Mirpur University of Science & Technology

www.must.edu.pk
Sita Road, Pakistan

Mirpur University of Science & Technology was formerly a constituent college of University of Azad Jammu and Kashmir as University College of Engineering & Technology Mirpur . It is a state university and the President of Azad Jammu & Kashmir is the Chancellor of the university. The Vice-Chancellor is the executive head and manages the university functions.It offers degrees in five different areas of study in engineering, namely: Computer Systems, Electrical, Civil, Mechanical and Software.The university is situated on Allama Iqbal Road, Mirpur, Azad Kashmir . Wikipedia.


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Ahmad I.,Mirpur University of Science & Technology | Ashraf U.,Mirpur University of Science & Technology | Ghafoor A.,Mirpur University of Science & Technology
Journal of the Chinese Institute of Engineers, Transactions of the Chinese Institute of Engineers,Series A/Chung-kuo Kung Ch'eng Hsuch K'an | Year: 2016

A mobile ad hoc network (MANET) is a wireless, dynamic, infrastructure-less, self-organized, multi-hop, and decentralized network. Each node in MANET can act as a router as well as a work station. Many routing protocols have been developed to increase the efficiency of MANET. The primary objective of this paper is a detailed QoS comparison of reactive (AODV), proactive (DSDV), and hybrid (ZRP) routing protocols of MANET in order to find which routing protocol works best in a particular network scenario. The analysis was made for TCP-based traffic patterns. The performance differentials were analyzed on the basis of normalized routing overhead, packet loss, packet delivery ratio, control packets, end-to-end delay, packet received, and packet sent with a variation of nodes density and mobility. The results were obtained using the NS-2 simulator. © 2016 The Chinese Institute of Engineers


Ahmed M.,Mirpur University of Science & Technology | Anjum M.A.,Bahauddin Zakariya University | Hussain S.,Bahauddin Zakariya University | Ejaz S.,Bahauddin Zakariya University | And 2 more authors.
Erwerbs-Obstbau | Year: 2016

A comprehensive analysis of various horticulturally important morphological traits of sixty pear accessions located in five districts of Azad Jammu and Kashmir (Pakistan) was carried out. Several qualitative and quantitative traits were investigated in situ and after the harvesting of leaf and fruit samples. The rich diversity was observed for qualitative traits (i. e. growth habit, blooming time, intensity of flowering, fruit setting, ripening time, productivity, and fruit shape and color) among pear accessions. As for the quantitative traits, significant variation was observed for leaf area (8.96–27.17 cm2), flowering duration (11–24 days), fruit weight (68.1–322.3 g), average fruit length (2.68–9.87 cm) and average fruit width (1.82–8.12 cm) between pear accessions. Based on qualitative and quantitative data, two dendograms were constructed by using cluster analysis which separated pear accessions into three distinct groups. The cluster analysis showed considerable differences between the accessions for qualitative and quantitative traits. Furthermore, a close association between accessions was noted inside the clusters for qualitative and quantitative traits. The results showed rich diversity and similarity between the pear accessions and needs further assessment at molecular level to elucidate their phylogenetic relationship. © 2016 Springer-Verlag Berlin Heidelberg


Hassan M.,Mirpur University of Science & Technology | Ali Shamim M.,Bursa Orhangazi University | Sikandar A.,National University of Sciences and Technology | Mehmood I.,Mirpur University of Science & Technology | And 3 more authors.
Environmental Monitoring and Assessment | Year: 2015

This study aims at the development of an artificial neural network-based model for the estimation of weekly sediment load at a catchment located in northern part of Pakistan. The adopted methodology has been based upon antecedent sediment conditions, discharge, and temperature information. Model input and data length selection was carried out using a novel mathematical tool, Gamma test. Model training was carried out by using three popular algorithms namely Broyden-Fletcher-Goldfarb-Shanno (BFGS), back propagation (BP), and local linear regression (LLR) using forward selection of input variables. Evaluation of the best model was carried out on the basis of basic statistical parameters namely R-square, root mean squared error (RMSE), and mean biased error (MBE). Results indicated that BFGS-based ANN model outperformed all other models with significantly low values of RMSE and MBE. A strong correlation was also found between the observed and estimated sediment load values for the same model as the value of Nash-Sutcliffe model efficiency coefficient (R-square) was found to be quite high as well. © 2015, Springer International Publishing Switzerland.


Aziz S.,Mirpur University of Science & Technology | Aziz S.,University of Paderborn | Habib-ur-Rehman,Mirpur University of Science & Technology | Ch M.A.,Mirpur University of Science & Technology | And 4 more authors.
Chemistry of Natural Compounds | Year: 2016

A concise route to the synthesis of topopyrone C derivatives is reported. The 1,4-dihydroxyanthraquinone was converted to the target compound 2 using five-step sequences, while only three steps were required to access the said compound, starting from the same anthraquinone. A new one-pot alkylation served as the crucial operation for this new synthesis. Two lengthy steps are eliminated, which not only shorten the reaction but improve the yield too. Spectral techniques were used to confirm the structures of the synthesized compounds. The compound exhibited strong scavenging effect on DPPH and NO radicals. The free radical scavenging effect of the compound was found to be comparable to that of reference antioxidants BHA and ascorbic acid. This study is the first evidence for the radical scavenging property of topopyrone C derivatives. © 2016 Springer Science+Business Media New York


Yasmeen K.,University of Karachi | Mirza M.A.,Mirpur University of Science & Technology | Khan N.A.,University of Karachi | Kausar N.,University of Karachi | And 2 more authors.
SpringerPlus | Year: 2016

Fish is a vital food for humans and many animals. We report an environmental monitoring study to assess the trace metals in fish species caught from Arabian Sea and commercially available in the coastal city Karachi, Pakistan. Heavy metals such as copper, iron, lead and cadmium were determined in the skin, fillet and heart of the fish species Pampus argenteus, Epinephelus chlorostigma, Rachycentron canadum, Scomberomorus commerson, Johnius belangerii, Labeo rohita, Lutjanus argentimaculatus, Trachinotus blochii, Pomadsys olivaceum and Acanthopagrus berda by the atomic absorption spectrophotometer. The concentration (mg kg−1, dry weight) range was: Cd (0.00–0.041), Cu (0.006–0.189), Fe (0.413–4.952) and Pb (0.00–0.569). Cadmium, copper and iron levels were below the tolerable limits whereas concentration of lead in the skins of S. commerson, E. chlorostigma, J. belangerii, A. berda; L. argentimaculatus, fillets of J. belangerii, E. chlorostigma and in the heart of J. belangerii exceeded the recommended limits. Therefore fish skin should be discouraged as food for humans or animals. The results indicate that a number of fish species have higher concentration of heavy metals dangerous for human health. Since the fish P. olivaceum (Dhotar) has the lowest level of trace metals therefore we recommend it for breeding and human consumption. © 2016, The Author(s).


PubMed | COMSATS Institute of Information Technology and Mirpur University of Science & Technology
Type: | Journal: Journal of ethnopharmacology | Year: 2015

Ethnobotanical study was aimed to document indigenous medicinal plants along with the ethnopharmacological therapeutic values, and to explore the frequencies and relative importance of reported plants. Objective of this study was to trace out the disease prevalence pattern with help of informant consensus factor.Visual appraisal approach (VAA) and rapid rural appraisal (RRA) methods along with the group meetings and discussions about wide range of topics in an open-ended questionnaire with local people were employed for collection of qualitative ethnomedicinal data.Current study reported 58 medicinal plants belonging to 33 families, where Rosaceae was the predominant family. Berberis lycium dominated among shrubs, which is used to treat liver problems (jaundice). Females and old people were found more allied to the indigenous healthcare system. Conservation threats to valued medicinal plants were detected during course of the study.Local communities of the study area are highly dependent on medicinal plants and reported the best therapeutic results for specific disorders. Urgent attention must be paid on conservation of medicinal flora, comprehensive documentation of indigenous medicinal knowledge and pharmacological/phytochemical validation of reported plants for specific diseases.


PubMed | University of Sargodha, Pakistan Council for Scientific and Industrial Research, Mirpur University of Science & Technology and Quaid-i-Azam University
Type: Journal Article | Journal: Journal of ethnopharmacology | Year: 2014

Ethnomedicinal reports are important for the discovery of new crude drugs from reported medicinal plants with high use value. The current study aimed to document the medicinal flora as well as medicinal knowledge of indigenous plants of local communities from Layyah district, Punjab Province, Pakistan.Rapid appraisal approach (RAA), semi-structured interviews, group meetings with herbalists, landowners and local people having awareness about the medicinal action of plants were employed to collect the data. Use values (UV) and frequency of citation (FC) were calculated to check the relative importance of plants.The current ethnomedicinal study reported 125 medicinal plant species diversified from 106 genus belonging to the 43 different families and Poaceae was the predominant family over others with 16 reported medicinal plants. Wild herbaceous plants were the predominant over other life forms while among plant parts, leaves contributed 32% followed by the stem (27%), fruit and flowers (15%). Allium sativum exhibited the highest use vale (UV) 0.92 while the lowest UV was exhibited by Lasiurus scindicus which was 0.15.Local communities of district Layyah still have a strong faith on herbal medicines for basic healthcare needs. Indigenous plants having high UV and FC should be subjected to the detailed phytochemical investigations to explore new natural drugs.


PubMed | National University of Sciences and Technology, Mirpur University of Science & Technology and Bursa Orhangazi University
Type: Journal Article | Journal: Environmental monitoring and assessment | Year: 2015

This study aims at the development of an artificial neural network-based model for the estimation of weekly sediment load at a catchment located in northern part of Pakistan. The adopted methodology has been based upon antecedent sediment conditions, discharge, and temperature information. Model input and data length selection was carried out using a novel mathematical tool, Gamma test. Model training was carried out by using three popular algorithms namely Broyden-Fletcher-Goldfarb-Shanno (BFGS), back propagation (BP), and local linear regression (LLR) using forward selection of input variables. Evaluation of the best model was carried out on the basis of basic statistical parameters namely R-square, root mean squared error (RMSE), and mean biased error (MBE). Results indicated that BFGS-based ANN model outperformed all other models with significantly low values of RMSE and MBE. A strong correlation was also found between the observed and estimated sediment load values for the same model as the value of Nash-Sutcliffe model efficiency coefficient (R-square) was found to be quite high as well.


PubMed | National Institute for Biotechnology and Genetic Engineering NIBGE, The University of Faisalabad and Mirpur University of Science & Technology
Type: | Journal: EXCLI journal | Year: 2015

Currently licensed typhoid vaccines are based on Vi capsular polysaccharides. Recent molecular reports from typhoid endemic countries state that Salmonella enterica serovar Typhi (S. Typhi) Vi negative strains occur naturally and cause typhoid fever which is indistinguishable from disease caused by Vi positive strains. Vaccine based on Vi polysaccharide may not protect patients if the invading S. Typhi are negative for Vi. The lipopolysaccharide (LPS) is an essential component of S. Typhi outer membrane in which O-specific polysaccharide (OSP) is a protective antigen and universal candidate for vaccine development. In this study, S. Typhi Vi negative isolates were discriminated from Vi positive isolates through a duplex PCR using primers of fliC-d (599bp) and tviA (495bp) genes. The LPS of S. Typhi Vi negative isolates was extracted by hot phenol method and OSP was purified by core hydrolysis. The yield of extracted LPS was 91 mg/L and that of purified OSP was 49.14 mg/L of culture broth. LPS showed ladder like appearance by zinc imidazole staining following SDS-PAGE. Whole cell challenged mice sera were used for in vitro antigenicity evaluation of the purified LPS and OSP. The antigenicity was found adequate by immunodiffusion assay. To our knowledge, this is the first report of purification and antigenic evaluation of LPS of a Vi negative S. Typhi isolate. The purified OSP from S. Typhi Vi negative isolate may be coupled with a carrier protein to produce universal low cost conjugate vaccine candidates for use in typhoid endemic regions.

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