Middle Georgia State College is a public, four-year, residential institution offering bachelor's and associate's degrees, as well as some certificates, to students on five campuses in Middle Georgia, and online everywhere. Wikipedia.
PubMed | Vilnius Gediminas Technical University, Vilnius University and Middle Georgia State College
Type: Journal Article | Journal: PloS one | Year: 2015
Several natural and synthetic flavone derivatives have been reported to inhibit formation of amyloid fibrils or to remodel existing fibrils. These studies suggest that the numbers and positions of hydroxyl groups on the flavone rings determine their effectiveness as amyloid inhibitors. In many studies the primary method for determining the effectiveness of inhibition is measuring Thioflavin T (ThT) fluorescence. This method demonstrably results in a number of false positives for inhibition. We studied the effects of 265 commercially available flavone derivatives on insulin fibril formation. We enhanced the effectiveness of ThT fluorescence measurements by fitting kinetic curves to obtain halftime of aggregation (t50). Maximal values of ThT fluorescence varied two fold or more in one third of all cases, but this did not correlate with changes in t50. Changes in t50 values were more accurate measures of inhibition of amyloid formation. We showed that without a change in an assay, but just by observing complete kinetic curves it is possible to eliminate numbers of false positive and sometimes even false negative results. Examining the data from all 265 flavones we confirmed previous observations that identified the importance of hydroxyl groups for inhibition. Our evidence suggests the importance of hydroxyl groups at locations 5, 6, 7, and 4, and the absence of a hydroxyl group at location 3, for inhibiting amyloid formation. However, the main conclusion is that the positions are not additive. The structures and their effects must be thought of in the context of the whole molecule.
News Article | November 3, 2016
A new list from leading higher education and online student resource provider AffordableCollegesOnline.org has ranked the Best Online Colleges in Georgia for 2016-2017. Comparing more than a dozen statistics on affordability and program variety, schools at the top of the list include Columbus State University, Brenau University, Shorter University, Albany State University and Truett-McConnell College among four-year institutions, and Atlanta Technical College, Augusta Technical College, Central Georgia Technical College, Georgia Piedmont Technical College and Wiregrass Georgia Technical College among two-year institutions. "Among large urban areas, Atlanta is 7th in the nation in college enrollment,” said Dan Schuessler, CEO and Founder of AffordableCollegesOnline.org. "More students are seeking the flexibility that online colleges in Georgia offer. This list highlights the schools offering the best combination of quality and value when it comes to online education.” There are specific qualifications schools must meet to make the Best Online Colleges in Georgia list. Only colleges and universities that are accredited are considered, and each must hold public or private not-for-profit standing. Cost and affordability minimums are also set; in-state tuition must fall under $5,000 annually for two-year institutions and under $25,000 annually for four-year institutions to qualify. Scoring for each school is determined by analysis of a variety of statistics, including financial aid availability and breadth of online program options. Find where each of Georgia’s Best Online Colleges ranks and learn more about the methodology used to compile each list at the link below: The following schools are recognized as the 2016-2017 Best Two-Year Online Colleges in Georgia: The following schools are recognized as the 2016-2017 Best Four-Year Online Colleges in Georgia: Albany State University Armstrong Atlantic State University Beulah Heights University Brenau University Clayton State University College of Coastal Georgia Columbus State University Dalton State College Fort Valley State University Georgia College and State University Georgia Regents University Georgia Southern University Kennesaw State University Luther Rice University & Seminary Middle Georgia State College Reinhardt University Shorter University Thomas University Toccoa Falls College Truett-McConnell College University of North Georgia University of West Georgia Valdosta State University AffordableCollegesOnline.org began in 2011 to provide quality data and information about pursuing an affordable higher education. Our free community resource materials and tools span topics such as financial aid and college savings, opportunities for veterans and people with disabilities, and online learning resources. We feature higher education institutions that have developed online learning environments that include highly trained faculty, new technology and resources, and online support services to help students achieve educational and career success. We have been featured by nearly 1,100 postsecondary institutions and nearly 120 government organizations.
Nord J.H.,Oklahoma State University |
Paliszkiewicz J.,Warsaw University of Life Sciences |
Koohang A.,Middle Georgia State College
Journal of Computer Information Systems | Year: 2014
The number of individuals engaging in social technologies for both personal and business reasons is staggering. This phenomenon is growing exponentially and fast becoming an integrated, cross platform experience which will impact every individual online. Social technologies used specifically by organizations for business support, the purposes and the benefits realized are addressed in this paper. Based on research results and a review of related literature, two issues are addressed: 1) How organizations can rethink their social strategy to gain competitive advantage; and 2) How social technologies education should be incorporated into the curriculum so students are prepared for life beyond graduation.
Kwak M.,Middle Georgia State College |
Leroy G.,Claremont Graduate University |
Leroy G.,University of Arizona |
Martinez J.D.,Arizona Cancer Center |
Harwell J.,Claremont Graduate University
Journal of Biomedical Informatics | Year: 2013
Although biomedical information available in articles and patents is increasing exponentially, we continue to rely on the same information retrieval methods and use very few keywords to search millions of documents. We are developing a fundamentally different approach for finding much more precise and complete information with a single query using predicates instead of keywords for both query and document representation. Predicates are triples that are more complex datastructures than keywords and contain more structured information. To make optimal use of them, we developed a new predicate-based vector space model and query-document similarity function with adjusted tf-idf and boost function. Using a test bed of 107,367 PubMed abstracts, we evaluated the first essential function: retrieving information. Cancer researchers provided 20 realistic queries, for which the top 15 abstracts were retrieved using a predicate-based (new) and keyword-based (baseline) approach. Each abstract was evaluated, double-blind, by cancer researchers on a 0-5 point scale to calculate precision (0 versus higher) and relevance (0-5 score). Precision was significantly higher ( p<. .001) for the predicate-based (80%) than for the keyword-based (71%) approach. Relevance was almost doubled with the predicate-based approach-2.1 versus 1.6 without rank order adjustment ( p<. .001) and 1.34 versus 0.98 with rank order adjustment ( p<. .001) for predicate-versus keyword-based approach respectively. Predicates can support more precise searching than keywords, laying the foundation for rich and sophisticated information search. © 2013 Elsevier Inc.
Ku C.-H.,Middle Georgia State College |
Leroy G.,Claremont Graduate University
ACM International Conference Proceeding Series | Year: 2013
With an increasing number of anonymous crime tips and reports being filed and digitized, it is generally difficult for crime analysts to process and analyze crime reports efficiently. We are developing a decision support system (DSS), combining Natural Language Processing (NLP) techniques, a document similarity measure, and machine learning, i.e., a Naïve Bayes' classifier, to support crime analysis and classify which crime reports discuss the same and different crime. The DSS is developed with text mining techniques and evaluated with an active crime analyst. We report here on an experiment that includes two datasets with 40 and 60 crime reports and 16 different types of crimes for each dataset. The results show that our system achieved the highest classification accuracy (94.82%), while the crime analyst's classification accuracy (93.74%) is slightly lower. Copyright 2013 ACM.
Kwak M.,Middle Georgia State College |
Leroy G.,Claremont Graduate University |
Kim M.,University of California at Irvine
International Journal of Biomedical Engineering and Technology | Year: 2012
We describe a new biomedical search engine that enables visual searching and utilises predicates instead of phrases. We report on the development and evaluation of the triple parser, the most essential component of the search engine, which extracts the necessary predicates from the biomedical text. Using texts from three biomedical related sites (N = 180), we compared the parser's output with a gold standard independently created by a medical expert. The parser achieved more than 91% precision and recall. Its individual components showed different strengths with Finite State Automata being excellent for achieving high recall, while Support Vector Machines improved the precision. Copyright © 2012 Inderscience Enterprises Ltd.
Koohang A.,Middle Georgia State College |
Paliszkiewicz J.,Warsaw University of Life Sciences
Journal of Computer Information Systems | Year: 2013
Factor analysis was used to empirically validate an active learning model that asserts knowledge construction in e-learning is achieved through active learning in three stages (underpinning, ownership, and engaging). Each stage is referred to as a component that is comprised of a number of elements or factors essential to the design of active learning in e-learning, leading to successful construction of knowledge. The findings of this study implied that the components in the model were empirically validated to be reliable and interpretable among their associated factors. Conclusions are drawn from the findings. Recommendations are made for further study.
Harman K.,Oklahoma Baptist University |
Koohang A.,Middle Georgia State College |
Paliszkiewicz J.,Warsaw University of Life Sciences
Industrial Management and Data Systems | Year: 2014
Purpose-Gamification has been studied in many areas, i.e. marketing, education, training, and psychology. There has been an increased interest in the topic of gamification among scholars in the past several years. The purpose of this paper is therefore to use citation network analysis and explore changes in scholarly interest in the topic of gamification. As a result, four study hypotheses were developed: H1a: the "other" category publications (books, proceedings, etc.) will have a significantly larger frequency when compared with "journal" publications; H1b: the trend line of the frequency of publications will most closely fit the S-curve of Adoption in the adoption of innovations or the spread of new ideas as postulated by Rogers (2003); H2a: there will be a negative correlation between graph density and the number of vertices (publications); and H2b: there will be a positive correlation between average geodesic distance (AVGD) and the number of vertices (publications).Design/methodology/approach-Data were collected from three searches for all published works that contained the word "gamification" in the titles of publication (the unit of analysis) from 2010 to 2013. The sampling was conducted via Google Scholar, amazon.com, and the academic library databases, i.e. EBSCO Search, JStor Scholarly Journal Archive, PsychArticles, and WorldCat. Data were analyzed using frequency counts and citation network. NodeXL is a highly structured workbook that includes multiple worksheets and computational functions necessary to store, represent, and analyze a network.Findings-All four hypotheses were supported; the "other" category accounted for a significantly larger number of publications with the word "gamification" in the title; the trend line of the frequency of publications will most closely fit the S-curve of Adoption in the adoption of innovations or the spread of new ideas as postulated by Rogers (2003); there was a negative correlation between graph density and the number of vertices (publications); and there was a positive correlation between AVGD and the number of vertices (publications).Research limitations/implications-It is highly improbable that a "pure" or "random" sample of publications could be collected because it is highly probable that there exists no known, i.e. identifiable and verifiable "true" population of works that include gamification in the title.Practical implications-The study findings have three major implications. The first takes in scholarly communication and the development of scientific knowledge. The findings imply that scholarly communication follows patterns similar to the adoption of innovation. The second implication deals with the topic known as "gamification." The study findings imply that scholars believe gamification is worthy of serious study as the network of scholars studying gamification is increasing. The third implication of our study relates to the methods used to study scholarly communication. The study findings imply that network analysis can be used to understand how a new concept can be vetted by the scientific community.Originality/value-The citation network analysis of this study provided tangible evidence of how new concepts are vetted, i.e. adopted. Citation network studies thus offer promise for a deeper understanding of scholarly communication and the adoption of new research topics and fields of inquiry. In addition, the findings indicate that "gamification" is a potentially fruitful topic for scholars to continue to explore. © Emerald Group Publishing Limited.
Hughes N.M.,High Point University |
Carpenter K.L.,High Point University |
Cannon J.G.,Middle Georgia State College
Journal of Plant Physiology | Year: 2013
The association between plant water stress and synthesis of red, anthocyanin pigments in leaves has led some plant biologists to propose an osmotic function of leaf reddening. According to this hypothesis, anthocyanins function as a solute in osmotic adjustment (OA), contributing to depression of osmotic potential (Ψπ) and maintenance of turgor pressure during drought-stressed conditions. Here we calculate the percent contribution of anthocyanin to leaf Ψπ during OA in two angiosperm evergreen species, Galax urceolata and Gaultheria procumbens. Both species exhibit dramatic leaf reddening under high light during winter, concomitant with declines in leaf water potential and accumulation of solutes. Data previously published by the authors on osmotic potential at full turgor (Ψπ,100) of G. urceolata and G. procumbens leaves before and after leaf reddening were used to estimate OA. In vivo molar concentrations of anthocyanin, glucose, fructose, and sucrose measured from the same individuals were converted to pressure equivalents using the Ideal Gas Law, and percent contribution to OA was estimated. Estimated mean OA during winter was -0.7MPa for G. urceolata and -0.8MPa for G. procumbens. In vivo concentrations of anthocyanin (3-10mM) were estimated to account for ∼2% of OA during winter, and comprised <0.7% of Ψπ,100 in both species. Glucose, fructose, and sucrose combined accounted for roughly 50 and 80% of OA for G. urceolata and G. procumbens, respectively, and comprised ∼20% of Ψπ,100. We observed that a co-occurring, acyanic species (Vinca minor) achieved similar OA without synthesizing anthocyanin. We conclude that anthocyanins represent a measurable, albeit meager, component of OA in red-leafed evergreen species during winter. However, due to their low concentrations, metabolic costliness relative to other osmolytes, and striking red color (unnecessary for an osmotic function), it is unlikely that they are synthesized solely for an osmoprotectant role. © 2012.
Kraybill D.B.,Elizabethtown College |
Gilliam J.M.,Middle Georgia State College
Journal of Agromedicine | Year: 2012
This commentary describes the challenges of child safety interventions in Old Order Amish and Mennonite communities in North America. It proposes nine culturally sensitive interventions appropriate for these separatist communities. © 2012 Copyright Taylor and Francis Group, LLC.