Igata A.,Nagoya University of Arts and Sciences
Proceedings of the Japan Academy Series B: Physical and Biological Sciences | Year: 2010
Throughout my research life, I experienced to discover the causes of some neurological diseases in Japan. 1) SMON (subacute myelo-optico-neuropathy). Since the early 1960s, a peculiar neurological disease became prevalent throughout Japan. Through the chemical analysis of the green urine, characteristic of this disease, it was found that this disease was caused by intoxication of the administered clioquinol, an anti-diarrheal drug. This discovery is a big topic in the history of Japanese medicine. 2) In early 1970s, I experienced many young patients with oedema and polyneuropathy in Kagoshima. Finally it was found that the disease was the long-forgotten beriberi, which had disappeared several decades ago. We must always be aware of beriberi even now, as far as we eat well-polished rice. 3) In 1972, we noticed a group of sporadic paraparesis in Kagoshima, which was 20 years later confirmed to be induced by human T lymphotropic virus type-I (HTLV-I). We named this disease as "HTLV-I associated myelopathy" (HAM). It gave a strong impact that the causative virus of adult T cell leukemia (ATL) can induce entirely different diseases, in terms of both the clinical course and the pathological features. It was also proven that HAM was identical with tropical spastic paraparesis, (TSP), which had been prevalent in many areas of tropical zones. These experiences are good examples of our slogan "to keep in mind to send message of scientific progress from the local area to the international stage". © 2010 The Japan Academy.
Shimokata H.,Nagoya University of Arts and Sciences |
Ando F.,Aichi Shukutoku University |
Yuki A.,Kochi University |
Otsuka R.,National Center for Geriatrics and Gerontology
Geriatrics and Gerontology International | Year: 2014
Aim: The present study aimed to evaluate age-related changes in skeletal muscle mass among community-dwelling middle-aged and elderly Japanese. Methods: This 12-year longitudinal study of a community-dwelling population in Japan included 15948 examinations of 1962 men and 1990 women. We assessed appendicular muscle mass (AMM) using dual X-ray absorptiometry and calculated the skeletal muscle index (SMI) using the AMM divided by height squared (kg/m2). Low muscle mass was defined as muscle mass minus two standard deviations below the mean for young healthy adults. Leg extension power (watts) was measured as an index of muscle function. Longitudinal data of skeletal muscle mass were analyzed using a general linear mixed-effect model. Results: The prevalence of low muscle mass at the first wave of examinations was 27.1% in men and 16.4% in women. Longitudinal analysis showed that skeletal muscle mass decreased with aging during the 12-year study period except in middle-aged men, and to a greater extent in elderly men (P for trend, <0.001). Skeletal muscle mass decreased slightly, but significantly, in women. Although a cross-sectional analysis showed that SMI did not differ with age in women, leg extension power per leg muscle mass and grip strength per arm muscle mass as indices of muscle quality were significantly lower in older women (P for trend, <0.001 for both). Conclusion: Age-related decreases in muscle mass were trivial, especially in women, but the quality of muscle decreased with aging in both sexes. © 2014 Japan Geriatrics Society.
Igata A.,Nagoya University of Arts and Sciences
Polskie Archiwum Medycyny Wewnetrznej | Year: 2012
Personal experience of the discovery of the cause, pathophysiology, and treatment as well as prevention of subacute myelo-optic neuropathy, beriberi, and HTLV-I-associated myelopathy were described. Copyright by Medycyna Praktyczna, Kraków 2012.
Kawahara K.,Nagoya University of Arts and Sciences |
Narikawa M.,Design Engineering Inc.
Applied Ergonomics | Year: 2015
Unique efforts of the Japanese industries in meeting the needs of the super-aged society are introduced through their association with International Association for Universal Design (IAUD). Considerations are made on how successes were brought about, what can be learned as well as what issues should be addressed in the future. © 2014.
Horio M.,Nagoya University of Arts and Sciences
Journal of Japan Industrial Management Association | Year: 2011
Generally, significant work is required to make a university timetable. Although attempts have been made to automate this work using a computer system, the cost of introducing and establishing widespread use of the system in many universities has been too high. In this research, we have developed a system for generating university timetables for the School of Human Care Studies at Nagoya University of Arts and Sciences. The system has the following features. - Anyone can obtain a suitable timetable and operation is simple. We also added some practical functions required by the school administrator. - Dramatically reduces the time required to make a timetable; practical use enabling creation of a timetable for an actual university faculty in several seconds. - Low cost and short time required to construct the system; the user interface employs a popular spreadsheet program and we used our development of a general project scheduling solver. This system is flexible and practical, and is able to propose an actual timetable plan. In addition, we gave the timetable planner at the School of Human Care Studies permission to use the system and a simple operation manual. The system will be used in the future to make actual timetables at this university.