Monroe College is an American for-profit college in New York State with campuses in The Bronx, New Rochelle, and Queens. It also has a campus in the Caribbean nation of Saint Lucia. The college is named after James Monroe, the fifth President of the United States.The college offers Associate and Bachelor's degrees in accounting, business, information technology, health services, law enforcement and cookery, and, through King Graduate School, four Master's programs.Students at the school are 64% female and 36% male; about 48% are of black or African-American ethnicity and about 44% of Hispanic or South American origin. Wikipedia.
Fonseca M.V.,Monroe College |
Swanson M.S.,University of Michigan
Frontiers in Cellular and Infection Microbiology | Year: 2014
The Gram-negative bacterium Legionella pneumophila is ubiquitous in freshwater environments as a free-swimming organism, resident of biofilms, or parasite of protozoa. If the bacterium is aerosolized and inhaled by a susceptible human host, it can infect alveolar macrophages and cause a severe pneumonia known as Legionnaires' disease. A sophisticated cell differentiation program equips L. pneumophila to persist in both extracellular and intracellular niches. During its life cycle, L. pneumophila alternates between at least two distinct forms: a transmissive form equipped to infect host cells and evade lysosomal degradation, and a replicative form that multiplies within a phagosomal compartment that it has retooled to its advantage. The efficient changeover between transmissive and replicative states is fundamental to L. pneumophila's fitness as an intracellular pathogen. The transmission and replication programs of L. pneumophila are governed by a number of metabolic cues that signal whether conditions are favorable for replication or instead trigger escape from a spent host. Several lines of experimental evidence gathered over the past decade establish strong links between metabolism, cellular differentiation, and virulence of L. pneumophila. Herein, we focus on current knowledge of the metabolic components employed by intracellular L. pneumophila for cell differentiation, nutrient salvaging and utilization of host factors. Specifically, we highlight the metabolic cues that are coupled to bacterial differentiation, nutrient acquisition systems, and the strategies utilized by L. pneumophila to exploit host metabolites for intracellular replication. © 2014 Fonseca and Swanson.
Thomas E.K.,State University of New York at Buffalo |
Szymanski J.,Monroe College |
Briner J.P.,State University of New York at Buffalo
Journal of Quaternary Science | Year: 2010
With accelerated melting of alpine glaciers, understanding the future state of the cryosphere is critical. Because the observational record of glacier response to climate change is short, palaeo-records of glacier change are needed. Using proglacial lake sediments, which contain continuous and datable records of past glacier activity, we investigate Holocene glacier fluctuations on northeastern Baffin Island. Basal radiocarbon ages from three lakes constrain Laurentide Ice Sheet retreat by ca. 10.5 ka. High sedimentation rates (0.03cm a -1) and continuous minerogenic sedimentation throughout the Holocene in proglacial lakes, in contrast to organic-rich sediments and low sedimentation rates (0.005cma -1) in neighbouring non-glacial lakes, suggest that glaciers may have persisted in proglacial lake catchments since regional deglaciation. The presence of varves and relatively high magnetic susceptibility from 10 to 6 ka and since 2ka in one proglacial lake suggest minimum Holocene glacier extent ca. 6-2ka. Moraine evidence and proglacial and threshold lake sediments indicate that the maximum Holocene glacier extent occurred during the Little Ice Age. The finding that glaciers likely persisted through the Holocene is surprising, given that regional proxy records reveal summer temperatures several degrees warmer than today, and may be due to shorter ablation seasons and greater accumulation-season precipitation. © 2009 John Wiley & Sons, Ltd.
Fetzner M.,Monroe College
Journal of Asynchronous Learning Network | Year: 2013
Over the past twelve years, Monroe Community College (MCC), in Rochester, NY, has administered three surveys to non-successful online students to ask about their perceptions of online learning and to learn about student perceived barriers in the online environment. For these surveys, non-successful students were defined as those students who received a grade of F or W in an MCC online course. Typically, these particular students do not share their perceptions of online learning with the college because they rarely participate in end of the year student satisfaction surveys. Thus, their perceptions are often invisible and unknown to institutions. In the MCC surveys, students were asked to: share their perspectives on why they felt that were not successful in their online class; comment on their expectations for online classes; and share the advice that they would give to a student who was considering taking an online MCC class. The students' responses to these questions were fairly consistent over the course of time that the surveys were conducted, 2000-2001, 2005-2006, and 2009-2010. The combined responses for the three surveys indicated that the number one reason why students felt that they were not successful in their online course was because they got behind and couldn't catch up. Although online student satisfaction surveys provide insights into the perceptions of online students, the voluntary respondents to these surveys are those students who typically did well in the course. A review of the results of the responses from unsuccessful online students broadens the scope of the voice of the students and brings to the forefront the perspectives of students who were not successful. These data can help to inform the types of student services support that unsuccessful online MCC students feel are needed.
Wang J.,Monroe College |
Liu X.,Eli Lilly and Company |
Mullins C.D.,University of Maryland, Baltimore
Current Medical Research and Opinion | Year: 2011
Objective: Chronic pain is prevalent in patients with major depressive disorder (MDD). This study compared adherence and persistence rates among MDD patients with comorbid chronic pain-related diseases (CPD, including fibromyalgia, diabetes with neurological manifestations, osteoarthritis, low back pain, and headache) for three antidepressants: duloxetine, venlafaxine XR, and escitalopram. Research design and methods: A retrospective analysis was conducted of 15,523 adult MDD patients with CPD in the MarketScan Commercial Claims and Encounters Database who started on one of the study medications between 07/01/06 and 06/30/07. Patients were followed-up for 6 months. Adherence was reported using a medication possession ratio ≥0.8. Persistence was measured using persistence rates (proportions of patients who continuously refilled prescriptions during 6 months) and duration of therapy (number of days patients remained on the study medication before a prescription gap over 30 days). Multivariate logistic regression on adherence and persistence rates and linear regression on duration of therapy adjusting for patient and prescription characteristics were conducted. Results: Patients on duloxetine had a higher adherence rate (46.03%) than those on venlafaxine XR (42.94%; p=0.0033) or escitalopram (37.27%; p<0.0001). Patients on duloxetine also had a higher persistence rate and longer duration of therapy (43.66%, 117.82 days) than did patients treated with venlafaxine XR (40.38%; p=0.0017; 114.24 days; p=0.009) or escitalopram (33.86%; p<0.0001; 105.73 days; p<0.0001). These differences were still significant after adjusting for patient and prescription characteristics (p<0.05). Sensitivity analyses found similar patterns using an allowable gap for refill of 15 days. Conclusions: Among commercially insured MDD patients with CPD, duloxetine-treated patients had higher adherence and persistence rates than did patients treated with venlafaxine XR or escitalopram during 6 months after medication initiation. Future studies should examine the clinical and economic implications of these differences. Limitations: This study has limitations such as possible selection bias using secondary database analysis. © 2011 Informa UK Ltd.
Wojtczak J.,University of Rochester |
Bonadonna P.,Monroe College
American Journal of Emergency Medicine | Year: 2013
Background: Focused ultrasonography of the airway may be useful in the prediction of difficult intubation. The wider use of sonography in quantitative airway assessment may depend on the availability of highly portable, inexpensive, and accurate ultrasound systems. Pocket-sized ultrasound devices are emerging as a useful tool for point-of-care ultrasonography. The aim of this study was to evaluate the suprahyoid airway of healthy volunteers using a smartphone-based ultrasound imaging system in comparison with a platform-based machine. Methods: Mobisante MobiUS SP1 system with 2 mechanical sector (3.5 and 7.5 MHz) probes was used to acquire images of the tongue and measure the diameter of the hyomental muscle in the mouth floor. In the same group of subjects, imaging and measurements were repeated using BK Medical Flex Focus 400 ultrasound system with linear (18 MHz) and curved 5 (MHz) transducers. The MobiUS system was also used to image plastic cylinders and procedure needles embedded in tofu bars. Outside diameters of cylinders were measured using digital calipers and sonography. Results: The mean diameter of the hyomental muscle in 10 healthy volunteers was 7.22 ± 1.6 mm using BK 18 MHz probe, 7.11 ± 1.7 mm using MobiUS 7.5 MHz probe, and 7.84 ± 2 mm using MobiUS 3.5 MHz probe. These means were not statistically different (BK vs Mo 7.5, P =.74, and BK vs Mo 3.5, P =.13). The mean outside diameter of plastic cylinders measured with digital calipers was 10.1 ± 0.2 mm (n = 5) vs 9.8 ± 0.3 mm and 10.2 ± 0.2 mm using 3.5 and 7.5 MHz probes, respectively. These means were not statistically different (calipers vs Mo 3.5, P =.16 and calipers vs Mo 7.5, P =.39). Conclusion: Mobisante MobiUS system was able to acquire clinically useful images of the suprahyoid airway and muscular architecture in the mouth floor and allowed accurate measurements of linear distances. © 2013 Elsevier Inc. All rights reserved.