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Sinha M.,Rgkar Medical College Kolkata | Sanyal D.,Midnapore Medical College Midnapore
International Medical Journal | Year: 2012

Objectives: Compare frequency of life events in depressed women with non-depressed control, time lag between life event and commencement of depressive illness, correlation between severity of life events and magnitude of illness. Design: Cross-sectional study. Materials and Methods: A total of 101 female subjects suffering from depression were randomly chosen from the out-patient department of Psychiatry. Another 101 healthy women devoid of mental illness served as the control group. Both subjects and the control were given questionnaires containing Presumptive Stressful Life events Scale (PSLES) and the Hamilton Depression Rating Scale (HAMD). They enlisted the number of life events experienced within a year prior to the onset of depression. Final stress score was calculated from the frequency of life events and severity of depression graded by HAMD scale. Time lag between stressor and onset of depression along with correlation between stressful life event and precipitation of depression were ascertained. Results: Cases showed higher number of mean stressful life events. Stress score was higher in the depressed. Median duration of depression was 6 months and a time lag of 9 months between the stressor and onset of illness. Women suffered from moderate degree of depression but there was no correlation between life events and illness magnitude. Conclusion: This study reflects the need for understanding the etiological role of life events. © 2012 Japan International Cultural Exchange Foundation & Japan Health Sciences University.

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