Moor Instruments Ltd.

Axminster, United Kingdom

Moor Instruments Ltd.

Axminster, United Kingdom
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— Growing demand for blood flow measurement devices in healthcare industry would be the major factor fostering the blood flow measurement devices market. Furthermore, rising prevalence of cardiovascular disease and diabetes coupled with increasing geriatric population, rising demand for minimally invasive surgeries, technological advancements in blood flow measurement devices, wide usage of these devices in various clinical applications, influx of VC funding, huge R&D investments by market players and increasing demand for technically advanced non-invasive devices are the factors fuelling market growth. However, stringent compliance requirements, high pricing of the devices, growing alternative methods to treat cardiovascular diseases and implementation of the Patient Protection and Affordable Healthcare Act, 2010 are limiting the market growth. Ultrasonic doppler segment is projected to witness substantial breakthrough advancements over the coming decade and is expected to provide lucrative avenues of growth. In Non-invasive applications, cardiovascular disease segment accounted for the major share whereas, Coronary Artery Bypass Grafting (CABG) devices dominated the invasive applications segment. North American region dominated the global blood flow measurement devices market with maximum revenue share due to rising prevalence of cardiovascular diseases & hypertension, increasing geriatric population, continues R&D activities for advanced products and favourable reimbursement scenario. Asia Pacific is expected to witness fastest growth on account of rapidly increasing demand for advanced healthcare technologies, increasing prevalence of cardiovascular diseases and diabetes in countries such as India and China. Some of the key players in global market include Ace Medicals, Adinstruments, ATYS Medical, Biomedix Inc, Biopac Systems Inc., Compumedics Limited, Cook Medical, Inc., Deltex Medical Group PLC, Getinge Group, Medistim ASA, Medtronics, Moor Instruments Ltd., Perimed AB, Sonotec Ultraschallsensorik Halle GmbH and Transonic Systems, Inc. Regions Covered: • North America o US o Canada o Mexico • Europe o Germany o France o Italy o UK o Spain o Rest of Europe • Asia Pacific o Japan o China o India o Australia o New Zealand o Rest of Asia Pacific • Rest of the World o Middle East o Brazil o Argentina o South Africa o Egypt What our report offers: - Market share assessments for the regional and country level segments - Market share analysis of the top industry players - Strategic recommendations for the new entrants - Market forecasts for a minimum of 6 years of all the mentioned segments, sub segments and the regional markets - Market Trends (Drivers, Constraints, Opportunities, Threats, Challenges, Investment Opportunities, and recommendations) - Strategic recommendations in key business segments based on the market estimations - Competitive landscaping mapping the key common trends - Company profiling with detailed strategies, financials, and recent developments - Supply chain trends mapping the latest technological advancements About Stratistics MRC We offer wide spectrum of research and consulting services with in-depth knowledge of different industries. We are known for customized research services, consulting services and Full Time Equivalent (FTE) services in the research world. We explore the market trends and draw our insights with valid assessments and analytical views. We use advanced techniques and tools among the quantitative and qualitative methodologies to identify the market trends. Our research reports and publications are routed to help our clients to design their business models and enhance their business growth in the competitive market scenario. We have a strong team with hand-picked consultants including project managers, implementers, industry experts, researchers, research evaluators and analysts with years of experience in delivering the complex projects. For more information, please visit: For more information, please visit

Liu H.,Moor Instruments Ltd. | Kohl-Bareis M.,University of Applied Science Koblenz | Kohl-Bareis M.,Moor Instruments GmbH | Huang X.,Moor Instruments Ltd.
Progress in Biomedical Optics and Imaging - Proceedings of SPIE | Year: 2011

We report the design of a tissue oxygen and temperature monitor. The non-invasive, fibre based device monitors tissue haemoglobin (Hb) and oxygen saturation (SO2) and is based on white-light reflectance spectroscopy.Visible light with wavelengths in the 500 - 650nm range is utilized. The spectroscopic algorithm takes into account the tissue scattering and melanin absorption for the calculation of tissue haemoglobin concentration and oxygen saturation. The monitor can probe superficial layers of tissue with a high spatial resolution (mm3) and a high temporal resolution (40 Hz). It provides an accurate measurement with the accuracy of SO2 at 2 % and high reliability with less than 2 % variation of continuous SO 2 measurement over 12 hours. It can also form a modular system when used in conjunction with a laser Doppler monitor, enabling simultaneous measurements of Hb, SO2 and blood flow. We found experimentally that the influence of the source-detector separation on the haemoglobin parameters is small. This finding is discussed by Monte Carlo simulations for the depth sensitivity profile. The influence of probe pressure and the skin pigmentation on the measurement parameters are assessed before in vivo experimental data is presented. The combination with laser Doppler flowmetry demonstrates the importance of a measurement of both the haemoglobin and the blood flow parameters for a full description of blood tissue perfusion. This is discussed in experimental data on human skin during cuff occlusion and after hyperemisation by a pharmacological cream. Strong correlation is observed between tissue oxygen (Hb and SO2) and blood flow measurements. © 2011 SPIE-OSA.

Binzoni T.,University of Geneva | Boggett D.,Moor Instruments Ltd | Van De Ville D.,University of Geneva | Van De Ville D.,Ecole Polytechnique Federale de Lausanne
Physiological Measurement | Year: 2011

Laser-Doppler flowmetry (LDF) is an outstanding tool to monitor blood flow in a continuous and non-invasive way. In this work, we study LDF at large interoptode spacing applied to a human bone model (i.e. tibia diaphysis). To that aim, we first performed an extensive set of Monte Carlo (MC) simulations for 10 and 25 mm interoptode spacing. Second, we have assembled a dedicated LDF instrumentation based on an optimized industrial avalanche photo-detector. We performed LDF experimental measurements on human muscle using well-known physiological protocols, which confirmed the reliability of our instrumentation and the relevance of the LDF algorithms tested with the MC simulations. In a second set, we repeated the measurements on human tibia diaphysis. Again, the experiments corroborate the MC simulations and demonstrate the effectiveness of LDF to monitor blood perfusion in bone. The proposed technique has great potential for non-invasive neuro-vascular studies since it will certainly help to reveal the mechanisms underlying the interaction between bone/bone marrow, the circulatory system and the nervous system. © 2011 Institute of Physics and Engineering in Medicine.

Zion Research has published a new report titled “Blood Flow Measurement Devices Market (Laser Doppler Blood Flowmeters, Electromagnetic Blood Flowmeters and Ultrasonic Doppler Blood Flowmeters) for Diabetes, Peripheral Vascular Diseases, Dermatology, Gastroenterology, Tumor Monitoring and Other Applications: Global Industry Perspective, Comprehensive Analysis, Size, Share, Growth, Segment, Trends and Forecast, 2015 – 2021”. According to the report, global demand for the blood flow measurement devices market was valued at around USD 354.2million in 2015 and is expected to generate revenue of around USD 554.3 million by end of 2021, growing at a CAGR of around 7.8% between 2016 and 2021. Blood flow measurement devices are typically used for measurement of blood flow. This rate is calculated based on the amount of blood passing through a cross section of a blood vessel per unit time. It is used to obtainvascular assessment data by the blood flow measurement devices which help physicians to maintain the equilibrium between demand and supply of tissue oxygen of patients.Blood flow measurement devices play a very vital role in detection of number of clinical vascular conditions such as peripheral vascular diseases such as diabetic macroandmicro vascular complications and arterial occlusion.Some of the different types of blood flow measurement devices include laser doppler blood flowmeters, electromagnetic blood flowmeters and ultrasonic doppler blood flowmeters. Global blood flow measurement devices market is primarily driven by rising number of target disease such as peripheral artery diseases, diabetes, etc. across the globe. Other major driving factors aregrowing geriatric population coupled along with increasing demand for non-invasive surgeries and technologically advanced devices. However, high price of these devices and stringent regulatory policies are the major restraints that may limit the growth of the market. Nonethelessincreasing clinical applications coupled along with emerging markets across the globearelikely to disclose the new avenues for blood flow measurement devices market in the near future. The blood flow measurement devices market is segmented on the basis of different products including laser doppler blood flowmeters, electromagnetic blood flowmeters, and ultrasonic doppler blood flowmeters. In 2015, ultrasonic doppler blood flow meters was the largest segment in blood flow measurement devices market and accounted for largest share of the total market. Additionally, it is expected to continue its dominance in global market over the forecast period. Diabetes, peripheral vascular diseases, dermatology, gastroenterology, tumor monitoring and others are the key application of the global blood flow measurement devices market. The peripheral vascular diseasesegment dominated the market in terms of revenue and is expected to show moderategrowth within the forecast period. Know more before buying this report @ North America, Europe, Asia-Pacific, Latin America and Middle East & Africa are key regional segments of global blood flow measurement devices market. North America is anticipated to remain the leading region over the forecast period in 2015. Demand for blood flow measurement devices was highest in Asia-Pacific. Hence, Asia Pacific is expected to be the fastest growing region in blood flow measurement devices market during the forecast period. Moreover, Middle East and Africa and Latin America are also expected to show moderate growth for this market in the years to come. Some of the key players in the blood flow measurement devices market include Cook Medical Inc., Atys Medical, Deltex Medical, ArjoHuntleigh Inc.,Elcat GmBH, Compumedics Ltd.,Moor Instruments Ltd., GF Health Products, Inc., and Transonic Systems Inc.,.Medistim ASA, and Perimed AB among others. This report segments the global blood flow measurement devices market as follows:

Al-Gayem Q.,Lancaster University | Liu H.,Moor Instruments Ltd | Richardson A.,Lancaster University | Burd N.,Lancaster University
Journal of Electronic Testing: Theory and Applications (JETTA) | Year: 2011

Electrode technology is fundamental to numerous actuation and sensing functions in bio-fluidic microsystems that target portable bio-analytical instruments. Within these systems high levels of reliability and robustness are crucial and normally complemented by requirements for extremely low probabilities of false positives or negatives being generated. New methods of validating functionality and integrity of the reading are hence required. Embedded test and condition monitoring are crucial technologies for delivering these capabilities. This paper presents two solutions for detecting degradation in electrodes that interface to fluidic or biological systems. In the first solution, a low frequency, impedance based method for identifying degraded structures within an array is proposed. This method depends on measuring and comparing the impedance of each sensing electrode. This research is backed up by physical measurements from an electrode array for drug testing on cardiac and neuron tissue. In the second solution, a mid-frequency oscillation test technique is proposed that is sensitive to degradation in the bio-fluidic interface capacitance, to contamination and to fouling. © 2010 Springer Science+Business Media, LLC.

Al-Gayem Q.,Lancaster University | Liu H.,Moor Instruments Ltd. | Richardson A.,Lancaster University | Burd N.,Lancaster University | Kumar M.,Lancaster University
Proceedings - International Test Conference | Year: 2010

This paper presents a solution for detecting degradation in electrodes that interface to fluidic or biological systems that forms the basis of numerous actuation and sensing mechanisms in the bio-fluidics field. In this solution, a mid-frequency oscillation test strategy is proposed and evaluated experimentally on an array of electrodes. This technique is based on the sensitivity of the bio-fluidic interface capacitance to degradation, contamination and fouling. © 2010 IEEE.

Kuliga K.Z.,University of Southampton | Mcdonald E.F.,University of Southampton | Gush R.,Moor Instruments Ltd. | Michel C.,Imperial College London | And 2 more authors.
Microcirculation | Year: 2014

To evaluate the dynamics of skin microvascular blood flow (BF) and tissue oxygenation parameters (OXY) measured simultaneously at the same site using a combined non-invasive BF+OXY+temperature probe. Methods: Skin BF, oxygenated (oxyHb) and deoxygenated (deoxyHb) haemoglobin and mean oxygen saturation (SO2) were measured in 50 healthy volunteers at rest and during perturbation of local blood flow by post-occlusive reactive hyperaemia, sympathetic nervous system-mediated vasoconstriction (deep inspiratory breath-hold) and local skin warming. Signals were analysed in time and frequency domains. Results: The relationship between BF and SO2 over the range of flows investigated was described by a non-linear equation with an asymptote for SO2 of 84% at BF >50 PU. SO2 was independently associated with BF, skin temperature, BMI and age, which together identified 59% of the variance in SO2 (p<0.0001). Fourier analysis revealed periodic low frequency fluctuations in both BF and SO2, attributable to endothelial (~0.01 Hz), neurogenic (~0.04 Hz) and myogenic (~0.1Hz) flow motion activity. The frequency coherence between the BF and SO2 signals was greatest in the endothelial and neurogenic frequency bands. Conclusions: The simultaneous evaluation of microvascular blood flow and oxygenation kinetics in healthy skin provides a platform from which to investigate microvascular impairment in the skin and more generally the pathogenesis of microvascular disease. © 2014 John Wiley & Sons Ltd.

Al-Gayem Q.,Lancaster University | Richardson A.,Lancaster University | Liu H.,Moor Instruments Ltd | Burd N.,Lancaster University
Journal of Electronic Testing: Theory and Applications (JETTA) | Year: 2011

There is significant interest in the use of electrodes for sensing or actuation in bio-fluidic microsystems. Within these systems high levels of reliability are crucial and complimented by requirements for extremely low probabilities of false positive and false negatives. This paper extends previous work on impedance and oscillation based condition monitoring of electrode arrays by investigating the application of oscillation built-in self-test to a microfluidic based electrodes for conductance measurements and a system level implementation for monitoring multiple electrodes on-line. © 2011 Springer Science+Business Media, LLC.

Agency: GTR | Branch: Innovate UK | Program: | Phase: Feasibility Study | Award Amount: 146.55K | Year: 2013

Reconstructive plastic surgery is in the front line for the removal of cancerous tumours of the breast, head, neck and other sites. Reconstructions following tumour removal usually require the replacement of removed tissue with tissue (i.e. skin, fat, muscle, bone) from other body sites to complete the procedure. The transferred tissues rely on an adequate blood supply to avoid complete or partial failure. The Laser Speckle Imaging technique (LSI) is a new and fast way of seeing blood flow in the skin and other tissues enabling surgeons to optimise tissue blood flow during surgery. The new LSI technique scans areas of up to 15cm x 20cm at video frame rates; larger and faster than other techniques. The purpose of this proposal is to examine the feasibility of applying the new technology for reconstructive plastic surgery. This will benefit patients by avoiding the trauma of a failing reconstruction requiring additional surgery and it will therefore reduce NHS costs.

Agency: GTR | Branch: Innovate UK | Program: | Phase: Smart - Proof of Concept | Award Amount: 97.09K | Year: 2011

The 710046 project is developing a dual tissue oxygen and skin perfusion imager.

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