Singleton C.,Momenta Pharmaceuticals Inc.
Bioanalysis | Year: 2012
Sample preparation has historically been, and continues to be, the most challenging part of the bioanalytical workflow. Several techniques have been developed over the years to deal with the problems of recovery and matrix effects in an effort to increase the reliability and robustness of the bioanalytical method. In recent years certain techniques have come into prominence and gained acceptance in routine sample preparation, and some have shown promise in their use in a discovery environment where speed is critical and method development time is often limited. The aim of this review is to examine several of these techniques and provide examples of their use from the literature, as well as comment on their utility in current workflows. © 2012 Future Science Ltd.
Momenta Pharmaceuticals Inc. | Date: 2015-09-09
The present invention provides methods of evaluating a glycoprotein preparation for the absence, presence or amount of an N-acetylhexosamine glycan, e.g., an N-acetylglucosamine glycan.
Momenta Pharmaceuticals Inc. | Date: 2015-10-14
The invention provides methods, databases and systems for making glycoprotein products having defined properties.
Momenta Pharmaceuticals Inc. | Date: 2015-08-21
Momenta Pharmaceuticals Inc. | Date: 2015-11-13
Methods for analyzing, selecting, characterizing or classifying compositions of a co-polymer, e.g., glatiramer acetate are described. The methods entail analysis of pyro-glutamate in the composition, and, in some methods, comparing the amount of pyro-glutamate present in a composition to a reference standard.