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Nagoya, Japan

Nagoya University , abbreviated to Meidai , is a Japanese national university headquartered in Chikusa-ku, Nagoya. It is the last Imperial University in Japan and among the National Seven Universities. It is the 4th best ranked higher education institution in Japan.As of 2014, six faculty and alumni of the university have won the Nobel Prize in science. Wikipedia.

Yamamoto Y.,Nagoya University
Chemical Society Reviews | Year: 2014

Transition-metal (TM)-catalyzed hydroarylation reactions of alkynes have received much attention, because they enable the net insertion of alkyne C-C triple bonds into C-H bonds of aromatic precursors, resulting in regio- and stereo-selective formation of synthetically useful arylalkenes. Taking advantage of this feature, TM-catalyzed alkyne hydroarylations have been successfully used for the synthesis of heterocycles. TM-catalyzed alkyne hydroarylations can be classified into three major categories depending on the type of reaction and precursors involved: (1) palladium-catalyzed reductive Heck reactions of alkynes with aryl halides, (2) TM-catalyzed conjugate arylation reactions of activated alkynes with arylboronic acids, and (3) TM-catalyzed aromatic C-H alkenylations with alkynes. This review surveys heterocycle synthesis via TM-catalyzed hydroarylation of alkynes according to the above classification, with an emphasis on the scope and limitations, as well as the underlying mechanisms. © 2014 The Royal Society of Chemistry. Source

Yamamoto Y.,Nagoya University
Chemical Reviews | Year: 2012

The transition-metal-catalyzed cycloisomerizations of α,ω- dienes have been continuously investigated because such cycloisomerization reactions provide atom-economical routes to various carbo- and heterocyclic compounds. Nevertheless, early catalytic systems generally lacked the requisite isomeric selectivity and the general substrate scope. Considerable efforts devoted to the identification of selective and versatile catalyst systems have led to recent developments of late-transitionmetal-catalyzed cycloisomerizations of 1,6-dienes with wide substrate scope and high isomeric selectivity, including asymmetric cycloisomerizations. There is, nevertheless, room for improvement of the substrate scope, the isomeric selectivity, and the enantiomeric selectivity. In addition, by combining the newly developed catalytic systems with state-of-the-art techniques such as a microwave treatment and the use of unique solvent systems, further progress in diene cycloisomerizations is being made possible. For xample, recyclable catalyst systems for the 1,6-diene cycloisomerization have been established using ionic liquids and scCO2 as solvents. Further investigations into the utilization of heterogeneous catalysts and carbophilic Lewis acid catalysts as well as less examined substrates would result in the development of unprecedented modes of cycloisomerization and would increase the synthetic value of α,ω-diene cyclization. © 2012 American Chemical Society. Source

This is a personal history of one of the Japanese researchers engaged in developing a method for growing GaN on a sapphire substrate, paving the way for the realization of smart television and display systems using blue LEDs. The most important work was done in the mid to late 1980s. The background to the author's work and the process by which the technology enabling the growth of GaN and the realization of p-type GaN was established are reviewed. © 2015 Nobel Foundation. © 2015 Nobel Foundation, Published by The American Physical Society. Source

Nagoya University and Toyota Jidosha Kabushiki Kaisha | Date: 2015-02-05

A method and apparatus for producing core-shell type metal nanoparticles which are excellent in productivity are provided, in particular, the present invention provides a method of production of core-shell type metal nanoparticles including (a) a step of introducing a solution of a salt of a first metal to a first flow path of a flow type reaction apparatus and applying plasma to the solution of the salt of the first metal in the first flow path to obtain a solution which contains metal nanoparticles of the first metal and (b) a step of introducing a solution of a salt of a second metal to a second flow path of the flow type reaction apparatus, making it merge with the solution which contains metal nanoparticles of the first metal to obtain a mixed solution, and applying plasma to the mixed solution to cover the metal nanoparticles of the first metal by the second metal.

Antibodies are provided that specifically bind to Acting Binding Protein Girdin (Akt Phosphorylation Enhancer), a new substrate of serine/threonine kinase. Additionally, methods of making hybridomas for producing said antibodies and methods of detecting girdin using said antibodies are provided herein. The antibodies and methods are useful for detecting girdin in tissue samples, such as tissue samples from subjects having or suspected of having a disorder in which any of cell motility, cell movement, and angiogenesis is involved.

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