Miyagi University of Education, or MUE is a national university at Sendai, Miyagi, Japan. The predecessor of the school was founded in 1873, and it was chartered as a university in 1965. It is accredited by the Japanese Ministry of Education, as a public co-educational institute and is ranked in Japan's first tier of leading schools. With four academic divisions, MUE offers not only degrees in Education, but also in the disciplines of Language and Social Science, Science, Math and Life, and Art and Physical Education. Their Development and Education division covers Pre-School, Children and Culture, Pedagogy, and Educational Psychology. There are specific academic tracks for Elementary, Secondary, and Special Needs Education, and many of Miyagi University of Education’s graduates go on to become Principals at schools throughout Japan. Wikipedia.
Hashimoto J.,Miyagi University of Education
Journal of Hypertension | Year: 2017
OBJECTIVE:: Stiffening of the aorta often precedes coronary events, but little is known about the aetiological mechanism. We hypothesized that the predisposition to myocardial ischemia could be attributable to aortosclerosis-induced alterations in the central haemodynamics during diastole. METHODS:: Using noninvasive tonometry and ultrasonography, we investigated the arterial pressure pulse waveforms, pulse wave velocities (PWVs) and compliance in 222 patients with hypertension. The diastolic pressure decay was quantified by fitting a mono-exponential curve as P(t)?= ?P0e [λ: decay index; P0: end-systolic pressure; t: time from end-systole]. The myocardial oxygen supply/demand balance was estimated from the subendocardial viability index (SVI). RESULTS:: The aortic pressure decay fit to an exponential curve significantly (R?=?0.98?±?0.02) and more closely than the radial pressure decay (P?0.001). The aortic decay index (median, 0.59?s) was associated with the aortic PWV and compliance (but not with the peripheral PWV or resistance), even after controlling for age, sex, renal function, diabetes and hypercholesterolemia (P?0.001). Also, both the aortic PWV and compliance (together with the augmentation index) were related to the SVI, although these relationships were no longer significant after accounting for the decay index. Mediation analysis revealed substantial mediating effects of the decay index on the relationship between aortic PWV or compliance and SVI (75–100%), despite the lack of similar effects of the augmentation index. CONCLUSION:: Aortic stiffening with reduced compliance potentially impairs myocardial viability by accelerating the diastolic exponential decay (rather than through enhancing late-systolic augmentation) of the central blood pressure, thus predisposing hypertensive patients to ischemic heart disease. Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved.
Fukuda Y.,Miyagi University of Education
Journal of Physics: Conference Series | Year: 2016
A liquid scintillator containing a tetrakis (isopropyl acetoacetato) zirconium has been developed for new project of neutrinoless double beta decay experiment (ZICOS experiment). We have synthesized a tetrakis (isopropyl acetoacetato) zirconium, which have high solubility (over 31.2 wt.%) in anisole. We measured the performance of liquid scintillator containing 10 wt.% concentration of a tetrakis (isopropyl acetoacetato) zirconium, and obtained 48.7 ± 7.1% of the light yield of BC505 and the energy resolution of 4.1 ± 0.6% at 3.35 MeV assuming 40% photo coverage of the photomultiplier, respectively. We also estimated that ZICOS experiment should be sensitive to (mν) < 0.1 eV assuming gA = 1.25, gpp = 1.11 and QRPA model, if a radius of the inner detector is 1.5 m and the detector is filled with this liquid scintillator with an enriched 96Zr nucleus and we can reduce 208 Tl backgrounds to be one tenth order of magnitude of KamLAND-Zen using Cherenkov lights.
Hashimoto J.,Miyagi University of Education
Journal of Atherosclerosis and Thrombosis | Year: 2017
Arteriosclerosis, particularly aortosclerosis, is the most critical risk factor associated with cardiovascular, cerebrovascular, and renal diseases. The pulsatile hemodynamics in the central aorta consists of blood pressure, flow, and stiffness and substantially differs from the peripheral hemodynamics in muscular arteries. Arteriosclerotic changes with age appear earlier in the elastic aorta, and age-depen-dent increases in central pulse pressure are more marked than those apparent from brachial pressure measurement. Central pressure can be affected by lifestyle habits, metabolic disorders, and endocrine and inflammatory diseases in a manner different from brachial pressure. Central pulse pressure widening due to aortic stiffening increases left ventricular afterload in systole and reduces coronary artery flow in diastole, predisposing aortosclerotic patients to myocardial hypertrophy and ischemia. The widened pulse pressure is also transmitted deep into low-impedance organs such as the brain and kidney, causing microvascular damage responsible for lacunar stroke and albuminuria. In addition, aortic stiffening increases aortic blood flow reversal, which can lead to retrograde embolic stroke and renal function deterioration. Central pressure has been shown to predict cardiovascular events in most previous studies and potentially serves as a surrogate marker for intervention. Quantitative and comprehensive evaluation of central hemodynamics is now available through various noninvasive pressure/flow measurement modalities. This review will focus on the clinical usefulness and mechanistic rationale of central hemodynamic measurements for cardiovascular risk management. © 2017 Japan Atherosclerosis Society.
Fukuda Y.,Miyagi University of Education |
Moriyama S.,University of Tokyo |
Ogawa I.,University of Fukui
Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment | Year: 2013
An organic liquid scintillator containing a zirconium complex has been developed for a new neutrinoless double beta decay experiment. In order to produce a detector that has good energy resolution (4% at 2.5 MeV) and low background (0.1counts/(t·year)) and that can monitor tons of target isotope, we chose a zirconium β-diketone complex having high solubility (over 10 wt%) in anisole. However, the absorption peak of the diketone ligand overlaps with the luminescence of anisole. Therefore, the light yield of the liquid scintillator decreases in proportion to the concentration of the complex. To avoid this problem, we synthesized a β-keto ester complex introducing -OC3H7 or -OC2H5 substituent groups in the β-diketone ligand, which shifted the absorption peak to around 245 nm, which is shorter than the emission peak of anisole (275 nm). However, the shift of the absorption peak depends on the polarity of the scintillation solvent. Therefore we must choose a low polarity solvent for the liquid scintillator. We also synthesized a Zr-ODZ complex, which has a high quantum yield (30%) and good emission wavelength (425 nm) with a solubility 5 wt% in benzonitrile. However, the absorption peak of the Zr-ODZ complex was around 240 nm. Therefore, it is better to use the scintillation solvent which has shorter luminescence wavelength than that of the aromatic solvent.© 2013 Published by Elsevier B.V.
Jassey V.E.J.,University of Franche Comte |
Shimano S.,Miyagi University of Education |
Dupuy C.,CNRS Coastal and Marine Environment Laboratory |
Toussaint M.-L.,University of Franche Comte |
Gilbert D.,University of Franche Comte
Protist | Year: 2012
Population dynamics and feeding habits of the testate amoebae Nebela tincta and Hyalosphenia papilio were studied along a short " fen" to " bog" gradient in a Sphagnum-dominated mire (Jura, France). Samples were collected in living " top segments" (0-3cm) and early declining " bottom segments" (3-6cm) of Sphagnum fallax peat. Observations of digestive vacuole content and stable isotope analyses ( 13C and 15N) were used to establish the feeding behavior of both testate amoeba species. Owing to their vertical distribution, the feeding habit of H. papilio was described from top segments, and that of N. tincta from bottom segments. Among identified food sources, those most frequently ingested by N. tincta were spores and mycelia of fungi (55%), microalgae (25%) and cyanobacteria (8.5%). For H. papilio, the most frequently ingested prey were ciliates (55%) and microalgae (35%). Nonmetric Multidimensional Scaling analysis clearly demonstrated that the two species did not have the same feeding habit along the " fen-bog" gradient, and furthermore that a significant spatial split exists in the feeding behavior of H. papilio. Additionally, isotope analyses suggested that H. papilio and N. tincta did not have the same trophic position in the microbial food web, probably resulting from their different feeding strategies. © 2011 Elsevier GmbH.
Munakata A.,Miyagi University of Education |
Kobayashi M.,International Christian University
General and Comparative Endocrinology | Year: 2010
Sexual behavior is one of the most profound events during the life cycle of animals that reproduce sexually. After completion of gonadal development that is mediated by various hormones, oviparous teleosts perform a suite of behaviors, often termed as spawning behavior. This is particularly important for teleosts that have their gametes fertilized externally as the behavior patterns ensures the close proximity of both sexes for gamete release, fusion and ultimately the production of offspring. As in other vertebrates, sexual behavior of fish is also under the control of hormones. Testicular androgen is a requirement for male sexual behavior to occur in most fish species that have been studied. Unlike tetrapods, however, ovarian estrogen does not appear to be essential for the occurrence of female sexual behavior for fish that have their gametes fertilized externally. Prostaglandins produced in the ovary after ovulation act as a trigger in some teleosts to induce female sexual behavior. Potentiating effects of gonadotropin-releasing hormone in the brain on sexual behavior are reported in some species. Under endocrine regulation, male and female fish exhibit gender-typical behavior during spawning, but in some fish species there is also some plasticity in their sexual behavior. Sex changing fish can perform both male-typical and female-typical sexual behaviors during their lifetime and this sexual plasticity can also be observed in non-sex changing fish when undergoing hormonal treatment. Although the neuroanatomical basis is not clear in fish, results of field and laboratory observations suggest that some teleosts possess a sexually bipotential brain which can regulate two types of behaviors unlike most other vertebrates which have a discrete sex differentiation of their brain and can only perform gender-typical sexual behavior. © 2009 Elsevier Inc. All rights reserved.
Kashir J.,University of Oxford |
Deguchi R.,Miyagi University of Education |
Jones C.,University of Oxford |
Coward K.,University of Oxford |
Stricker S.A.,University of New Mexico
Molecular Reproduction and Development | Year: 2013
Fertilization causes mature oocytes or eggs to increase their concentrations of intracellular calcium ions (Ca2+) in all animals that have been examined, and such Ca2+ elevations, in turn, provide key activating signals that are required for non-parthenogenetic development. Several lines of evidence indicate that the Ca2+ transients produced during fertilization in mammals and other taxa are triggered by soluble factors that sperm deliver into oocytes after gamete fusion. Thus, for a broad-based analysis of Ca2+ dynamics during fertilization in animals, this article begins by summarizing data on soluble sperm factors in non-mammalian species, and subsequently reviews various topics related to a sperm-specific phospholipase C, called PLCζ, which is believed to be the predominant activator of mammalian oocytes. After characterizing initiation processes that involve sperm factors or alternative triggering mechanisms, the spatiotemporal patterns of Ca2+ signals in fertilized oocytes or eggs are compared in a taxon-by-taxon manner, and broadly classified as either a single major transient or a series of repetitive oscillations. Both solitary and oscillatory types of fertilization-induced Ca2+ signals are typically propagated as global waves that depend on Ca2+ release from the endoplasmic reticulum in response to increased concentrations of inositol 1,4,5-trisphosphate (IP3). Thus, for taxa where relevant data are available, upstream pathways that elevate intraoocytic IP3 levels during fertilization are described, while other less-common modes of producing Ca2+ transients are also examined. In addition, the importance of fertilization-induced Ca2+ signals for activating development is underscored by noting some major downstream effects of these signals in various animals. © 2013 Wiley Periodicals, Inc.
Oda T.,Miyagi University of Education
Journal of Disaster Research | Year: 2016
This report summarizes the conference proceedings of Fostering DRR through Education for Sustainable Development: Toward a Better Future for Children. The conference, held at Tohoku University’s Kawauchi Hagi Hall on March 16, 2015, and attended by over 1,000 participants, focused on disaster risk reduction education within the context of education for sustainable development. This report discusses major themes emerging from presentations and panel discussions and draws some broad conclusions. © 2016, Fuji Technology Press. All rights reserved.
Ishizawa K.,Miyagi University of Education
Plant Cell Monographs | Year: 2014
The intracellular pH of living cells is strictly controlled in each compartment. Under normal conditions, the cytoplasmic pH (pHc) and the vacuolar pH (pHv) of typical plant cells are maintained at slightly alkaline (typically 7.5) and acidic (typically 5.5) values, respectively. A failure to maintain the pH homeostasis of cells leads to cell death. In general, anaerobic conditions induce acidosis in the cytoplasm of plant cells and thereby prolonged anoxia causes cell death. As a result, the regulation of intracellular pH has been an important topic for research in studies of the anoxia tolerance of plant cells (Plant Physiol 100:1–6, 1992; Annu Rev Plant Physiol Plant Mol Biol 48:223–250, 1997; Funct Plant Biol 30:1–47, 2003; Funct Plant Biol 30:999–1036, 2003; Plant Stress 2:1–19, 2008; Annu Rev Plant Biol 59:313–339, 2008). To date many researchers have published review articles to discuss acidosis and pH regulation of plant cells exposed to anaerobic conditions (Encyclopedia of plant physiology, Springer, Berlin, pp. 317–346, 1976; Annu Rev Plant Physiol 30:289–311, 1979; Int Rev Cytol 127:111–173, 1991; Ann Bot 79:39–48, 1997; Regulation of tissue pH in plants and animals, Cambridge University Press, Cambridge, pp. 193–213, 1999; Int Rev Cytol 206:1–44, 2001; Ann Bot 96:519–532, 2005; Plant roots: the hidden half, CRC Press, Boca Raton, Chapter 23, pp. 1–18, 2013). In this review, I will summarize the proposed mechanisms to control intracellular pH and include a brief discussion about anoxia tolerance on the basis of the limited information available for plant cells possessing extremely strong tolerance to anoxia. ©Springer-Verlag Wien 2014
Kawamura T.,Miyagi University of Education |
Stevens C.H.,San Jose State University
Journal of Paleontology | Year: 2012
Four new species of colonial corals, one previously described coral, and two other unidentified species of coral have been recovered from the Baird Formation in the Klamath Mountains of northwestern California. The newly erected species are Heritschioides armstrongi n. sp., Pararachnastraea klamathensis n. sp., P. watkinsi n. sp., and P. kabyaiensis n. sp. These corals are associated with the fusulinids Millerella marblensis Thompson, 1944, Paramillerella Thompson, 1951, and Pseudostaffella Thompson, 1942, emend Groves, 1984, suggesting an early Atokan (Bashkirian) age. Both the coral and foraminiferal faunas bear a resemblance to those of similar age in the Brooks Range, Alaska, which could suggest geographic proximity between the two terranes at that time. These corals also represent the earliest known occurrence of the Family Durhamididae. © 2012 The Paleontological Society.