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Joplin, MO, United States

Missouri Southern State University is a public, state university located in Joplin, in the U.S. state of Missouri. Missouri Southern State University was formerly Missouri Southern State College and is also known as Missouri Southern, MSSU, or MoSo for short. Established in 1937 as Joplin Junior College, Missouri Southern became a four-year college in 1968 and became state-assisted four-year college known as Missouri Southern State College in 1977. In 2003, the Missouri General Assembly authorized the renaming of the college to Missouri Southern State University–Joplin, and in 2005 the university dropped Joplin from its name. Wikipedia.

Lin W.-C.,University of Nebraska Medical Center | Schmidt J.W.,University of Nebraska Medical Center | Creamer B.A.,University of Nebraska Medical Center | Creamer B.A.,Missouri Southern State University | And 2 more authors.
PLoS ONE | Year: 2013

The Signal Transducer and Activator of Transcription 5 (Stat5) plays a significant role in normal hematopoiesis and a variety of hematopoietic malignancies. Deficiency in Stat5 causes impaired cytokine-mediated proliferation and survival of progenitors and their differentiated descendants along major hematopoietic lineages such as erythroid, lymphoid, and myeloid cells. Overexpression and persistent activation of Stat5 are sufficient for neoplastic transformation and development of multi-lineage leukemia in a transplant model. Little is known, however, whether a continuous activation of this signal transducer is essential for the maintenance of hematopoietic malignancies. To address this issue, we developed transgenic mice that express a hyperactive mutant of Stat5 in hematopoietic progenitors and derived lineages in a ligand-controlled manner. In contrast to the transplant model, expression of mutant Stat5 did not adversely affect normal hematopoiesis in the presence of endogenous wildtype Stat5 alleles. However, the gain-of-function of this signal transducer in mice that carry Stat5a/b hypomorphic alleles resulted in abnormally high numbers of circulating granulocytes that caused severe airway obstruction. Downregulation of hyperactive Stat5 in diseased animals restored normal granulopoiesis, which also resulted in a swift clearance of granulocytes from the lung. Moreover, we demonstrate that Stat5 promotes the initiation and maintenance of severe granulophilia in a cell autonomous manner. The results of this study show that the gain-of-function of Stat5 causes excessive granulopoiesis and prolonged survival of granulocytes in circulation. Collectively, our findings underline the critical importance of Stat5 in maintaining a normal balance between myeloid and lymphoid cells during hematopoiesis, and we provide direct evidence for a function of Stat5 in granulophilia-associated pulmonary dysfunction. © 2013 Lin et al. Source

Brueggen-Boman T.R.,Missouri Southern State University | Choi S.-E.,Arkansas State University | Bouldin J.L.,Arkansas State University
Southeastern Naturalist | Year: 2015

This 4-y study monitored 6 sites located in the upper watershed of the Strawberry River, AR, where multiple types of best-management practices (BMPs) were implemented in an attempt to alleviate the impacts of cattle grazing on adjacent waterways. The water-quality variables we assessed included turbidity, total suspended solids (TSS), and concentrations of NO2 -, NO3 -, PO4 3-, Escherichia coli, and chlorophyll-a. We calculated the average annual sediment loading for comparison to published acceptable total-maximum annual load (TMAL). The mean values detected for most parameters that we assessed were within acceptable state limits and reference-stream values for the Ozark Highlands ecoregion. Following BMP implementation, all sites showed significant increases in at least one variable, and the concentration of E. coli for 3 of the sampling locations exceeded the maximum allowable concentration. The estimated sediment loading was within the accepted TMAL. We conclude that implementation of BMPs was not effective at improving water quality during the time-frame of our study. Our results suggest that maintaining desired water quality in this watershed may require the use of BMPs that are: (a) specifically targeted to limit the parameters of concern (e.g., E.coli), and (b) implemented in specific locations of concern rather than dispersed throughout the watershed. We also offer suggestions for future studies of this type to improve the study design in an effort to more efficiently and effectively determine the impact of BMP implementation. © 2015, BioOne. All rights reserved. Source

Summerfield J.,Missouri Southern State University
Journal of Chemical Education | Year: 2013

The lithium ion battery will be a reliable electrical resource for many years to come. A simple model of the lithium ions motion due to changes in concentration and voltage is presented. The battery chosen has LiCoO2 as the cathode, LiPF6 as the electrolyte, and LiC6 as the anode. The concentration gradient and voltage gradient is linearized in two forms of Fick's first law of diffusion. The voltage gradient increases the motion of the lithium ions by a factor of 100 compared to the concentration gradient. Possible extensions of this simple model are also addressed. © 2013 The American Chemical Society and Division of Chemical Education, Inc. Source

Rodik T.,Missouri Southern State University | McDermott B.,University of Arkansas
Journal of Sport Rehabilitation | Year: 2016

Clinical Scenario: Lateral epicondylitis (LE) is a relatively common pathology capable of producing chronic debilitation in a variety of patients. A newer treatment for orthopedic conditions is platelet-rich plasma (PrP) local injection. Focused Clinical Question: Is PrP a more appropriate injection therapy for LE than other common injections such as corticosteroid or whole blood? Summary of Key Findings: Four studies were included: 1 randomized controlled trial (RCT), 2 double-blind RCTs, and 1 cohort study. Two studies involved comparisons of PrP injection to corticosteroid injection. One of the studies involved a 2-y follow-up while another involved a 1-y follow-up. Another study involved the comparison of PrP injection with whole-blood injection with a 6-mo follow-up. The final study included a PrP-injection group and control group. The 2 studies involving PrP vs corticosteroid injections with 2-y and 1-y follow-ups both favored PrP over corticosteroid injection in terms of pain reduction and function increases. The third study favored PrP injections over wholeblood injections at 6 mo regarding pain reduction. All studies demonstrated significant improvements with PrP over comparison injections or no injection. Clinical Bottom Line: PrP injections provide more favorable pain and function outcomes than whole blood and corticosteroid injections for 1-2 y after injection. Strength of Recommendation: Consistent findings from RCTs suggest level 1b evidence in support of PrP injection as a treatment for LE. © 2016 Human Kinetics, Inc. Source

Old S.R.,Missouri Southern State University | Naveh-Benjamin M.,University of Missouri
Psychology and Aging | Year: 2012

Previous research has shown that people-especially older adults-have a special difficulty in learning the names of newly encountered people. This is potentially attributable to the lack of direct link in memory between a face and name. The present experiments investigated whether older and younger adults could use other semantic information about a person (i.e., a "mediator") to indirectly link a name to a face. In each of two experiments, older and younger adults prelearned associations between semantic information (character information or occupations) and names. They then attempted to learn links between faces and either the names or semantic information. In the "unmediated" condition, participants learned only one piece of information (either the name or the semantic information) about each face, whereas in the "mediated" condition, they learned both the to-be-tested information as well as the "mediator" (i.e., both the name and the other semantic information). Experiment 1 showed that, at a simple level, both age groups could use character information ("good" or "bad") to help recognize people's names, given their faces. Experiment 2 showed that knowing the occupation associated with a name helped both age groups to later recall the name associated with a given face. © 2011 American Psychological Association. Source

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