Midway College is an independent, liberal arts college with approximately 1,800 students located in Midway, Kentucky. Related by covenant to the Christian Church , it currently offers two and four-year degrees. Midway is the only women's college in Kentucky. The all-female Day College offers majors in four pillar programs: business, equine studies, nursing, and teacher education.In addition to the Day College, Midway College offers programs to adult men and women, through the evening and weekend School for Career Development , offered on the Midway Campus and in more than 18 sites across Kentucky, and also through Midway College ONLINE. Both SCD and ONLINE offer accelerated degree-completion programs for working adults in popular programs such as Organizational Administration and Leadership, Homeland Security Corporate Management and Assessment, and Teacher Education, among others.In August 2011, Midway delayed the of launch of the new School of Pharmacy in the eastern Kentucky community of Paintsville. The school was supposed to enroll up to 80 students a year and intended to offer a fully accredited Pharm.D. degree. The School of Pharmacy was to occupy space at Big Sandy Community and Technical College while it seeks a site for its own campus.The mission of Midway College: "As Kentucky's only college for Women and as a forerunner in coeducational adult accelerated learning, Midway College empowers undergraduate and graduate students as leaders through a professionally-oriented liberal arts education." Wikipedia.
Johnson K.A.,Vanderbilt University |
Jones C.K.,Vanderbilt University |
Tantawy M.N.,Vanderbilt University |
Bubser M.,Vanderbilt University |
And 6 more authors.
Neuropharmacology | Year: 2013
Metabotropic glutamate receptors (mGlus) are 7 Transmembrane Spanning Receptors (7TMs) that are differentially expressed throughout the brain and modulate synaptic transmission at both excitatory and inhibitory synapses. Recently, mGlus have been implicated as therapeutic targets for many disorders of the central nervous system, including Parkinson's disease (PD). Previous studies have shown that nonselective agonists of group III mGlus have antiparkinsonian effects in several animal models of PD, suggesting that these receptors represent promising targets for treating the motor symptoms of PD. However, the relative contributions of different group III mGlu subtypes to these effects have not been fully elucidated. Here we report that intracerebroventricular (icv) administration of the mGlu8-selective agonist (S)-3,4-dicarboxyphenylglycine (DCPG [ 2.5, 10, or 30 nmol]) does not alleviate motor deficits caused by acute (2 h) treatment with haloperidol or reserpine. However, following prolonged pretreatment with haloperidol (three doses evenly spaced over 18-20 h) or reserpine (18-20 h), DCPG robustly reverses haloperidol-induced catalepsy and reserpine-induced akinesia. Furthermore, DCPG (10 nmol, icv) reverses the long-lasting catalepsy induced by 20 h pretreatment with the decanoate salt of haloperidol. Finally, icv administration of DCPG ameliorates forelimb use asymmetry caused by unilateral 6-hydroxydopamine lesion of substantia nigra dopamine neurons. These findings suggest that mGlu 8 may partially mediate the antiparkinsonian effects of group III mGlu agonists in animal models of PD in which dopamine depletion or blockade of D2-like dopamine receptors is prolonged and indicate that selective activation of mGlu8 may represent a novel therapeutic strategy for alleviating the motor symptoms of PD. This article is part of a Special Issue entitled 'Metabotropic Glutamate Receptors'. © 2012 Elsevier Ltd. All rights reserved.
News Article | October 31, 2016
AffordableCollegesOnline.org, a leading source of higher education and student information, has named the Best Online Colleges in Kentucky for 2016-2017. A total of 31 schools received honors, with Western Kentucky University, Brescia University, Eastern Kentucky University, Midway College and Clear Creek Baptist Bible College scoring at the top for four-year schools and Madisonville Community College, Maysville Community and Technical College, Henderson Community College, Gateway Community and Technical College and Hazard Community and Technical College scoring at the top for two-year schools. "In 2013, 20 percent of the overall hours students spent learning at Kentucky colleges and universities were online learning hours,” said Dan Schuessler, CEO and Founder of AffordableCollegesOnline.org. "As a growing number of students turn to online college programs in Kentucky, they want to find schools who are offering the best combination of quality and value. These rankings give students that insight.” In order to qualify for Kentucky’s Best Online College lists, AffordableCollegesOnline.org requires schools to hold regional accreditation and be two year or four year public or private not-for-profit institutions. To maintain affordability standards, only two year schools providing in-state tuition under $5,000 annually and four year colleges with in-state tuition under $25,000 were considered. To see the full list of schools and learn more about the specific data points used to determine each online college’s rank, follow the link below: Ashland Community and Technical College Big Sandy Community and Technical College Bluegrass Community and Technical College Gateway Community and Technical College Hazard Community and Technical College Henderson Community College Hopkinsville Community College Jefferson Community and Technical College Madisonville Community College Maysville Community and Technical College Owensboro Community and Technical College Somerset Community College Southcentral Kentucky Community and Technical College Southeast Kentucky Community and Technical College West Kentucky Community and Technical College AffordableCollegesOnline.org began in 2011 to provide quality data and information about pursuing an affordable higher education. Our free community resource materials and tools span topics such as financial aid and college savings, opportunities for veterans and people with disabilities, and online learning resources. We feature higher education institutions that have developed online learning environments that include highly trained faculty, new technology and resources, and online support services to help students achieve educational and career success. We have been featured by nearly 1,100 postsecondary institutions and nearly 120 government organizations.
News Article | March 2, 2017
The Community for Accredited Online Schools, a leading resource provider for higher education information, has compiled a list of the best colleges and universities with online programs in Kentucky for 2017. Of the 20 four-year schools that were ranked, University of Kentucky, University of Louisville, Eastern Kentucky University, Murray State University and Western Kentucky University came in as the top five institutions. The top 16 two-year schools were also included, with West Kentucky Community and Technical College, Maysville Community and Technical College, Bluegrass Community and Technical College, Jefferson Community and Technical College and Somerset Community College named as the top five. “The schools on our list have been evaluated based on more than a dozen unique data points,” said Doug Jones, CEO and founder of AccreditedSchoolsOnline.org. “The results is a selection of the best online curriculum, program variety, student resources and graduation outcomes in Kentucky.” To earn a spot on the Best Online Schools list, colleges and universities in Kentucky must be institutionally accredited, public or private not-for-profit entities. Each college is also judged based on such criteria as student/teacher ratios, employment services, student resources, graduation rates and financial aid availability. For more details on where each school falls in the rankings and the data and methodology used to determine the lists, visit: The Best Online Four-Year Schools in Kentucky for 2017 include the following: Asbury University Brescia University Campbellsville University Eastern Kentucky University Georgetown College Kentucky Christian University Kentucky State University Kentucky Wesleyan College Lindsey Wilson College Midway College Morehead State University Murray State University Northern Kentucky University The Southern Baptist Theological Seminary Thomas More College Union College University of Kentucky University of Louisville University of the Cumberlands Western Kentucky University Kentucky’s Best Online Two-Year Schools for 2017 include the following: Ashland Community and Technical College Big Sandy Community and Technical College Bluegrass Community and Technical College Elizabethtown Community and Technical College Gateway Community and Technical College Hazard Community and Technical College Henderson Community College Hopkinsville Community College Jefferson Community and Technical College Madisonville Community College Maysville Community and Technical College Owensboro Community and Technical College Somerset Community College Southcentral Kentucky Community and Technical College Southeast Kentucky Community and Technical College West Kentucky Community and Technical College About Us: AccreditedSchoolsOnline.org was founded in 2011 to provide students and parents with quality data and information about pursuing an affordable, quality education that has been certified by an accrediting agency. Our community resource materials and tools span topics such as college accreditation, financial aid, opportunities available to veterans, people with disabilities, as well as online learning resources. We feature higher education institutions that have developed online learning programs that include highly trained faculty, new technology and resources, and online support services to help students achieve educational success.
News Article | November 28, 2016
Leading higher education information and resource provider AffordableCollegesOnline.org is highlighting schools with top online health sciences degree programs in a new ranking for 2016-2017. Two lists compare four-year and two-year schools offering health science degree programs nationwide, determining which offer the best combination of cost and quality for students. Of the lists of top 100 colleges, the highest finishers among four-year schools include the University of Mississippi, Washburn University, Siena Heights University, Weber State University and Davenport University, while top two-year schools include East Mississippi Community College, Holmes Community College, Hutchinson Community College, Metropolitan Community College and Barton County Community College. "Employment in healthcare occupations is projected to grow 19 percent, or much faster than the national average, from 2014 to 2024,” said Dan Schuessler, CEO and Founder of AffordableCollegesOnline.org. “Students pursuing health science degrees can now find affordable, high quality learning options online through these schools, who are ultimately being highlighted here for their efforts to help students excel.” AffordableCollegesOnline.org has several minimum eligibility requirements each school on their rankings must meet. Colleges must be accredited, public or private not-for-profit institutions and must offer in-state tuition rates as follows: under $5,000 per year for two-year schools; under $25,000 per year for four-year schools. Those meeting eligibility requirements are then scored and ranked based on more than a dozen school-specific statistics, including financial aid offerings and graduation rates. Each school recognized on the top online health sciences degree programs list is included below. For more information on each school’s score and the data and methodology used to rank each can be found at: The Best Two-Year Schools for Online Health Sciences Students in 2016-2017: Allen County Community College Barton County Community College Beaufort County Community College Bluegrass Community and Technical College Central Texas College Colby Community College Collin College Columbus State Community College Cowley County Community College Crowder College Dakota College at Bottineau East Mississippi Community College Forsyth Technical Community College Gateway Community and Technical College GateWay Community College Great Falls College Montana State University Hazard Community and Technical College Holmes Community College Hutchinson Community College Indian Hills Community College Kansas City Kansas Community College Kilgore College Lakeshore Technical College Lanier Technical College Lenoir Community College Madisonville Community College Maysville Community and Technical College Metropolitan Community College National Park College North Central Missouri College North Dakota State College of Science Northwest Mississippi Community College Oklahoma City Community College Pamlico Community College Panola College Pitt Community College San Juan College Seward County Community College and Area Technical School Sinclair College Southwest Mississippi Community College Southwestern Community College Spokane Community College Spokane Falls Community College State Fair Community College Three Rivers Community College Truckee Meadows Community College Tyler Junior College Western Nebraska Community College Western Wyoming Community College Williston State College The Best Four-Year Schools for Online Health Sciences Students in 2016-2017: Allen College Augusta University Baker College Brigham Young University - Idaho Clarkson College Concordia University - Saint Paul Dakota State University Davenport University East Carolina University Ferris State University Goodwin College Granite State College Indiana University - Purdue University Indianapolis Keiser University - Fort Lauderdale Kent State University at Kent Midway College Midwestern State University Mississippi University for Women Montana State University - Billings Nebraska Methodist College of Nursing & Allied Health North Carolina A & T State University Northern Arizona University Oregon Institute of Technology Peirce College Presentation College Rutgers University - New Brunswick Siena Heights University St. Petersburg College SUNY Polytechnic Institute The University of Texas Health Science Center at San Antonio Thomas University Tiffin University University of Alabama at Birmingham University of Arkansas at Little Rock University of Cincinnati - Main Campus University of Florida University of Louisiana at Monroe University of Mississippi University of Missouri - Columbia University of Northern Colorado University of Oklahoma - Health Sciences Center University of Southern Indiana University of Toledo Viterbo University Washburn University Weber State University Western Carolina University Western Kentucky University Winston-Salem State University Youngstown State University AffordableCollegesOnline.org began in 2011 to provide quality data and information about pursuing an affordable higher education. Our free community resource materials and tools span topics such as financial aid and college savings, opportunities for veterans and people with disabilities, and online learning resources. We feature higher education institutions that have developed online learning environments that include highly trained faculty, new technology and resources, and online support services to help students achieve educational and career success. We have been featured by nearly 1,100 postsecondary institutions and nearly 120 government organizations.
Kharel M.K.,University of Kentucky |
Kharel M.K.,Midway College |
Pahari P.,University of Kentucky |
Shaaban K.A.,University of Kentucky |
And 3 more authors.
Organic and Biomolecular Chemistry | Year: 2012
The functional roles of all proposed enzymes involved in the post-PKS redox reactions of the biosynthesis of various landomycin aglycones were thoroughly studied, both in vivo and in vitro. The results revealed that LanM2 acts as a dehydratase and is responsible for concomitant release of the last PKS-tethered intermediate to yield prejadomycin (10). Prejadomycin (10) was confirmed to be a general pathway intermediate of the biosynthesis. Oxygenase LanE and the reductase LanV are sufficient to convert 10 into 11-deoxylandomycinone (5) in the presence of NADH. LanZ4 is a reductase providing reduced flavin (FMNH) co-factor to the partner enzyme LanZ5, which controls all remaining steps. LanZ5, a bifunctional oxygenase-dehydratase, is a key enzyme directing landomycin biosynthesis. It catalyzes hydroxylation at the 11-position preferentially only after the first glycosylation step, and requires the presence of LanZ4. In the absence of such a glycosylation, LanZ5 catalyzes C5,6-dehydration, leading to the production of anhydrolandomycinone (8) or tetrangulol (9). The overall results provided a revised pathway for the biosynthesis of the four aglycones that are found in various congeners of the landomycin group. This journal is © 2012 The Royal Society of Chemistry.
Pahari P.,University of Kentucky |
Kharel M.K.,University of Kentucky |
Kharel M.K.,Midway College |
Shepherd M.D.,University of Kentucky |
And 3 more authors.
Angewandte Chemie - International Edition | Year: 2012
Teamwork: Defucogilvocarcin M (1, see scheme) was synthesized in a one-pot, enzymatic reaction from acetyl-CoA and malonyl-CoA by a combination of 15 enzymes obtained from E. coli as well as the gilvocarcin, jadomycin, and ravidomycin biosynthetic pathways. The mixture of enzymes was systematically reduced and varied to further delineate the sequence of reactions in the complex, post-polyketide steps of gilvocarcin biosynthesis. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Kharel M.K.,Midway College |
Rohr J.,University of Kentucky
Current Opinion in Chemical Biology | Year: 2012
The exact sequence of events in biosyntheses of natural products is essential not only to understand and learn from nature's strategies and tricks to assemble complex natural products, but also for yield optimization of desired natural products, and for pathway engineering and muta-synthetic preparation of analogues of bioactive natural products. Biosyntheses of natural products were classically studied applying in vivo experiments, usually by combining incorporation experiments with stable-isotope labeled precursors with cross-feeding experiments of putative intermediates. Later genetic studies were dominant, which consist of gene cluster determination and analysis of gene inactivation experiments. From such studies various biosynthetic pathways were proposed, to a large extent just through in silico analyses of the biosynthetic gene clusters after DNA sequencing. Investigations of the complex biosyntheses of the angucycline group anticancer drugs landomycin, jadomycin and gilvocarcin revealed that in vivo and in silico studies were insufficient to delineate the true biosynthetic sequence of events. Neither was it possible to unambiguously assign enzyme activities, especially where multiple functional enzymes were involved. However, many of the intriguing ambiguities could be solved after in vitro reconstitution of major segments of these pathways, and subsequent systematic variations of the used enzyme mixtures. This method has been recently termed 'combinatorial biosynthetic enzymology'. © 2012 Elsevier Ltd.
Havens J.R.,University of Kentucky |
Young A.M.,University of Kentucky |
Havens C.E.,Midway College
Archives of Pediatrics and Adolescent Medicine | Year: 2011
Objectives: To compare the prevalence of nonmedical prescription drug use among adolescents residing in urban, suburban, and rural areas of the United States and to determine factors independently associated with rural nonmedical prescription drug use among adolescents aged 12 to 17 years. Design: Cross-sectional, population-based survey. Setting: Noninstitutionalized residents in the United States. Participants: Participants included adolescents aged 12 to 17 years (N = 17 872), most of whom were residing in urban areas (53.2%), male (51%), and white (59%). Main Exposure: Living in rural compared with urban area. Main Outcome Measures: Nonmedical use of prescription drugs (pain relievers, tranquilizers, sedatives, and stimulants). Data were from the 2008 National Survey on Drug Use and Health. Results: Rural adolescents were 26% more likely than urban adolescents to have used prescription drugs nonmedically (adjusted odds ratio, 1.26; 95% confidence interval, 1.01-1.57) even after adjustment for race, health, and other drug and alcohol use. When examining the rural adolescents in particular, factors positively associated with nonmedical use of prescription drugs included decreased health status, major depressive episode(s), and other drug (marijuana, cocaine, hallucinogens, and inhalants) and alcohol use. Protective factors for nonmedical prescription drug use among rural adolescents included school enrollment and living in a 2-parent household. Conclusions: Rural adolescents were significantly more likely than urban adolescents to report nonmedical prescription drug use. However, these results suggest there are multiple potential points of intervention to prevent initiation or progression of use among rural adolescents including preventing school dropout, increased parental involvement, and increased access to health, mental health, and substance abuse treatment. ©2011 American Medical Association. All rights reserved.
Bell K.Y.,CDM |
Wells M.J.M.,Midway College |
Traexler K.A.,CDM Inc. |
Pellegrin M.-L.,HDR |
And 2 more authors.
Water Environment Research | Year: 2011
Water and wastewater quality research and management pertaining to emerging pollutants, chemical or biological, for which discussion of occurrence surveys, fate and transport investigations, treatment processes, modeling, and/or toxicity/risk assessment appearing in the peerreviewed literature during 2010, are presented. Copyright © 2011 Water Environment Federation.