Gulbarga, India
Gulbarga, India

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Sagare P.,Mrmedical College | Patil S.K.,Mrmedical College
International Journal of Pharma and Bio Sciences | Year: 2010

Skin psoriasis which is a common chronic inflammatory dermatosis affecting 1% to 2% of people in the general. Keratolytic agents are helpful in reducing scale and hyperkeratosis by causing softening and desquamation of the stratum corneum and most beneficial in extremely thick or scaly psoriatic plaques. In the present study Salicylic acid chosen as model drug which is the most effective keratolytic agent. In present work o/w emulsion based cream formulation contain suitable combination of oil phase and aqueous phase along with preservatives, prepared and subjected to various physiochemical parameters like drug content, pH, spread ability, tube extrude ability, viscosity and IR studies. In-vitro drug release was carried out in phosphate buffer (pH 7.4) and compared with marketed formulation. Stability studies of selected formulation were also done at ambient temperature (30°C & 40° C) for the period of six months as per ICH guidelines. The selected formulation were subjected for primary skin irritation test in rabbits, guinea pigs, and healthy human volunteers for 72 hours and observed for any skin rashes, inflammation, itching, or redness on applied portions. Drug content, pH, Spread ability, Tube extrude ability of the formulation was found to be 95.00%, 6.1, 11.32gm.cm/sec, 94.96% respectively. From rheogram it is concluded that formulation shows pseudo plastic flow property.


Babladi P.I.,Mrmedical College | Vijayanath V.,Ss Institute Of Medical Science | Vijayamahantesh S.N.,Snijalingappa Medical College
Medico-Legal Update | Year: 2010

Deaths due to burns are common causes of unnatural deaths contributing nearly 25% of all autopsies. Dowry deaths are a menace to the society and many of these are caused by burns. In the current study a total of 525 cases of burns were analysed over a period of five years at Government General hospital Gulbarga. Of these 381(72.5%) cases were of female. During the five years the cases were almost evenly distributed with highest of 121 cases in the year 2000. out of the 525 cases studied 450 case were accidental in nature and 52 cases were suicidal and 23 cases were homicidal in nature based on history from the relatives and inquest papers furnished by police which some times was sketchy. Out of the 381 female cases, 92 were unmarried and the remaining 289 cases were of married females. Maximum numbers of cases i.e 289 were admitted to hospital and 92 were brought dead. Out of these 289 cases, a maximum of 74 cases survived for period of more than five years.


Imran S.S.,Mrmedical College | Uzair S.H.,Mr Medical College | Suntnoore D.,Bidar Institute of Medical science
Medico-Legal Update | Year: 2013

Though there are several parameters which help in identifying a person, stature of an individual is one of the important parameter, as it is an inherent characteristic. There is an established relationship between stature and dimensions of various parts of the body allowing the investigators to estimate the stature from available data. In the present study right footprint length, left footprint length and heights of 200 students(100 males and 100 females) studying in M.R. Medical College belonging to Gulbarga region are recorded for stature estimation. Significant and positive correlation coefficient has been shown to exist between stature and measurements of foot prints. The present study shows a significant correlation of stature with right and left foot print length (P<0.01). The results show that males are taller and their mean foot length is larger than that of females. There is no statistically significant difference in right and left footprint length in both the sexes (P>0.05). Either right or left footprint length may be used to predict the stature by regression formula. Regression equations are derived separately for individual foot length in both the sexes.


Vijayanath V.,Ssinstitute Of Medical Science And Research Center | Anitha M.R.,Ssinstitute Of Medical Science And Research Center | Raju G.M.,Jjm Medical College | Babladi P.,Mrmedical College
Biomedical Research | Year: 2010

Delinquent children belong to that category of exceptional children who exhibit considerable deviation in terms of their social adjustment and are consequently also labelled as socially deviant or socially handicapped. They are found to possess criminal tendencies and usually indulge in antisocial behaviour. In this sense, they are very much like criminals and antisocial elements. In legal terminology, however they are referred to as delinquents and not as criminals.


Sidhalingreddy,Mrmedical College | Sidhalingreddy,Snmedical College | Andola S.K.,Mrmedical College
Journal of Clinical and Diagnostic Research | Year: 2011

Background: Intra-abdominal masses always remain as an enigma in surgical practice. A documentary evidence of the nature of the pathology before the institution of therapy and for the prognosis is mandatory. FNAC is a substitute for surgical procedures like diagnostic laparotomy. Aims: To assess the utility of FNAC in the diagnosis of intraabdominal lesions. Objectives: To study the cytomorphological features, age and sex distribution of intra-abdominal lesions and to categorize them organwise and as inflammatory, benign and malignant lesions. To classify the malignant lesions according to their cell type. To evaluate the sensitivity, specificity and diagnostic accuracy. Materials and Methods: The study included 245 intra-abdominal lesions which were detected clinically or radiologically. The lesions were divided clinically into palpable and non-palpable lumps. USG or CT were used for all the non-palpable lesions and for a few palpable lesions and direct in selected palpable lesions. Giemsa's and Papanicolaou's stains were used. Results: The mean age was 45.16 years, with M:F of 1:1.3. The diagnostic yield was 92.1% in USG guided, 100% in CT guided and 95% in direct aspiration. There were 148 (60.3%) malignant, 55 (22.4%) benign, 25 (10.2%) inflammatory and one (0.6%) suspicious lesions and 16 (6.5%) unsatisfactory smears. The liver and the ovary were the most common sites. Adenocarcinomas and hepatocellular carcinomas were the most common malignant lesions. This study showed 94.1% sensitivity, 100% specificity, 100% positive predictive value, 92.3% negative predictive value and 96.5% diagnostic accuracy. Conclusion: Intra-abdominal FNA is a simple, economical and a safe procedure with high sensitivity, specificity and diagnostic accuracy and it can be utilized as a pre-operative procedure for the management of intra-abdominal lesions.


Babladi P.I.,Mrmedical College | Vijayanath V.,Ss Institute Of Medical Science And Research Center | Vijayamahantesh S.N.,Snijalingappa Medical College
Indian Journal of Forensic Medicine and Toxicology | Year: 2010

Deaths due to burns though rare in the western context are frequently encountered in the Indian scenario. A study was conducted at Government General Hospital Gulbarga over a period of five years to find out the incidence and influence of different factors leading to fatal burns injury. Out of the total 525 cases studied maximum were found in the age group of 20-30 years. 115 patients were brought dead and the remaining 410 succumbed later after the admission. Among these 161 cases survived for five days after the injury. Most common cause of death in our study was septicemia which accounted for 343 cases. Maximum number of deaths i.e., 450 was accidental in nature and least common was homicidal deaths accounting for only 23 cases. The paper also describes the comparison between our study and studies conducted by different authors across the country to find out the similarities and dissimilarities in various factors affecting the burns victims.


Babladi P.I.,Mrmedical College | Vijayanath V.,Ss Institute Of Medical Science And Research Center | Vijayamahantesh S.N.,Snijalingappa Medical College
Indian Journal of Forensic Medicine and Toxicology | Year: 2011

Deaths due to burns though rare in the western context are frequently encountered in the Indian scenario. A study was conducted at Government General Hospital Gulbarga over a period of five years to find out the incidence and influence of different factors leading to fatal burns injury. Out of the total 525 cases studied maximum were found in the age group of 20-30 years. 115 patients were brought dead and the remaining 410 succumbed later after the admission. Among these 161 cases survived for five days after the injury. Most common cause of death in our study was septicemia which accounted for 343 cases. Maximum number of deaths i.e., 450 was accidental in nature and least common was homicidal deaths accounting for only 23 cases. The paper also describes the comparison between our study and studies conducted by different authors across the country to find out the similarities and dissimilarities in various factors affecting the burns victims.


Sidhalingreddy,Mrmedical College | Andola S.K.,Mrmedical College
Journal of Clinical and Diagnostic Research | Year: 2011

Background: Intra-abdominal masses always remain as an enigma in surgical practice. A documentary evidence of the nature of the pathology before the institution of therapy and for the prognosis is mandatory. FNAC is a substitute for surgical procedures like diagnostic laparotomy. Aims: To assess the utility of FNAC in the diagnosis of intraabdominal lesions. Objectives: To study the cytomorphological features, age and sex distribution of intra-abdominal lesions and to categorize them organwise and as inflammatory, benign and malignant lesions. To classify the malignant lesions according to their cell type. To evaluate the sensitivity, specificity and diagnostic accuracy. Materials and Methods: The study included 245 intra-abdominal lesions which were detected clinically or radiologically. The lesions were divided clinically into palpable and non-palpable lumps. USG or CT were used for all the non-palpable lesions and for a few palpable lesions and direct in selected palpable lesions. Giemsa's and Papanicolaou's stains were used. Results: The mean age was 45.16 years, with M:F of 1:1.3. The diagnostic yield was 92.1% in USG guided, 100% in CT guided and 95% in direct aspiration. There were 148 (60.3%) malignant, 55 (22.4%) benign, 25 (10.2%) inflammatory and one (0.6%) suspicious lesions and 16 (6.5%) unsatisfactory smears. The liver and the ovary were the most common sites. Adenocarcinomas and hepatocellular carcinomas were the most common malignant lesions. This study showed 94.1% sensitivity, 100% specificity, 100% positive predictive value, 92.3% negative predictive value and 96.5% diagnostic accuracy. Conclusion: Intra-a bdominal FNA is a simple, economical and a safe procedure with high sensitivity, specificity and diagnostic accuracy and it can be utilized as a pre-operative procedure for the management of intra-abdominal lesions.


Umesh S.R.,Mrmedical College | Imran S.S.,Mr Medical College | Uzair S.H.,Mr Medical College
Medico-Legal Update | Year: 2013

Estimation of stature from various measurements of the body is vital to medicolegal investigations. Correlation coefficients and formulae derived for regression equation to estimate the approximate height are age and race specific.It is a cross-sectional study carried out to estimate stature from head length on 100 students of M.R.Medical College, Gulbarga aged above 21years hailing from Hyderabad Karnataka region and also to evaluate the correlation of body height and head length. A Positive and statistically significant correlation between total height and other cranial parameters like head height, head length & head breadth was observed in both the sexes (P< 0.01). The correlation coefficient between head length and stature is 0.664 in males, 0.661 in females, The results indicate that the cranial dimension like head length provides an important means in estimating the stature of an unknown individual. Regression equations derived - Ht = (a) + (b) x Head length can be used to estimate the stature, in this Hyderabad Karnataka region.

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