systems. In this paper a group of dimensionless heat and mass transfer equations describing the heat and mass transfer process in the solar C/R were obtained by introducing total temperature difference (ΔT0) and dimensionless heat loss coefficient (hz). For the sake of predicting the heat loss of air stream and simplifying calculation, the models of dimensionless air temperature (θa) and equilibrium humidity ratio (YeL) along with the height of solar C/R were put forward. An analytical solution was formed by two differential equations on the dimensionless heat and mass transfer driving potentials and the heat and mass conservation equations. Compared with the numerical simulation results, the analytical results on the outlet parameters of solar C/R have great precision with different Lewis factor Le, total temperature difference ΔT0 and air-to salt mass flow rate ratio ASMR. Simultaneously, the effects of above variables on the regeneration performance were analyzed. Lastly, by comparing with the experimental data, the analytical calculation results can agree well with the experimental results validating the analytical model is an ideal way for predicting the performance of the solar C/R. © 2011 Elsevier Ltd.


Luo R.-Z.,Nanchang University | He L.-M.,Shanghai University
Chinese Physics B | Year: 2014

The PC synchronization of a class of chaotic systems is investigated in this paper. The drive system is assumed to have only one state variable available. By constructing proper observers, some novel criteria for PC synchronization are proposed via event-triggered control scheme. The Lü system and Chen system are taken as examples to demonstrate the efficiency of the proposed approach. © 2014 Chinese Physical Society and IOP Publishing Ltd.


Zhao B.,Tsinghua University | Wang Q.,Tsinghua University | Wang Q.,CAS Institute of Zoology | Du J.,Tsinghua University | And 3 more authors.
Cell Research | Year: 2012

Protein that interacts with C kinase 1 (PICK1) is a critical mediator of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) trafficking in neural synapses. However, its ubiquitous expression suggests that it may have other non-neural functions. Here we show that PICK1 antagonizes transforming growth factor beta (TGF-β) signaling by targeting TGF-β type I receptor (TβRI) for degradation. Biochemical analyses reveal that PICK1 directly interacts with the C-terminus of TβRI via its PDZ domain and acts as a scaffold protein to enhance the interaction between TβRI and caveolin-1, leading to enhanced lipid raft/caveolae localization. Therefore, PICK1 increases caveolin-mediated endocytosis, ubiquitination and degradation of TβRI. Moreover, a negative correlation between PICK1 expression and TβRI or phospho-Smad2 levels is observed in human breast tumors, indicating that PICK1 may participate in breast cancer development through inhibition of TGF-β signaling. Our findings reveal a non-neural function of PICK1 as an important negative regulator of TGF-β signaling. © 2012 IBCB, SIBS, CAS All rights reserved.


Chen H.,Nanchang University
Optimal Control Applications and Methods | Year: 2013

This paper mainly studies the problem of the robustly stability analysis for uncertain neutral system with mixed time-varying delays. By constructing an augmented Lyapunov-Krasovskii functional, some new delay-dependent criteria can be established in terms of linear matrix inequalities. Compared with some existing results, our delay-dependent criteria can be shown to be some less conservative ones via some illustrative numerical examples. Copyright © 2012 John Wiley & Sons, Ltd. Copyright © 2012 John Wiley & Sons, Ltd.


Qiu K.,Nanchang University
Advanced Materials Research | Year: 2014

Nowadays the simplification, similarity and transition presented in the wine packaging design ideas cause multifarious and disordered bottle packaging forms and resources waste of wine packaging products and so on. Based on these problems, this essay attempts to introduce TRIZ innovative design in wine packaging design. Analysis wine packaging in hand, categorizes and summarizing common problems existing in all sorts of wine packaging designs, based on the idealized principle of TRIZ propose ideal solution to wine packaging, clear basic targets of wine packaging design. Finally using 40 innovative principles of TRIZ explore a reasonable, normative and innovative design for wine packing, lay a theoretical basis for the development to greening, individuation, brand and localization, and internationalization. © (2014) Trans Tech Publications, Switzerland.


Zhang R.,Nanchang University
Journal of Convergence Information Technology | Year: 2011

Job shop scheduling is a crucial decisional process in contemporary manufacturing systems characterized by product diversity. The problem is strongly NP-hard in terms of computational complexity. Therefore, both exact and meta-heuristic algorithms have inherent drawbacks when faced with large-scale job shops. In this paper, we propose a hybrid optimization algorithm which integrates constraint propagation with simulated annealing. A probabilistic mechanism is introduced into the constraint propagation module in order to promote the overall optimization efficiency. Finally, the computational experiments on a selected set of benchmark instances show that the proposed approach is effective for solving the job shop scheduling problem.


Zhang R.,Nanchang University
International Journal of Advancements in Computing Technology | Year: 2011

Job shop scheduling is a significant decision problem in complex manufacturing processes. Most existing research has been focused on the standard job shop model where each job is composed of a set of operations connected by chain-type precedence relations. However, in real-world workshops, many jobs require the assembly operations which may have more than one predecessor operations. So in this paper, we propose a genetic algorithm with a rule-based encoding scheme and a simulation-based solution evaluation method for solving the job shop scheduling problem involving assembly operations. The objective function is an aggregation of the makespan and the on-time delivery rate. The computational experiments on a set of randomly generated test instances show that the proposed algorithm is effective.


Zhang R.,Nanchang University
International Journal of Digital Content Technology and its Applications | Year: 2011

Job shop scheduling is a significant optimization problem in contemporary manufacturing systems characterized by product customization. In the early years, exact solution methods (such as branchand- bound) dominated the algorithm research for solving the job shop scheduling problem. However, due to the growing scale of the problem instances that we face nowadays, the recent research has been focused on meta-heuristic algorithms almost exclusively. In fact, both exact and meta-heuristic algorithms have systematic drawbacks when faced with complex job shops. It will be advantageous if the two extreme approaches could be combined and compromised. Based on such an idea, we propose a hybrid heuristic algorithm integrating constraint propagation (which tends to be an exact methodology) with simulated annealing (which is a renowned meta-heuristic). Finally, the computational experiments on a set of benchmark instances show that the proposed heuristic is effective and efficient for solving the job shop scheduling problem with makespan criterion.


Jiang Y.,Nanchang University | Jiang D.,Wuhan University
International Journal of Digital Content Technology and its Applications | Year: 2011

In this paper, we investigate the multiple attribute decision making (MADM) problems for for evaluating the security of wireless sensor network (WSN) with interval grey linguistic variables. We utilize the interval grey linguistic weighted geometric (IGLWG) operator to aggregate the interval grey linguistic variables corresponding to each alternative and get the overall value of the alternatives, then rank the alternatives and select the most desirable one(s). Finally, an illustrative example is given.


Zhu Y.,Nanchang University
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi | Year: 2011

The present investigation was to construct lentiviral vector carrying the human gene NK4 and transfect the human bone mesenchymal stem cells (hBMSCs) and to determine the expression of NK4 gene in hBMSCs after transfection. The NK4 gene was obtained from HGF cDNA by polymerase chain reaction(PCR), and the pGC-FU-NK4 plasmid was constructed by double restriction enzyme digestion and gene recombinant. The titer of virus was tested by real-time quantitative PCR. After transfected by lentivirus, the green fluorescent protein (GFP) in hBMSCs was observed using fluorescence microscope, and the expression of NK4 in culture supernatant was detected by enzymelinked immunosorbent assay (ELISA). The sequence of the PCR product was consistent with the data of GeneBank by DNA sequencing. The virus titer was 2 X 10(8)TU/ml. Strong green fluorescence was observed in the cell membrane and cytoplasm of hBMSCs with fluorescent microscopy. The expression of NK4 in culture supernatant was increased with time extension. The hBMSCs can be transfected by NK4 gene expressing lentiviral vector safely and effectively, and the expressin and secretion of NK4 was persistent and stable.


From theMain galaxy sample of the Sloan Digital Sky Survey Data Release 7, I construct two volume-limited samples with luminosities -20.5 ≤ M r ≤ -18.5 and -22.5≤ Mr ≤-20.5, respectively, to explore the environmental dependence of the star formation rate (SFR) and the specific star formation rate (SSFR) at fixed morphology. It is found that in these two volume-limited samples, galaxies in the lowest density regime preferentially have higher SFR and SSFR than galaxies in the densest regime. I divide each volume-limited Main galaxy sample into two distinct populations, the early type and the late type, and observe that the environmental dependence of the SFR and SSFR of galaxies remains true at fixed morphology: the SFR and SSFR of galaxies in the densest regime is still preferentially lower than that of the ones in the lowest density regime with the same morphological type. I also note that the environmental dependence of the SFR and SSFR of late-type galaxies is stronger than that of early-type galaxies. © 2010. The American Astronomical Society. All rights reserved.


Xiao S.-B.,Nanchang University
Applied Mechanics and Materials | Year: 2014

In the paper the interactive multimedia network autonomous learning platform is analyzed, through which its use case diagram is presented. The autonomous learning platform consists of user register module, user login module, teacher profile module, discussion and Q/A module, online test module, learning video module, system introduction module, material download module and backstage administration module. Primarily, the design and development of the platform is meant to solve the problem of data exchange between database and pages. Data are updated or deleted when the data of pages are transmitted to backstage database. The implementation of the autonomous learning platform fulfills people's urgent demands of the online education, settles the drawback that education and being educated in traditional approach cannot be conducted at different time and in different places, and enhances the efficiency of teacher's teaching and students' learning enormously as well. © (2014) Trans Tech Publications, Switzerland.


Hui X.,Nanchang University
Applied Mechanics and Materials | Year: 2014

Through in-depth research on branding and marketing microblogging theory, summarizes the advantages and methods based automotive marketing microblogging branding strategy, analyze the current situation of the car microblogging marketing, implementation and effectiveness of the monitoring of the development of automobile brand communication strategy will be comprehensive exposition, based on theoretical build car branding and marketing strategy microblogging system. © (2014) Trans Tech Publications, Switzerland.


Xie X.,Baylor College of Medicine | Tang K.,Baylor College of Medicine | Tang K.,Nanchang University | Yu C.-T.,Baylor College of Medicine | And 2 more authors.
Seminars in Cell and Developmental Biology | Year: 2013

The formation of complex organisms is highly dependent on the differentiation of specialized mature cells from common stem/progenitor cells. The orphan nuclear receptors chicken ovalbumin upstream promoter transcription factors (COUP-TFs) are broadly, but not ubiquitously, expressed in multiple tissues throughout embryonic development and COUP-TFs are indispensible for proper organogenesis. Recently, growing evidence suggests a critical role of COUP-TFs in multiple aspects of stem/progenitor cell biology. In this review, we highlight the progress of COUP-TFs function and its underlying mechanism in driving stem/progenitor cell self-renewal, lineage specification, differentiation, maintenance, and cell identity in diverse tissue types. These studies provide novel insights into future clinical utilities of COUP-TFs in stem cell based therapies and in the management of diseases. © 2013 Elsevier Ltd.


Chen F.-S.,Jiangxi Agricultural University | Yavitt J.,Cornell University | Hu X.-F.,Nanchang University
Applied Soil Ecology | Year: 2014

We used four vegetation types located along an urban-suburban-rural gradient in Nanchang, China to study how the deposition of nitrogen (N) and phosphorus (P) in the urban area affected soil carbon (C) cycling. We found that total P, nitrate (NO3 --N), available P, and the abundances of culturable bacteria, actinobacteria, and nitrifying bacteria in soils, collected to 15cm depth in August of 2008, decreased along the urban-to-rural gradient (P<0.05); the C/P and N/P ratios, ammonium (NH4 +-N), and culturable fungi abundance showed the reverse trends; whereas soil organic C, total N, C/N, mineral N, and the activities of sucrase and neutraland acid phosphatase showed no pattern with gradient and vegetation type. Compared to suburban and rural sites, total and available P in soil increased 168% and 131%, 47% and 139%, respectively in urban sites. The cumulative amount of CO2 emission per gram of soil (Cmin, incubated from 2 to 43 days) varied little along the urban-to-rural gradient, but showed positive correlations with organic C, total N, total P, nitrate, mineral N concentrations, C/N, bacteria and actinobacteria abundances, sucrase and acid phosphatase activities. In contrast, the cumulative amount of CO2 produced per gram organic C (Cmin/OC) within the incubation period was influenced by gradient, vegetation type, and their interaction, and values were about 35% greater in the urban than in suburban and rural sites. The relationship between elevated Cmin/OC in urban vegetations and the enrichment of P in organic matter (P/C ratio) suggests that P coming from urban household waste can degrade the stability of organic C in urban soils. © 2013 Elsevier B.V.


Wang Z.,Nanchang University
International Journal of Simulation: Systems, Science and Technology | Year: 2015

The track level measurement based on multi-sensor information fusion is studied. The Kalman filter and weighted fusion estimation algorithm is used to fuse the angle sensor and the measurement data of MEMS gyroscope. It can be seen that the experimental data of the weighted fusion is more close to the real value of the MEMS gyroscope, and the random drift of MEMS gyroscope is reduced to a certain extent. © 2015, UK Simulation Society. All rights reserved.


Wang L.-W.,Nanchang University | Han X.-M.,Huazhong University of Science and Technology | Chen C.-H.,Huazhong University of Science and Technology | Ma Y.,Huazhong University of Science and Technology | Hai B.,Huazhong University of Science and Technology
International Urology and Nephrology | Year: 2014

Purpose: To investigate the diagnostic performance of urinary brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) as potential biomarkers for overactive bladder (OAB). Methods: Ninety women diagnosed with OAB and 45 normal controls without OAB were enrolled. Urine samples were collected from all subjects. Urinary BDNF and NGF levels were measured using enzyme-linked immunosorbent assays. Results normalized by urinary creatinine (Cr) levels were compared between OAB groups and controls. Symptom severity was assessed using overactive bladder symptom score. Results: Urinary BDNF and NGF levels were elevated in OAB groups but not in controls. Mean (SD) baseline BDNF and NGF levels normalized by Cr levels were significantly higher in OAB subjects than in controls (20.609 ± 23.932 vs. 1.779 ± 0.729, p < 0.01) and (0.258 ± 0.264 vs. 0.081 ± 0.028, p < 0.01), respectively. Urinary BDNF/Cr levels were 80-fold higher than NGF/Cr levels in OAB subjects. Receiver operating characteristic curves for assessing urinary BDNF/Cr levels in OAB groups showed sensitivity and specificity of 93.33 and 88.89 %, respectively. Urinary BDNF levels were associated with OAB symptom severity. Conclusions: Urinary BDNF/Cr levels are elevated in women with OAB and are significantly associated with symptom severity. No elevation of BDNF is found in women without OAB. BDNF analysis has better sensitivity than NGF in detecting OAB in subjects without other lower urinary tract disorders. Results of the present study suggest a potential role for BDNF as an objective biomarker for OAB diagnosis. © 2013 Springer Science+Business Media.


Liu G.-L.,Southern Medical University | Yang H.-J.,Nanchang University | Liu T.,Southern Medical University | Lin Y.-Z.,Wenzhou University
Asian Pacific Journal of Tropical Medicine | Year: 2014

Objective: To study the expression of E-cadherin, N-cadherin, TGF-β1 and Twist protein and investigate its significance in the occurrence and development of prostate cancer. Methods: The expression of E-cadherin, N-cadherin, TGF-β1 and Twist protein in 59 prostate cancer tissues and 21 adjacent tissues were detected by immunohistochemical SABC staining, and the correlation with clinicopathological features was analyzed. Results: Positive rates of E-cadherin, N-cadherin, TGF-β1 and Twist were 32.2%, 54.2%, 71.2% and 74.6%, respectively, in prostate cancer tissues and 85.7%, 9.52%, 19.0% and 9.52%, respectively, in cancer-adjacent tissues, with significant differences between the two groups (P<0.05). The reduced expression of E-cadherin was related to the differentiation of prostate cancer tissues and PSA level, but was not associated with clinical stage, lymph node metastasis, bony metastasis and age. The increased expression of N-cadherin, TGF-β1 and Twist was related to the differentiation of prostate cancer tissues, clinical stage, lymph node metastasis, bony metastasis, but not to age. The difference in positive expression of N-cadherin and TGF-β1 was significant between PSA≤20 μg/L group and PSA>20μg/L group, but the positive expression of Twist was not significant between groups. The expression of E-cadherin was highly negatively correlated with that of N-cadherin and also highly negatively correlated with that of Twist. The expression of TGF-β1 was correlated with those of E-cadherin, N-cadherin and Twist. Conclusions: The reduced expression of E-cadherin, abnormal expression of N-cadherin, transformation form E-cadherin to N-cadherin and the increased expression of TGF-β1 and Twist play an important role in the occurrence and development of prostate cancer. © 2014 Hainan Medical College.


Chen J.,Nanchang University | Chen J.,Zhejiang University | Zhu L.,Zhejiang University
Journal of Hazardous Materials | Year: 2011

An enhanced method of hydroxyl-Fe-pillared bentonite (H-Fe-P-B) during the degradation of Orange II was studied to provide novel insight to interactions of degradation intermediates with heterogeneous catalyst in UV-Fenton system. Based on the degradation mechanism of Orange II, oxalate enhanced mechanism of H-Fe-P-B in heterogeneous UV-Fenton system was developed. The results showed that additional oxalate could increase the Fe leaching of H-Fe-P-B during heterogeneous UV-Fenton process, which led to higher mineralization efficiency of Orange II and lower energy consumption of treatment. When the concentrations of additional sodium oxalate increased up to 0.1mmolL-1, 0.2mmolL-1 and 0.4mmolL-1, the rate of Orange II degradation could increase 30%, 46% and 63%, respectively. The iron ions leached from catalyst could be adsorbed back to the catalyst again after the organic intermediates were mineralized completely. Then the catalyst of H-Fe-P-B could be reused and additional pollution caused by iron ions could be avoided. © 2010 Elsevier B.V.


Deng X.-F.,Nanchang University
Astronomische Nachrichten | Year: 2015

In this study, I attempt to apply for a new statistical method and investigate the environmental dependence of stellar mass and stellar velocity dispersion in the CMASS sample of the Sloan Digital Sky Survey Data Release 9 (SDSS DR9). I divide the CMASS sample with redshifts 0.44 ≤ z ≤ 0.59 into many subsamples with a redshift binning size of Δz = 0.01, and analyze the environmental dependence of stellar mass and stellar velocity dispersion of subsamples in each redshift bin. It is found that stellar mass and stellar velocity dispersions of CMASS galaxies are very weakly correlated with the local environment. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Cheng X.Y.,Nanchang University
Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology | Year: 2010

To explore the roles of CD14 and TLR4 in severe hepatitis B induced by endotoxin. The levels of mCD14 on PBMCs from 30 cases of severe hepatitis B, 20 cases of chronic hepatitis B and 20 cases of healthy controls were detected by flow cytometry. The expressions of CD14 mRNA and TLR4 mRNA in PBMCs from these patients were also detected by RT-PCR. Meanwhile, the concentration of plasma endotoxin was detected by limulus amebocyte lysate test and the levels of TNF alpha, IL-1, IL-6 in serum were detected by ELISA. The levels of mCD14 on PBMCs in severe hepatitis B, chronic hepatitis B and control were 74.2+/-12.3, 63.6+/-11.8 and 60.3+/-7.2 respectively. There was a significant difference among severe hepatitis B,chronic hepatitis B and healthy controls (both of P less than 0.01). The expressions of CD14 mRNA and TLR4 mRNA (2.92+/-0.67 and 1.86+/-0.45) were also upregulated, compared with that in chronic hepatitis B patients (1.34+/-0.51, 0.93+/-0.18) and healthy group (0.92+/-0.58, 0.73+/-0.16) (P less than 0.01). Similarly, the concentration of plasma endotoxin was much higher in severe hepatitis B (1.87+/-1.61) than that in chronic hepatitis B patients (0.11+/-0.11) and that in healthy group (0.03+/-0.03) (P less than 0.01). As a result, the inflammation cytokines, such as TNF alpha, IL-1 and IL-6 (19.78+/-9.21, 0.96+/-0.16, 68.34+/-48.30) also increased significantly in severe hepatitis B, which were remarkably higher than those in chronic hepatitis B patients (7.26+/-6.52, 0.19+/-0.02 and 19.28+/-4.65) and healthy group (4.15+/-4.06, 0.15+/-0.01 and 12.01+/-3.88) (P less than 0.01). Furthermore, correlation analysis showed there was positive correlation among the level of mCD14, the expression of CD14 mRNA/TLR4 mRNA, the concentration of endotoxin and the levels of inflammation cytokines in severe hepatitis B (r1 = 0.865, r2 = 0.415, r3 = 0.524, all of P less than 0.05). Endotoxin is an important factor in the aggravation of hepatitis B. Meanwhile, mCD14, CD14 mRNA and TLR4 mRNA are remarkably upregulated during the endotoxin stimulation. The inflammation cytokines (TNF alpha, IL-1 and IL-6) are also elevated, which may finally result in the aggravation of the hepatitis B. Therefore, CD14, TLR4 and inflammation cytokines play important roles in pathogenesis of severe hepatitis B induced by endotoxin.


He D.,Nanchang University
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery | Year: 2012

To summarize the recent development on chondroprotective effect of alendronate (ALN) on articular cartilage in osteoarthritis (OA). The related literature was reviewed and the main achievements in vitro/vivo studies in the fields were summarized. ALN can improve the metabolic microenvironment of the articular cartilage in OA, inhibit subchondral bone remodeling, so it has potential protective effect on articular cartilage. ALN is expected to become a disease-modifying OA drug in future, but OA treatment still lack a uniform basic and clinical evaluation criteria, so it has guiding significance in development and application of ALN to develope a uniform standard and obtain the clinical data.


Yang J.,Tsinghua University | Liu Z.,Tsinghua University | Grey F.,Tsinghua University | Xu Z.,Tsinghua University | And 6 more authors.
Physical Review Letters | Year: 2013

A sheared microscopic graphite mesa retracts spontaneously to minimize interfacial energy. Using an optical knife-edge technique, we report first measurements of the speeds of such self-retracting motion (SRM) from the mm/s range at room temperature to 25 m/s at 235 C. This remarkably high speed is comparable with the upper theoretical limit found for sliding interfaces exhibiting structural superlubricity. We observe a strong temperature dependence of SRM speed which is consistent with a thermally activated mechanism of translational motion that involves successive pinning and depinning events at interfacial defects. The activation energy for depinning is estimated to be 0.1-1 eV. © 2013 American Physical Society.


Xiong Y.-H.,Wuhan University | Xiong Y.-H.,Peoples Hospital of Gansu Province | Yuan Z.,Nanchang University | He L.,Wuhan University
Asian Pacific Journal of Tropical Medicine | Year: 2013

Objective: To investigate the effects of estrogen (E2) level on regulatory T cells (Treg) in peripheral blood during pregnancy. Methods: A total of 30 healthy non-pregnant women were selected as control group, 90 pregnant women of early, middle and late pregnancy and 30 postpartum women at 1 month after parturition were selected as experimental groups including early pregnancy group, middle pregnancy group and late pregnancy group; the proportions of CD4+CD25+ Treg and CD4+CD25+CD127- Treg among CD4+T cells were detected by flow cytometry; the serum estrogen content in peripheral blood was detected by electrochemical immune luminescence method. Results: E2 level was coincident with the change of Tregs number during pregnancy. The estrogen content in peripheral blood increased gradually from early pregnancy to late pregnancy, then decreased significantly after parturition, and the level at 1 month after parturition down to the level in non- pregnancy group (P>0.05); the level of E2 in pregnancy groups were significantly higher than those in non- pregnancy group (P<0.01); and there were significant differences among early pregnancy group, middle pregnancy group and late pregnancy group (P<0.05). The proportions of CD4+ CD25+ Treg and CD4+ CD25+ CD127- Treg in pregnancy groups were significantly higher than those in non- pregnancy group (P<0.05), but decreased significantly after parturition, and there was no significant difference between non- pregnancy group and postpartum women group (P>0.05); the proportions in middle and late pregnancy groups were significantly higher than those in early pregnancy group (P<0.05), but decreased slightly in late pregnancy group, there was no significant difference between late pregnancy group and middle pregnancy group (P>0.05). There was correlation between Tregs number with estrogen level during pregnancy. The proportion of CD4+ CD25+ Treg and CD4+ CD25+ CD127- Treg were positively correlated with estrogen level. Conclusions: High proportion of CD4+ CD25+ Treg and CD4+CD25+CD127- Treg is closely related to the high level of E2 during pregnancy. It suggested that high level of estrogen may induce an increase of CD4+ CD25+ Treg in peripheral blood, and then influence the immune function of pregnant women. The results of this experiment might play an important role of estrogen in immune-modulation during pregnancy. © 2013 Hainan Medical College.


Liu Y.,Nanchang University | Xie Y.,Eastern Michigan University
Energy Economics | Year: 2013

This paper provides a comprehensive nonlinear analysis of asymmetric adjustment of the dynamic relationship between energy intensity and urbanization using the time series data of 1978-2010 in China at both the national and the macro regional levels. Two sets of unit root tests are applied first to check whether the variables of energy intensity and urbanization are heterogeneous with and without structural breaks, respectively. Cointegration tests are then applied to determine whether long-term relationships are present when structural breaks are or aren't accounted for. The asymmetric adjustment analyses are finally applied to examine how the variables in time-series respond to the deviations from the equilibrium through an integration of threshold vector error correction model (TVECM), and to examine how they respond to the co-existence of TVECM and the threshold. The findings of the systematic tests and analyses confirm the existence of non-linear causal relationships between the energy intensity and urbanization in China. Energy intensity has an asymmetric adjusting effect to urbanization in the whole country and the Central belt. An asymmetric adjustment running from the energy intensity to urbanization is also identified when structural breaks are accounted for, which occurred in 1988, 1993, 2000 and 2006. Furthermore, the two-regime threshold vector error correction model shows that the adjustment process of the energy intensity toward equilibrium is highly persistent when a threshold is reached. There exists a mean-reverting behavior, indicating that the energy intensity grows faster than the urbanization in China when the threshold is reached. © 2012 Elsevier B.V..


Xiao Y.-L.,Sun Yat Sen University | Peng S.,Sun Yat Sen University | Tao J.,Sun Yat Sen University | Wang A.-J.,Nanchang University | And 3 more authors.
American Journal of Gastroenterology | Year: 2010

OBJECTIVES:To determine the prevalence and symptom pattern of pathologic esophageal acid reflux (PEAR) in patients with functional dyspepsia (FD) using the Rome III criteria, and to explore the value of a proton pump inhibitor (PPI) test in distinguishing the patients with and those without PEAR among FD patients.METHODS:Consecutive FD patients who fulfilled the Rome III criteria without predominant typical reflux symptoms (i.e., heartburn or regurgitation) were enrolled. All patients underwent upper endoscopy and an ambulatory 24-h pH monitoring. PEAR was defined as the percentage total time for which a pH value <4 was> 4.2% in the distal esophagus. Then, patients were treated with rabeprazole 10 mg twice daily for 28 days. The symptom scores were measured by the frequency score multiplied by the severity scores of the predominant symptom before and at the end of the treatment, and the PPI test was defined as positive if the overall scores of the predominant dyspeptic symptom in the fourth week decreased by 50% compared with those of the baseline.RESULTS:One hundred eighty-six FD patients were enrolled, with predominant symptoms of epigastric pain (n68), epigastric burning (n=47), bothersome postprandial fullness (n=54), and early satiation (n17). The prevalence of PEAR was 31.7%, with the highest percentage (48.9%) in patients with epigastric burning as their predominant symptom. The prevalence of PEAR in patients with postprandial distress syndrome (PDS) and epigastric pain syndrome (EPS) were 36.6% (26/71) and 28.7% (33/115), respectively. Overall, 63.4% were positive for the PPI test; the rates were 51.5, 85.0, 66.7, and 41.1% in patients with epigastric pain, epigastric burning, bothersome postprandial fullness, and early satiation as their predominant symptoms, respectively ( x2= 17.59, P<0.001). The positive rates were 65.5 and 60.6% in patients with PDS and EPS, respectively ( x2=0.41, P=0.522). The sensitivity and specificity of the PPI test in distinguishing FD patients with PEAR was 83.1 and 45.7%, respectively.CONCLUSIONS:PEAR is present in almost one third of FD patients; the prevalence is ∼50% in those with epigastric burning. The PPI test has a limited value in distinguishing the FD patients with and those without PEAR. © 2010 by the American College of Gastroenterology.


Zhou L.,Nanchang University
2011 2nd International Conference on Mechanic Automation and Control Engineering, MACE 2011 - Proceedings | Year: 2011

The square truncated cone is processed by NC incremental forming in order to analyze the change law of metal texture. The experiment results show that a uniform thickness of the deformed region is maintained and in good accordance with that obtained by the sine law. The metal deformation law is searched by metallurgical analysis. The crystalline grain is stretched severely on the vertical section of the square truncated cone. The crystalline grain size is constant on the horizontal section of the square truncated cone. The metal shear deformation occurs in the square truncated cone. It is drawn that the NC incremental forming is a shear forming. The experiment is made to verify it. © 2011 IEEE.


Ju F.J.,Nanchang University
Environment, Energy and Applied Technology - Proceedings of the 2014 3rd International Conference on Frontier of Energy and Environment Engineering, ICFEEE 2014 | Year: 2015

This study puts forward electric vehicle intelligent service platform based on cloud computing. With an Internet user access channels for electric cars, electric car core business to achieve the user’s query function, and charging reservation, route planning, policies and regulations show, online service and other auxiliary functions, and provide the user mobile phone client access. The emphasis is based on the cloud computing architecture theory, build a service platform, the core service layer, service management layer, user interface to access layer software architecture, analysis of the key technology of the operation service platform. Put forward the private and hybrid cloud deployment model based on coupling. © 2015 Taylor & Francis Group, London.


Ju F.J.,Nanchang University
Environment, Energy and Applied Technology - Proceedings of the 2014 3rd International Conference on Frontier of Energy and Environment Engineering, ICFEEE 2014 | Year: 2015

With the development of society and economy, the radiation source as the key content of civilian non power nuclear technology has been widely applied in many fields of petroleum, chemical, paper making, cement, metallurgy, medical treatment, agriculture, in the meantime, also left a hidden danger to humans, the use of management is the problem of radiation source. Long term since, the monitoring work of radiation source has been in the artificial monitoring stage backward, radiation source is lost when the incident occurred; a colorless, tasteless and radioactive pollution are imperceptible; once the contaminated environment will be difficult to control and restore; radioactive source also has social sensitivity, the public has the abnormal fear of radiation, once the discovery of radioactivity pollution hazard, extremely easy to cause social unrest, effect of diazepam. So it has important significance and application value for monitoring social real-time reliable large amounts of radioactive source research on how the distribution of a wide range of different site environment. © 2015 Taylor & Francis Group, London.


Yang Z.,Nanchang University
International Journal of Simulation: Systems, Science and Technology | Year: 2015

This paper builds the power transformer diagnosis model based on the improved particle swarm optimization— support vector machine (MPSO-SVM). Speed update and particle self-adaptation self-variation are introduced to optimize the standard particle swarm algorithm, thus overcoming the defect of the standard particle swarm optimization algorithm and increasing the power transformer fault diagnosis accuracy rate of SVM. Through the analysis of the relationship between the transformer fault and the dissolved gas, the volume content of the dissolved gas of the transformer is adopted as the fault feature index. Through the experiment numerical analysis, results suggest that: the test sample recognition accuracy of the model parameters acquired by MPSO-SVM is higher than that acquired by the standard PSO by 17.86%. © 2015, UK Simulation Society. All rights reserved.


Chen W.Y.,Nanchang University
Applied Mechanics and Materials | Year: 2014

CDIO has become in recent years, guiding the teaching reform of advanced education concept, especially in the engineering personnel training mode and widespread application in the engineering curriculum.At home and abroad well-known colleges and universities according to the CDIO mode to cultivate students welcome by society and enterprises.Introducing the concept of CDIO architectural design teaching, research and establish a practice, pay attention to team collaboration and innovation of new course teaching mode. © (2014) Trans Tech Publications, Switzerland.


Wei C.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wen H.,CAS Beijing Institute of Geographic Sciences and Nature Resources Research | Wen H.,Nanchang University
Environmental Geochemistry and Health | Year: 2012

The aim of this study was to estimate the geochemical baseline concentrations of various heavy metals in the surface sediments of two large freshwater lakes in Taihu and Dianchi, China, and to assess the character and history of heavy metal contamination around the two lakes. Heavy metal concentrations in the sediments were obtained by field surveys and were supplemented with published data. The statistical methods of cumulative frequency and normalization were employed to obtain the baselines. The respective baseline concentrations for As, Sb, Hg, Co, Cr, Cu, Ni, Pb and Zn were 9. 92, 1. 67, 0. 14, 22. 62, 100. 56, 31. 63, 31. 97, 33. 05 and 97. 01 mg/kg, respectively, in Taihu, and 24. 60, 4. 29, 0. 25, 36. 78, 135. 68, 90. 05, 50. 76, 73. 56 and 208. 76 mg/kg, respectively, in Dianchi. The baseline concentrations of these heavy metals in Lake Taihu were equivalent to the pre-industrial concentrations determined from lakes in Sweden and Europe. Conversely, those in Lake Dianchi were much higher than the pre-industrial values. Li, Fe, Sc, Ti, V and Al were found to be the suitable reference elements for normalization, and one of these elements could be used to predict the baseline concentrations of heavy metals except Hg. Most of the heavy metals had one inflexion, and only Cu and Pb in Taihu, Sb, Pb and Zn in Dianchi, were found to have two inflexions in the cumulative curves, suggesting remarkable anthropogenic inputs of Cu and Pb in Taihu, Sb, Pb and Zn in Dianchi, which are generally consistent with the respective industrial structure around Taihu and Dianchi. © 2012 Springer Science+Business Media B.V.


Liu Y.,Nantong University | Liu S.Q.,Nanchang University | Zhou L.,Nantong University
Physics of Plasmas | Year: 2013

The Bohm criterion in a dusty plasma containing nonextensively distributed electrons and cold ions is investigated within the framework of probe model including the effects of dust charge fluctuation. It is shown that the critical Mach number upshifts with the decrease of electron nonextensive parameter (qe) and the increase of the ion-to-electron number density ratio (Rn) when the effects of dust charge fluctuation are out of consideration. Once the effects of dust charge fluctuation are included, with the increase of Rn, the critical Mach number increases first, then decreases. The slop of the critical Mach number curves in the region R n 1 for q e > 1 becomes more gradual than that for q e 1. When critical Mach number is defined with respect to modified ion acoustic wave speed, it should be larger than unity in the case free of dust charge fluctuation. Whereas when R n 1, it may be smaller than unity due to the effect of dust charge fluctuation. © 2013 American Institute of Physics.


Pu S.,Jiangxi Science and Technology Normal University | Zheng C.,Nanchang University | Sun Q.,Jiangxi Science and Technology Normal University | Liu G.,Jiangxi Science and Technology Normal University | Fan C.,Jiangxi Science and Technology Normal University
Chemical Communications | Year: 2013

The weak intramolecular F⋯N and S⋯N interactions in the novel pyridine-containing perfluorodiarylethenes achieved high cyclization quantum yields in solutions. While the F⋯N interactions stabilize the photoreactive conformation, the S⋯N contacts contribute from the energetic aspect. © 2013 The Royal Society of Chemistry.


Zhang R.,Nanchang University | Chang P.-C.,Yuan Ze University | Wu C.,Tsinghua University
International Journal of Production Economics | Year: 2013

This paper studies a job shop scheduling problem with two new objective functions based on the setup and synergy costs besides the traditional total weighted tardiness criterion. The background is found in the real-world situation of a commercial vehicle producer, where the reduction of manufacturing costs has become a significant concern like in many heavy industry firms. The cost-related objective functions have been modeled in a quite general way so that they can also be applied to other similar types of production. To tackle this multi-objective scheduling problem, the paper presents a Pareto-based genetic algorithm incorporating a local search module, which utilizes the neighborhood properties specifically developed for each objective function. The computational experiments on both real-world and randomly generated scheduling instances verify the effectiveness of the proposed approach. The research presented in this paper could shed some light on the modeling and heuristic solving of practical production scheduling problems. © 2012 Elsevier B.V.


The early determination of family for a newly found enzyme molecule becomes important because it is directly related to the detail information about which specific target it acts on, as well as to its catalytic process and biological function. Unfortunately, it is still a hard work to distinguish enzyme classes by experiments. With an enormous amount of protein sequences uncovered in the genome research, it is both challenging and indispensable to develop an automatic method for fast and reliably classifying the enzyme family. Using the concept of Chou's pseudo amino acid composition, we developed a new method that coupled discrete wavelet transform with support vector machine based on the amino acid hydrophobicity to predict enzyme family. The overall success rate obtained by the 10-cross-validation for the identification of the six enzyme families was 91.9%, indicating the current method could be an effective and promising high-throughput method in the enzyme research.


Objective: To explore the effect of bone marrow mesenchymal stem cells (MSCs) engraftment on lung tissue at early stage of smoke inhalation injury in rabbits. Methods: MSCs were proliferated by the method of whole marrow culture and identified by flow cytometry. Forty-eight rabbits were randomly divided into smoke inhalation group (S group) and MSCs group (M group) after reproduction of rabbit smoke inhalation injury model. 10 ml of phosphate buffer saline (PBS) containing 1 × 10 7/ml MSCs was intravenously injected in M group, meanwhile 10 ml PBS was injected intravenously in S group. Eight rabbits were sacrificed at 2, 6 and 24 hours after intervention, and the lung tissue was harvested for morphological and pathological observation, and lung injury score was used to evaluate smoke inhalation injury. Results: Cultured cells were confirmed to be MSCs with flow cytometry. Lung injury in rabbits of M group was less serious in morphology and histopathology than that in S group. Though there was no significance in lung injury score between M group and S group at 2 hours after injury (4.0±0.7 vs. 4.5±0.6, P>0.05), the lung injury scores in M group at 6 hours and 24 hours after injury were significantly lower than those in S group (6 hours, 6.1±0.9 vs. 8.2±0.9, 24 hours, 4.6±0.9 vs. 10.4±0.8, both P<0.01). Conclusion: Intravenous engraftment of MSCs could ameliorate lung injury induced by smoke inhalation, and improve lung injury score significantly.


Wu H.L.,Nanchang University
Environment, Energy and Applied Technology - Proceedings of the 2014 3rd International Conference on Frontier of Energy and Environment Engineering, ICFEEE 2014 | Year: 2015

This article analyzes the demand of the unmanned vehicle, made clear in the road traffic, and the basic requirements of the unmanned vehicle development present situation at home and abroad, and put forward the unmanned vehicle control and planning the overall scheme of the system control is divided into the underlying control, GPS navigation and laser radar environment perception of three parts. It also introduces the design principle of unmanned drone, analyzed the security of the intelligent unmanned and the design of the driverless cars running, analyzed the influence of the intelligent unmanned social benefit analysis, and the prospects of intelligent driverless cars in the future were discussed. © 2015 Taylor & Francis Group, London.


Duanmu J.,Yale University | Cheng J.,Yale University | Cheng J.,Nanchang University | Xu J.,Yale University | And 2 more authors.
British Journal of Cancer | Year: 2011

Background:The purpose of this study was to test a novel, dual tumour vascular endothelial cell (VEC)- and tumour cell-targeting factor VII-targeted Sn(IV) chlorin e6 photodynamic therapy (fVII-tPDT) by targeting a receptor tissue factor (TF) as an alternative treatment for chemoresistant breast cancer using a multidrug resistant (MDR) breast cancer line MCF-7/MDR.Methods:The TF expression by the MCF-7/MDR breast cancer cells and tumour VECs in MCF-7/MDR tumours from mice was determined separately by flow cytometry and immunohistochemistry using anti-human or anti-murine TF antibodies. The efficacy of fVII-tPDT was tested in vitro and in vivo and was compared with non-targeted PDT for treatment of chemoresistant breast cancer. The in vitro efficacy was determined by a non-clonogenic assay using crystal violet staining for monolayers, and apoptosis and necrosis were assayed to elucidate the underlying mechanisms. The in vivo efficacy of fVII-tPDT was determined in a nude mouse model of subcutaneous MCF-7/MDR tumour xenograft by measuring tumour volume.Results:To our knowledge, this is the first presentation showing that TF was expressed on tumour VECs in chemoresistant breast tumours from mice. The in vitro efficacy of fVII-tPDT was 12-fold stronger than that of ntPDT for MCF-7/MDR cancer cells, and the mechanism of action involved induction of apoptosis and necrosis. Moreover, fVII-tPDT was effective and safe for the treatment of chemoresistant breast tumours in the nude mouse model.Conclusions:We conclude that fVII-tPDT is effective and safe for the treatment of chemoresistant breast cancer, presumably by simultaneously targeting both the tumour neovasculature and chemoresistant cancer cells. Thus, this dual-targeting fVII-tPDT could also have therapeutic potential for the treatment of other chemoresistant cancers. © 2011 Cancer Research UK All rights reserved.


Wu X.,Nanchang University
Research in Astronomy and Astrophysics | Year: 2010

A global relationship between cosmological time and Belinskii-Khalatnikov- Lifshitz (BKL) time during the entire evolution of the Mixmaster Bianchi IX universe is used to explain why all the Lyapunov exponents are zero at the BKL time. The actual reason is that the domain of the cosmological time is finite as the BKL time runs from minus infinity to infinity. © 2010 National Astronomical Observatories of Chinese Academy of Sciences and IOP Publishing Ltd.


The effectiveness of fixatives for fixing biological specimens has long been widely investigated. However, the lowest concentrations of fixatives needed to completely fix whole cells or various cellular structures remain unclear. Using real-time imaging and quantification, we determined the lowest concentrations of glutaraldehyde (0.001-0.005, ~0.005, 0.01-005, 0.01-005, and 0.01-0.1 %) and formaldehyde/paraformaldehyde (0.01-0.05, ~0.05, 0.5-1, 1-1.5, and 0.5-1 %) required to completely fix focal adhesions, cell-surface particles, stress fibers, the cell cortex, and the inner structures of human umbilical vein endothelial cells within 20 min. With prolonged fixation times (>20 min), the concentration of fixative required to completely fix these structures will shift to even lower values. These data may help us understand and optimize fixation protocols and understand the potential effects of the small quantities of endogenously generated aldehydes in human cells. We also determined the lowest concentration of glutaraldehyde (0.5 %) and formaldehyde/paraformaldehyde (2 %) required to induce cell blebbing. We found that the average number and size of the fixation-induced blebs per cell were dependent on both fixative concentration and cell spread area, but were independent of temperature. These data provide important information for understanding cell blebbing, and may help optimize the vesiculation-based technique used to isolate plasma membrane by suggesting ways of controlling the number or size of fixation-induced cell blebs.


Wang Q.,Chongqing University | Wang Q.,Nanchang University | Liu F.,Chongqing University | Li C.,Chongqing University
Journal of Cleaner Production | Year: 2013

Increasing pressures from energy price and environmental directive force the manufacturing enterprises to consider and initiate the implementation of energy assessment and energy quota practices to improve both their economic benefit and environmental performance. Against this background this paper presents an integrated method to evaluate energy efficiency in machining workshop. The integrated features of the assessing method are reflected in three aspects: (1) In this evaluation system, the energy profile of machining workshop is viewed from the machine tool layer, manufacturing unit layer, task layer and workshop layer to reveal the energy performance inside the workshop completely. (2) The assessing indexes for each layer include both effective energy indicator and Specific Energy Consumption (SEC) indicator. (3) An integrated calculation method of energy indexes is introduced, which combines off-line experiments with theoretical formulas. To verify its feasibility and validity, the assessment method is applied to a small machining workshop. The assessing results showed that the assessment method is helpful in providing support for machining scheme selection, energy saving discovery and energy quota allocation in plant, which has significance in practice. © 2013 Elsevier Ltd. All rights reserved.


Xiao S.-B.,Nanchang University
Applied Mechanics and Materials | Year: 2014

With the continuous development of computer technology, the technology in designing and developing 3D games has been more and more mature. Compared to the traditional ones, 3D games present more real screen effects and stronger visual impact due to its adopting the concept of stereo space coordinates, increasing the arbitrariness of space operation and its own attraction. By applying media video technology to 3D table tennis games, players can hit the ball with the racket to implement the move of the ball in the game scene. To achieve the ball's real-time depiction, every frame in the game must be updated. An outstanding 3D game cannot be developed without an excellent 3D game engine. The complex graphic algorithm of the game is encapsulated in modules efficiently while simple and effective SDK interface, powerful editor and matching third-party plug-ins are provided externally. Meanwhile, it possesses the function in network, database and script, etc, making the development of 3D games easier and of high quality. Numerous UI (graphical interfaces) are offered in the whole game to help players understand and learn the game. The game is operated so easily that it can be well played only through click, which simplifies the fussy operation of regular ones and provides players with more enjoyment. © (2014) Trans Tech Publications, Switzerland.


Liu Y.,Nanchang University
Aquatic Ecosystem Health and Management | Year: 2014

Urban rivers and lakes play a significant role in providing ecosystem services, such as water supply, purification, nutrient retention, recreation, aesthetics, and more. However, there is no widely-accepted methodology for how to dynamically evaluate the ecosystem service values of urban rivers and lakes. Using data from survey and remote sensing of Nanchang City, China, this article constructs a conceptual framework based on the Millennium Ecosystem Assessment to propose an integrated approach to evaluate the ecosystem service values of urban rivers and lakes. Furthermore, the article employs a GIS-based Markov chain model to predict the future probable distribution pattern of land use in Nanchang City, while it uses an artificial neural network model to simulate the potential changing of ecosystem service values. The Millennium Ecosystem Assessment-based dynamic evaluation shows that in the first period of 1989-1999, provisioning services are dominant, followed by regulating services, supporting services and cultural services, while during the second period of 1999-2008, regulating services rank firstly in the total change of ecosystem service values, followed by supporting services, cultural services and provisioning services. The artificial neural network-based simulation indicates that the total will slightly increase in line with a small undulation in regulating service values, whilst the most changes brought by the provisioning services will be stable. This study is intended to serve as a tool to be used in decision making for proper and informed urban aquatic ecosystem management. © 2014 Copyright © 2014 AEHMS.


Peng X.-L.,Nanchang University
Acta Crystallographica Section E: Structure Reports Online | Year: 2010

In the title compound, [Cu(C16H11BrN 2)(C18H33P)]BF4, the CuI atom is three-coordinated in a distorted trigonal configuration by two N atoms from the 6-(4-bromo-phen-yl)-2,2'-bipyridine ligand and a P atom from the tricyclo-hexyl-phosphine ligand. In addition, a weak anion⋯CuI inter-action with a nearest F⋯Cu separation of 2.696 (5) Å is found.


Lu P.,Nanchang University
Acta biochimica et biophysica Sinica | Year: 2013

PKZ, protein kinase containing Z-DNA domains, is a novel member of the vertebrate eIF2α kinase family. Containing a catalytic domain in C-terminus and two Z-DNA binding domains (Zα1 and Zα2) in N-terminus, PKZ can be activated through the binding of Zα to Z-DNA. However, the regulatory function of PKZ Zα remains to be established. Here, to understand the impact of PKZ Zα on DNA conformational transition, wild-type Zα1Zα2 and 11 mutant proteins were expressed and purified. At the same time, several different lengths of DNA hairpins-d(GC)nT4(GC)n (n = 2-6) and an RNA hairpin-r(GC)6T4(GC)6 were synthesized. The effects of Zα1Zα2 and mutant proteins on the conformation of these synthetic DNA or RNA hairpins were investigated by using circular dichroism spectrum and gel mobility shift assays. The results showed that DNA hairpins retained a conventional B-DNA conformation in the absence of Zα1Zα2, while some of the DNA hairpins (n≥3) were converted to Z-conformation under Zα1Zα2 induction. The tendency was proportionally associated with the increasing amount of GC repeat. In comparison with Zα1Zα2, Zα1Zα1 rather than Zα2Zα2 displayed a higher ability in converting d(GC)6T4(GC)6 from B- to Z-DNA. These results demonstrated that Zα1 sub-domain played a more essential role in the process of B-Z conformational transition than Zα2 sub-domain did. Mutant proteins (K34A, N38A, R39A, Y42A, P57A, P58A, and W60A) could not convert d(GC)6T4(GC)6 into Z-DNA, whereas S35A or K56A retained some partial activities. Interestingly, Zα1Zα2 was also able to induce r(GC)6T4(GC)6 RNA from A-conformation to Z-conformation under appropriate conditions.


Li S.Y.,National University of Defense Technology | Zhang S.F.,National University of Defense Technology | Cai H.,National University of Defense Technology | Chen X.Q.,National University of Defense Technology | Deng X.H.,Nanchang University
Journal of Geophysical Research: Space Physics | Year: 2013

In this paper, we report the observations and statistical characteristics of tripolar electrostatic solitary waves (ESWs) along the plasma sheet boundary layer near the magnetic reconnection X line in the near-Earth magnetotail. Within reconnection diffusion region, the tripolar ESWs are ample and are continuously observed during one burst interval (8.75 s) of the Geotail/WaveForm Capture in the neutral plasma sheet where β > 1 on 10:20 UT, 2 February 1996. The tripolar ESW is suggested to be one kind of steady-going solitary structure. More than 200 waveforms with clear tripolar characteristics are differentiated for statistical analysis, and result shows that (1) their amplitude is within 100->500 μV/m, with an average amplitude of about 254 μV/m; (2) the pulse width of the tripolar ESWs is 0.5-1.0 ms, with an average value of about 0.75 ms; (3) it is asymmetrical in both the amplitude and pulse width of the tripolar ESWs: most part of the tripolar ESWs (about 76.5%) are asymmetrical in the amplitude of one hump and the other one, and more than 75% (about 177 amount the 236 waveforms) of the tripolar ESWs are asymmetrical in the time duration of the two humps in the waveform; (4) most of the tripolar ESWs are with the potential humps of 10-60 mV, small ratio of them with potential humps larger than 100 mV. The tripolar ESWs with net potential drop of about 10-50 mV can be interpreted as "weak" double layers. The possible generation mechanism of tripolar ESWs and their role in reconnection are discussed by studying the particle distribution during which the tripolar ESWs are continuously observed. The observation of tripolar ESWs presents evidence of complex structure of electron holes within the reconnection diffusion region and is helpful to the understanding of the energy release process of reconnection. Key Points first observation of tri-polar ESWs associated with the magnetic reconnection statistical analyses of tri-polar ESWs in detail asymmetry both in the amplitude and pulse width of the tri-polar ESWs ©2013. American Geophysical Union. All Rights Reserved.


Zhang X.-H.,Fudan University | Liu S.-S.,Fudan University | Yi F.,Fudan University | Zhuo M.,Kings College | And 2 more authors.
Molecular Brain | Year: 2013

Hippocampal N-methyl-D-aspartate receptor (NMDAR) is required for spatial working memory. Although evidence from genetic manipulation mice suggests an important role of hippocampal NMDAR NR2B subunits (NR2B-NMDARs) in spatial working memory, it remains unclear whether or not the requirement of hippocampal NR2B-NMDARs for spatial working memory depends on the time of spatial information maintained. Here, we investigate the contribution of hippocampal NR2B-NMDARs to spatial working memory on delayed alternation task in T-maze (DAT task) and delayed matched-to-place task in water maze (DMP task). Our data show that infusions of the NR2B-NMDAR selective antagonists, Ro25-6981 or ifenprodil, directly into the CA1 region, impair spatial working memory in DAT task with 30-s delay (not 5-s delay), but severely impair error-correction capability in both 5-s and 30-s delay task. Furthermore, intra-CA1 inhibition of NR2B-NMDARs impairs spatial working memory in DMP task with 10-min delay (not 30-s delay). Our results suggest that hippocampal NR2B-NMDARs are required for spatial working memory in long-delay task, whereas spare for spatial working memory in short-delay task. We conclude that the requirement of NR2B-NMDARs for spatial working memory is delay-dependent in the CA1 region. © 2013 Zhang et al.; licensee BioMed Central Ltd.


To investigate the effects of lanthanum chloride on proliferation and migration activity of human cervical cancer cells in vitro which may be a new anti-cervical cancer drug and provide experimental data for cervical cancer treatment. HeLa cells cultured in vitro were divided into two groups: experimental group and control group. In experimental group, the cells were respectively treated with lanthanum chloride at different concentrations, 5, 50 and 100 μmol/L, while the cells in the control group were not treated with lanthanum chloride. The cell growth was observed by inverted microscope and the morphology changes of the cells were observed by the laser scanning confocal microscope (LSCM). Proliferation of HeLa cells in the two groups was detected by methyl thiazolyl tetrazolium (MTT) test; apoptosis rate was analyzed by flow cytometry (FCM). Cell migration test was applied to observe the effect of lanthanum chloride on migration. Reverse transcription (RT)-PCR was employed to evaluate the effects of lanthanum chloride on proliferation gene (cyclinD1), anti-apoptosis gene (zinc finger protein A20) and migration-related gene (matrix metalloproteinase 9, MMP-9). The status of cell growth was observed under the inverted microscope: with the increased of the lanthanum chloride concentrations, the cell density of reduced, the granule in cytoplasm increased, color intensifying and intercellular space enlarged; some cells became rounding and dead, floating in the culture media; the exfoliated cells increased gradually in the experimental groups. While In the control group, the cells grew adherently, with clear morphology and plump cytoplasm, and adjacent cell grew in lamellar. Observed with LSCM: the nuclear chromatin condensated and marginated with the volume of nuclear decreased in experimental groups. With the increase of the lanthanum chloride concentrations, nuclei in the experimental groups became pyknotic and then underwent karyorrhexis. However, the nuclear of the cells in control group were inact. The growth inhibition rates of lanthanum chloride groups (5, 50, 100 μmol/L) were 24%, 51% and 78%, respectively, in which each was significantly higher than that of the control group (P < 0.05); the apoptosis rates of lanthanum chloride group were (4.91 ± 0.39)%, (7.30 ± 0.71)% and (13.48 ± 0.92)%, respectively, which were all significantly higher than that of the control group [(0.89 ± 0.11)%, P < 0.01]. The migration ability of the cells was also decreased by the treatment of lanthanum chloride, the number of migrated cells in lanthanum chloride groups were 22.2 ± 4.3, 12.0 ± 3.2 and 7.8 ± 2.6 respectively, which were all significantly lower than that of the control group (41.2 ± 5.4, P < 0.01). The expression of genes of cyclinD1, A20 and MMP-9, were all decreased by the treatment of lanthanum chloride in a dose-dependent manner. Lanthanum chloride can inhibit the proliferation and migration of cervical cancer cells, and induce apoptosis by down-regulating cyclinD1, A20, and MMP-9 expressions in vitro.


Zhang R.,Nanchang University
International Journal of Advancements in Computing Technology | Year: 2011

Job shop scheduling is an important decision process in contemporary manufacturing systems. Most existing research has been focused on the minimization of makespan (i.e. the completion time of all jobs). However, due date related performances are actually crucial for maintaining a high service reputation in the competitive market. In this paper, we propose a novel particle swarm optimization (PSO) algorithm for solving the job shop scheduling problem with the objective of minimizing total weighted tardiness. A local search procedure based on processing time perturbations is designed and embedded into the framework of PSO. The computational experiments for a wide range of test instances show that the hybrid PSO converges fast to high-quality solutions.


Chen H.,Nanchang University | Hu P.,Hubei University
IET Control Theory and Applications | Year: 2013

This article mainly studies the problem of the exponential stability for singular systems with two interval timevarying delays. By constructing a modified Lyapunov-Krasovskii functional (LKF) and utilising a convex polyhedron method to estimate the derivative of LKF, some new delay-dependent criteria can be established in terms of linear matrix inequalities. Compared with some existing literatures, the novelties in this study are that the needed decisive variables are fewer and the obtained delay-dependent stability criteria are less conservative. Finally, two illustrative numerical examples are given to show the effectiveness of the derived results. © The Institution of Engineering and Technology 2013.


Xu X.A.,Nanchang University
Advanced Materials Research | Year: 2014

This paper mainly studies the present distributed technology and database applications, with examples for analysis, analysis of the current computer technology in the field of distributed technology. And based on the theory of database, distributed technology and database technology, database technology is to call SQL, distributed research. From the analysis of the distributed computer field, the combination of the database and application the paper was written. © (2014) Trans Tech Publications, Switzerland.


Zhang R.,Nanchang University
International Journal of Digital Content Technology and its Applications | Year: 2011

In this paper, we aim at solving the job shop scheduling problem with pending due dates. Due date quotation is an important decision process for contemporary companies adopting the MTO (make-toorder) policy. Although the assignment of due dates is usually performed separately with production scheduling, there exist strong interactions between the two tasks. Therefore, we integrate these two decisions into one optimization model. In view of the high complexity, we propose a differential evolution algorithm to solve the integrated job shop scheduling problem. The superiority of this approach is revealed by extensive computational experiments.


Zhang R.,Nanchang University
International Journal of Advancements in Computing Technology | Year: 2011

Job shop scheduling is a significant decision problem in computer-integrated manufacturing systems. Most existing research has been focused on the sole objective of minimizing the makespan (i.e. the completion time of all jobs). However, due date related performances are also crucial for contemporary companies in the competitive market. In this paper, we propose a multi-objective particle swarm optimization (PSO) algorithm for solving the job shop scheduling problem with the objectives of minimizing the makespan as well as the total weighted tardiness. The concept of Pareto dominance has been used as the mechanism for comparing different solutions. The computational experiments on a wide range of test instances show that the multi-objective PSO is effective.


Zhong Z.-Y.,Nanchang University | Tang Y.,Peoples Hospital of Gansu Province
Cellular Physiology and Biochemistry | Year: 2016

Background/Aims: High glucose-induced oxidative damage to endothelial cells plays a central role in the pathogenesis of diabetic vascular complications. This study was undertaken to explore the role of periostin in high glucose-induced endothelial cell apoptosis and associated molecular mechanisms. Methods: Human umbilical vein endothelial cells (HUVECs) were exposed to high glucose (33.3 mmol/L) and examined for the expression of periostin. The effects of periostin upregulation on high glucose-induced apoptosis, mitochondrial dysfunction, and reactive oxygen species (ROS) production were determined. The activation of nuclear factor erythroid 2-related factor 2 (Nrf2)/heme oxygenase-1 (HO-1) by periostin was checked. HO-1 knockdown experiments were done to confirm its role in the action of periostin in high glucose-exposed HUVECs. Results: High glucose significantly upregulated the expression of periostin in HUVECs. Enforced expression of periostin attenuated high glucose-induced apoptosis in HUVECs, as determined by TUNEL staining and caspase-3 activity assay. Periostin overexpression prevented loss of Δψm, release of mitochondrial cytochrome c, and dysregulation of Bcl-2 and Bax in high glucose-exposed HUVECs. Periostin upregulation suppressed high glucose-induced ROS generation and activated the Nrf2/HO-1 signaling. HO-1 silencing restored high glucose-induced ROS generation and apoptotic response in periostin-overexpressing HUVECs. Conclusion: Periostin mitigates high glucose-induced mitochondrial apoptosis in endothelial cells, via activation of Nrf2/HO-1 signaling and reduction of ROS formation. Further studies are warranted to explore the therapeutic potential of periostin in diabetic vascular complications. © 2016 The Author(s) Published by S. Karger AG, Basel.


Chen H.,Nanchang University
IET Control Theory and Applications | Year: 2013

In this study, the problem for the robustly exponential stability in mean square moment of uncertain neutral stochastic linear system with mixed time-varying delays is considered. By constructing an augmented Lyapunov-Krasovskii functional and utilising a convex polyhedron method, some new delay-dependent exponential stability criteria for such system are established in forms of linear matrix inequalities, which have less conservatism. Finally, three illustrative numerical examples are given to show the effectiveness of the obtained results. © The Institution of Engineering and Technology 2013.


Nie X.,Nanchang University
Advanced Materials Research | Year: 2012

The conventional perturbation and observation (P&O) method is combined by the target tracking technique of data fusion, the adaptive multi-mode MPPT control algorithm is put forward for the first time. The reasonable and long step is selected to insure tracking velocity, the target tracking algorithm is adoptted for weaken and restrain vibration, the target maneuvering detection technique is put to use to judge whether the system is "lose control " in fast variation environments, the repeat starting up perturbation and observation (P&O) method in order to strengthen system stability. The experimental result shows the correctness and validity of the method. © (2012) Trans Tech Publications.


Shao Y.,Nanchang University
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica | Year: 2012

To investigate the clinical effect of spanishneedles leaves on middle and severe xerophthalmia of menopausal females. This study was a prospective random controlled trial. Ninty-six menopausal females diagnosed with xerophthalmnia (aged from 40 to 50) were randomly divided into in two groups: group A' the spanishneedles leaves group (n=48) and group B' the control group (n=48). Both groups were treated with Forte eye drops. All patients were detected at 3, 7, 28 h before and after treatment to evaluate subjective symptoms, OSDI and four tear film indicators. Variance analysis and differential analysis on sample average or median were made on both groups before and after treatment. There were no significant difference in symptom and diction indicators between both groups before treatment. For 28 d after treatment, among middle and severe xerophthalmia samples of the spanishneedles leaves group, the mean differences showed significant improvement compared with that before treatment , OSDI and four tear film indicators also showed improvement to varying degrees. For 28 d after treatment, among middle and severe xerophthalmia samples of the vitamin C group, the mean differences showed no significant improvement compared with that before treatment , OSDI and four tear film indicators also showed no remarkable improvement. There were significant differences in OSDI, BUT, SIT, height of tear meniscus and FL between both groups. Spanishneedles leaves can effectively improve symposiums and signs of middle and severe xerophthalmia among menopausal females and thus showing clinical significance to some extent.


Chen P.X.,University of Guelph | Wang S.,University of Guelph | Nie S.,Nanchang University | Marcone M.,University of Guelph
Journal of Functional Foods | Year: 2013

A great mystique and aura surrounds Cordyceps sinensis (syn.: Cephalosporium sinensis), an endoparasitic fungus which has claims of anti-cancer and anti-aging properties. Much research has been conducted over the years on crude extracts and its bioactivity. More research is now focused on culturing C. sinensis and on isolating and identifying pure compounds novel to C. sinensis in an attempt to alleviate strain on demand for the natural fungi. Several polysaccharides, nucleosides and sterols all have had reports of promoting health both in vitro and in vivo. Specific and novel compounds which are characteristic to C. sinensis are emerging with reports of two new epipolythiodioxopiperazines, gliocladicillins A and B capable of inhibiting growth of HeLa, HepG2 and MCF-7 tumor cells. Exclusive to natural C. sinensis, five constituents of cordysinin (A-E) has also been reported for the first time and has been linked to anti-inflammatory properties. Although it may still be premature to believe these results should translate into pharmaceutical use, there is sufficient evidence to warrant further research. © 2013.


Li M.H.,Nanchang University
Zhonghua yi xue za zhi | Year: 2010

OBJECTIVE: To analyze the clinical features, surgical strategy and management outcomes of petroclival meningioma invading into cavernous sinus. METHODS: Fifteen cases with petroclival meningioma invading into cavernous sinus were retrospectively analyzed. The presigmoidal approach was selected to remove tumors. The surgical strategy for tumor in cavernous sinus was partial resection combined with radiosurgery. Postoperative cranial nerve function and patient survival status were analyzed. RESULTS: The main symptoms of subtype of petroclival meningiomas were headache, abducens nerve palsy and trigeminal neuropathy. Gross total tumor removal was achieved in 13 cases and more than 90% resection in 2 cases. There was no operative death. Nine cases suffered from new postoperative cranial nerve deficits. After a follow-up of 6 - 59 months, complete improvement was achieved in oculomotor nerve deficits, much improvement in VII nerve deficit, but V and VI nerve function deficits improved slightly. The tumor progression-free survival rate was 86.7%. CONCLUSION: Rational surgical strategy to petroclival meningiomas invading into cavernous sinus should be suggested to reduce the operative morbidity and improve the survival quality of these patients.


Zhang Q.,Nanchang University
Research Journal of Chemistry and Environment | Year: 2014

The farmland soils surrounding scale pig farms in Nanchang were sampled and the content of soil heavy metals and its physical and chemical properties were measured. The Pearson Correlations between the content of heavy metals and soil physicochemical property were analyzed through SPSS 18. The farmland soil was generally acidic; the content of soil organic matter was above the third grade; the content of available nitrogen was between the grades fifth and sixth and the content of available phosphorus was classified as the rich grade. The farmland soils surrounding scale pig farms were suitable for crop growing. The average content of As, Cr, Cu and Zn was within the standard while Cd, Ni and Pb was out of the standard. The competitive pollution index was greater than 1 which showed that the farmland soils were in slightly polluted grade. Soil available nitrogen, available phosphorus and soil oxidation-reduction potential were negatively correlated while soil available nitrogen and available phosphorus were positively correlated. The correlation among heavy metals As, Cd, Pb, Cu and Zn was highly significant or significant, but the correlation among Cr, Ni and other heavy metals was not relevant. The available phosphorus and oxidation-reduction potentials have an obvious influence on the distribution of heavy metals. The available nitrogen has a non-significant influence on the distribution of heavy metals while the soil water content, pH and soil organic have no influence on the distribution of heavy metals.


Luo X.,University of Rochester | Luo X.,Hangzhou Normal University | Huang L.,Nanchang University | Huang L.,Gannan Medical University | And 6 more authors.
Schizophrenia Bulletin | Year: 2014

Recent genome-wide association studies have identified many promising schizophrenia candidate genes and demonstrated that common polygenic variation contributes to schizophrenia risk. However, whether these genes represent perturbations to a common but limited set of underlying molecular processes (pathways) that modulate risk to schizophrenia remains elusive, and it is not known whether these genes converge on common biological pathways (networks) or represent different pathways. In addition, the theoretical and genetic mechanisms underlying the strong genetic heterogeneity of schizophrenia remain largely unknown. Using 4 well-defined data sets that contain top schizophrenia susceptibility genes and applying protein-protein interaction (PPI) network analysis, we investigated the interactions among proteins encoded by top schizophrenia susceptibility genes. We found proteins encoded by top schizophrenia susceptibility genes formed a highly significant interconnected network, and, compared with random networks, these PPI networks are statistically highly significant for both direct connectivity and indirect connectivity. We further validated these results using empirical functional data (transcriptome data from a clinical sample). These highly significant findings indicate that top schizophrenia susceptibility genes encode proteins that significantly directly interacted and formed a densely interconnected network, suggesting perturbations of common underlying molecular processes or pathways that modulate risk to schizophrenia. Our findings that schizophrenia susceptibility genes encode a highly interconnected protein network may also provide a novel explanation for the observed genetic heterogeneity of schizophrenia, ie, mutation in any member of this molecular network will lead to same functional consequences that eventually contribute to risk of schizophrenia. © 2013 The Author.


Wu J.-P.,Beijing Normal University | Cao Y.,Beijing Normal University | Kuang X.-M.,Nanchang University | Li W.-J.,Beijing Normal University
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2011

In this Letter we study 3+1 holographic superconductors with Weyl corrections. We find that the critical temperature of a superconductor with Weyl corrections increases as we amplify the Weyl coupling parameter γ, indicating the condensation will be harder when the parameter γ decreases. We also calculate the conductivity and the ratio of gap frequency over critical temperature ωg/Tc numerically for various coupling parameters. We find that the ratio ωg/Tc becomes larger when the Weyl coupling parameter γ decreases. We also notice that when γ<0 there is an extra spike that appears inside the gap. © 2011 Elsevier B.V.


Chen Y.,Nanchang University
Advanced Materials Research | Year: 2011

Along with the development of power electronic technology, various inverters are widely used in all sectors. the advanced modern control theory and methods have been applied in the inverter, which made the stability and reliability for the inverter have improved greatly. In this paper analyses the working principle for SPWM inverter that used voltage and current cut-loop PID control strategy, in the voltage loop and current loop make use of its transfer function to both no-load and full load conditions for digital simulation, and get different Bode diagrams, meanwhile also analyses the different simulation results for system that without add PID controller and join PID controller, with the analyze results can determine the open-loop frequency characteristics of various parameters for the closed- loop system, and to ensure the output inverter to achieve the intended targets. © 2011 Trans Tech Publications.


Guo L.,Peking University | Xie B.,Nanchang University | Mao Z.,Peking University
International Journal of Molecular Sciences | Year: 2012

Autophagy is a highly regulated intracellular process involved in the turnover of most cellular constituents and in the maintenance of cellular homeostasis. In this study, we show that the activity of autophagy increases in H 2O 2 or RasV12-induced senescent fibroblasts. Inhibiting autophagy promotes cell apoptosis in senescent cells, suggesting that autophagy activation plays a cytoprotective role. Furthermore, our data indicate that the increase of autophagy in senescent cells is linked to the activation of transcription factor FoxO3A, which blocks ATP generation by transcriptionally up-regulating the expression of PDK4, an inhibitor of pyruvate dehydrogenase complex, thus leading to AMPK activation and mTOR inhibition. These findings suggest a novel mechanism by which FoxO3A factors can activate autophagy via metabolic alteration. © 2012 by the authors; licensee MDPI, Basel, Switzerland.


Zhang Y.,Wuhan University of Science and Technology | Liu Z.,Wuhan University of Science and Technology | Fang H.,Wuhan University of Science and Technology | Chen H.,Nanchang University
Information Sciences | Year: 2013

This paper is concerned with fault detection for a class of complex networked control systems. By introducing transmission matrix, nonlinear delayed Markovian jump systems model with partially unknown transition probabilities are established by multiple channels data transmission framework. Based on the obtained model, mode-dependent fault detection filters are used for residual generator, the addressed fault detection problem is converted into nonlinear H∞ attenuation problem. Then the desired mode-dependent fault detection filters are constructed in terms of linear matrix inequalities such that the fault detection systems are stochastically stable with H ∞ attenuation level. A numerical example is given to demonstrate the effectiveness of the proposed design approach. © 2012 Elsevier Inc. All rights reserved.


Nie X.-H.,Nanchang University
Dianli Xitong Baohu yu Kongzhi/Power System Protection and Control | Year: 2013

Strong tracking Unscented Kalman filter algorithm is an estimation method of approximating nonlinear distribution by the Unscented strategy and tracking strongly system status mutation. The algorithm combines the advantage of strong tracking algorithm robustness, high accuracy of Unscented transform and simple realization. In allusion to the photovoltaic system maximum power point misjudgment problem under partially shaded conditions, a new MPPT control strategy is proposed by combining fixed voltage method with strong tracking Unscented Kalman filter (STUKF) algorithm. The voltage range of the maximum power point is determined by the fixed voltage method. In this voltage range, the small-step control voltage is adopted, the instantaneous power is taken as the estimative value, the power maximum power point is accurately estimated by the strong tracking Unscented Kalman filer, and its corresponding control voltage is obtained. The MPPT tracking accuracy is improved on the basis of assuring the MPPT tracking speed. The mutation status of power is detected by tracking the state, and the MPPT misjudgment problem is avoided. The correctness and effectiveness of the strategy is verified by simulation and experiment.


Zhang R.,Nanchang University
Journal of Convergence Information Technology | Year: 2011

In this paper, we aim at solving job shop scheduling problems with the total weighted tardiness objective. In order to save computational time, several effective dispatching rules are adopted for constructing feasible schedules. Meanwhile, it is noticeable that the rule selections for each machine are not mutually independent but actually interrelated. Under such circumstances, an estimation of distribution algorithm (EDA) is proposed to optimize the combination of the rules. The superiority of this approach is verified by extensive computational experiments and comparisons.


Xing X.,University of Guelph | Cui S.W.,Agriculture and Agri Food Canada | Nie S.,Nanchang University | Phillips G.O.,Glyndwr University | And 2 more authors.
Carbohydrate polymers | Year: 2015

Main objective of this study was to investigate the detailed structural information about O-acetylated sugar residues in Dendronan(®). A water solution (2%, w/w) of Dendronan(®) was treated with endo-β-mannanase to produce oligosaccharides rich in O-acetylated sugar residues. The oligosaccharides were partly recovered by ethanol precipitation (70%, w/w). The recovered sample (designated Hydrolyzed Dendrobium officinale Polysaccharide, HDOP) had a yield of 24.7% based on the dry weight of Dendronan(®) and was highly O-acetylated. A D2O solution of HDOP (6%, w/w) generated strong signals in (1)H, (13)C, 2D (1)H-(1)H COSY, 2D (1)H-(1)H TOCSY, 2D (1)H-(1)H NOESY, 2D (1)H-(13)C HMQC, and 2D (1)H-(13)C HMBC NMR spectra. Results of NMR analyses showed that the majority of O-acetylated mannoses were mono-substituted with acetyl groups at O-2 or O-3 position. There were small amounts of mannose residues with di-O-acetyl substitution at both O-2 and O-3 positions. Minor levels of mannoses with 6-O-acetyl, 2,6-di-O-acetyl, and 3,6-di-O-acetyl substitutions were also identified. Much information about sugar residue sequence was extracted from 2D (1)H-(13)C HMBC and 2D (1)H-(1)H NOESY spectra. (1)J(C-H) coupling constants of major sugar residues were obtained. Evidences for the existence of branches or O-acetylated glucoses in HDOP were not found. The major structure of Dendronan(®) is shown as follows: [Formula: see text] M: β-D-mannopyranose; G: β-D-glucopyranose; a: O-acetyl group. Crown Copyright © 2014. Published by Elsevier Ltd. All rights reserved.


Shao Q.,Nanchang University | Shao Q.,University of Arkansas for Medical Sciences | Kannan A.,University of Arkansas for Medical Sciences | Lin Z.,Huazhong University of Science and Technology | And 3 more authors.
Cancer Research | Year: 2014

Merkel cell carcinoma (MCC) is an aggressive neuroendocrine tumor of the skin currently with no cure. In this study, we have first demonstrated that c-Myc overexpression is common in MCC. By targeting c-Myc, bromodomain inhibitors have demonstrated antitumor efficacy in several preclinical human cancer models. Thus, we interrogated the role of c-Myc inhibition in MCC with c-Myc amplification by using the BET inhibitor JQ1. We have uncovered that c-Myc can be regulated by JQ1 in MCC cells with pathologic c-Myc activation. Moreover, JQ1 potently abrogates c-Myc expression in MCC cells and causes marked G1 cell-cycle arrest. Mechanistically, JQ1-induced cell-cycle arrest coincides with downregulation of cyclin D1 and upregulation of p21, p27, and p57, whereas JQ1 exerts no effect on apoptosis in MCC cells. Further knockdown of p21, p27, or p57 by shRNA partially protects cells from JQ1-induced cell-cycle arrest. In addition, c-Myc knockdown by shRNA generates significant cell-cycle arrest, suggesting that c-Myc overexpression plays a role in MCC pathogenesis. Most importantly, JQ1 significantly attenuates tumor growth in xenograft MCC mouse models. Our results provide initial evidence, indicating the potential clinical utility of BET protein inhibitors in the treatment of MCC with pathologic activation of c-Myc. ©2014 AACR.


Two separate wavelength 1315 nm and 1550 nm were most widely used in near-infrared spectrum region. Based on a four-layer structure and a symmetry structure, a initial thin film stack system was constructed. Then it was optimized alternately by simplex and conjugate graduate algorithm, a beam splitter with splitting ratio R:T = 50:50 at this two wavelength was gained. The design result showed that the difference between reflectivity of P and S light around wavlength range 1300-1330 nm and 1535-1565 nm at incident angle 40 -50 was all below 2%. That indicated our design controlled the polarization deviation well at two separate wavelength with a reasonable range for both wavelength and incident angle. © 2012 Elsevier GmbH.


Li C.,Nanchang University
Applied Mechanics and Materials | Year: 2014

The paper design a new employment website, which change the previous employment website focusing only on employment information release mode, pay attention to improve students' employment ability, establish several enterprises and graduates, entrepreneurship and other. At the same time with JSP engine, Oracle established the information interactive website as the background database server; it will improve the efficiency and quality of the traditional employment information. At the same time, the paper introduces implementation of enterprise SMS platform using a GSM module, including the hardware environment, the SMS server software architecture, function and design. The scheme realizes the information exchange between students, teachers, and parents, through the practical operation, proved that the system has good practicability, solves many problems that exist in the employment information service, it has less demanding on the hardware, the realization of a simple, two times the development of convenient features. © (2014) Trans Tech Publications, Switzerland.


Based on mathematical model of multiobjective optimization and a novel constrained nonlinear multiobjective optimization immune algorithm, two nonpolarizing antireflection coating working at broadband and double waveband spectrum range respectively are designed in this paper. The results show that the spectrum curve of s-polarization part and p-polarization part are all very little. Which can satisfy the actual requirement very good. © 2012 Elsevier GmbH.


Li A.,Nanchang University
Chinese Journal of Sensors and Actuators | Year: 2011

It is necessary to equip TPMS on a vehicle like a van or a bus to reduce the risk of accidents that are caused by under inflated tires, however, TPMS sensor chips with maximum pressure over 800kPa are very expensive. This paper discusses the development of a novel design of TPMS wireless sensor nodes based on TI processor MSP430F2112, including the system architecture, hardware, software control strategy and the nonlinear compensation algorithm of the pressure sensor. The test results show that the temperature compensation approach of the pressure sensor is simple and effective. The proposed scheme of TPMS sensor nodes possesses the advantages of reliable communication, flexible configuration, small size, light weight, low power consumption and cost, and wide application prospect.


Qi X.-G.,Shandong University | Yang L.-Z.,Shandong University | Liu K.,Nanchang University
Computers and Mathematics with Applications | Year: 2010

In this paper, we investigate the uniqueness problems of difference polynomials of meromorphic functions that share a value or a fixed point. We also obtain several results concerning the shifts of meromorphic functions and the sufficient conditions for periodicity which improve some recent results in Heittokangas et al. (2009) [10] and Liu (2009) [11]. © 2010 Elsevier Ltd. All rights reserved.


Jiang D.-Y.,Nanchang University
International Journal of Theoretical Physics | Year: 2016

We investigate entanglement inseparability and bipartite entanglement of in two-component Bose-Einstein condensate in the presence of the nonlinear interatomic interaction, interspecies interaction. Entanglement inseparability and bipartite entanglement have the similar properties. More entanglement can be generated by adjusting the nonlinear interatomic interaction and control the time interval of the entanglement by adjusting interspecies interaction. © 2016 Springer Science+Business Media New York


Lv X.L.,Nanchang University
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials | Year: 2012

To study the chemical constituents of the roots of Vaccinium bracteatum. The constituents were separated and purified with chromatographic methods (including silica gel, Sephadex LH-20 and RP-18 column chromatography), and their structures were determined by spectroscopic methods (including MS, 1H-NMR and 13C-NMR). 10 compounds were isolated from the roots of Vaccinium bracteatu and were elucidated as chlorogenic acid (1), pinoresinol (2), ferulic acid (3), kaempferol (4), trans-caffeic acid (5), beta-sitosterol (6), quercetin (7), oleanolic acid (8), apigenin (9) and luteolin (10). Compounds 1 -3 are obtained from this plant for the first time.


Peng D.,Nanchang University | Zhang X.,Nanjing Southeast University
Energy | Year: 2016

A regenerator is one of the main components of a solar liquid desiccant cooling system. The regenerator used in this application is a forced counter flow type solar collector/regenerator(C/R). Experimental results of the tests indicate that there occurs a maximum value for regeneration efficiency at some air flow-rate. The regeneration efficiency of solution at ambient temperature decreases with the increase in solution flow-rate, instead of increasing at moderate temperature. The inlet temperature of solution has great influence on the regeneration efficiency and a higher concentration of solution is accompanied by a lower efficiency of regeneration. Compared with the regeneration efficiency at Ya,in = 20 g/kg, the regeneration efficiency was increased by about 40% at Ya,in = 10 g/kg. Higher solar radiation intensity will better regeneration performance of the C/R. Air flow-rate has far more effect on heat and mass coefficients between air and solution than solution flow-rate. The solution inlet temperature and salt concentration have contrary effects on heat and mass transfer coefficients with increase in their values. By Simpson numerical integration, two correlations on heat and mass transfer characteristics were given. Finally, it was concluded that the proposed solar collector/regenerator performs satisfactorily in humid climates of the Southern China. © 2016 Elsevier Ltd


Wang Z.,Zhejiang University | Shen L.,Nanchang University | Yu Z.,Zhejiang University | Zhang X.,Zhejiang University | Zheng X.,Zhejiang University
Journal of the Optical Society of America B: Optical Physics | Year: 2013

Magneto-optical and regular photonic crystals with triangular lattice are designed to construct one-way waveguides. Accordingly, two types of efficient beam splitters with one-way input channels are proposed and investigated. One of the proposed beam splitters is a 1 × 2 splitter, which achieves 50/50 splitting based on the structural symmetry. Since both output channels are one-way waveguides, this splitter is immune to interferences at the output ends. The other is a 1 × 3 beam splitter, in which one output channel is a regular waveguide and the others are one-way waveguides. It is shown that the 1 × 3 splitter can provide equal splitting ratios in the guiding band if defects with proper parameters are introduced in the splitting region. © 2012 Optical Society of America.


Man C.-S.,University of Kentucky | Huang M.,Nanchang University
Journal of Elasticity | Year: 2011

The Voigt-Reuss-Hill (VRH) average provides a simple way to estimate the elastic constants of a textured polycrystal in terms of its crystallographic texture and the elastic constants of the constituting crystallites. Empirically the VRH estimates were found in most cases to have an accuracy comparable to those obtained by more sophisticated techniques such as self-consistent schemes. In this paper we determine, in the space of fourth-order tensors with major and minor symmetries, a special set of irreducible basis tensors, with which we obtain a simple explicit formula for the VRH average for elastic polycrystals with arbitrary crystal and texture symmetries. Our formula is correct to first order in the texture coefficients. © The Author(s) 2011.


Ni W.,Nanchang University | Cheng D.,Chinese Academy of Sciences
Journal of Systems Science and Complexity | Year: 2012

The stabilization of switched linear systems with constrained inputs (SLSCI) is considered. The authors design admissible linear state feedbacks and the switching rule which has a minimal dwell time (MDT) to stabilized the system. First, for each subsystem with constrained inputs, a stabilizing linear state feedback and an invariant set of the closed-loop system are simultaneously constructed, such that the input constraints are satisfied if and only if the closed-loop system's states lie inside this set. Then, by constructing a quadratic Lyapunov function for each closed-loop subsystem, an MDT is deduced and an MDT-based switching strategy is presented to ensure the stability of the switched system. © 2012 Institute of Systems Science, Academy of Mathematics and Systems Science, CAS and Springer-Verlag Berlin Heidelberg.


Deng X.-F.,Nanchang University
Publications of the Astronomical Society of Japan | Year: 2014

In this work, the apparent-magnitude limited Main galaxy sample of the Sloan Digital Sky Survey Data Release 8 (SDSS DR8) is applied to examine the correlation between u-band luminosity and environment at fixed parameters or for different galaxy families. Statistical results show that the abnormal environmental dependence of u-band luminosity for late-type galaxies and Low Stellar Mass (LSM) galaxies is fairly strong in the redshift range 0.03 ≤ z ≤ 0.09, while that for early-type galaxies, High Stellar Mass (HSM) galaxies, red galaxies, and blue galaxies is very weak in nearly all redshift bins. The result of this study further demonstrates that color is indeed fundamental in correlations between galaxy properties and the environment and that much of the u-band luminosity-density relation is likely due to the relation between color and density. © The Author 2014. Published by Oxford University Press on behalf of the Astronomical Society of Japan. All rights reserved.


Deng X.-F.,Nanchang University
Research in Astronomy and Astrophysics | Year: 2014

Using the LOWZ and CMASS samples of the ninth data release (DR9) from the SDSS-III Baryon Oscillation Spectroscopic Survey (BOSS), I investigate properties of star forming galaxies and active galactic nuclei (AGNs). The CMASS sample seriously suffers from the radial selection effect, even within the redshift 0.44 ≤ z ≤ 0.6, which will likely lead to statistical conclusions in the CMASS sample being less robust. In the LOWZ sample, the fraction of star-forming galaxies is nearly constant from the least dense regime to the densest regime; the AGN fraction is also insensitive to the local environment. In addition, I note that in the LOWZ sample, the distributions of stellar mass and stellar velocity dispersion for star forming galaxies and AGNs are nearly the same. © 2014 National Astronomical Observatories of Chinese Academy of Sciences and IOP Publishing Ltd.


Deng X.-F.,Nanchang University
Research in Astronomy and Astrophysics | Year: 2014

I investigate the environmental dependence of galaxy colors in the CMASS sample of the Sloan Digital Sky Survey Data Release 9 (SDSS DR9). To decrease the radial selection effect, I divide the CMASS sample into subsamples with a redshift binning size of Δz = 0.01 and analyze the environmental dependence of the u - r, u - g, g - r, r - i and i - z colors for these subsamples in each redshift bin. Statistical analysis shows that all five colors weakly correlate with the local environment, which may mean that the environmental processes responsible for a galaxy's properties proceed slowly over cosmic time. © 2014 National Astronomical Observatories of Chinese Academy of Sciences and IOP Publishing Ltd.


Liu W.,University of Kentucky | Li Y.,University of Kentucky | Li Y.,Nanchang University | Cai Y.,University of Kentucky | Sekulic D.P.,University of Kentucky
Langmuir | Year: 2011

The location of the triple line as a function of time has been recorded for a series of organic liquids, with various surface tension to viscosity ratios, wicking upward a rough Cu6Sn5/Cu intermetallic (IMC) substrate. The complex topographical features of such an IMC rough surface are characterized by surface porosity and surface roughness. A theoretical model for wicking upward a rough surface has been established by treating the rough IMC surface as a two-dimensional porous medium featuring a network of open microtriangular grooves. The model is verified against experimental data. The study confirms that the kinetics of capillary rise of organic liquids in a nonreactive flow regime over a porous surface having arbitrary but uniformly distributed topographical features involves (i) surface topography metrics (i.e., permeability, tortuosity/porosity, and geometry of the microchannel cross section); (ii) wicking features (i.e., contact angle and filling factor); and (iii) physical properties of liquids (i.e., surface tension and viscosity). An excellent agreement between theoretical predictions and experimentally obtained data proves, for a selected filling factor η, validity of the analytically established model. Scaled data sets show that, for a given rough surface topography, (i) wicking kinetics of considered liquids depend on properties of liquids, that is, surface tension to viscosity ratios and contact angles; (ii) the filling factor for all tested liquids is an invariant, offering good prediction within the range of ∼0.9-1.0. The distance of the wicking front versus square root of time relationship was well established throughout the whole considered wicking evolution time. © 2011 American Chemical Society.


Effects of Nd addition on microstructure and mechanical properties of ZL101 aluminum alloys were investigated by optical microscope, scanning electron microscope, universal testing machine and differential thermal analyzer. The results show that when ZL101 alloys were modified with Nd, coarse α-Al phases changed into fine grains and eutectic Si transformed from acicular and lath-like into fibrous one. Nd-rich intermetallic compound with submicron size was found in the modified alloy. When Nd content reached to 0.5 wt.%, the optimized mechanical properly of the modified alloys was obtained, with a maximal ultimate tensile strength (178 MPa) and elongation (5.6%). Fracture morphology of modified alloys changed from a mixture of ductile and cleavage fracture into ductile fracture. Compare to eutectic transformation temperature of the unmodified alloy, eutectic transformation temperature of the 0.5 wt.% Nd modified alloy increases 2.8℃, resulting in increasing of ZL101 alloy undercooling degree. ©, 2015, Chinese Mechanical Engineering Society. All right reserved.


Peng X.,Nanchang University
Journal of molecular and cellular cardiology | Year: 2013

FAT10 is a new member of the ubiquitin-like protein family with yet-to-be defined biological functions in the heart. Our objective was to determine the role of FAT10 in the heart. FAT10 is expressed in the normal human and murine hearts, as detected by qPCR and Western blotting. Expression of FAT10 is increased in the heart at the border zone of myocardial infarction and in cultured neonatal rat cardiac myocytes (NRCM) subjected to hypoxia/reoxygenation (H/R) stress. Lentiviral-mediated overexpression of FAT10 in NRCM reduced p53 (TP53) and its target miR-34a levels, while BCL2 level, a target of miR-34a, was increased and BAX level, a pro-apoptotic protein, was reduced. These changes were associated with reduced apoptosis, detected by FACS analysis of annexin-V expression and TUNEL assay, in response to H/R injury. Knock down of FAT10 by shRNA targeting had the opposite effects. Likewise, lentiviral mediated expression of miR-34a was associated with reduced BCL2 and increased BAX levels in NRCM and also reversed changes in BCL-2 and BAX levels observed upon over-expression of FAT10. Treatment of NRCM with proteasome inhibitor MG132 increased p53 and miR-34a levels and reduced BLC2/BAX ratio. These changes were not reversed upon over-expression of FAT10. Thus, FAT10 is upregulated in the heart and NRCM in response to H/R stress, which protects cardiac myocytes against apoptosis. The anti-apoptotic effects of FAT10 are associated with suppression of p53, probably through fatylation and proteasomal degradation, reduced miR-34a expression, and a shift in the BCL2/BAX proteins against apoptosis. Thus, FAT10 is a cardioprotective protein. Copyright © 2013 Elsevier Ltd. All rights reserved.


Abdi J.,University Utrecht | Chen G.,Nanchang University | Chang H.,Toronto General Research Institute | Chang H.,University of Toronto | Chang H.,A+ Network
Oncotarget | Year: 2013

In the era of new and mostly effective therapeutic protocols, multiple myeloma still tends to be a hard-to-treat hematologic cancer. This hallmark of the disease is in fact a sequel to drug resistant phenotypes persisting initially or emerging in the course of treatment. Furthermore, the heterogeneous nature of multiple myeloma makes treating patients with the same drug challenging because finding a drugable oncogenic process common to all patients is not yet feasible, while our current knowledge of genetic/epigenetic basis of multiple myeloma pathogenesis is outstanding. Nonetheless, bone marrow microenvironment components are well known as playing critical roles in myeloma tumor cell survival and environment-mediated drug resistance happening most possibly in all myeloma patients. Generally speaking, however; real mechanisms underlying drug resistance in multiple myeloma are not completely understood. The present review will discuss the latest findings and concepts in this regard. It reviews the association of important chromosomal translocations, oncogenes (e.g. TP53) mutations and deranged signaling pathways (e.g. NFκB) with drug response in clinical and experimental investigations. It will also highlight how bone marrow microenvironment signals (Wnt, Notch) and myeloma cancer stem cells could contribute to drug resistance in multiple myeloma.


A batch-to-batch model-based iterative learning control (ILC) strategy for the end-point product quality control in batch processes is proposed in this paper. A nonlinear model for end-point product quality is developed from process operating data using kernel principal component regression (KPCR). The ILC algorithm is derived to calculate the control policy by linearizing the KPCR model around the nominal trajectories and minimising a quadratic objective function concerning the end-point product quality. To overcome the detrimental effects of unknown process variations or disturbances, it is proposed in the paper that the KPCR model should be updated in a batchwise manner by removing the earliest batch data from the training data set and adding the latest batch data to the training data set. The ILC based on updated KPCR model shows adaptability for process variations or disturbances when applied to a simulated batch polymerization process. Comparisons between KPCR model and principal component regression (PCR) model based ILCs are also made in the simulations. © 2013 ACADEMY PUBLISHER.


Liu Y.,Nantong University | Liu S.Q.,Nanchang University | Dai B.,Nantong University
Physics of Plasmas | Year: 2011

Arbitrary amplitude solitary kinetic Alfvén waves (KAWs) in a plasma with q-nonextensive electrons are investigated by the conventional Sagdeev pseudopotential method, through which the existence of solitary KAWs is analyzed theoretically and numerically. It is shown only solitons with density hump can exist, the amplitude of which depends sensitively on the parameter q and the plasma β. There is an upper limit for the amplitude of solitary wave which decreases with the increase of q and β. The results obtained in the framework of Maxwellian distribution are reproduced when q → 1. © 2011 American Institute of Physics.


Long C.,Nanchang University
Advances in Information Sciences and Service Sciences | Year: 2012

The problem of evaluating the garden plant landscape with linguistic information is the multiple attribute decision making (MADM) problems. In this paper, we solve the multiple attribute decision making (MADM) problems for evaluating the garden plant landscape with linguistic information. Then we utilize the linguistic weighted arithmetic average (LWAA) operator to aggregate the linguistic variables corresponding to each alternative, and then rank the alternatives by means of the aggregated linguistic information. Finally, an illustrative example for garden plant landscape evaluation is given to verify the developed approach and to demonstrate its practicality and effectiveness.


Zhang Z.,Nanchang University
Journal of Mechanical Science and Technology | Year: 2010

Even structurally simple manufacturing systems can be operationally complex. This operational complexity can be colloquially defined as the uncertainty associated with managing the dynamic variations, in time or quantity, across information and material flows at the manufacturing systems interface. This paper proposes a means of measuring the information demands placed on cellular manufacturing systems, as a result of this uncertainty. A utility function for complexity is proposed according to the relationships between the complexity and utility in a manufacturing system and the underlying trend that the system becomes more and more complex in an everchanging environment is analyzed. This paper mathematically models the static entropy and the dynamic entropy of cellular manufacturing systems from an information-theoretic perspective. A unique feature of this measure is that it captures, in relative terms, the expected amount of information required to describe the state of the system. The measure provides flexibility in the scope and detail of analysis. Finally, an example is used to demonstrate the validity of the proposed methodology. © 2010 The Korean Society of Mechanical Engineers and Springer-Verlag Berlin Heidelberg.


Wan J.,Nanchang University
Zhonghua wei zhong bing ji jiu yi xue | Year: 2014

To report the treatment process of the first case of human pneumonia resulted from H10N8 avian influenza virus infection in the world for providing the data for clinical diagnosis and treatment. On November 30, 2013, the first case of human infection with H10N8 avian influenza virus was discovered in Nanchang City, Jiangxi Province. Its clinical symptoms and epidemiology were analyzed and compared with the characteristics of human infection with H7N9 avian influenza virus. A 73-year old female patient complaining of cough and chest tightness for 3 days and fever for 1 day was admitted to the Department of Respiratory Diseases of the Third Affiliated Hospital of Nanchang University on November 30, 2013. As the illness became worse, the patient was transferred into Intensive Care Unit (ICU) of the Department of Critical Care Medicine on December 2. The patient's condition deteriorated, manifesting multiple organ failure (MOF) on December 5. At 08:30 on December 6, cardiac arrest occurred, and the patient died after inefficient resuscitation. (1) Epidemiological investigation: the patient was an elderly woman, suffering from a variety of chronic diseases (hypertension, coronary heart disease, myasthenia gravis, etc) and impaired immune function (undergone thymectomy), all of them were predisposing factors for deterioration of her health. She had visited the live poultry market one week before admission, and developed symptoms of influenza. The transmission route was the respiratory tract, which was similar to H7N9 avian influenza. (2) CLINICAL MANIFESTATIONS: the patient had flu-like symptoms, such as cough and fever (39.1 centigrade), but no headache or myalgia. Two days later pneumonia accompanied with respiratory distress developed and a large amount of bloody sputum was sucked out through tracheostomy tube (2 000 mL/24 h). Acute kidney injury, acute respiratory distress syndrome (ARDS), septic shock, and unconsciousness occurred, all of which was consistent with the diagnosis of H7N9 avian influenza. (3) Auxiliary examination: with the exception of a decrease in lymphocyte ratio (0.070), aspartate aminotransferase (AST) was slightly increased (57 U/L), C- reactive protein (CRP) was elevated (>200 mg/L), but the platelet count, creatine kinase, lactate dehydrogenase, alanine aminotransferase and myoglobin were not increased, while leucocyte count was increased slightly (10.34×10(9)/L). The changes in above indexes did not match the characteristics of H7N9 avian influenza. However, the aggravated consolidation of the lung conformed to that of H7N9 avian influenza. (4) DIAGNOSIS AND TREATMENT: according to the clinical manifestations, aggravation of consolidation of the lung, and epidemiological evidence, the diagnosis of avian influenza was considered. Though therapeutic dose of oseltamivir was given as antiviral treatment for the early therapy, and other therapeutic measures such as energetic respiratory and circulatory support, and immunosuppressant therapy were given, the patient eventually died from respiratory failure and shock. (5) The Chinese disease prevention and control center (CDC) confirmed that, the patient was infected H10N8 avian influenza virus. No person with close contact with the patient was infected, as screened by Nanchang City and Chinese CDC. Human infection with H10N8 avian influenza was not exactly the same as that of H7N9. It was difficult to get true information from the conventional laboratory examinations, while the clinical characteristic and epidemiology were essential for the diagnosis. Referring to the treatment regime for human infection with H7N9 avian influenza virus, therapeutic dose of neuraminidase inhibitors could not reverse deterioration of pulmonary pathology. Chinese CDC found that the risk of human infection and transmission of H10N8 avian influenza virus through personal contact was low.


Zhang R.,Nanchang University | Song S.,Tsinghua University | Wu C.,Tsinghua University
Applied Soft Computing Journal | Year: 2013

In real-world manufacturing systems, the processing of jobs is frequently affected by various unpredictable events. However, compared with the extensive research for the deterministic model, study on the random factors in job shop scheduling has not received sufficient attention. In this paper, we propose a hybrid differential evolution (DE) algorithm for the job shop scheduling problem with random processing times under the objective of minimizing the expected total tardiness (a measure for service quality). First, we propose a performance estimate for roughly comparing the quality of candidate solutions. Then, a parameter perturbation algorithm is applied as a local search module for accelerating the convergence of DE. Finally, the K-armed bandit model is utilized for reducing the computational burden in the exact evaluation of solutions based on simulation. The computational results on different-scale test problems validate the effectiveness and efficiency of the proposed approach. © 2012 Elsevier B.V. All rights reserved.


The present study aimed to investigate the effect of adenovirus-mediated urokinase-type plasminogen activator (uPA) transduction on uPA expression and fibrinolytic activity in human umbilical vein endothelial cells (HUVECs). Recombinant adenovirus vectors containing the human uPA gene were constructed and transduced into HUVECs. The expression and fibrinolytic activity of uPA was then assessed in HUVECs using western blot analysis, ELISA and colorimetric assay. The experiments were performed in three groups: The ad/uPa (n=3), ad/neg control (n=3) and blank control (n=3) groups. Western blot analysis revealed that uPA protein expression in the HUVECs in the ad/uPa group was significantly increased compared with those in the ad/neg control or blank groups (P<0.01). The uPA protein levels in the supernatant of the three groups were 379.40±2.46, 240.01±1.16 and 256.10±3.04 ng/l, respectively, showing that the uPA protein levels were significantly higher in the supernatant in the ad/uPa group compared with those in the ad/neg control or blank groups. uPA activity was determined using a colorimetric method and was found to be 40238.49±5755 IU/mg in the HUVECs in the ad/uPa group, which was significantly higher than that in the HUVECs in the ad/neg control (6180.03±942.38 IU/mg) or blank groups (3346.06±928.81 IU/mg) (both P<0.01). These findings suggested that transduction of the uPA gene increased uPA protein expression and fibrinolytic activity in HUVECs.


Hu B.,Nanchang University
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2014

In this paper, we study residual symmetries in the lepton sector. Our first concern is the symmetry of the charged lepton mass matrix in the basis where the Majorana neutrino mass matrix is diagonal, which is strongly constrained by the requirement that the symmetry group generated by residual symmetries is finite. In a recent work, R.M. Fonseca and W. Grimus found that there exists a set of constraint equations that can be completely solved, which is essential in their approach to the classification of lepton mixing matrices that are fully determined by residual symmetries. In this paper, a method to handle trigonometric Diophantine equations is introduced. We will show that the constraint equations found by Fonseca and Grimus can also be solved by this method. Detailed derivation and discussion will be presented in a self-contained way. In addition, we will also show that, in the case where residual symmetries satisfy a reality condition, this method can be used to solve the equation constraining parameters in the symmetry assignment that controls the group structure generated by residual symmetries and is directly related to mixing matrix elements. © 2014 American Physical Society.


PKZ (PKR-like) was discovered as a member of elF2α kinase family in fish, which possesses a conserved catalytic domain of an eIF2α kinase in C-terminal and also two Z-DNA-binding domains (Zα1 and Zα2) in N-terminal. PKZ can be activated through binding of Zα to Z-DNA. However, the regulatory function of PKZ Zα still remains unclear. To investigate a molecular mechanism of how PKZ Zα interacts with Z-DNA, we expressed Zα polypeptide Zα1α2 in Escherichia coli Rosetta strain and purified by affinity chromatography on Ni-NTA resin. Different lengths of oligonucleotide DNAs with various inserts, namely d(GC)(n) (n = 6, 8, 10, 13), d(TA)(n) (n = 6, 10), non-d(GC), and non-d(TA), were designed and synthesized. Circular dichroism spectrum and gel mobility shift assays were used to investigate the effects of Zα1α2 on the conformational transition of different oligonucleotide DNAs. Results showed that oligonucleotide DNAs retained a conventional B-DNA conformation in the absence of Zα1α2. With the increasing amount of Zα1α2 titration, d(GC)(n) were recognized and converted to Z-DNA conformation to some degree. With increasing the repeat number (from n = 6 to n = 13), the tendency of conformational transition became more obvious. However, the conformation of oligonucleotides with d(TA)(n) inserts changed a little in the presence of Zα1α2, and Zα1α2 had no effect on conformational transition of oligonucleotides with non-d(GC) or non-d(TA) inserts. Gel mobility shift assays further showed that Zα1α2 could bind to oligonucleotide with d(GC)(10). In other words, Zα1α2 can turn oligonucleotides with d(GC)(n) inserts into Z-DNA conformation and bind to it with high affinity.


Huang G.,Nanchang University
Wei sheng wu xue bao = Acta microbiologica Sinica | Year: 2011

We investigated the proteomic profile of Lactobacillus brevis NCL912 under optimum pH and acidic pH in the media without the addition of sodium L- glutamate to characterize the differential expression proteins and function by two-dimensional gel electrophoresis. The differential expression proteins were separated and analyzed by two-dimensional gel electrophoresis, mass spectrum and bioinformatics. The results showed that the two-dimensional gel electrophoresis profiles of L. brevis NCL912 were uniformity, well-resolution and repeatability. 25 proteins were differently expressed in the two profiles. Among them, 8 proteins were identified and analyzed by the mass spectrum and bioinformatics due to the lack of genome sequence data of L. brevis NCL912. These proteins played the roles of the synthesis of protein and DNA, glycolysis and regulating the cellular energy level. The differential expression proteins might play the important role in the acid stress resistance mechanism which may protect cell against acid stress.


Peng W.,Nanchang University | Criscione C.D.,Texas A&M University
Infection, Genetics and Evolution | Year: 2012

Ascaris is a large parasitic roundworm (nematode) of the small intestine of humans and pigs. These roundworms cause the socioeconomically important disease, ascariasis. For the past 20 years, molecular markers have been used in studies on Ascaris and ascariasis, and added valuable information to the understanding of these roundworms. Here, we provide a review of these studies on human and pig roundworms. We begin with a summary of studies using molecular phenotypic markers to compare Ascaris from humans and pigs, followed by a synopsis of comparisons using genetic markers. We then draw forth inferences in the aspects of host affiliation and infection success, transmission between and among humans and pigs, evolutionary history of Ascaris. We also highlight additional topics such as mating dynamics, diagnostics, and paleoparasitology where molecular epidemiological approaches have been utilized. © 2012 Elsevier B.V.


Li L.-X.,Nanchang University
Advances in Information Sciences and Service Sciences | Year: 2012

In this paper, through using the basic principle of symbiotic theory, we analyzed the symbiotic behavior-choice of enterprise network. We considered the enterprises networking-process is a process to choice the enterprise symbiotic object, these enterprises will form a symbiotic network through their some resources complementary. We believed that the choice of corporate symbiotic object include the choice principle in incomplete information and the choice principle in complete information. Under the incomplete information, these enterprises will choice the object through the symbiotic energy, under the complete information, these enterprises will choice the object through the proximity rule and the correlation degree rule, thus, we must ensure the validity of the symbiotic corporate network relationship.


Xu S.,Nanchang University
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi | Year: 2010

Biological tissues generally exhibit nonlinearity, anisotropy, quasi-incompressibility and viscoelasticity about material properties. Simulating the behaviour of elastic objects in real time is one of the current objectives of virtual surgery simulation which is still a challenge for researchers to accurately depict the behaviour of human tissues. In this paper, we present a classification of the different deformable models that have been developed. We present the advantages and disadvantages of each one. Finally, we make a comparison of deformable models and perform an evaluation of the state of the art and the future of deformable models.


Zuo W.,Tsinghua University | Huang F.,Tsinghua University | Chiang Y.J.,U.S. National Institutes of Health | Li M.,Chinese PLA General Hospital | And 11 more authors.
Molecular Cell | Year: 2013

Transforming growth factor β (TGF-β) is a potent antiproliferative factor in multiple types of cells. Deregulation of TGF-β signaling is associated with the development of many cancers, including leukemia, though the molecular mechanisms are largely unclear. Here, we show that Casitas B-lineage lymphoma (c-Cbl), a known proto-oncogene encoding an ubiquitin E3 ligase, promotes TGF-β signaling by neddylating and stabilizing the type II receptor (TβRII). Knockout of c-Cbl decreases the TβRII protein level and desensitizes hematopoietic stem or progenitor cells to TGF-β stimulation, while c-Cbl overexpression stabilizes TβRII and sensitizes leukemia cells to TGF-β. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TβRII at Lys556 and Lys567. Neddylation of TβRII promotes its endocytosis to EEA1-positive early endosomes while preventing its endocytosis to caveolin-positive compartments, therefore inhibiting TβRII ubiquitination and degradation. We have also identified a neddylation-activity-defective c-Cbl mutation from leukemia patients, implying a link between aberrant TβRII neddylation and leukemia development. © 2013 Elsevier Inc.


Liu X.R.,Nanchang University
The British journal of nutrition | Year: 2013

Industry-generated trans-fatty acids (TFA) are detrimental to risk of CHD, but ruminant-originated TFA have been reported as neutral or equivocal. Therefore, the total TFA amount should not be the only factor considered when measuring the effects of TFA. In the present study, we addressed whether a version of the TFA index that unifies the effects of different TFA isomers into one equation could be used to reflect CHD risk probability (RP). The present cross-sectional study involved 2713 individuals divided into four groups that represented different pathological severities and potential risks of CHD: acute coronary syndrome (ACS, n 581); chronic coronary artery disease (CCAD, n 631); high-risk population (HRP, n 659); healthy volunteers (HV, n 842). A 10-year CHD RP was calculated. Meanwhile, the equation of the TFA index was derived using five TFA isomers (trans-16 : 1n-7, trans-16 : 1n-9, trans-18 : 1n-7, trans-18 : 1n-9 and trans-18 : 2n-6n-9), which were detected in the whole blood, serum and erythrocyte membranes of each subject. The TFA index and the 10-year CHD RP were compared by linear models. It was shown that only in the erythrocyte membrane, the TFA isomers were significantly different between the groups. In the ACS group, industry-generated TFA (trans-16 : 1n-9, trans-18 : 1n-9 and trans-18 : 2n-6n-9) were the highest, whereas ruminant-originated TFA (trans-16 : 1n-7 and trans-18 : 1n-7), which manifested an inverse relationship with CHD, were the lowest, and vice versa in the HV group. The TFA index decreased progressively from 7·12 to 5·06, 3·11 and 1·92 in the ACS, CCAD, HRP and HV groups, respectively. The erythrocyte membrane TFA index was positively associated with the 10-year CHD RP (R 2 0·9981) and manifested a strong linear correlation, which might reflect the true pathological severity of CHD.


Feng Y.,Nanchang University
Journal of Theoretical and Applied Information Technology | Year: 2012

Cluster analysis in data mining is an important research field; it has its own unique position in a large number of data analysis and processing. The research about Clustering makes a spurt development after more than 20 years, and then produced a variety of types and application of the clustering algorithm. Data Mining is one of the pop researches in information industry last few years. This paper analyses some typical methods of the cluster analysis and represent the application of the cluster analysis in Data Mining. © 2005 - 2012 JATIT & LLS. All rights reserved.


Fang Y.,Nanchang University
Science China: Physics, Mechanics and Astronomy | Year: 2014

The fundamental law for protein folding is the thermodynamic principle. The amino acid sequence of a protein determines its native structure and the native structure has the minimum Gibbs free energy. Lacking of a Gibbs free energy formula is the reason that all ab initio protein structure prediction only empirical and various empirical energy surfaces or landscapes are introduced to fill the gap. We make a quantum mechanics derivation of the Gibbs free energy formula G(X) using quantum statistics for a single conformation X. For simplicity, only monomeric self folding globular proteins are considered. © 2014 Science China Press and Springer-Verlag Berlin Heidelberg.


Yang M.,Capital Medical University | Liu J.,Capital Medical University | Shao J.,Nanchang University | Qin Y.,Capital Medical University | And 3 more authors.
Molecular Cancer | Year: 2014

Background: Tumor-associated macrophages (TAMs) are the major component of tumor-infiltrating leukocytes. TAMs are heterogeneous, with distinct phenotypes influenced by the microenvironment surrounding tumor tissues, but relatively little is known about the key molecular in these cells that contribute to malignant phenotypes. Autophagic activity is a critical factor in tumor development that contributes to enhancing cellular fitness and survival in the hostile tumor microenvironment. However, the molecular basis and relations between autophagy and TAMs polarization remain unclear.Methods: Cathepsin S (Cat S) expression was analyzed in human colon carcinoma and normal colon tissues. In vivo effects were evaluated using PancO2 subcutaneous tumor model and SL4 hepatic metastasis model. Immunofluorescence staining, flow cytometry and real-time PCR were done to examine TAMs polarization. Western blotting assay, transmission electron microscopy, mCherry-GFP-LC3 transfection and DQ-BSA degradation assays were carried out to determine its role in regulating autophagy.Results: In the present study, we showed that the enhanced expression of Cat S correlated with the severity of histologic grade as well as clinical stage, metastasis, and recurrence, which are known indicators of a relatively poor prognosis of human colon carcinoma. Cat S knockout led to decreased tumor growth and metastasis. Moreover, Cat S knockout inhibited M2 macrophage polarization during tumor development. We further demonstrated that Cat S was required for not only autophagic flux but also the fusion processes of autophagosomes and lysosomes in TAMs. Importantly, we found that Cat S contributed to tumor development by regulating the M2 phenotype of TAMs through the activation of autophagy.Conclusions: These results indicated that Cat S-mediated autophagic flux is an important mechanism for inducing M2-type polarization of TAMs, which leads to tumor development. These data provide strong evidence for a tumor-promoting role of autophagy in TAMs and suggest Cat S could be a potential target for cancer therapy. © 2014 Yang et al.; licensee BioMed Central Ltd.


Chen H.P.,Boston University | Chen H.P.,Nanchang University | Zhao Y.T.,Boston University | Zhao T.C.,Boston University
Critical Reviews in Oncogenesis | Year: 2015

In recent years it has become widely recognized that histone modification plays a pivotal role in controlling gene expression and is involved in a wide spectrum of disease regulation. Histone acetylation is a major modification that affects gene transcription and is controlled by histone acetyltransferases (HATs) and histone deacetylases (HDACs). HATs acetylate lysines of histone proteins, resulting in the relaxation of chromatin structure, and they also facilitate gene activation. Conversely, HDACs remove acetyl groups from hyperacetylated histones and suppress general gene transcription. In addition to histones, numerous nonhistone proteins can be acetylated and deacetylated, and they also are involved in the regulation of a wide range of diseases. To date there are 18 HDACs in mammals classified into 4 classes based on homology to yeast HDACs. Accumulating evidence has revealed that HDACs play crucial roles in a variety of biological processes including inflammation, cell proliferation, apoptosis, and carcinogenesis. In this review we summarize the current state of knowledge of HDACs in carcinogenesis and describe the involvement of HDACs in cancer-associated molecular processes. It is hoped than an understanding of the role of HDACs in cancer will lead to the design of more potent and specific drugs targeting selective HDAC proteins for the treatment of the disease. © 2015 by Begell House, Inc.


Hu G.,Shanghai Normal University | Huang S.,Nanchang University | Chen H.,Shanghai Normal University | Wang F.,Shanghai Normal University
Food Research International | Year: 2010

This paper demonstrates that rice bran hemicellulose A (RBHA), hemicellulose B (RBHB) and hemicellulose C (RBHC) have the potential for binding heavy metal ions. The quantity of metal ions bound varies from one rice bran fibre to another. As it can be inferred from the results of the study, RBHB was characterised by the highest capacity for metal ion (Pb, Cu and Cd) binding, followed by RBHC and RBHA. Binding of heavy metals to insoluble dietary fibre (RBDF) and cellulose from rice bran were found to be poor. Lignin from rice bran was the least active fraction for binding heavy metal ions. © 2009 Elsevier Ltd. All rights reserved.


Ling Y.,CAS Institute of High Energy Physics | Ling Y.,Nanchang University | Ling Y.,CAS Institute of Theoretical Physics | Niu C.,CAS Institute of High Energy Physics | And 3 more authors.
Physical Review Letters | Year: 2014

We construct a gravity dual for charge density waves (CDWs) in which the translational symmetry along one spatial direction is spontaneously broken. Our linear perturbation calculation on the gravity side produces the frequency dependence of the optical conductivity, which exhibits the two familiar features of CDWs, namely, the pinned collective mode and gapped single-particle excitation. These two features indicate that our gravity dual also provides a new mechanism to implement the metal to insulator phase transition by CDWs, which is further confirmed by the fact that dc conductivity decreases with the decreased temperature below the critical temperature. © 2014 American Physical Society.


Zhao C.,Tongji University | Deng H.,Tongji University | Li Y.,Tongji University | Liu Z.,Nanchang University
Journal of Hazardous Materials | Year: 2010

The photocatalysis degradation, mineralization and detoxification of oxytetracycline (OTC) in aqueous were investigated by 5A and 13X zeolite with nano-TiO2 loaded under UV light. The composite photocatalysts are characterized by X-ray diffraction (XRD) and field emission scanning (FESEM) technologies. The adsorption isotherms of OTC by 5A and 13X with different pH are evaluated. The results show that 654 and 1497 mg/g OTC of saturation adsorption capacity is reached by 5A and 13X at pH 7, respectively. Then the effect of TiO2 with 5A and 13X support and different wt% of TiO2 over the support on the resultant OTC removal, net photocatalytic degradation and influence factors such as TiO2 loading, initial pH, concentration of OTC and adding anion on degradation are investigated. The 15 wt% TiO2/5A and 10 wt% TiO2/13X photocatalysts are found optimum for OTC removal and degradation in aqueous. The mineralization was measured by total organic carbon (TOC) while combined toxicity change during OTC degradation was tested with standardized bioluminescence assay of inhibition rate on Vibrio qinghaiensis sp.-Q67 (Q67). The results suggest that TiO2/5A and TiO2/13X composite systems are effective photocatalysts for treatment of OTC in aqueous. © 2009 Elsevier B.V. All rights reserved.


Shu W.,Beijing Jiaotong University | Qian W.,Nanchang University | Qian W.,Beijing Key Laboratory of Knowledge Engineering for Materials Science
Knowledge-Based Systems | Year: 2014

Attribute measures, used to evaluate the quality of candidate attributes, play an important role in the process of attribute reduction. They largely affect the computational efficiency of attribute reduction. Existing attribute measures are acted on the whole universe in complete decision systems. There are few studies on improving attribute reduction algorithms from the perspective of attribute measures in incomplete decision systems, which motivates the study in this paper. This paper proposes new attribute measures that act on a dwindling universe to quicken the attribute reduction process. In particular, the monotonicity guarantees the rationality of the proposed attribute measures to evaluate the significance of candidate attributes. On this basis, the corresponding attribute reduction algorithms are developed in incomplete decision systems based on indiscernibility relation and discernibility relation, respectively. Finally, a series of comparative experiments are conducted with different UCI data sets to evaluate the performance of our proposed algorithms. The experimental results indicate that the proposed algorithms are efficient and feasible. © 2014 Elsevier B.V. All rights reserved.


Li S.-S.,Nanchang University
International Journal of Theoretical Physics | Year: 2014

I investigate the dependence of phase sensitivity on the initial input states. By adopting frozen-spin approximation, I first derive the analytical expresses of the angular momentum operators and then of quantum Fisher information, the phase sensitivity. It is shown that the initial input state with smaller value of angular momentum has the better degree of entanglement and phase sensitivity beats the Heisenberg limit. © 2014, Springer Science+Business Media New York.


Gong X.,Nanchang University
Acta Mathematica Scientia | Year: 2014

In this paper, we introduce a concept of quasi C-lower semicontinuity for set-valued mapping and provide a vector version of Ekeland's theorem related to set-valued vector equilibrium problems. As applications, we derive an existence theorem of weakly efficient solution for set-valued vector equilibrium problems without the assumption of convexity of the constraint set and the assumptions of convexity and monotonicity of the set-valued mapping. We also obtain an existence theorem of e{open}-approximate solution for set-valued vector equilibrium problems without the assumptions of compactness and convexity of the constraint set. © 2014 Wuhan Institute of Physics and Mathematics.


Hu G.-J.,Nanchang University | Hu X.-X.,Jiangxi Agricultural University
International Journal of Theoretical Physics | Year: 2014

We investigate spin squeezing and the mean quantum Fisher information per particle χ 2 for mixed Hamiltonian model. By adopting frozen-spin approximation, we first derive a analytical expression of spin squeezing parameter ξ 2 and then numerically calculate ξ 2 and χ 2. It is shown that most of the time the spin squeezing appears alternatively in the x and y directions, but it cannot appear simultaneously in the two directions. It is also shown that the smaller external field strength induces better entanglement and larger period. © 2013 Springer Science+Business Media New York.


Yang C.,Nanjing Medical University | Liu X.,Nanchang University | Li S.,Nanjing Medical University
Canadian Journal of Physiology and Pharmacology | Year: 2010

Our previous acute study on urocortin (Ucn) demonstrated that Ucn altered serum and tissue angiotensin-converting enzyme (ACE) activity in rats. Therefore, the present investigation was designed to explore the effect of long-term treatment with Ucn on somatic ACE (sACE) and other components of the renin-angiotensin system (RAS). After 8 weeks of intravenous administration of Ucn in spontaneously hypertensive rats (SHR), serum and tissue sACE, angiotensin II (Ang II), nitric oxide (NO), Ang-(1-7), and tissue chymase activities were evaluated. RT-PCR analysis was performed to determine the quantity of tissue sACE mRNA. Serum sACE activity was reduced by Ucn, although tissue sACE activity and tissue sACE mRNA were elevated. Chymase activity was observed to be enhanced by Ucn, whereas the ACE inhibitor enalapril failed to influence chymase. Serum and tissue Ang II activity was reduced, but NO and Ang-(1-7) production was increased in a concentration-dependent manner after Ucn treatment. Meanwhile, a significant decrease of the systolic blood pressure (SBP) was observed after the long-term Ucn administration, and there was a significant positive correlation (r 2 = 0.6993) between serum ACE activity and SBP. Pretreatment with the corticotropin-releasing factor (CRF) blocker astressin and the extracellular signal-regulated kinase 1/2 (ERK1/2) pathway blocker PD98059 abolished these effects of Ucn. Our findings further support the hypothesis that the changes of sACE activity and the production of other RAS components may play roles in the vasodilatory property of Ucn via the activation of the ERK1/2 pathway.


Yang X.,Nanchang University
Wei sheng wu xue bao = Acta microbiologica Sinica | Year: 2011

Denitrifying bacteria play an important role in the biological nitrogen removal process, especially the aerobic denitrifying bacteria. However, there are few studies on aerobic denitrifying bacteria. The present study aimed at the isolation of aerobic denitrifying bacteria with high ammonium and nitrite nitrogen removing ability from environmental samples, and its phylogeny and denitrifying characteristics. Based on the aerobic denitrifying activity, ammonium and nitrite nitrogen removing ability, the strains were isolated from sludge, water and sediment in a eutrophicated pond. A strain with the highest activities was identified according to its morphological, physiological and biochemical properties and phylogenetic analysis of its 16S rRNA sequence. By using NO(3-)-N, NH(4+)-N and NO(2-)-N as the sole nitrogen source respectively, its denitrifying characteristics, and the effects of culture conditions such as initial pH of medium, temperature, carbon source, shaking speed on the ability of removing ammonium and nitrite nitrogen, were investigated under aerobic condition. Among the isolated strains, strain C-4 showed the highest ability of removing ammonium and nitrite nitrogen. Strain C-4 was identified as Acinetobacter sp.. Under the conditions of sodium citrate as carbon source, temperature 30 degres C, shaking speed 120 r/min, cell age of 18 h, pH 8.5 for 200 mg/L NH(4+)-N medium and pH 7.5 for 100 mg/L NO(2-)-N medium, the net removal efficiency of nitrogen were 65.8% and 47.8% after 15 h and 12 h, respectively. An aerobic denitrifying strain Acinetobacter sp. C-4 (HQ896038) was isolated from water pond, and it exhibited high net removal efficiency of nitrogen in relative media. The net removal efficiency of nitrogen of strain C-4 was 73.04% in dealing with a eutrophicated pond water.


The aim of this work is to examine the environmental dependence of stellar velocity dispersion in local galaxies. In studies that likely suffer from the radial selection effect, one has a preference for the use of volumelimited samples. Two volume-limited samples with different redshift and luminosity ranges were constructed from the Main galaxy data of the Sloan Digital Sky Survey Data Release 10 (SDSS DR10). Considering some drawbacks of volume-limited samples, the apparent magnitude-limited Main galaxy sample was also applied. Statistical analyses in these different galaxy samples can reach the same conclusion: galaxies with large stellar velocity dispersions exist preferentially in high density regimes, while galaxies with small stellar velocity dispersions are located preferentially in low density regions, which is inconsistent with that obtained at intermediate redshifts. © Xin-Fa Deng 2015.


Dai M.,Nanchang University
Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery | Year: 2011

Metal wear products cause the aseptic loosening of joint prosthesis. To investigate the effect of metal ions Co2+ and Cr3 on the osteoblast apoptosis, cell cycle distribution, and secretion of alkaline phosphatase (ALP), and to search a method to prevent and treat aseptic loosening. The mouse calvarial osteoblasts (MC3T3-E1) were cultured in vitro to 3-5 generations (5 x 10(5) cells/mL) and divided into 2 groups: the experimental group and the control group. The osteoblasts were cultured in alpha-MEM medium containing 10% FBS (the control group), and the mixed solution of CoCl2 and CrCl was added after the osteoblasts cultured in alpha-MEM medium containing 10%FBS attached completely (the experimental group). At 12, 24, and 48 hours after culture, the osteoblast apoptosis and the cell cycle distribution were assessed by flow cytometry; and ELISA method was applied to detect ALP content in serum supernatant. At 12, 24, and 48 hours after culture, the apoptosis rates in the experimental group (13.90% +/- 0.52%, 14.80% +/- 0.41%, and 13.40% +/- 0.26%) were significantly higher than those in the control group (8.56% +/- 0.31%, 8.19% +/- 0.24%, and 2.15% +/- 0.11%), (P < 0.05); G2M (dividing phase) distribution ratio significantly decreased and G0G1 (dormancy stage) distribution ratio significantly increased when compared with those in the control group (P < 0.05); and the absorbency (A) values of ALP were 0.955 +/- 0.052, 0.624 +/- 0.041, and 0.498 +/- 0.026 in the experimental group, and were 1.664 +/- 0.041, 1.986 +/- 0.024, and 2.192 +/- 0.041 in the control group, showing significant differences between 2 groups (P < 0.05). Metal ions Co2+ and Cr3+ have a marked effect on osteoblasts cell cycle distribution, which can make most of the cells to be in dormancy stage (G0G1), up-regulate the apoptosis rate and inhibit the releasing of ALP from osteoblasts.


Zhong S.,Beijing University of Chemical Technology | Zhan C.,Nanchang University | Cao D.,Beijing University of Chemical Technology
Carbon | Year: 2015

A series of nitrogen-doped porous carbons are prepared from nitrogen-containing zeolitic imidazolate framework (ZIF) and additional carbon sources (including melamin, urea, xylitol and sucrose) via co-carbonization at T = 950 °C. Results indicate that macromolecular carbon sources, say, sucrose, can effectively protect the nitrogen loss from ZIF backbone owing to the pre-melting and polymerization of the sucrose adsorbed on the ZIF surface in the carbonization process, which makes the corresponding ZIF-derived porous Carbon-ZS have high nitrogen content and excellent capacitive performance. The specific capacitance of Carbon-ZS in 6 M KOH solution reaches 285.8 F g-1 at a current density of 0.1 A g-1 owing to its relatively high nitrogen content and proper hierarchical pore structure. In particular, the capacitance of Carbon-ZS is higher than previously reported IRMOF-derived carbon, ZIF-67-derived carbon and ZIF-8/furfuryl alcohol co-derived carbon. Besides high capacitance, moreover, Carbon-ZS also shows excellent cycling stability and good electric conductivity as electrode materials for electric double-layer capacitors. © 2014 Elsevier Ltd. All rights reserved.


Liao Q.-H.,Nanchang University
Guangdianzi Jiguang/Journal of Optoelectronics Laser | Year: 2012

The entanglement dynamics of two atoms initially in an entangled state system interacting with a bimodal field is investigated by making use of the concurrence and linear entropy. The effect of the initial entanglement degree of two atoms and the cavity field on the time evolution of concurrence is analyzed. The results show that the phenomenon of sudden death of the entanglement between two atoms occurs. The length of the death time interval is independent of the initial entanglement degree of two atoms. However, the death time depends on the initial entanglement degree of the cavity field. The atom and the field are entangled during all the evolution process.


Deng Z.,Nanchang University
Journal of Chinese Institute of Food Science and Technology | Year: 2014

The importance of the balance of fatty acids in vegetable blend oils to nutrition of human as well as the existing problems of consumption vegetable blend oils in China were discussed in this paper on the base of the relationship between fatty acids and human health, the effects of fatty acid balance on the human health, the vegetable blend oil consumptions situation in China, and the possible risks to human health. Furthermore, we proposed the possible solutions and countermeasures to the problem of vegetable blend oils. From a scientific and practical point of view, the national standards of recommended main indicators in vegetable blend oils were better considered as SFA : MUFA : PUFA, n-6PUFA : n-3PUFA, antioxidants and other physical, chemical and hygiene indicators.


Yu L.,Nanchang University | Nogami M.,Nagoya Institute of Technology
Materials Letters | Year: 2010

ZnMoO4:Eu3+ nanocrystals were synthesized by a mild and simple hydrothermal method. The results indicate that the pH value of the precursor solution plays a crucial role in controlling the morphology, size and structures. The leaflike, nanorods and nanowires were obtained by modulating the pH value of the precursor solution. The crystalline structure of ZnMoO4:Eu3+ nanocrystals are affected by the precursor solution. The excitation and emission spectra were studied. The results indicate that relative intensity of f-f transitions to charge transfer (CT) absorption and 5D0-7F2 to 5D0-7F1 transitions greatly change in different samples. © 2010 Elsevier B.V. All rights reserved.


China has witnessed a fast economic growth in the recent two decades. However, the heavy energy exploitation seems to show a negative relation to regional economic growth. Thus, the issue is whether the energy production is a curse or blessing for the regional economic growth in China. The present study deploys a comprehensive approach to rigorously prove the validity of a proposed panel data model that includes a second generation panel unit root test and panel cointegration and a spatial panel model. The results from the second generation panel unit root test and panel cointegration allowing for cross-sectional dependences show the differenced series are stationary and there exists a cointegration relationship among these variables for all sub-regions. The results from the spatial panel data model support the conjecture of the spatial dependent and show that there is a "resource curse" only for the Western region and Central region in China. © 2013 by the authors; licensee MDPI, Basel, Switzerland.


Zeng S.Y.,Nanchang University
Zhonghua fu chan ke za zhi | Year: 2013

To analyze the clinicopathologic features of mucinous cervical adenocarcinoma (ADC) and supply some reference for its diagnosis, treatment and prognosis. Totally 88 cases with primary mucinous ADC diagnosed between January 2003 and December 2007 in Jiangxi Maternal and Child Health Hospital were retrieved. Their clinical and pathological data were reviewed and analyzed. Among 88 patients, 70 cases of them were endocervical ADC, 11 cases were minimal deviation adenocarcinoma (MDA), 2 cases were intestinal subtype and 5 cases were villoglandular ADC. The positive rate of cervical Pap smear cytology was only 28% (10/36). There were 10 cases were performed several times of cervical Pap smear cytology test and biopsies, while still no abnormality was found. Finally, 7 cases of them were diagnosed by cervical excisional biopsy and endocervical curettage, including 5 cases with endocervical ADC and 2 cases with MDA; 2 cases (1 case with stage Ib1 endocervical ADC and 1 case with Ib1 MDA) were diagnosed by cold knife conization, and 1 case with stageIb1 endocervical were diagnosed by uteroscopically directed biopsy. The overall 5-year survival rate was 60.0%. Using univariate analysis results showed that age (P = 0.046), stage (P = 0.007), tumor size (P = 0.007) and therapeutic methods (P = 0.009) were significant prognostic factors. Multivariate analysis showed that therapeutic methods was an independent predictor for survival (P = 0.013). Stage IIb-IIIb MDA patients occupied 7/11 of all MDA patient, while there was only one such patient of 5 cases with villoglandular ADC. The overall HPV infection rate was 65% (57/88), and there was no obvious differences about the HPV infection rates among different types of mucinous ADC. Cervical smear cytology is of little significance to the diagnosis of mucinous cervical adenocarcinoma. Early stage mucinous ADC is difficult to be detected, especially for MDA. Cervical excisional biopsy, endocervical curettage, cold knife conization, uteroscope are beneficial to its diagnosis. Therapeutic methods is an important prognostic factor for mucinous ADC and comprehensive treatment should be given to those patients with risky postsurgical factors.


Jiang D.-Y.,Nanchang University
International Journal of Theoretical Physics | Year: 2014

With spin squeezing parameter we investigate the entangled property of a multipartite state superposed by three Dicke states with arbitrary relative phases. We first derive the mean spin direction, the optimally squeezed angle, and then numerically calculate the dependence of spin squeezing parameter on the superposition coefficients, the relative phases and the forms of the Dicke states. It’s shown that the entangled property depends on these parameters. © 2014, Springer Science+Business Media New York.


Niu C.,University of Chinese Academy of Sciences | Tian Y.,University of Chinese Academy of Sciences | Wu X.-N.,CAS Academy of Mathematics and Systems Science | Wu X.-N.,Chinese Academy of Sciences | And 2 more authors.
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2012

The dual fluid description for a general cutoff surface at radius r=r c outside the horizon in the charged AdS black brane bulk space-time is investigated, first in the Einstein-Maxwell theory. Under the non-relativistic long-wavelength expansion with parameter ε, the coupled Einstein-Maxwell equations are solved up to O(ε2). The incompressible Navier-Stokes equation with external force density is obtained as the constraint equation at the cutoff surface. For non-extremal black brane, the viscosity of the dual fluid is determined by the regularity of the metric fluctuation at the horizon, whose ratio to entropy density η/s is independent of both the cutoff r c and the black brane charge. Then, we extend our discussion to the Gauss-Bonnet-Maxwell case, where the incompressible Navier-Stokes equation with external force density is also obtained at a general cutoff surface. In this case, it turns out that the ratio η/s is independent of the cutoff r c but dependent on the charge density of the black brane. © 2012 Elsevier B.V.


Peng B.-X.,Jiangxi Normal University | Wu D.-S.,Nanchang University
Ranliao Huaxue Xuebao/Journal of Fuel Chemistry and Technology | Year: 2014

The bromine content of 305 coal samples from 27 provinces, municipalities and autonomous regions of China were tested, then the distribution of bromine with different geological ages, coal ranks, coal-cumulating areas was analyzed. The results show that the coals with moderate and low bromine content are predominant in China. The bromine content ranges from 0.12 to 69.66 μg/g, and it follows a logarithm normal distribution. Thus the geometric mean, 7.04 μg/g, is regarded as the average bromine content in Chinese coals. This is less than that in many countries and close to the average bromine content (7.10 μg/g) in Japanese coals. In Chinese coals, the average bromine content is less than 5 μg/g in 13 districts, 5~15 μg/g in 9 areas, and more than 15 μg/g in 5 regions. Based on coal rank, bromine content decreases gradually from bituminous coal, anthracite, lignite to subbituminous coal. As for coal-forming period, bromine content decreases from Early carboniferous through Late Permian, Late Carboniferous, Early Permian, Middle Jurassic, Late Triassic, Early Jurassic, Late Jurassic, Tertiary to Middle Carboniferous. According to coal-cumulating areas, bromine content decreases from northwestern China, northern China, southern China, Yunnan and Tibet to northeastern China. But all of them have no notable effect on the bromine content in Chinese coal.


Shen Y.,Nanchang University | Yu G.P.,Wuhan University | Wang G.P.,Wuhan University
Applied Physics Letters | Year: 2011

We numerically show slow light can be achieved in one dimensional metallic-dielectric photonic crystals as a result of sign change of the effective dielectric constant. Due to the occurrence of slow light, rainbow trapping effect is realizable in chirped one dimensional metallic-dielectric photonic crystals where thicknesses of metal slabs linearly increase. The results imply the potential applications in constructing nanoscale optical buffer, memories, filter, sorter, etc. for high density integration of optical circuits. © 2011 American Institute of Physics.


Zhou W.,Central South University | Zhou W.,Nanchang University | Liu Y.,Central South University | Zhong D.-W.,Central South University
Tumor Biology | Year: 2013

Associations between adiponectin (ADIPOQ) genetic polymorphisms (rs2241766 G/T and rs266729 G/C) and cancer risk have been extensively studied in the past decade, while conflicting results were reported. Therefore, this study would explore the associations by using a meta-analysis. The databases of Medline, Embase, and Wangfang were retrieved, and the latest updated time was 1 August 2012. Effect sizes of odds ratio and 95 % confidence interval (OR and 95 % CI) were calculated by using a fixed- or random-effect model. A total of 12 studies with 10,368 participants were identified for association between ADIPOQ rs2241766 G/T and risk of cancer, and ten studies with 12,665 participants were for association between ADIPOQ rs266729 G/C and risk of cancer. Overall combined analyses indicated that neither ADIPOQ rs2241766 G/T nor rs266729 G/C was associated with risk of cancer incidence (OR (95 % CI), 0.89 (0.61-1.30) for GG vs. TT and 0.94 (0.83-1.06) for G carriers vs. T carriers for rs2241766 G/T; 0.99 (0.85-1.16) for GG vs. CC and 0.96 (0.87-1.06) for G carriers vs. C carriers for rs266729 G/C). When stratified analyses were conducted according to the participants' ethnicity, sources of controls, types of cancer, and sample size, we found that G allele of ADIPOQ rs2241766 G/T was significantly associated with decreased risk of cancer based on population-based case-control studies (OR (95 % CI), 0.65 (0.50-0.85) for GG vs. TT and 0.88 (0.79-0.98) for G carriers vs. T carriers). In contrast, there was no association between rs266729 G/C polymorphism and risk of cancer when subgroup analyses were conducted. In summary, this meta-analysis indicated that ADIPOQ rs2241766 G/T rather than rs266729 G/C polymorphism was closely associated with risk of cancer development. © 2012 International Society of Oncology and BioMarkers (ISOBM).


Zhou W.,University of Michigan | Zhou W.,Nanchang University | Wei W.,Beth Israel Deaconess Medical Center | Sun Y.,University of Michigan
Cell Research | Year: 2013

The SCF (SKP1 (S-phase-kinase-associated protein 1), Cullin-1, F-box protein) E3 ubiquitin ligases, the founding member of Cullin-RING ligases (CRLs), are the largest family of E3 ubiquitin ligases in mammals. Each individual SCF E3 ligase consists of one adaptor protein SKP1, one scaffold protein cullin-1 (the first family member of the eight cullins), one F-box protein out of 69 family members, and one out of two RING (Really Interesting New Gene) family proteins RBX1/ROC1 or RBX2/ROC2/SAG/RNF7. Various combinations of these four components construct a large number of SCF E3s that promote the degradation of many key regulatory proteins in cell-context, temporally, and spatially dependent manners, thus controlling precisely numerous important cellular processes, including cell cycle progression, apoptosis, gene transcription, signal transduction, DNA replication, maintenance of genome integrity, and tumorigenesis. To understand how the SCF E3 ligases regulate these cellular processes and embryonic development under in vivo physiological conditions, a number of mouse models with transgenic (Tg) expression or targeted deletion of components of SCF have been established and characterized. In this review, we will provide a brief introduction to the ubiquitin-proteasome system (UPS) and the SCF E3 ubiquitin ligases, followed by a comprehensive overview on the existing Tg and knockout (KO) mouse models of the SCF E3s, and discuss the role of each component in mouse embryogenesis, cell proliferation, apoptosis, carcinogenesis, as well as other pathogenic processes associated with human diseases. We will end with a brief discussion on the future directions of this research area and the potential applications of the knowledge gained to more effective therapeutic interventions of human diseases. © 2013 IBCB, SIBS, CAS. All rights reserved.


Zou W.,Nanchang University
Acta Mechanica Sinica/Lixue Xuebao | Year: 2015

In the classical theory of elasticity, a body is initially modeled as a homogeneous and dense assemblage of constituent “material particles”. The kernel concept of elastic deformation is the displacement of the particle that associates the current configuration with the reference one. In this paper, we exploit an alternative constituent “micro-finite element”, and use the stretch of the element as the essential quality to recast the theory of elasticity. It should be realized that such a treatment means that the elastic body can be modeled as a finite covering of elements and consequently characterized by a manifold. The recasting of the elasticity theory becomes more feasible for dealing with defects and topological evolution. © 2015 The Chinese Society of Theoretical and Applied Mechanics; Institute of Mechanics, Chinese Academy of Sciences and Springer-Verlag Berlin Heidelberg


Mao Q.,Nanchang University
Mathematical and Computer Modelling | Year: 2011

The Adomian decomposition method (ADM) is employed in this paper to investigate the free vibrations of the Euler-Bernoulli beams with multiple cross-section steps. The proposed ADM method can be used to analyze the vibration of beams consisting of an arbitrary number of steps through a recursive way. The solution can be obtained by solving a set of algebraic equations with only three unknown parameters. Furthermore, the method can be extended to obtain an approximate solution to vibration problems of any type of non-uniform beams. Several numerical examples are presented and compared to those given in the paper. It is shown that the ADM offers an accurate and effective method of free vibration analysis of multiple-stepped beams with arbitrary boundary conditions. © 2011 Elsevier Ltd.


Yang Z.,Nanchang University
Revista Tecnica de la Facultad de Ingenieria Universidad del Zulia | Year: 2016

By analyzing the bottleneck facing the current power transformer fault diagnosis model, this paper puts forward a power transformer fault diagnosis model. The SOM model is introduced to optimize the training samples collected and to eliminate interference sample data existing in training samples of various types. At last, various excellent samples are extracted as the input information of the BP network to build the power transformer fault diagnosis model. The model analysis results suggest that various training samples extracted and optimized by the SOM network can efficiently improve the recognition and diagnosis performance of the BP network. Besides, its diagnosis accuracy is higher than that of traditional algorithms by more than 10%.


Nie W.,Jiangxi University of Traditional Chinese Medicine | Liao Q.,Harbin Institute of Technology | Zhang C.,Jiangxi University of Traditional Chinese Medicine | He J.,Nanchang University
Energy | Year: 2010

An irreversible cycle model of the micro-/nanoscaled Otto engine cycle with internal friction loss is established. The general expressions of the work output and efficiency of the cycle are calculated based on the finite system thermodynamic theory, in which the quantum boundary effect of gas particles as working substance and the mechanical Casimir effect of gas system are considered. It is found that, for a micro-/nanoscaled Otto cycle devices, the work output W and efficiency η of the cycle can be expressed as the functions of the temperature ratio τ of the two heat reservoirs, the volume ratio rV and the surface area ratio rA of the two isochoric processes, the dimensionless thermal wavelength λ and other parameters of cycle, while for a macroscaled Otto cycle devices, the work output W0 and efficiency η0 of the cycle are independent of the surface area ratio rA and the dimensionless thermal wavelength λ. Further, the influence of boundary of cycle on the performance characteristics of the micro-/nanoscaled Otto cycle are analyzed in detail by introducing the output ratio W/W0 and efficiency ratio η/η0. The results present the general performance characteristics of a micro-/nanoscaled Otto cycle and may serve as the basis for the design of a realistic Otto cycle device in micro-/nanoscale. © 2010 Elsevier Ltd.


Tian H.Y.,Nanchang University
Zhongguo zhen jiu = Chinese acupuncture & moxibustion | Year: 2011

To compare the therapeutic effect between surround needling plus thin cotton moxibustion and western medicine for herpes zoster. Eighty cases were randomly divided into a surround needling plus thin cotton moxibustion group (observation group, n = 42) and a western medicine group (control group, n = 38) with a randomized controlled method. The observation group was treated with surround needling around the herpes and thin cotton moxibustion on the surface of the herpes, and the control group with oral administration of Acyclovir tablet plus topical Acyclovir cream. The scores of pain, quantity of herpes, herpes color, anabrosis and exudation changes of herpes and the markedly effective rate in the two groups were compared before and after treatment. The markedly effective rate was 78.6% (33/42) in the observation group, which was superior to 39.5% in the control group (P < 0.05). All the symptom scores in both the groups were improved obviously after treatment (all P < 0.05), and the observation group was better than the control group (all P < 0.05). The therapeutic effect of surround needling plus thin cotton moxibustion on herpes zoster is superior to that of routine western medicine.


Deng X.-F.,Nanchang University
Revista Mexicana de Astronomia y Astrofisica | Year: 2015

The aim of this study is to examine the environmental dependence of the u - r , u - g , g - r , r - i and i - z colors in the loz z sample of the Sloan Digital Sky Survey Data Release 10 (SDSS DR10). To decrease the radial selection effect, I divide the low z sample into subsamples with a redshift binning size of Δz=0.01 and analyze the environmental dependence of colors for these subsamples in each redshift bin. The statistical results show that all five colors of galaxies in the low z sample are weakly correlated with the local environment, which is consistent with the results of main galaxies at z > 0.15 and CMASS galaxies. © Copyright 2015: Instituto de Astronomía, Universidad Nacional Autónoma de México.


Yu L.,Nanchang University
Kuei Suan Jen Hsueh Pao/Journal of the Chinese Ceramic Society | Year: 2010

Glasses with the composition of xZnO-(100-x)SiO2 (x=0, 5, 10, 20, mole ratio, the same below) were prepared by the sol-gel method. Effect of ZnO content on the luminescent intensity of Dy3+ was studied. Moreover, the luminescent properties of Dy3+ in ZnO-SiO2 glasses were investigated under the ultraviolet light and femtosecond (fs) laser (800 nm) excitation. The results indicate that the luminescent intensity of Dy3+ hardly changes as ZnO content is 0, 5% and 10%. When ZnO content increases to 20%, the luminescent intensity of Dy3+ remarkably enhances, which can be attributed to the great changes of the host microstructures. The upconversion luminescence (UCL) properties of Dy3+ in ZnO-SiO2 glasses were studied. Strong UCL of Dy3+ in SiO2 and ZnO-SiO2 glasses was observed at fs laser excitation. The photoluminescent intensity of Dy3+ as the fs laser pump power indicates that the two-photon absorption dominates the upconversion luminescence. According to the energy level analysis of Dy3+, the UCL mechanism of Dy3+ in both SiO2 and ZnO-SiO2 glasses is attributed to excited state absorption.