Cambridge, MA, United States

Moderna Therapeutics

www.modernatx.com
Cambridge, MA, United States

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Patent
Moderna Therapeutics | Date: 2016-09-15

Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to kill or reduce the growth of microorganisms. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent microbial infection, or to improve a subjects heath or wellbeing.


Patent
Moderna Therapeutics | Date: 2016-01-04

The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them.


Patent
Moderna Therapeutics | Date: 2016-08-26

Provided are compositions and methods for delivering biological moieties such as modified nucleic acids into cells to modulate protein expression. Such compositions and methods include the use of modified messenger RNAs, and are useful to treat or prevent diseases, disorders or conditions, or to improve a subjects heath or wellbeing.


Patent
Moderna Therapeutics | Date: 2017-04-26

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.


Patent
Moderna Therapeutics | Date: 2017-05-24

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of chimeric polynucleotide molecules, which allow for customized placement, position and percent load of chemical modifications, which improve, alter or optimize certain physicochemical and pharmaceutical properties of the polynucleotides. In one non-limiting embodiment, such chimeric polynucleotides take the form or function as modified mRNA molecules which encode a polypeptide of interest. In one embodiment, such chimeric polynucleotides are substantially noncoding.


Patent
Moderna Therapeutics | Date: 2015-06-19

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.


Patent
Moderna Therapeutics | Date: 2017-04-26

The present disclosure provides alternative nucleosides, nucleotides, and nucleic acids, and methods of using them.


Patent
Moderna Therapeutics | Date: 2017-05-24

The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of circular polynucleotides.


Patent
Moderna Therapeutics | Date: 2017-07-12

The invention relates to tolerogenic compositions and methods for the preparation, manufacture and therapeutic use thereof.


Patent
Moderna Therapeutics | Date: 2016-08-17

The present disclosure provides modified nucleosides, nucleotides, and nucleic acids, and methods of using them.

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