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Daejeon, South Korea

Yoon M.,Mokwon University
PPAR Research | Year: 2010

Peroxisome proliferator-activated receptor (PPAR ) is a member of the steroid hormone receptor superfamily and is well known to act as the molecular target for lipid-lowering drugs of the fibrate family. At the molecular level, PPAR regulates the transcription of a number of genes critical for lipid and lipoprotein metabolism. PPAR activators are further shown to reduce body weight gain and adiposity, at least in part, due to the increase of hepatic fatty acid oxidation and the decrease in levels of circulating triglycerides responsible for adipose cell hypertrophy and hyperplasia. However, these effects of the PPAR ligand fenofibrate on obesity are regulated with sexual dimorphism and seem to be influenced by the presence of functioning ovaries, suggesting the involvement of ovarian steroids in the control of obesity by PPAR . In female ovariectomized mice, 17 -estradiol inhibits the actions of fenofibrate on obesity through its suppressive effects on the expression of PPAR target genes, and these processes may be mediated by inhibiting the coactivator recruitment of PPAR . Thus, it is likely that PPAR functions on obesity may be enhanced in estrogen-deficient states. Copyright © 2010 Michung Yoon. Source

Soak S.-M.,Information Examination Team | Lee S.-W.,Mokwon University
Applied Intelligence | Year: 2012

In this paper, we propose a new memetic algorithm for the quadratic multiple container packing problem. The proposed memetic algorithm is based on the adaptive link adjustment evolutionary algorithm (ALA-EA) and it incorporates heuristic fitness improvement schemes into the ALA-EA. In addition, we propose a new powerful initialization method for the QMCPP. The proposed algorithm is compared to the previous approaches. We report that it can find much improved final solutions at most benchmark instances. Moreover, even the best solutions of the first generation show better than the previous known best solutions at most of instances especially with density d=0.75. In addition, we compare the proposed memetic algorithm to the NetKey based evolutionary algorithm for analyzing features of the ALA-EA. © 2010 Springer Science+Business Media, LLC. Source

Kim J.T.,Mokwon University
International Journal of Security and its Applications | Year: 2014

Wireless sensor network is widespread used in hospital environment with mobile device such as NFC, RFID tag and small sensor nodes. The use of a mobile agent in healthcare system under wireless network environment gives an opportunity to offer better services for patients and staffs such as doctors and nurses because of its mobility. But, optimized security protocols and schemes between sensor and patient device are essential for high performance and security problem in U-healthcare system. But a lot of threats, attacks and vulnerability are induced because of limited resources such as small memory and low computation capability in wireless sensor network. The characteristics of U-healthcare systems are analyzed to solve security issues in this paper. © 2014 SERSC. Source

Oh S.-H.,Mokwon University
Neurocomputing | Year: 2011

Classification of imbalanced data is pervasive but it is a difficult problem to solve. In order to improve the classification of imbalanced data, this letter proposes a new error function for the error back-propagation algorithm of multilayer perceptrons. The error function intensifies weight-updating for the minority class and weakens weight-updating for the majority class. We verify the effectiveness of the proposed method through simulations on mammography and thyroid data sets. © 2010 Elsevier B.V. Source

Cho Y.H.,Mokwon University
Progress in Electromagnetics Research Letters | Year: 2012

An infinitely flanged coaxial line is analytically solved with the mode-matching technique and Green's function to propose a precise yet fast-convergent scattering solution for complex permittivity measurement. Based on virtual current cancelation, we formulate the open half-space fields in terms of coaxial modes and related Green's functions and thus obtain the simultaneous equations with rapidly convergent integrals. Numerical computations were performed in terms of reflection coeffcients and radiation patterns. Source

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