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Belgrade, Serbia

Background/Aim. Quality of life related to health should be seen as a multidimensional concept that, in addition to the physical symptoms associated with a disease and treatment, should include physical, psychological and social functioning of a person. The primary objective of this study was to use the Serbian preliminary version of the Geriatric Oral Health Assessment Index (GOHAI) questionnaire in oder to examine the consistency, reliability and stability, as well as an introduction to the verification tool. Methods. The GOHAI questionnaire with 6-level Likert scale, translated into Serbian, including the relevant oral health characteristics (oral hygiene, required dentures, number of teeth extracted), was filled by five specialists in prosthodontics for 30 randomly selected respondents, before and after the dental prosthetic treatment. Subsequently, in order to measure the reliability of the questionnaire, 27 patients were reinterviewed. Results. The value of Cronbach's Alpha Coefficient (Crα) before the treatment was 0.878, and after the treatment it was 0.788 confirming the internal consistency and stability of the questionnaire. The validity of discriminatory properties of the GOHAI was confirmed by the Spearman's correlation coefficient (r), which was highly significantly associated with oral health characteristics, confirming the high reliability of the measurement. The results of test-retest analysis measured by the individual Pearson's correlation coefficient (r) were in the range of 0.34–0.97, and for the total score r was 0.927, while the Kappa coefficient was 0.63. The correlation analysis of the GOHAI score before the treatment showed that for 10 questions there was a statistically significant correlation of the score with the answers to the questions, and for 6 questions Spearman’s r was ≥ 0.7. After the treatment a highly significant correlation of the GOHAI was shown with the answers to 10 questions, while for 5 questions the Spearman’s r was > 0.6. The GOHAI average score before the treatment was 19.44 ± 11.12, and after the treatment 2.77 ± 3.83, where the lower value indicates better quality of life. Conclusion. The results of this pilot study confirm internal consistency and stability of the Serbian preliminary version of the GOHAI questionnaire and the causal relation between the quality of life and the characteristics of oral health of the patients with dentures. Accordingly, instrument verification is recommended. © 2015, Institut za Vojnomedicinske Naucne Informacije/Documentaciju. All rights reserved. Source


Birgfeld C.B.,University of Washington | Saltzman B.S.,Craniofacial Center | Luquetti D.V.,University of Washington | Latham K.,Military Medical Center | And 2 more authors.
Cleft Palate-Craniofacial Journal | Year: 2013

Background and Purpose: Three-dimensional surface imaging is used in many craniofacial centers. However, few data exist to indicate whether such systems justify their cost. Craniofacial microsomia is associated with wide phenotypic variability and can affect most facial features. The purpose of this study is to compare three-dimensional versus two-dimensional images for classification of facial features in individuals with craniofacial microsomia. Methods: We obtained a series of two-dimensional and three-dimensional images of 50 participants, aged 0-20 years, diagnosed with craniofacial microsomia, microtia, or Goldenhar syndrome. Three clinicians classified the craniofacial features on each image, and ratings were compared by calculating kappa statistics.We also evaluated image quality using a 5-point Likert scale. Results: Reliability estimates were high for most features using both two-dimensional and three-dimensional image data. Our three-dimensional protocol did not allow for scoring of facial animation, occlusal cant, or tongue anomalies. Image quality scores for the mandible and soft tissue assessment were higher for three-dimensional images. Raters preferred two-dimensional photographs for assessment of the ear, ear canal, and eyes. Conclusions: Both three-dimensional and two-dimensional images provide useful data for objective characterization of the craniofacial features affected in craniofacial microsomia. A series of two-dimensional images has relative advantages for assessment of some specific features, such as the ear, though three-dimensional images may have advantages for quantitative analysis and qualitative assessment of deformities of the jaw and soft tissue. These results should apply to any assessment of these features with or without a craniofacial microsomia diagnosis. © Copyright 2013 American Cleft Palate-Craniofacial Association. Source


Derache F.,Military Hospital Sainte Anne | Audoual T.,Military Medical Center
Aviation Space and Environmental Medicine | Year: 2010

Dental fractures induced by changes in atmospheric pressure, called odontocrexis, are described in aviation dentistry articles. According to previous reports, these pathologies are induced exclusively in teeth with defective dental restorations. Nevertheless, in this case report we describe a tooth fracture occurring on an apparently sound tooth in a fighter pilot during a flight. All usual etiologies of this odontocrexis can generally be eliminated. This atypical fracture shows that all pathophysiology and contributing factors of odontocrexis are still widely unknown. Copyright © by the Aerospace Medical Association. Source


Feher E.,Hungarian Academy of Sciences | Pazar P.,Szent Istvan University | Lengyel G.,Military Medical Center | Phan T.G.,Blood Systems Research Institute | And 2 more authors.
Virus Genes | Year: 2015

The genomic sequence of a novel gyrovirus (GyV) 3 strain was detected from the fecal sample of a pet ferret. The length (2,359 nt) and the basic genomic structure of this strain was very similar to that of the single known GyV3 reference strain, whereas the genome sequence identity between the two strains was only 76 %. Similarly, moderate sequence homology was found within the predicted protein coding regions, VP1 (nt, 72 %; aa, 76 %), VP2 (nt, 84 %; aa, 85 %), and VP3 (nt, 85 %; aa, 73 %). Sequence identities were lower when comparing our strain with other GyV species (48–65 % genome-wide nt identity). Phylogenetic analysis of the coding regions clustered the ferret origin GyV3 strain within Clade A. Although the available whole genomic sequence of novel GyVs permits limited conclusions to be drawn regarding the classification of the Hungarian GyV3 strain, our data indicate that this novel strain may be considered as a new genotype within GyV3. Further investigations are needed to reveal the genetic diversity and biological properties of newly described members of the Gyrovirus genus. © 2014, Springer Science+Business Media New York. Source


Milobratovic D.,Military Medical Center | Jankovic S.,University of Belgrade | Vukicevic J.,University of Belgrade | Marinkovic J.,University of Belgrade | Jankovic J.,University of Belgrade
Mycoses | Year: 2013

Onychomycosis is a common, chronic fungal nail infection that can have a significant negative impact on patients' physical and social functioning and emotional well-being. This study was undertaken to assess health-related quality of life (HRQoL) in patients with toenail onychomycosis. The Onychomycosis QoL questionnaire (ONYCHO), as a disease-specific instrument, and the Short Form 36 Health Survey (SF-36) as a generic instrument, were applied in 140 consecutive patients affected by onychomycosis. Women and patients who were experiencing toenail onychomycosis for more than 2 years were reporting worse disease-specific HRQoL. The patients working in blue-collar occupations and patients with greater involvement of individual nails were more affected by onychomycosis regarding symptoms. The results of this study confirm that although onychomycosis is not a life-threatening disease, it can significantly reduce patients' QoL. © 2013 Blackwell Verlag GmbH. Source

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