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Pinchuk T.V.,Russian National Research Medical University | Fedulaev Y.N.,Russian National Research Medical University | Denisova N.N.,Municipal Clinical Hospital No 13 | Chura O.V.,Municipal Clinical Hospital No 13 | Logunova I.Y.,Municipal Clinical Hospital No 13
Bulletin of Experimental Biology and Medicine | Year: 2014

Proinflammatory markers were evaluated in patients with chronic heart failure of ischemic origin and essential hypertension with preserved left-ventricular ejection fraction before and after a 6-month course of simvastatin therapy (20 mg/day). The study was carried out in 125 patients with diastolic dysfunction manifested as impaired relaxation and pseudonormalization. The main group received standard therapy for chronic heart failure and simvastatin, controls received only standard therapy. In addition, the results in the main group were compared in patients with different types of left-ventricular diastolic dysfunction. Simvastatin therapy significantly reduced the levels of C-reactive protein and IL-6. © 2014, Springer Science+Business Media New York.

Khasanova G.M.,Municipal Clinical Hospital No 13 | Tutelyan A.V.,Central Scientific Research Institute
Voprosy Pitaniia | Year: 2011

Actual consumption of vitamins A, E, β-carotene, ascorbic acid, thiamin, pyridoxine and main foodstuffs by recovered patients suffered from hemorrhagic fever with renal syndrome has been given. Frequency analysis of foodstuffs consumption was used to study actual nourishment of recovered patients. Surplus consumption of fat mainly due to the use of saturated fatty acids, deficiency of poly unsaturated fatty acids, surplus sugar consumption and predominance of proteins of animal origin over proteins of vegetable origin in ration has been revealed. Deficiency of water soluble vitamins equals to 41,6-78,7% of all examined patients, deficiency of fat water soluble vitamins is lower (21,4-38,3%).

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