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Rajesh N.,CSIR - Central Electrochemical Research Institute | Sarma R.,Nalbari College Nalbari | Prajapati D.,CSIR - Central Electrochemical Research Institute
Synlett | Year: 2014

A one-pot, three-component method for the synthesis of benzo-fused quinolines has been developed by tandem reaction between phenylacetylenes and naphthylamines. The first step of the reaction is hydroamination of the alkyne followed by a hydroarylation reaction to form the quinolines. Indium(III) trifluoromethanesulfonate was shown to be an efficient catalyst for the transformations, and the reaction proceeded in the absence of any other co-catalyst or additive to give the corresponding quinolines in good to excellent yields. © Georg Thieme Verlag Stuttgart . New York. Source

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