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Xu M.-M.,Jiangsu University | Yu X.-H.,Military Training Medical Institute of Chinese Nanjing Military Command | Luo X.,Military Training Medical Institute of Chinese Nanjing Military Command | Ma C.-Y.,Jiangsu University | Zhao Z.-Y.,Military Training Medical Institute of Chinese Nanjing Military Command
Chinese Journal of Tissue Engineering Research | Year: 2013

BACKGROUND: Doctors often use autoallergic hamstring double-bundle and single-bundle for the reconstruction of anterior cruciate ligament, but there is a controversy on which method is better. OBJECTIVE: To evaluate the clinical outcome of double-bundle versus single-bundle autoallergic hamstring for the reconstruction of anterior cruciate ligament. METHODS: Randomized controlled trials about comparing double-bundle with single-bundle autoallergic hamstring for the reconstruction of anterior cruciate ligament were collected from PubMed database, Cochrane library, Springerlink database, CNKI database and CBM database. The Jadad's scale was used to assess the methodological quality of the randomized controlled trials and Cochrane collaboration's RevMan 5.0 software was used to perform the Meta analysis. RESULTS AND CONCLUSION: Fifteen randomized controlled trials totally 1 008 patients met the inclusion criteria and included. Meta-analysis results showed that there was statistical difference of postoperative KT-1000 or KT-2000 arthrometer mesurement between double-bundle and single-bundle reconstruction [weighted mean difference (WMD)=-0.51, 95% confidence interval (CI) (-0.74, -0.28), P < 0.000 1], there was significant difference of the negative pivot-shift testing [relative risk (RR)=1.27, 95%CI(1.11, 1.45), P=0.000 3], as well as the postoperative Lysholm scores [WMD=-2.10, 95%CI(-3.65, -0.55), P=0.008]. But there was no statistical differences of IKDC final score [RR=1.04, 95%CI(0.99, 1.06), P=0.10]. The double-bundle autoallergic hamstring is superior to single-bundle for anterior cruciate ligament reconstruction on recovering stability of knee joint, but they are similar in recovering the functions of knee joint. Source

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