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Amane H.S.,SDM Medical College and Hospital | Burte N.P.,Mnr Medical College
Indian Journal of Pharmacology | Year: 2011

Objective: To compare the efficacy and safety profile of dalteparin, a low-molecular-weight heparin with a standard unfractionated heparin in patients with unstable angina pectoris. Materials and Methods: This was a 6-month, prospective, parallel, randomized and open-labeled study. Patients of angina pectoris were randomized to receive either unfractionated heparin or dalteparin for 5 days. They were followed for 21 days during three visits on 1 st, 5 th and 21 st days. A series of resting electrocardiogram were undertaken in all patients on each visit. Results: The frequency of the combined clinical outcome of death, myocardial infarction and recurrence of angina was similar during 21 days of follow-up with either dalteparin or intravenous unfractionated heparin. In patients who received dalteparin 2.43% patients developed minor bleeding in the form of epistaxis and 2.5% patients who received unfractionated heparin developed minor bleeding in the form of macroscopic hematuria. Conclusion: Dalteparin is as effective and safe as unfractionated heparin in the treatment of unstable angina. Dalteparin does not require routine laboratory monitoring as with unfractionated heparin.


Mukhopadhyay B.K.,MNR Medical College
World Journal of Laparoscopic Surgery | Year: 2012

Laparoscopic surgery is a less painful surgery to patients but is more for the doctor. Surgeons feels fatigue and discomfort due to its technical complexity and ergonomics. Prolong duration of surgery and pneumoperitoneum creates the patient exhausted and causes some remarkable hemodynamic changes. During operation the strategic rest break after 90 minutes, for 5 minutes, increase the better outcome not only to patients but also to the doctor.


Patil T.B.,MNR Medical College | Paithankar M.M.,Government Medical College
Annals of Tropical Medicine and Public Health | Year: 2012

Aims: This study was aimed to study the clinical and radiological profile of neurocysticercosis and outcomes of treatment in neurocysticercosis. Settings and Design: A prospective observational study in a tertiary care hospital. Methods and Material: A total of 40 patients coming under definitive or probable diagnosis of neurocysticercosis as per the revised diagnostic criteria for neurocysticercosis were included in this study. Clinical history, physical examination, and neuroimaging (CT or MRI) studies were done at the beginning. Patients were treated with albendazole, corticosteroids, and antiepileptic drugs. They were followed up clinically for 3 months and neuroimaging study was repeated 3 months after albendazole therapy. Results: Definitive cases were 28 (70%) and probable cases were 12 (30%). Male: female ratio was 2.07. Mean age of 29.62 9.08 years. The commonest presentation was seizures in 38 (95%). Twenty-nine (72.5%) patients had a single lesion and 11 (27.5%) had multiple lesions in initial imaging study. Commonest site of lesion was parietal lobe (45%). Most common stage of presentation was colloidal (55%). Thirty-seven (92.5%) patients were free of seizures at the end of three months. At the end of 3 months, 23 (57.5%) patients had radiological resolution (Complete resolution + partial resolution + calcification). Conclusions: Neurocysticercosis usually affects young persons, mostly in third decade, being equally common among vegetarians. Most common clinical manifestation is seizures. Single lesion is more common than multiple lesions, commonly presenting in colloidal. Clinical and radiological response to 4-week therapy with albendazole is quite satisfactory. All cases of young-and adult-onset epilepsy in tropical countries should be investigated for neurocysticercosis.


A study was conducted to assess the visual outcomes of patients after cataract surgery with intraocular lens implants with reference to visual acuity (VA) and visual function (VF) and to assess patient satisfaction with surgical outcome. The retrospective study was carried out using operation theatre records at the Rural Health Training Centre (RHTC), Paithan, during 2007. Out of 819 cataract surgery patients operated in 2007 a total of 50 were selected randomly. Door-to-door visits were paid by investigator and multipurpose worker to previously operated patients for VA examination and to fill predesigned questionnaire. Statistical analysis was done by using SPSS 17.0 Version; 50% patients had VA in fair vision range of <6/18-6/60 and 52% showed the VF in the range of 76-100. Of the 32 satisfied patients, majority were in the age group 70-79 years. The patients with good visual outcomes achieved after surgery would act as pamphlets for the community.


Mohammad A.,MNR Medical College | Nagaiah G.,MNR Medical College | Akshay S.,MNR Medical College | Jitendra,MNR Medical College
Indian Journal of Community Health | Year: 2015

Introduction: Micronutrients play a very important role in both promoting health and curing disease by health professionals. They play a central part in metabolism and in the maintenance of tissue function. It is important that doctors and other health professionals are aware of the evidence for the nutritional essentiality of these substances, and for the situations where an increased intake may lead to clinical benefit. Objectives: 1. To assess the knowledge of health professionals micronutrients and practices in prescribing in treatment. 2. To determine the measures followed by the health professionals in including micronutrients in their own diet. Materials and Methods: A pre-designed and pre-tested anonymous self administered questionnaire was used in a cross sectional study. Results: 70% of doctors said that they had enough knowledge about prescribing and counseling to patients regarding micronutrients. On comparing the knowledge of specialists about micronutrients with the general practitioners we didn’t find any significant increase in knowledge with specialization. A large section of doctors 95% of agreed that nutrition plays an important role in treatment and prescription and counseling of micronutrients is needed. But 82% of doctors are not sure and 8% even strongly disagreed if their patients will follow a diet plan even if given. Most of the study participants felt they were not up-to-date about micronutrients. Majority of them attributed this to lack of time and being unaware of any structured resource. Conclusion There is a need to restructure about imparting micronutrients education among doctors. Greater efforts should be aimed towards imparting updates about micronutrients in doctors and other health professionals enable them to contribute positively towards a healthy society. More Studies should be carried out in healthcare professionals. © 2015, Indian Association of Preventive and Social Medicine. All rights reserved.


Gurulingappa,MRMC | Aleem M.A.,MNR Medical College | Awati M.N.,MRMC | Adarsh S.,MRMC
Journal of Clinical and Diagnostic Research | Year: 2012

Background and objectives: Laryngoscopy and tracheal intubation is invariably associated with a reflex sympathetic pressor response resulting in elevated heart rate and blood pressures. This may prove detrimental in high risk patients. Objective of this study is to compare the effects of lignocaine and fentanyl in attenuation of this pressor response to laryngoscopy and tracheal intubation. Methods: Seventy five ASA I and II status normotensive patients scheduled for elective surgical procedures were selected randomly and divided into three groups of 25 each. All patients received premedication with pentazocine 0.05mg/kg i.v., atropine 0.01mg/ kg intramuscularly and midazolam 0.01mg/kg i.v. half an hour prior to induction. Induction of anesthesia was standardized for all patients who received, thiopentone 5 mg/kg i.v. and and were relaxed with succinylcholine 2mg/kg i.v. The first group received fentanyl 4micrograms/kg i.v bolus, the second group received lignocaine 1.5mg i.v bolus and then third group received placebo (normal saline), 5 minutes before laryngoscopy and intubation. HR, systolic, diastolic blood pressure were recorded noninvasively one day priorly B, Before induction 0 postinduction, 1,2,3,4 and 5 minutes from the onset of laryngoscopy. Results: After intubation incidence of tachycardia (HR>100/min) was significantly greater in placebo and lignocaine group than in fentanyl group (p<0.05). Rise in SBP and DBP were also statistically significant in placebo and lignocaine group than in fentanyl group (p<0.05). Conclusion: Attenuation of pressor response is seen both with lignocaine and fentanyl. Of the two drugs fentanyl 4mgicrogram i.v. bolus provides a consistent, reliable and effective attenuation as compared to lignocaine 1.5mg/kg iv. bolus.


Mukhopadhyay B.K.,MNR Medical College
World Journal of Laparoscopic Surgery | Year: 2013

Knots are very important in the general and laparoscopic surgery. Knots are of two types, extracorporeal and intracorporeal. Intracorporeal knots are difficult while extracorporeal knots are comparatively easy to make, as we make it outside. This new knot (Dilip-Sarbani knot) is an extracorporeal knot. We shall take 20 cm length suture material of prolene, vicryl or catgut. Then we shall take three simple rounds in left index finger. Then we shall mark it as no 1, 2 and 3. Then we shall take no 1 over no 2 and again no 2 over no 3 and lastly no 3 over no 1. Then we shall pull it tightly. The knot is prepared. Finally push the above portion of knot to the target organ for making it tight. If we want to be more secure then we can give one more simple knot. This knot can be used in tubal ligation, in appendectomy or where tubular structure and stump ligation.


Suguna D.,Mnr Medical College | Madhavi L.H.,Mnr Medical College | Nagaiah G.,Mnr Medical College
Indian Journal of Public Health Research and Development | Year: 2015

Context: An outbreak of gastro-enteritis occurred at Dubbaka village, Nizamabad District, Andhra Pradesh State, India. Aims: To investigate the gastro-enteritis out-break; identify the agent, source, mode of disease transmission and recommend control measures. Settings and Design: Cross-sectional study Method and Material: An outbreak investigation was carried out at Dubbaka village, Nizamabad District, Andhra Pradesh state, India during 16th to 23rd October 2010. Pre-tested, Pre-designed epidemiological case sheets were used. Ten stool and water samples were collected for laboratory analysis. Statistical analysis used: Chi-square test Results: Out of 3051 population, 471 cases were identified. Over-all attack rate was 15.43%, higher among above 14 yrs (20.32%) of age than in below 14yrs (8.1%), higher in females (16.17%) than in males (14.75%). The samples of stools and drinking water were positive for Escherichia coli. Conclusions: The present out-break was caused by contamination of drinking water. The quality of drinking water should be improved using locally available appropriate technology and resources. Solar water disinfection is a low cost method of purifying water that can often be implemented with locally available materials. © 2015, Indian Journal of Public Health Research & Development. All rights reserved.


PubMed | MNR Medical College
Type: Journal Article | Journal: Diabetes & metabolic syndrome | Year: 2012

Reports of urban based studies suggest an increase in the prevalence of MS worldwide along with diabetes, hypertension and atherogenic dyslipidemia. The supporting rural based studies on MS are few and prevalence of MS among women is underestimated. In this prospective study we have evaluated the clinic prevalence of metabolic syndrome among rural Indian population with special emphasis on prevalence in women.2329 patients attending to diabetic centre were evaluated for the markers of MS. Anthropometric measurements, clinical assessment, capillary blood glucose and lipid profile (TC, HDL-C, TG, LDL-C, VLDL-C) were done and classified as per NCEP ATP III and NCEP ATP III modified for Asian guidelines. We compared the prevalence of MS between males and females for statistical significance by SPSS 16.0 statistical software. The level of significance was kept at <0.05.The Clinic prevalence of metabolic syndrome was 61.74% with 57.59% males and 69.66% females as per NCEP ATP III guidelines. 73.85% of the study population had MS, with 68.85% males and 83.39% females had MS as per modified Asian criteria. We could get a statistically significant variation between males and females in FBS, PPBS, SBP, DBP, TC, HDL-C, TG, LDL-C, VLDL-C, TC/HDL, LDL/HDL, BMI, W/H ratio and W/S ratio.Prevalence MS is increasing at an epidemic proportion bringing with it micro and macro vascular complications. Women are more prone to develop MS in rural population than the men and there is a statistically significant variation in the biochemical and anthropometric parameters. This is an era of gender equality; here we see women over taking men in metabolic syndrome and its complications.


PubMed | MNR Medical College
Type: | Journal: Case reports in pediatrics | Year: 2012

Prune belly syndrome is a rare congenital disorder of the urinary system, characterized by a triad of abnormalities. The aetiology is not known. Many infants are either stillborn or die within the first few weeks of life from severe lung or kidney problems, or a combination of congenital anomalies.

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