Grand Rapids, MI, United States
Grand Rapids, MI, United States
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Methods and systems for use in sperm analysis are described. A method for processing measured data comprising at least interferometric phase data of label-free sperm cell(s), the processing comprising determining topographic optical phase delay map of the label-free sperm, determining at least one physical parameter of the label-free sperm, and generating data indicative of sperm quality for the label-free sperm. A device comprising a flow channel comprising an inlet for receiving fluid containing cells, a selection zone and at least two outlets at said selection zone; and a flow-driving mechanism comprising a flow-driving unit configured and operable to generate flow of said fluid from said inlet towards at least first of said at least two outlets, and a collecting driving unit selectively operating along the direction of a second outlet of said at least two outlets to direct a portion of interest of said fluid towards said second outlet.

Momentum | Date: 2015-10-28

Energetic nitrogen-rich monomers represented by the general Formula I: wherein each of X1 and X2 is independently NR or a covalent bond. R is H or C1-4 alkyl, each of T1 and T2 is independently a moiety selected from the group consisting of a triazole moiety, a tetrazole moiety and a guanidine moiety, at least one of T1 and T2 being substituted by at least one polymerizable group, are disclosed herein, as well as polymers based thereon, and uses of such polymers.

The invention relates to a drive system, in particular for applications in conveying technology and in the food industry, comprising: a stationary shaft (1), an electric motor (2), which has a rotor (3) that can be rotated around the shaft (1) and a stator (6); a transmission (16) for reducing a rotational speed of the rotor (3); and a drum (13), which can be driven by the transmission (16) at a reduced rotational speed and can be rotated concentrically around the shaft. The rotor (3) and the transmission (16) are arranged inside the drum (13). The stator (6) of the electric motor (2) is arranged outside the drum (13). The stator (6) preferably surrounds the drum (13) completely or partially, specifically substantially in the region (B) in which the rotor (3) is arranged inside the drum (13). It can also be advantageous for the stator (6) to only partially surround the drum (13), in particular to surround only 180 or less of the outer circumference (15) of the drum (13) in the form of a half shell (25). The invention allows for the transmission of large torque to a rotatable drum at relatively low rotational speed, despite low space requirement, and requires no electrical supply lines to rotating parts or electrical feed-throughs in spaces having lubricants. This allows for the invention to be used in particular for conveying systems and especially in the food industry in cases in which there are heightened requirements for hygiene and cleanliness.

Momentum | Date: 2015-03-31

The present invention relates to a drive system, in particular for applications in conveying technology and the food industry, having a fixed shaft (1), having an electric motor (2) which has a rotor (3), which can be rotated about the shaft (1), and a stator (6), having a transmission (16) for reducing a rotational speed of the rotor (3), and having a drum (13) which can be driven by the transmission (16) at a reduced rotational speed and can be rotated concentrically about the shaft, wherein the rotor (3) and the transmission (16) are arranged within the drum (13), and wherein the stator (6) of the electric motor (2) is arranged outside the drum (13). The stator (6) preferably wholly or partially encloses the drum (13), to be precise essentially in the region (B), in which, within the drum (13), the rotor (3) is arranged. It may also be advantageous if the stator (6) only partially encloses the drum (13), in particular, in the form of a half-shell (25), encompasses only 180 or less of the outer circumference (15) of the drum (13). The invention allows, despite only a small amount of space being required, to transmit large torques, at a relatively low rotational speed, to a rotatable drum and does not require any electrical supply lines to rotating parts or electric feed-throughs in spaces with lubricants. This allows the invention to be used, in particular, in conveying systems and, quite particularly, in the food industry where stringent requirements in respect of hygiene and cleanliness have to be met.

Momentum | Date: 2017-02-01

The invention provides methods and formulations for imaging at least one body region of a subject, employing a glucose analog resistant or inactive to phosphrylation, or which is not a substrate for hexokinase. In a preferred embodiment, the glucose analog is 3-O-methylglucose and the imaging technique is chemical exchange saturation transfer (CEST) MRI.

Quarks cannot be observed as free particles in nature because they are confined into baryons and mesons, as a result of the fact that the strong interaction between them increases with their separation. However, it is less known that this phenomenon also occurs in condensed matter and statistical physics as experimentally proved in several quasi-1D compounds. Most of the theoretical and experimental studies so far concentrated on understanding the consequences of confinement for the equilibrium physics of both high-energy and condensed matter systems. Here, instead we show that confinement has dramatic consequences for the non-equilibrium dynamics following a quantum quench and that these effects could be exploited as a quantitative probe of confinement. © 2016 Nature Publishing Group

Agency: European Commission | Branch: H2020 | Program: IA | Phase: BIOTEC-3-2014 | Award Amount: 9.25M | Year: 2015

C-C bond forming reactions are at the heart of industrial organic synthesis, but remain largely unexplored due to long development timelines and the lack of broad biocatalytic reaction platforms. CARBAZYMES addresses these challenges by assembling an interdisciplinary and intersectoral consortium as a powerful synergistic tool to promote innovation in the field of biocatalytic C-C bond formation at large scale, and thus the global competitiveness of the European chemical and pharmaceutical industry. The proposed consortium, with 50% industrial participation, represents academia but also commercial interests in different stages of the research-to-market process. This top-down approach, together with a life-cycle innovation approach ensures an industrial drive to the project. Clearly aligned with the scope of topic BIOTEC3-2014, CARBAZYMES will pursue the biocatalytic synthesis (spanning TRLs 5-7) of 4 APIs and 3 bulk chemicals corresponding to market needs detected by the industrial partners in the Consortium. This will be accomplished through an inter-disciplinary approach which includes: i) a broad platform of 4 types of unique C-C bond-forming enzymes, mostly lyases; ii) the capacity to rapidly evolve enzymes to operate under industrial conditions by means of novel enzyme panels and massive screening methods; iii) application of microreactor technology for bioprocess characterization; iv) demonstration actions comprising technical (up to 100L) and economic viability studies carried out by industrial partners. CARBAZYMES unmistakably aims to have social and economic impact by addressing markets worth bn , developing enzyme evolution technologies beyond the state of the art and creating qualified jobs and technical-scale facilities at the industrial partners sites. CARBAZYMES will also achieve an environmental impact by enforcing that the developed processes replace more energy and resource intensive processes, thus leading to reduced environmental footprints.

An energy dissipator for use in a sumped manhole includes a sheet member. The sheet member defines a downstream surface, an upstream surface opposite the downstream surface, and opposing side edges each extending between the downstream surface and the upstream surface. The sheet member includes a plurality of apertures. Each of the plurality of apertures extends through both the downstream surface and the upstream surface. The sheet member extends in an arcuate manner between the opposing side edges. The dissipator is configured to intercept fluid flow within the manhole to decrease energy and control flow dynamics within the manhole.

A substrate structure is provided for use in a superconductive device. The substrate structure has at least one of its two opposite surfaces configured for carrying at least one superconductive structure thereon. The substrate structure comprises a substrate made of a dielectric material composition and having a tape-like shape of a predetermined geometry characterized by a width-thickness aspect ratio of at least 10 and global planarity of said at least one surface defined by a surface roughness on a nanometric scale substantially not exceeding 1 nm rms.

Hybrid hydrogels formed of a plurality of peptides that are capable of self-assembling into a hydrogel in an aqueous solution and a biocompatible polymer that is characterized by high swelling capability, high elasticity and low mechanical strength are disclosed, with exemplary hybrid hydrogels being formed of a plurality of aromatic dipeptides and hyaluronic acid. The hybrid hydrogels are characterized by controllable mechanical and biological properties which can be adjusted by controlling the concentration ratio of the peptides and the polymer, and which average the mechanical and biological properties of the peptides and the polymer. Processes of preparing the hydrogels and uses thereof in pharmaceutical, cosmetic or cosmeceutic applications such as tissue engineering and/or regeneration are further disclosed.

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