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Mother and, France

Monteil J.,University of Limoges | Maubon A.,University of Limoges | Leobon S.,University of Limoges | Roux S.,University of Limoges | And 5 more authors.
Anticancer Research | Year: 2011

Background: To assess pelvic (P) and/or paraaortic (PA) lymph node (LN) involvement in patients with primary stage IA-IVA cervical cancer, 18F-fluorodeoxyglucose (FDG)-PET, and MRI were compared with histological results. Materials and Methods: Forty patients were prospectively evaluated. Twenty-eight patients underwent radio-chemotherapy (RT-CT) after initial staging and lymph node dissection (LND). Results: PLN metastases were present in 6131 patients. Sensitivity, specificity, positive and negative predictive values (PPV, NPV) and accuracy in detecting PLN metastases were 67%, 84%, 50%, 91% and 81%, with MRI, and 33%, 92%, 50%, 85% and 81%, with FDG-PET. PALN metastases were present in 5127 patients. Sensitivity, specificity, PPV, NPV and accuracy were 60%, 73%, 33%, 89% and 70% with MRI and 100%, 77%, 50%, 100% and 81% with FDG-PET in detecting PALN metastasis. Conclusion: FDG-PET is less accurate than MRI for PLN, but more accurate for PALN; FDG-PET cannot replace PA surgical procedures, but could guide them. Source


Oluwafemi R.O.,Mother and Child Hospital | Abiodun M.T.,University of Benin
Sri Lanka Journalof Child Health | Year: 2016

Background: Preterm birth contributes significantly to neonatal deaths. Its burden should be defined to enhance interventions especially in resource-limited settings with poor neonatal health indices. Objectives: To determine the incidence of preterm delivery in the Mother and Child Hospital, Akure, to investigate the outcome and explore the relationship between birth weight and neonatal survival. Method: Demographic and clinical features (gestational age, birth weight and outcome) of consecutive preterm infants were documented for one and a half years. Incidence of preterm birth was computed, using total birth as the denominator. Quarterly incidence of preterm birth was presented graphically. Univariate logistic regression analysis of birth weight as a predictor of preterm death was done. P value < 0.05 was considered significant. Results: Of 10,432 births during study period, 1,606 were preterm giving an incidence of preterm births of 15.4%. Among preterm infants, 1,449 (90.2%) had low birth weight (LBW), 123 (7.7%) very low birth weight (VLBW) and 34 (2.1%) extremely low birth weight (ELBW). Most (92.8%) preterm babies were discharged. Prematurity had a case fatality rate (CFR) of 5.6%. Compared to normal birth weight infants, ELBW babies were 250 times and VLBW infants 47.6 times more likely to die. Conclusions: Incidence of preterm delivery in the Mother and Child Hospital, Akure was 15.4%. The CFR of prematurity was 5.6%. ELBW had the highest percentage of deaths (70.6%). Source


Akintayo A.A.,Ekiti State University, Ado Ekiti | Olagbuji B.N.,Ekiti State University, Ado Ekiti | Olagbuji B.N.,University of Cape Town | Aderoba A.K.,Mother and Child Hospital | And 3 more authors.
Maternal and Child Health Journal | Year: 2016

Objective To determine the incidence, indications and outcomes of emergency peripartum hysterectomy (EPH) in three tertiary institutions in south-west Nigeria between January, 2010 and December , 2013. Methods A retrospective review of all cases of EPH over a 4 year period was done. EPH was defined as hysterectomy performed at the time of delivery or within 24 h of delivery for uncontrollable postpartum bleeding not responsive to conservative measures. Relevant information was extracted from the hospital records and operation notes. Statistical analysis was done using SPSS software version 17.0. Statistical significance was set at p < 0.05. Results There were 102 EPHs performed among 39,738 deliveries within the study period, giving a rate of 2.6 per thousand deliveries. Indications were uterine rupture (44.1 %), uterine atony (37.3 %), morbidly adherent placenta (17.6 %) and extension of caesarean section incision involving the uterine arteries (1 %). Subtotal hysterectomy was performed in most cases (67.6 %).Maternal case fatality rate was 11.8 % and perinatal mortality rate was 55.9 %. Blood transfusion, severe postoperative anaemia, wound sepsis, febrile morbidity and acute kidney injury were common morbidities associated with the procedure. Following multivariate logistic regression, the unbooked status [odds-ratio 95 % CI = 12.80 (1.22–133.97) p = 0.03] was the only variable that significantly predicted maternal death. Conclusion The incidence of EPH from our study is high. Much more needs to be done in maternal health services, particularly provision of quality obstetric care to reduce the rates of EPH and the associated high maternal and perinatal morbidity and mortality. © 2016, Springer Science+Business Media New York. Source


Aderoba A.K.,Mother and Child Hospital | Iribhogbe O.I.,University of Benin | Olagbuji B.N.,Ekiti State University, Ado Ekiti | Olokor O.E.,University of Benin | And 2 more authors.
International Journal of Gynecology and Obstetrics | Year: 2015

Objective To determine the prevalence of helminth infestation during pregnancy and the associated risks of adverse maternal and infant outcomes. Methods A cross-sectional study of women with a singleton pregnancy of at least 34 weeks was conducted at a teaching hospital in Benin City, Nigeria, between April 1 and September 30, 2010. Socioeconomic and clinical data were obtained. Stool samples were used to determine helminth infection. Birth weight was recorded at delivery. Multivariable analysis was used to assess the link between helminth infestation and maternal and perinatal outcomes. Results Among 178 women, 31 (17.4%) had a helminth infestation (15 [8.4%] had ascariasis, 8 [4.5%] trichuriasis, and 25 [14.0%] hookworm infestation). Multivariate analysis found that helminth infestations was associated with maternal anemia (adjusted odds ratio 12.4; 95% confidence interval 4.2-36.3) and low birth weight (adjusted odds ratio 6.8; 95% confidence interval 2.1-21.9). Conclusion Approximately one in five women had a helminth infestation in the third trimester of pregnancy. Maternal helminth infestation significantly increased the risks of maternal anemia and low birth weight, indicating that routine administration of anthelminthic drugs during early pregnancy might improve perinatal outcomes. © 2015 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved. Source


Oluwafemi O.,Mother and Child Hospital | Njokanma F.,Lagos State University | Disu E.,Lagos State University | Ogunlesi T.,Olabisi Onabanjo University
SAJCH South African Journal of Child Health | Year: 2013

Background. Weight and length at birth reflect the quality of intra-uterine growth and exert a strong influence on postnatal survival. Objective. To determine the current range of anthropometric measurements of term Nigerian neonates. Methods. Consecutive term singleton mother-baby pairs were surveyed in the first 24 hours after birth. Weight, length, occipitofrontal circumference (OFC) and ponderal index were determined. Results. A total of 825 babies (440 males and 385 females) were studied. The overall mean birth weight (± standard deviation (SD)) of the study subjects was 3 233±539 g, the mean ±SD length 49.0±2.5 cm, the mean ±SD OFC 34.6±1.4 cm, and the mean ±SD ponderal index 2.7±0.4 g/cm3. Conclusion. The anthropometric parameters of the Nigerian infants studied were within the range previously reported for Africa and other developing countries, but lower than figures from some developed countries. Source

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